知搜-全球专利检索

  1. Login
  2. Sign Up

Search Results

144 records (took 0.026 seconds)

    Method of Hemostasis
    1.
    发明申请
    Method of Hemostasis 审中-公开

    公开(公告)号：US20190247537A1

    公开(公告)日：2019-08-15

    申请号：US16396561

    申请日：2019-04-26

    Applicant: NATIONAL INSTITUTE FOR MATERIALS SCIENCE

    Inventor： Tetsushi TAGUCHI

    IPC: A61L24/10 ,  A61L24/00

    CPC classification number: A61L24/104 ,  A61L15/32 ,  A61L24/0005 ,  A61L24/10 ,  A61L31/04

    Abstract: A method of hemostasis includes the step of applying a hemostatic agent to an affected site of a subject, the hemostatic agent consisting of a first agent comprising a gelatin derivative having a hydrophobic group bonded to the gelatin via an imino group, wherein the gelatin derivative has (a) a weight average molecular weight of from 10,000 to 50,000, (b) the hydrophobic group, which is an alkyl group having 6 to 18 carbon atoms; and (c) a molar ratio of imino group/amino group of the gelatin derivative ranging from 1/99 to 30/70; and a second agent including a crosslinking agent for the gelatin derivative.

    REINFORCED ADHESIVE COMPLEX COACERVATES AND METHODS OF MAKING AND USING THEREOF
    5.
    发明申请
    REINFORCED ADHESIVE COMPLEX COACERVATES AND METHODS OF MAKING AND USING THEREOF 有权
    增强粘合复合材料及其制备和使用方法

    公开(公告)号：US20160250375A1

    公开(公告)日：2016-09-01

    申请号：US15131583

    申请日：2016-04-18

    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION

    Inventor： Russell J. STEWART

    IPC: A61L24/04 ,  A61L24/06 ,  A61L24/02 ,  A61L24/10

    CPC classification number: A61L24/046 ,  A61L24/0015 ,  A61L24/02 ,  A61L24/043 ,  A61L24/06 ,  A61L24/10 ,  A61L27/26 ,  A61L27/54 ,  A61L2300/62 ,  A61L2430/16 ,  C08F8/00 ,  C08F8/06 ,  C08L89/00

    Abstract: Described herein is the synthesis of reinforced adhesive complex coacervates and their use thereof. The reinforced adhesive complex coacervates are composed of (a) at least one polycation, (b) at least one polyanion, and (c) a reinforcing component. The adhesive complex coacervates described herein can be subsequently cured to produce strong, cohesive adhesives. The reinforced adhesive complex coacervates have several desirable features when compared to conventional adhesives. The reinforced adhesive complex coacervates are effective in wet or underwater applications. The reinforced adhesive complex coacervates described herein, being phase separated from water, can be applied underwater without dissolving or dispersing into the water. The reinforced adhesive complex coacervates have numerous biological applications as bioadhesives and bioactive delivery devices. In particular, the reinforced adhesive complex coacervates described herein are particularly useful in underwater applications and situations where water is present such as, for example, wet tissues in physiological conditions.

    Abstract translation: 本文描述的是增强粘合剂复合凝聚层的合成及其用途。 增强粘合剂复合物凝聚层由（a）至少一种聚阳离子，（b）至少一种聚阴离子和（c）增强组分组成。 随后可以固化本文所述的粘合剂复合物凝聚层以产生强的粘结粘合剂。 当与常规粘合剂相比时，增强粘合剂复合物凝聚层具有几个期望的特征。 增强粘合剂复合物凝聚层在湿法或水下应用中是有效的。 本文所述的与水相分离的增强粘合剂复合物凝聚层可以在水中施加而不溶解或分散在水中。 增强粘合剂复合物凝聚层具有生物粘合剂和生物活性递送装置的许多生物应用。 特别地，本文所述的增强粘合剂复合物凝聚层在水下应用和存在水的情况下特别有用，例如生理条件下的湿纸巾。

    PROCESS FOR MAKING DRY AND STABLE HEMOSTATIC COMPOSITIONS
    8.
    发明申请
    PROCESS FOR MAKING DRY AND STABLE HEMOSTATIC COMPOSITIONS 审中-公开
    制备干燥和稳定的HEMOSTATIC组合物的方法

    公开(公告)号：US20150367022A1

    公开(公告)日：2015-12-24

    申请号：US14804084

    申请日：2015-07-20

    Applicant: Baxter International Inc. ,  Baxter Healthcare S.A.

    Inventor： Andreas Goessl ,  Atsushi Edward Osawa ,  Cary J. Reich

    IPC: A61L24/04 ,  A61K38/39 ,  B65B55/02 ,  A61K9/19 ,  B65B3/00 ,  B65B5/12 ,  A61K38/48 ,  A61L24/00

    CPC classification number: A61L24/043 ,  A61K9/0014 ,  A61K9/1658 ,  A61K9/19 ,  A61K38/39 ,  A61K38/4833 ,  A61L24/0015 ,  A61L24/10 ,  A61L24/106 ,  A61L2300/418 ,  A61L2300/802 ,  A61L2400/04 ,  A61L2400/06 ,  B65B3/003 ,  B65B5/12 ,  B65B55/02 ,  C12Y304/21005 ,  Y10T428/13

    Abstract: Described is a process for making a dry and stable hemostatic composition, said process comprising a) providing a first component comprising a dry preparation of a coagulation inducing agent, b) providing a second component comprising a dry preparation of a biocompatible polymer suitable for use in hemostasis, c) providing said first component and said second component in a combined form in a final container, c1) either by filling said first component and said second component into said final container so as to obtain a dry mixture in said final container, c2) or by providing said first component or said second component in said final container and adding said second component or said first component so as to obtain a combination of said first component with said second component in said final container, d) finishing the final container to a storable pharmaceutical device containing said first component and said second component in a combined form as a dry and stable hemostatic composition.

    Abstract translation: 描述了制备干燥和稳定的止血组合物的方法，所述方法包括a）提供包含凝结诱导剂的干制剂的第一组分，b）提供第二组分，其包含适于用于 止血，c）以最终容器中的组合形式提供所述第一组分和所述第二组分，c1）通过将所述第一组分和所述第二组分填充到所述最终容器中以在所述最终容器中获得干混合物，c2 ）或通过在所述最终容器中提供所述第一组分或所述第二组分并加入所述第二组分或所述第一组分以获得所述第一组分与所述最终容器中的所述第二组分的组合，d）将最终容器整理成 一种包含所述第一组分和所述第二组分的可储存药物装置，其为组合形式，为干和稳定的止血组合物 。

Patent Agency Ranking