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公开(公告)号：US20240159766A1
公开(公告)日：2024-05-16
申请号：US18545200
申请日：2023-12-19
Applicant: Meso Scale Technologies, LLC.
Inventor： Charles M. CLINTON , Eli N. GLEZER , Bandele JEFFREY-COKER , Sandor L. KOVACS , Sudeep M. KUMAR , George SIGAL , Carl STEVENS , Michael VOCK
CPC classification number: G01N33/582 , B01L3/50255 , B01L3/5085 , B67B7/24 , G01N21/6452 , G01N21/66 , G01N33/5302 , G01N35/028 , G01N35/1011 , G01N35/1079 , G01N35/1081 , G01N2035/0405 , G01N35/1002 , G01N35/109 , Y10T83/9314
Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
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公开(公告)号：US20250060361A1
公开(公告)日：2025-02-20
申请号：US18938922
申请日：2024-11-06
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Anahit AGHVANYAN , Eli N. GLEZER , John KENTEN , George SIGAL , Martin STENGELIN
IPC: G01N33/53 , C12Q1/6804 , G01N21/66 , G01N21/76 , G01N21/77 , G01N33/533 , G01N33/543 , G01N33/569 , G01N33/58
Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.
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公开(公告)号：US20240382969A1
公开(公告)日：2024-11-21
申请号：US18671149
申请日：2024-05-22
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. GLEZER , Bandele JEFFREY-COKER , Kenneth PAGE , Sandor KOVACS , Sudeep KUMAR , Kristian ROTH
IPC: B01L3/00 , F16K11/074
Abstract: Assay cartridges are described that have a plurality of chambers and a fluidic network that includes fluidic conduits and a multi-port valve designed to selectively connect the valve inlet and one valve outlet through a fluidic connector in the valve as the remaining valve outlets are scaled.
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公开(公告)号：US20240347167A1
公开(公告)日：2024-10-17
申请号：US18595584
申请日：2024-03-05
Applicant: MESO SCALE TECHNOLOGIES, LLC. , THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
Inventor： William F. BLAKELY , Eli N. GLEZER , John H. KENTEN , Sudeep KUMAR , Anu MATHEW , Natalia I. OSSETROVA , George SIGAL
CPC classification number: G16H20/40 , G01N27/3273 , G01N33/6893 , G01N35/00 , G01T1/00 , G01T1/02 , G01N2333/70535 , G01N2333/70578 , G01N2800/40 , G01N2800/60
Abstract: The present invention relates to methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. The invention also relates to algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.
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公开(公告)号：US20220341843A1
公开(公告)日：2022-10-27
申请号：US17733036
申请日：2022-04-29
Applicant: Meso Scale Technologies, LLC.
Inventor： Nicholas ANDERSON , Jeffery DEBAD , Eli N. GLEZER , Sudeep KUMAR , Noel LAWRENCE , Kenneth PAGE , George SIGAL , Sharon WEST
Abstract: Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, thy reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge.
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Patent Agency Ranking
公开(公告)号：US20240293822A1
公开(公告)日：2024-09-05
申请号：US18436879
申请日：2024-02-08
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Eli N. GLEZER , Stephen HIGGINS , Sandor KOVACS , Sudeep KUMAR , Kenneth PAGE , Kristian ROTH , George SIGAL
CPC classification number: B01L7/525 , B01L3/5027 , B01L2200/027 , B01L2200/0605 , B01L2200/0621 , B01L2200/0631 , B01L2200/10 , B01L2200/146 , B01L2200/16 , B01L2300/0645 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/0883 , B01L2400/0487 , B01L2400/0688 , B01L2400/0694 , C12Q1/686
Abstract: Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.
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公开(公告)号：US20240280786A1
公开(公告)日：2024-08-22
申请号：US18596909
申请日：2024-03-06
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Ian D. CHAMBERLIN , Charles M. CLINTON , Eli N. GLEZER , Bandele JEFFREY-COKER , Manish KOCHAR , Sandor KOVACS , D.T. LE , Aaron LEIMKUEHLER , George SIGAL , Leo TABAKIN , Jon WILLOUGHBY
CPC classification number: G02B7/36 , G01N21/253 , G01N21/6452 , G01N35/028
Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.
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公开(公告)号：US20220019053A1
公开(公告)日：2022-01-20
申请号：US17492187
申请日：2021-10-01
Applicant: Meso Scale Technologies, LLC.
Inventor： Ian CHAMBERLIN , Charles M. CLINTON , Eli N. GLEZER , Bandele JEFFREY-COKER , Manish KOCHAR , Sandor KOVACS , D.T. Le , Aaron LEIMKUEHLER , George SIGAL , Leo TABAKIN , Jon WILLOUGHBY
Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.
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公开(公告)号：US20180154353A1
公开(公告)日：2018-06-07
申请号：US15882914
申请日：2018-01-29
Applicant: MESO SCALE TECHNOLOGIES, LLC
Inventor： Eli N. GLEZER , Bandele JEFFREY-COKER , Jeffery D. DEBAD , Sudeep M. KUMAR , George B. SIGAL , Gisbert SPIELES , Michael TSIONSKY , Michael WARNOCK
IPC: B01L3/00 , G01N33/543
CPC classification number: B01L3/5025 , B01L3/5085 , B01L2200/12 , B01L2200/16 , B01L2300/0636 , B01L2300/0645 , B01L2300/0829 , B01L2300/0851 , B01L2300/0858 , B01L2300/105 , G01N33/54366 , G01N33/54393 , Y10S436/809
Abstract: We describe assay modules (e.g., assay plates, cartridges, multi-well assay plates, reaction vessels, etc.), processes for their preparation, and method of their use for conducting assays. Reagents may be present in free form or supported on solid phases including the surfaces of compartments (e.g., chambers, channels, flow cells, wells, etc.) in the assay modules or the surface of colloids, beads, or other particulate supports. In particular, dry reagents can be incorporated into the compartments of these assay modules and reconstituted prior to their use in accordance with the assay methods. A desiccant material may be used to maintain and stabilize these reagents in a dry state.
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公开(公告)号：US20250012822A1
公开(公告)日：2025-01-09
申请号：US18894461
申请日：2024-09-24
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Eli N. GLEZER , Carl EDENS , Bandele JEFFREY-COKER , Sandor KOVACS , Christopher FRYE
IPC: G01N35/00 , B01F31/22 , B01F101/23 , B06B1/16 , G01N33/543 , G01N35/10
Abstract: The present invention relates to a system for performing assays on a solid phase to measure the level of analyte in a sample. Such a system may perform immunoassays using electrochemiluminescence (ECL) including a counterbalanced orbital shaking apparatus for assay consumables.
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