公开(公告)号：US20210190778A1

公开(公告)日：2021-06-24

申请号：US17132380

申请日：2020-12-23

Applicant: Meso Scale Technologies, LLC.

Inventor： Anahit AGHVANYAN ,  Eli N. GLEZER ,  John KENTEN ,  George SIGAL ,  Martin STENGELIN

IPC: G01N33/543 ,  G01N33/569 ,  G01N33/53 ,  G01N33/533 ,  C12Q1/6804 ,  G01N21/66 ,  G01N21/76 ,  G01N21/77 ,  G01N33/58

Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.

公开(公告)号：US20240018571A1

公开(公告)日：2024-01-18

申请号：US17999076

申请日：2021-05-18

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： John KENTEN ,  Jacob N. WOHLSTADTER

IPC: C12Q1/6818

CPC classification number: C12Q1/6818

Abstract: The invention relates to methods, oligonucleotide reagents, compositions, and kits for nucleic acid detection.

公开(公告)号：US20240159746A1

公开(公告)日：2024-05-16

申请号：US18548444

申请日：2022-02-28

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Michael TSIONSKY ,  John KENTEN

IPC: G01N33/543 ,  G01N33/58

CPC classification number: G01N33/54306 ,  G01N33/582 ,  G01N2458/10 ,  G01N2458/30 ,  G01N2474/00

Abstract: Described herein are methods, systems and kits for conducting an assay for one or more analytes of interest in a sample. In one aspect, a method is provided for conducting a multiplexed binding assay for a plurality of analytes of interest in a sample. In one aspect, the assay includes an analyte binding step and a detection step. In one aspect, the analyte binding step is separated from the detection step.

公开(公告)号：US20220099661A1

公开(公告)日：2022-03-31

申请号：US17434938

申请日：2020-02-28

Applicant: Meso Scale Technologies, LLC.

Inventor： John KENTEN ,  Mikayla HIGGINS ,  George SIGAL

IPC: G01N33/533 ,  C07F15/00 ,  G01N33/58 ,  C12Q1/6816 ,  G01N21/64 ,  G01N21/66

Abstract: The present invention is directed to assay methods and compounds and kits used in such assays.

公开(公告)号：US20250060361A1

公开(公告)日：2025-02-20

申请号：US18938922

申请日：2024-11-06

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Anahit AGHVANYAN ,  Eli N. GLEZER ,  John KENTEN ,  George SIGAL ,  Martin STENGELIN

IPC: G01N33/53 ,  C12Q1/6804 ,  G01N21/66 ,  G01N21/76 ,  G01N21/77 ,  G01N33/533 ,  G01N33/543 ,  G01N33/569 ,  G01N33/58

Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.

公开(公告)号：US20230020070A1

公开(公告)日：2023-01-19

申请号：US17849917

申请日：2022-06-27

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： John KENTEN ,  George SIGAL ,  Alexander K. TUCKER-SCHWARTZ

IPC: G01N21/64 ,  C07F15/00 ,  C12Q1/6816 ,  G01N21/66 ,  G01N33/533 ,  G01N33/58

Abstract: The invention relates to methods, compositions, kits, and assay systems for assay signal amplification. Also provided herein is a signal amplification reagent, wherein the signal amplification reagent is an antibody or antigen-binding fragment thereof.

公开(公告)号：US20220003766A1

公开(公告)日：2022-01-06

申请号：US17246360

申请日：2021-04-30

Applicant: Meso Scale Technologies, LLC.

Inventor： Jacob N. WOHLSTADTER ,  George SIGAL ,  Anu MATHEW ,  Anastasia AKSYUK ,  David ROUTENBERG ,  Martin STENGELIN ,  John KENTEN ,  Timothy J. BREAK ,  Seth B. HARKINS ,  Michael TSIONSKY

IPC: G01N33/569 ,  C12Q1/70

Abstract: The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.

公开(公告)号：US20240229110A1

公开(公告)日：2024-07-11

申请号：US18544734

申请日：2023-12-19

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： John KENTEN ,  Galina NIKOLENKO ,  John Robert PETTERSSON

IPC: C12Q1/6825 ,  C12Q1/682

CPC classification number: C12Q1/6825 ,  C12Q1/682 ,  C12Q1/6806

Abstract: The invention provides novel components for conducting assays, e.g., sandwich immunoassays, methods utilizing the novel components, and compositions and kits comprising the novel components.

公开(公告)号：US20230175043A1

公开(公告)日：2023-06-08

申请号：US17607731

申请日：2020-04-30

Applicant: Meso Scale Technologies, LLC.

Inventor： John KENTEN ,  Sudeep KUMAR ,  Galina NIKOLENKO ,  Laukik SARDESAI ,  Alexander K. TUCKER-SCHWARTZ ,  George SIGAL ,  Seth Beebe HARKINS ,  Robert UMEK ,  Timothy J. BREAK ,  Laure MOLLER

IPC: C12Q1/6825

CPC classification number: C12Q1/6825 ,  C12Q1/6837 ,  C12Q2600/16

Abstract: Oligonucleotides, methods and kits are provided for detecting, identifying or quantifying one or more target analytes in a sample as well as methods for immobilizing oligonucleotides onto a support surface.

公开(公告)号：US20220357318A1

公开(公告)日：2022-11-10

申请号：US17813965

申请日：2022-07-21

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Anahit AGHVANYAN ,  Eli N. GLEZER ,  John KENTEN ,  George SIGAL ,  Martin STENGELIN ,  David ROUTENBERG

IPC: G01N33/543 ,  C12Q1/6832 ,  C12Q1/6837 ,  C12Q1/6844

Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.