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1.发明授权Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject 有权用于调节脊椎动物受试者中棕色脂肪组织活性的方法，装置和系统公开(公告)号：US09238133B2
公开(公告)日：2016-01-19
申请号：US13199566
申请日：2011-09-01
Applicant: Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Stephen L. Malaska , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
Inventor： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Stephen L. Malaska , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
CPC classification number: A61N1/0534 , A61F7/106 , A61F7/12 , A61F2007/0002 , A61F2007/0056 , A61F2007/0075 , A61F2007/009 , A61F2007/0093 , A61F2007/029 , A61F2007/101 , A61F2007/126 , A61N1/36 , A61N1/3605 , A61N5/025 , A61N5/04
Abstract: Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more passive cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, wherein at least a portion of the one or more passive cooling elements is configured to be implantable, and wherein the one or more passive cooling elements includes a first portion configured to be in association with the one or more tissues to be cooled, and a second portion configured to be placed in association with one or more tissues adjacent to an external epidermal tissue of the vertebrate subject.
Abstract translation: 本文公开了用于治疗脊椎动物受试者中的疾病，病症或病症的装置，系统和方法。 提供了一种装置，其包括被配置为施加到脊椎动物的一个或多个组织的一个或多个被动冷却元件，所述脊椎动物经受至少一种脊椎动物受试者的棕色脂肪组织的活性，其中至少一部分一个或多个 被动冷却元件被构造成可植入，并且其中所述一个或多个被动冷却元件包括构造成与所述一个或多个要冷却的组织相关联的第一部分，以及第二部分，其被配置为与一个或多个被冷却元件 与脊椎动物受试者的外表皮组织相邻的更多组织。
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公开(公告)号：US09205204B2
公开(公告)日：2015-12-08
申请号：US13567995
申请日：2012-08-06
Applicant: Mahalaxmi Gita Bangera , Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.
Inventor： Mahalaxmi Gita Bangera , Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.
CPC classification number: A61B34/10 , A61B17/3403 , A61B2017/3411 , A61B2034/108 , A61B2090/363 , A61M5/422 , A61M5/427 , A61M5/46 , A61M2205/13 , A61M2207/00 , A61M2210/0606 , B29C64/386 , B33Y50/02 , B33Y80/00 , G05B19/4099 , G05B2219/35134 , G05B2219/49007 , G06F17/5086
Abstract: Wearable injection guides and manufacture and use thereof are described, which include: a rigid needle-penetrable material having an inner surface and an outer surface, the inner surface having form-fitting contours substantially conforming to a topography of a body region of an individual and the outer surface including one or more fiducials indication of at least one treatment parameter.
Abstract translation: 描述了可穿戴式注射引导件及其制造和使用，其包括：具有内表面和外表面的刚性可针穿透材料，内表面具有基本上符合个人身体区域的形貌的形状配合轮廓， 所述外表面包括至少一个治疗参数的一个或多个基准指示。
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公开(公告)号：US09135686B2
公开(公告)日：2015-09-15
申请号：US11588193
申请日：2006-10-25
Applicant: Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
Inventor： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Clarence T. Tegreene , Thomas A. Weaver , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC classification number: G06T5/006 , G06T7/0012 , G06T2207/30008
Abstract: Certain aspects can relate to obtaining at least one image information that can be distorted at least partially resulting from an at least a portion of at least one distorting feature. Certain aspects can relate to determining the at least one relative orientation of the at least the portion of the at least one distorting feature relative to the at least one image information. Certain aspects can relate to computationally compensating at least some of the distortion of the at least the portion of the at least one distorting feature from the at least one image information based at least in part on the distortion characterizing imaging information as based on the at least one relative orientation of the at least the portion of the at least one distorting feature relative to the at least one image information.
Abstract translation: 某些方面可以涉及获得可至少部分地由至少一个失真特征的至少一部分导致的失真的至少一个图像信息。 某些方面可以涉及确定至少一个失真特征的至少一部分相对于该至少一个图像信息的至少一个相对取向。 至少部分地基于至少基于至少一个图像信息的失真表征成像信息来计算地补偿至少一个失真特征的至少一部分的失真的至少一些失真的某些方面 所述至少一个扭曲特征的至少一部分相对于所述至少一个图像信息的一个相对取向。
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公开(公告)号：US09107692B2
公开(公告)日：2015-08-18
申请号：US11526192
申请日：2006-09-22
Applicant: Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Thomas A. Weaver , Lowell L. Wood, Jr.
Inventor： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Michael A. Smith , Thomas A. Weaver , Lowell L. Wood, Jr.
IPC: E04H1/00 , A61B17/3211 , A61B17/3201 , A61B19/00 , A61L2/00 , A61L2/10 , A61B17/32 , A61B17/00
CPC classification number: A61B17/3211 , A61B17/32002 , A61B17/3201 , A61B90/40 , A61B2017/00022 , A61B2017/00061 , A61B2017/00084 , A61B2090/064 , A61L2/0011 , A61L2/10
Abstract: Sectioning tools that emit self-sterilizing radiation. In one approach, the radiation is ultraviolet and/or plasmonic.
Abstract translation: 发射自消毒辐射的切割工具。 在一种方法中，辐射是紫外线和/或等离子体激元。
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5.发明授权Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject 有权用于调节脊椎动物受试者中棕色脂肪组织活性的方法，装置和系统公开(公告)号：US09011510B2
公开(公告)日：2015-04-21
申请号：US13068422
申请日：2011-05-09
Applicant: Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Stephen L. Malaska , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
Inventor： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Edward K. Y. Jung , Eric C. Leuthardt , Stephen L. Malaska , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
CPC classification number: A61F7/02 , A61F7/007 , A61F7/106 , A61F7/12 , A61F2007/0002 , A61F2007/0011 , A61F2007/0056 , A61F2007/0075 , A61F2007/009 , A61F2007/0093 , A61F2007/0226 , A61F2007/0233 , A61F2007/029 , A61F2007/101 , A61F2007/126 , A61N1/0534 , A61N1/36 , A61N1/36014 , A61N1/3605 , A61N1/36053 , A61N1/3606 , A61N1/36135 , A61N2/002 , A61N2/004 , A61N5/025 , A61N5/04 , A61N7/00 , A61N2007/0008
Abstract: Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, wherein at least a portion of the one or more cooling elements is configured to be implantable, and a programmable controller configured to provide instructions to the one or more cooling elements in response to information regarding one or more physiological conditions of the vertebrate subject.
Abstract translation: 本文公开了用于治疗脊椎动物受试者中的疾病，病症或病症的装置，系统和方法。 提供了一种装置，其包括一个或多个冷却元件，其被配置为施加到脊椎动物的一个或多个组织，以调节脊椎动物受试者的褐色脂肪组织的至少一种活性，其中所述一个或多个冷却 元件被配置为可植入的，并且可编程控制器被配置为响应于关于脊椎动物对象的一个或多个生理状况的信息向所述一个或多个冷却元件提供指令。
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Patent Agency Ranking
公开(公告)号：US09005263B2
公开(公告)日：2015-04-14
申请号：US12592976
申请日：2009-12-03
Applicant: Edward S. Boyden , Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
Inventor： Edward S. Boyden , Ralph G. Dacey, Jr. , Gregory J. Della Rocca , Joshua L. Dowling , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Nathan P. Myhrvold , Dennis J. Rivet , Paul Santiago , Michael A. Smith , Todd J. Stewart , Elizabeth A. Sweeney , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC: A61F7/12 , A61L2/03 , A61F2/30 , A61L2/00 , A61F2/00 , A61F2/48 , A61N1/20 , A61N1/372 , A61N1/378
CPC classification number: A61F2/02 , A61F2/30 , A61F2002/009 , A61F2002/30087 , A61F2002/3067 , A61F2002/30677 , A61F2002/3068 , A61F2002/3084 , A61F2002/30932 , A61F2002/481 , A61F2002/482 , A61F2250/0002 , A61F2250/0068 , A61F2310/00616 , A61L2/0011 , A61L2/0023 , A61L2/0029 , A61L2/0088 , A61L2/025 , A61L2/03 , A61N1/205 , A61N1/36 , A61N1/37252 , A61N1/3785 , A61N1/3787
Abstract: Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.
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7.发明授权公开(公告)号：US08849441B2
公开(公告)日：2014-09-30
申请号：US12590034
申请日：2009-10-30
Applicant: Edward S. Boyden , Daniel B. Cook , Roderick A. Hyde , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
Inventor： Edward S. Boyden , Daniel B. Cook , Roderick A. Hyde , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
IPC: G06F19/00 , A61K31/00 , A61K9/16 , A61K9/00 , A61K31/70 , A61K38/48 , A61K9/08 , A61K31/7008 , A61K41/00 , A61K51/12 , A61K31/337 , A61K33/00 , A61K9/19 , A61K38/38 , A61K45/06 , A61K39/00
CPC classification number: G06F19/00 , A61K9/0019 , A61K9/0021 , A61K9/007 , A61K9/08 , A61K9/1611 , A61K9/1617 , A61K9/1641 , A61K9/1664 , A61K9/1688 , A61K9/19 , A61K31/00 , A61K31/337 , A61K31/70 , A61K31/7008 , A61K31/7088 , A61K33/00 , A61K38/38 , A61K38/4833 , A61K38/4886 , A61K39/00 , A61K41/0004 , A61K45/06 , A61K51/1244 , B33Y80/00 , A61K2300/00
Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one substrate.
Abstract translation: 本文公开的某些实施方案涉及关于冷冻颗粒的组合物，方法，装置，系统和产品。 在某些实施方案中，冷冻颗粒包括低温下的材料。 在某些实施方案中，冷冻颗粒提供用于递送特定试剂的载体。 在某些实施方案中，将冷冻颗粒施用于至少一种底物。
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公开(公告)号：US08798932B2
公开(公告)日：2014-08-05
申请号：US12586071
申请日：2009-09-15
Applicant: Edward S. Boyden , Daniel B. Cook , Roderick A. Hyde , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
Inventor： Edward S. Boyden , Daniel B. Cook , Roderick A. Hyde , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
IPC: G06F19/00 , A61M37/00 , A61K9/00 , A61K31/7088 , A61K9/16 , A61K9/24 , A61K38/38 , A61K9/14 , A61K38/48 , A61K31/70 , A61K33/00 , A61K31/337 , A61K39/145 , A61K31/00 , A61K45/06 , C07K16/28 , A61K31/74 , A61K9/08 , C07K16/30 , A61K9/19 , A61K9/20 , A61K41/00 , C07K16/22 , A61K9/28 , A61K9/12 , A61K39/00
CPC classification number: A61K9/0021 , A61K9/0019 , A61K9/007 , A61K9/08 , A61K9/12 , A61K9/143 , A61K9/1611 , A61K9/1641 , A61K9/1664 , A61K9/1688 , A61K9/19 , A61K9/209 , A61K9/2095 , A61K9/2866 , A61K31/00 , A61K31/337 , A61K31/505 , A61K31/519 , A61K31/59 , A61K31/70 , A61K31/7088 , A61K31/74 , A61K33/00 , A61K38/38 , A61K38/4833 , A61K38/4886 , A61K39/00 , A61K39/12 , A61K39/145 , A61K41/0004 , A61K45/06 , A61K2039/505 , A61K2039/54 , A61M37/0015 , A61M2037/0023 , A61M2037/003 , A61M2205/02 , B33Y80/00 , C07K16/22 , C07K16/283 , C07K16/2842 , C07K16/2878 , C07K16/30 , C12N2760/16034 , G06F19/00 , G06F19/3456 , G16H50/50 , Y02A50/464 , Y02A50/466 , Y02A50/472 , Y02A90/26 , Y10T83/222 , A61K2300/00
Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
Abstract translation: 本文公开的某些实施方案涉及关于冷冻颗粒的组合物，方法，装置，系统和产品。 在某些实施方案中，冷冻颗粒包括低温下的材料。 在某些实施方案中，冷冻颗粒提供用于递送特定试剂的载体。 在某些实施方案中，将冷冻颗粒施用于至少一种生物组织。
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公开(公告)号：US08793075B2
公开(公告)日：2014-07-29
申请号：US12290690
申请日：2008-10-31
Applicant: Edward S. Boyden , Roderick A. Hyde , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
Inventor： Edward S. Boyden , Roderick A. Hyde , Eric C. Leuthardt , Nathan P. Myhrvold , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
CPC classification number: G06F19/3456 , A61K9/14 , A61M5/3015 , A61M37/0069 , A61M2205/3306 , G06F19/00 , G06F19/18 , G06F19/3468 , G06F19/3481 , G06F19/36 , G06Q50/22 , Y02A90/22 , Y02A90/26 , A61K2201/02 , A61K2201/101
Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
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公开(公告)号：US08789536B2
公开(公告)日：2014-07-29
申请号：US11998152
申请日：2007-11-27
Applicant: Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Dennis J. Rivet , Michael A. Smith , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
Inventor： Edward S. Boyden , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Dennis J. Rivet , Michael A. Smith , Charles Whitmer , Lowell L. Wood, Jr. , Victoria Y. H. Wood
CPC classification number: A61M31/002 , A61B5/0008 , A61B5/036 , A61B5/073 , A61B5/076 , A61B5/14503 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/42 , A61B5/4839 , A61B5/6882 , A61B7/008
Abstract: Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more.
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