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公开(公告)号：US09205204B2
公开(公告)日：2015-12-08
申请号：US13567995
申请日：2012-08-06
Applicant: Mahalaxmi Gita Bangera , Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.
Inventor： Mahalaxmi Gita Bangera , Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.
CPC classification number: A61B34/10 , A61B17/3403 , A61B2017/3411 , A61B2034/108 , A61B2090/363 , A61M5/422 , A61M5/427 , A61M5/46 , A61M2205/13 , A61M2207/00 , A61M2210/0606 , B29C64/386 , B33Y50/02 , B33Y80/00 , G05B19/4099 , G05B2219/35134 , G05B2219/49007 , G06F17/5086
Abstract: Wearable injection guides and manufacture and use thereof are described, which include: a rigid needle-penetrable material having an inner surface and an outer surface, the inner surface having form-fitting contours substantially conforming to a topography of a body region of an individual and the outer surface including one or more fiducials indication of at least one treatment parameter.
Abstract translation: 描述了可穿戴式注射引导件及其制造和使用，其包括：具有内表面和外表面的刚性可针穿透材料，内表面具有基本上符合个人身体区域的形貌的形状配合轮廓， 所述外表面包括至少一个治疗参数的一个或多个基准指示。
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2.发明申请BREAST IMPLANT WITH COVERING, ANALYTE SENSORS AND INTERNAL POWER SOURCE 有权具有覆盖，分析传感器和内部电源的BREAST植入物公开(公告)号：US20130338770A1
公开(公告)日：2013-12-19
申请号：US13495275
申请日：2012-06-13
Applicant: Edward S. Boyden , Gregory J. Della Rocca , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
IPC: A61F2/12
CPC classification number: A61F2/12 , A61B5/076 , A61B5/14503 , A61B5/1451 , A61B5/14542 , A61B5/14546 , A61B5/14735
Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; at least one fluid-permeable cover, the cover completely enveloping the shell; a plurality of sensor modules attached to the shell, the sensor modules oriented to detect one or more analytes in a fluid between the shell and the cover, the sensor modules positioned at a distance from each other, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules.
Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 至少一个流体可透过的盖，所述盖完全包围所述壳; 多个传感器模块，其附接到所述壳体，所述传感器模块定向成检测所述壳体和所述盖子之间的流体中的一种或多种分析物，所述传感器模块彼此间隔一定距离，其中所述多个传感器模块中的每一个包括 唯一标识符; 以及可操作地附接到所述多个传感器模块的至少一个电源。
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公开(公告)号：US20130338768A1
公开(公告)日：2013-12-19
申请号：US13495212
申请日：2012-06-13
Applicant: Edward S. Boyden , Gregory J. Della Rocca , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
IPC: A61F2/12
CPC classification number: A61F2/12
Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of sensor modules attached to the shell, the sensor modules oriented to detect one or more analytes in a fluid adjacent to the shell, the sensor modules positioned at a distance from each other, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules.
Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 多个传感器模块，其附接到壳体，所述传感器模块被定向成检测邻近所述壳体的流体中的一种或多种分析物，所述传感器模块相互间隔一定距离，其中所述多个传感器模块中的每一个包括唯一的 标识符 以及可操作地附接到所述多个传感器模块的至少一个电源。
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4.发明授权公开(公告)号：US09144488B2
公开(公告)日：2015-09-29
申请号：US13495252
申请日：2012-06-13
Applicant: Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
CPC classification number: A61F2/12 , A61B5/0031 , A61B5/076 , A61B5/14546 , A61B5/4312 , A61B5/686 , A61B5/6867 , A61B2560/0219 , A61F2250/0085 , A61F2250/0096
Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the plurality of sensor modules oriented to detect one or more analytes in a fluid adjacent to the shell, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.
Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 以及多个传感器模块，其附接到壳体并且彼此间隔一定距离，多个传感器模块中的每一个被定向成检测与壳体相邻的流体中的一种或多种分析物，其中多个传感器模块中的每一个包括 唯一的标识符并被配置为利用从外部源发送的能量。
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5.发明授权Breast implant with regionalized analyte sensors responsive to external power source 有权具有响应外部电源的区域化分析物传感器的乳房植入物公开(公告)号：US08808373B2
公开(公告)日：2014-08-19
申请号：US13495310
申请日：2012-06-13
Applicant: Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
IPC: A61F2/24
CPC classification number: A61F2/12 , A61B5/0031 , A61B5/14503 , A61B5/1451 , A61B5/14546 , A61B5/14735 , A61B5/4312 , A61B5/686 , A61B5/6867 , A61B2562/046 , A61F2250/0001 , A61F2250/0002
Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.
Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 从所述壳体的外表面延伸的多个突起，所述突起形成与所述壳体的外表面相邻的多个隔室; 至少一个液体可渗透的盖附接到突起，所述盖完全包围壳体和多个突起; 以及多个传感器模块，其附接到壳体并且彼此间隔一定距离，每个传感器模块被定向成检测多个隔室中的一个内的流体中的一种或多种分析物，其中多个传感器模块 包括唯一的标识符并被配置为利用从外部源发送的能量。
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Patent Agency Ranking
6.发明授权Breast implant with regionalized analyte sensors and internal power source 有权具有区域化分析物传感器和内部电源的乳房植入物公开(公告)号：US08795359B2
公开(公告)日：2014-08-05
申请号：US13495299
申请日：2012-06-13
Applicant: Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
IPC: A61F2/12
CPC classification number: A61F2/12 , A61B5/0031 , A61B5/076 , A61B5/14503 , A61B5/14507 , A61B5/14546 , A61B5/14735 , A61B5/4312 , A61B5/686 , A61B5/6867 , A61B2560/0214 , A61B2560/0219 , A61B2560/0443 , A61B2562/028 , A61B2562/06 , A61B2562/162 , A61B2562/168 , G01N33/528 , G01N33/57415
Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; a plurality of sensor modules attached to the shell, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules.
Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 从所述壳体的外表面延伸的多个突起，所述突起形成与所述壳体的外表面相邻的多个隔室; 至少一个液体可渗透的盖附接到突起，所述盖完全包围壳体和多个突起; 多个传感器模块，其附接到所述壳体，所述传感器模块中的每一个被定向以检测所述多个隔室中的一个内的流体中的一种或多种分析物，其中所述多个传感器模块中的每一个包括唯一标识符; 以及可操作地附接到所述多个传感器模块的至少一个电源。
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7.发明申请BREAST IMPLANT WITH COVERING AND ANALYTE SENSORS RESPONSIVE TO EXTERNAL POWER SOURCE 有权具有覆盖和分析传感器的外部植入物对外部电源的响应公开(公告)号：US20130338771A1
公开(公告)日：2013-12-19
申请号：US13495288
申请日：2012-06-13
Applicant: Edward S. Boyden , Gregory J. Della Rocca , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Paul Duesterhoft , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
IPC: A61F2/12
CPC classification number: A61B5/686 , A61B5/076 , A61B5/4312 , A61B5/4848 , A61B5/4851 , A61F2/12
Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; at least one fluid-permeable cover, the cover completely enveloping the shell; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid between the shell and the cover, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.
Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 至少一个流体可透过的盖，所述盖完全包围所述壳; 以及多个传感器模块，其附接到壳体并且彼此间隔一定距离，每个传感器模块被定向成检测壳体和盖子之间的流体中的一种或多种分析物，其中多个传感器模块中的每一个包括 唯一的标识符并被配置为利用从外部源发送的能量。
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8.发明授权公开(公告)号：US09744379B2
公开(公告)日：2017-08-29
申请号：US14004504
申请日：2012-03-13
Applicant: Shyam Bharat , Karl Antonin Bzdusek , Parag Jitendra Parikh , Camille Elizabeth Noel
Inventor： Shyam Bharat , Karl Antonin Bzdusek , Parag Jitendra Parikh , Camille Elizabeth Noel
CPC classification number: A61N5/1037 , A61N5/1031 , A61N2005/1072
Abstract: A treatment planning system (106) for generating patient-specific treatment margins. The system (106) includes one or more processors (142). The processors (142) are programmed to receive a radiation treatment plan (RTP) for irradiating a target (122) over the course of one or more treatment fractions. The RTP including one or more treatment margins around the target (122) and a planned dose distribution for the target (122). The processors (142) are further programmed to receive motion data for at least one of the treatment fractions of the RTP from one or more target surrogates (124), calculate a motion-compensated dose distribution for the target (122) using the motion data and the planned dose distribution, compare the motion-compensated dose distribution to the planned dose distribution, and adjust the treatment margins based on dosimetric differences between the motion-compensated dose distribution and the planned dose distribution.
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公开(公告)号：US09211185B2
公开(公告)日：2015-12-15
申请号：US13495212
申请日：2012-06-13
Applicant: Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
Inventor： Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Robert Langer , Eric C. Leuthardt , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene
IPC: A61F2/12
CPC classification number: A61F2/12
Abstract: Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of sensor modules attached to the shell, the sensor modules oriented to detect one or more analytes in a fluid adjacent to the shell, the sensor modules positioned at a distance from each other, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules.
Abstract translation: 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 多个传感器模块，其附接到壳体，所述传感器模块被定向成检测邻近所述壳体的流体中的一种或多种分析物，所述传感器模块相互间隔一定距离，其中所述多个传感器模块中的每一个包括唯一的 标识符 以及可操作地附接到所述多个传感器模块的至少一个电源。
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公开(公告)号：US09199044B2
公开(公告)日：2015-12-01
申请号：US13567921
申请日：2012-08-06
Applicant: Mahalaxmi Gita Bangera , Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.
Inventor： Mahalaxmi Gita Bangera , Edward S. Boyden , Gregory J. Della Rocca , Daniel Hawkins , Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Robert Langer , Eric C. Leuthardt , Stephen L. Malaska , Terence Myckatyn , Parag Jitendra Parikh , Dennis J. Rivet , Joshua S. Shimony , Michael A. Smith , Elizabeth A. Sweeney , Clarence T. Tegreene , Sharon L. Wolda , Lowell L. Wood, Jr.
CPC classification number: A61B34/10 , A61B17/3403 , A61B2017/3411 , A61B2034/108 , A61B2090/363 , A61M5/422 , A61M5/427 , A61M5/46 , A61M2205/13 , A61M2207/00 , A61M2210/0606 , B29C64/386 , B33Y50/02 , B33Y80/00 , G05B19/4099 , G05B2219/35134 , G05B2219/49007 , G06F17/5086
Abstract: Wearable injection guides and manufacture and use thereof are described, which include: a rigid material formed to substantially conform in shape to a topography of a body region of an individual, the rigid material substantially impenetrable to an injection needle, and the rigid material including one or more injection needle access regions arranged in a treatment pattern.
Abstract translation: 描述了可穿戴的注射引导件及其制造和使用，其包括：刚性材料，形成为基本上符合个体的身体区域的形状，刚性材料基本上不可渗透到注射针，并且刚性材料包括一个 或更多的注射针入口区域以治疗图案排列。
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