Abstract:
The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.
Abstract:
A tray (100) for accommodating a coiled medical device, such as a catheter assembly (700), includes a first compartment (101), a second compartment (102), and a third compartment (103). The catheter assembly (700) and devices associated with a catheterization procedure, such as syringes (701,702) containing sterile water and lubricating jelly and a specimen container (703) can be disposed within the tray. Printed instructions (1001) can be included with the tray (100). One or more layers of wrap material (2200) can be folded about the tray (100) to enclose the tray (100) and other items, such as an additional layer of wrap material (2701), packaged liquid hand sanitizer (2401), and packaged gloves (2402). When a health care services provider (3101) unfolds the wrap material, the same can be used to create a sterile field beneath a patient (3201).
Abstract:
Guiding catheter comprising a first end and a second end, and at least three main portions being: a first linear portion connected to the first end, a second curved portion connected to the first linear portion, a third linear portion, connected to the second curved portion, opposite to the first linear portion, and connected to said second end, characterized in that said second curved portion subtends an angle β from 195° to 240° and in that said third linear portion is provided to engage an active distal tip as fourth portion.
Abstract:
The invention relates to a data communication system (100) and a method that can particularly be applied for communicating data from a medical instrument like a catheter or a guide-wire via a high-speedlink (101). The system (100) comprises (in-vivo) a slave component (150) with a controllable slave clock (153) and a transmitter (151) for transmitting a data signal (ds) that is clocked by the slave clock signal (clk). Moreover, it comprises (ex-vivo) a master component (110) with a clock controller (114,115,116) that receives a master clock signal (ref_clk) and the data signal (ds) and that generates a clock control signal (ccs) for adjusting the slave clock (153) to the master clock (113). The slave clock (153) may thus be realized with low space and energy requirements, e.g. by a voltage controlled oscillator (VCO). Moreover, the link (101) via which the data signal (ds) and the clock control signal (ccs) are exchanged may be realized by just two signal wires.
Abstract:
A nitric oxide delivery device includes a housing that is permeable to nitric oxide. The surface of the housing is modified to detect surface charge or pH (e.g., due to cell adhesion). A working electrode (which is a copper-containing conductive material or a base material coated with a copper-containing conductive material) is positioned inside of the housing. A reference/counter electrode is also positioned inside of the housing, and is electrically isolated from the working electrode. A source of nitrite ions is to be contained within the housing such that it is in contact with the working electrode.
Abstract:
A coronary artery catheter adapted for introducing its distal end into a coronary ostium through an artery includes a catheter body with a lumen formed therein. The catheter body in a natural state includes: a proximal straight section extending distally from a proximal end of the catheter body; a first curved section extending distally from the proximal straight section while being curved; an intermediate straight section extending distally from the first curved section; a second curved section extending distally from the intermediate straight section while being curved; and a distalmost section extending from the second curved section to a distal end of the catheter body. The first curved section and the second curved section, when projected onto a plane on which the first curved section and the intermediate straight section are present, curve in the same direction.
Abstract:
Systems, apparatuses, and methods are disclosed that include an optical fiber adapted to emit light along an axial length of an exterior cylindrical surface of the optical fiber. The optical fiber may emit the axially-emitted light over a narrow radial angle δ, such that the axially-emitted light functions in a manner similar to a slit lamp to enhance visibility of nearly transparent structures within the eye. The axially-emitted light may be produced such that no portion of the light is directed in a proximal direction, thereby preventing a portion of the light from being directed at a surgeon.
Abstract:
A catheter assembly for insertion into the brain. The assembly comprises a first length of tubing made of a first material. A second material surrounds the first length of tubing, the second material being more flexible than the first material and having a hardness of less than 50 Rockwell E. The second material provides damping to the first length of tubing.
Abstract:
A reconfigurable delivery system is disclosed having a multi-lumen delivery catheter configuration that permits the delivery and staged release of a self-expanding main vessel stent-graft and a delivery sheath configuration that permits the introduction of various medical devices for the delivery and implantation of various branch vessel stent-grafts that are to be mated with the main vessel stent-graft. A method is disclosed wherein the delivery system is first used in the multi-lumen delivery catheter configuration to deliver and release a main vessel stent-graft that is configured for placement in the abdominal aorta for treatment of short-neck infrarenal, juxtarenal, and/or suprarenal aneurysms and then used in the delivery sheath configuration to facilitate the delivery of branch vessel stent-grafts that are configured to extend from the main vessel stent-graft into a respective renal artery.
Abstract:
The devices and methods described herein relate to improved structures for removing obstructions from body lumens. Such devices have applicability in through-out the body, including clearing of blockages within the vasculature, by recanalizing or removing the obstruction within the body lumen.