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111 条记录 (耗时 0.039 秒)

    Processes for producing isomaltose and isomaltitol and use thereof
    61.
    发明申请
    Processes for producing isomaltose and isomaltitol and use thereof 有权

    公开(公告)号：US20060240531A1

    公开(公告)日：2006-10-26

    申请号：US10492932

    申请日：2002-10-18

    申请人： Michio Kubota

    发明人： Michio Kubota

    IPC分类号： C12P19/04 ,  C12P19/06

    CPC分类号： C12P19/12

    摘要： The present invention aims to provide a novel process for producing isomaltose and isomaltitol, and uses thereof, and it solves the object by establishing a process for producing isomaltose comprising a step of contacting a saccharide, having the α-1,4 glucosidic linkage as the linkage of non-reducing end and a glucose polymerization degree of at least two, with an α-isomaltosyl-transferring enzyme and an α-isomaltosylglucosaccharide-forming enzyme derived from a specific microorganism; a process for producing isomaltitol using the isomaltose produced by the above process; saccharide compositions comprising the isomaltose and/or the isomaltitol produced by the above processes; and uses thereof.

    Method for inhibiting acrylamide formation and use thereof
    63.
    发明申请
    Method for inhibiting acrylamide formation and use thereof 审中-公开
    抑制丙烯酰胺形成的方法及其用途

    公开(公告)号：US20060194743A1

    公开(公告)日：2006-08-31

    申请号：US10536268

    申请日：2003-11-20

    申请人： Kazuyuki Oku ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Kazuyuki Oku ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： A61K31/70 ,  A61K31/198 ,  A23L3/015

    CPC分类号： A61K8/676 ,  A23L5/00 ,  A23L5/27 ,  A23L7/00 ,  A23L7/111 ,  A23L7/152 ,  A23L19/13 ,  A23L19/15 ,  A23L19/18 ,  A23L25/20 ,  A23L29/045 ,  A23L29/30 ,  A23L33/125 ,  A23L33/175 ,  A23P20/12 ,  A23V2002/00 ,  A61K2800/52 ,  A61Q19/00 ,  A23V2250/0626 ,  A23V2250/0628 ,  A23V2250/0638 ,  A23V2250/0654 ,  A23V2250/0652 ,  A23V2250/061 ,  A23V2250/0632 ,  A23V2250/0648 ,  A23V2250/065 ,  A23V2250/636 ,  A23V2250/06 ,  A23V2250/708

    摘要： An object of the present invention is to establish a method for actively suppressing the formation of acrylamide, which is formed by heating edible materials at a relatively high temperature, and uses thereof, and to provide more safe compositions such as foods, beverages, cosmetics, pharmaceuticals, and intermediates thereof. The present invention solves the above object by providing: a method for suppressing the formation of acrylamide, comprising the steps of incorporating an organic substance having an ability of suppressing the formation of acrylamide into an edible material having a possibility of forming acrylamide by heating and heating the resulting mixture, when heating the edible material; compositions such as foods, beverages, cosmetics, pharmaceuticals, and intermediates thereof, produced by the method, whose possibility of forming acrylamide is suppressed; and compositions such as foods, beverages, cosmetics, pharmaceuticals, and intermediates thereof, having an ability of suppressing the formation of acrylamide, comprising an organic substance having an amino group(s) and/or saccharides having an ability of forming acrylamide and organic substance having an ability of suppressing the formation of acrylamide.

    摘要翻译： 本发明的目的是建立一种主动抑制通过在较高温度下加热可食用材料而形成的丙烯酰胺的形成方法及其用途，并提供更安全的组合物，例如食品，饮料，化妆品， 药物及其中间体。 本发明通过提供以下方法解决了上述目的：提供一种抑制丙烯酰胺形成的方法，包括以下步骤：将具有抑制丙烯酰胺形成抑制能力的有机物掺入到通过加热和加热形成丙烯酰胺的可食用材料 所得混合物在加热食用材料时; 通过该方法制造的食品，饮料，化妆品，药​​物及其中间体的组合物，其形成丙烯酰胺的可能性被抑制; 以及具有抑制丙烯酰胺形成能力的食品，饮料，化妆品，药​​物及其中间体的组合物，包含具有氨基的有机物和/或具有形成丙烯酰胺和有机物质的能力的糖类 具有抑制丙烯酰胺形成的能力。

    Reduction inhibitory agent for active oxygen eliminating activity
    64.
    发明申请
    Reduction inhibitory agent for active oxygen eliminating activity 审中-公开
    还原抑制剂用于活性氧消除活性

    公开(公告)号：US20050065030A1

    公开(公告)日：2005-03-24

    申请号：US10986287

    申请日：2004-11-12

    申请人： Kazuyuki Oku ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Kazuyuki Oku ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： A61K8/60 ,  A61K31/702 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  A61Q19/10 ,  C07H3/06 ,  A61K31/715 ,  A01N43/48

    CPC分类号： A61Q19/00 ,  A23B7/08 ,  A23L3/3436 ,  A23L3/3562 ,  A23L29/035 ,  A61K8/60 ,  A61K31/702 ,  A61K2800/522 ,  A61Q11/00 ,  A61Q19/02 ,  A61Q19/08 ,  A61Q19/10 ,  C07H3/06

    摘要： Disclosed are a reduction inhibitory agent for active oxygen eliminating activity, comprising: (a) at least 10% (w/w) of a cyclotetrasaccharide having a basic cyclic structure in Chemical Formula 1, on a dry solid basis; and Chemical Formula 1: (b) at least one member selected from the group consisting of saccharides and edible fibers; a method for inhibiting the reduction of active oxygen eliminating activity, comprising a step of incorporating at least one percent (w/w) of a cyclotetrasaccharide having a basic cyclic structure in Chemical Formula 1 to a plant substance, on a dry solid basis, into said plant substance with active oxygen eliminating activity in an aqueous system; and a composition obtainable by incorporating at least one percent (w/w) of a cyclotetrasaccharide having a basic cyclic structure in Chemical Formula 1 to said plant substance, on a dry solid basis, into a plant substance with active oxygen eliminating activity to inhibit the reduction of the activity of said plant substance.

    摘要翻译： 公开了一种活性氧消除活性的还原抑制剂，其包括：（a）化学式1中具有碱性环状结构的至少10％（w / w）的干燥固体的环状四糖; 和化学式1：（b）选自由糖类和食用纤维组成的组中的至少一种; 一种抑制活性氧消除活性降低的方法，包括在化学式1中将至少1％（w / w）具有碱性环状结构的环状四糖在干固体中掺入到植物物质中的步骤， 所述植物物质在含水体系中具有活性氧消除活性; 以及通过将化学式1中具有碱性环状结构的至少1％（w / w）的干燥固体的碱性环状结构的所得到的组合物，以干固体的形式掺入到具有活性氧消除活性的植物物质中，以抑制 所述植物物质的活性降低。

    Trehalose phosphorylase, its preparation and uses
    68.
    发明授权
    Trehalose phosphorylase, its preparation and uses 失效
    海藻糖磷酸化酶，其制备及用途

    公开(公告)号：US5910436A

    公开(公告)日：1999-06-08

    申请号：US102644

    申请日：1998-06-23

    申请人： Tetsuya Nakada ,  Michio Kubota ,  Hiroto Chaen ,  Toshio Miyake

    发明人： Tetsuya Nakada ,  Michio Kubota ,  Hiroto Chaen ,  Toshio Miyake

    IPC分类号： A61K38/00 ,  C12N1/21 ,  C12N9/10 ,  C12N15/54 ,  C12P19/18 ,  C07H21/04 ,  C12N1/20 ,  C12N15/00

    CPC分类号： C12N9/1051 ,  C12P19/18 ,  A61K38/00

    摘要： A thermostable trehalose phosphorylase which is obtainable from microorganisms of the genus Thermoanaerobium and which hydrolyzes trehalose in the presence of an inorganic phosphoric acid to form D-glucose and .beta.-D-glucose-1-phosphoric acid. The trehalose phosphorylase can be also prepared by recombinant DNA technology. When the enzyme is allowed to contact with .beta.-D-glucose-1-phosphoric acid as a saccharide donor in the presence of other saccharides, glucosyl-transferred saccharides including glucosyl-D-galactoside, which are conventionally known but scarcely obtainable, can be produced on an industrial-scale and in a relatively-low cost.

    摘要翻译： 一种热稳定的海藻糖磷酸化酶，其可从Thermoanaerobium属的微生物获得，并且在无机磷酸存在下水解海藻糖以形成D-葡萄糖和β-D-葡萄糖-1-磷酸。 海藻糖磷酸化酶也可以通过重组DNA技术制备。 当酶在其他糖类存在下与β-D-葡萄糖-1-磷酸作为糖供体接触时，通常已知但几乎不可获得的包括葡糖基-D-半乳糖苷的葡糖基转移的糖可以是 以工业规模生产，成本相对较低。

    DNA encoding enzyme, recombinant DNA and enzyme, transformant, and their preparation and uses
    69.
    发明授权
    DNA encoding enzyme, recombinant DNA and enzyme, transformant, and their preparation and uses 失效
    DNA编码酶，重组DNA和酶，转化体及其制备和用途

    公开(公告)号：US5871994A

    公开(公告)日：1999-02-16

    申请号：US714537

    申请日：1996-09-16

    申请人： Michio Kubota ,  Keiji Tsusaki ,  Kazuhiko Maruta ,  Toshiyuki Sugimoto

    发明人： Michio Kubota ,  Keiji Tsusaki ,  Kazuhiko Maruta ,  Toshiyuki Sugimoto

    IPC分类号： C12N1/21 ,  C12N9/90 ,  C12N15/56 ,  C12P19/12 ,  C12N9/24 ,  C12N9/26

    CPC分类号： C12P19/12 ,  C12N9/90

    摘要： A DNA encoding an enzyme, which forms non-reducing saccharides having trehalose structure as an end unit from amylaceous saccharides having a degree of glucose polymerization of 3 or higher, enables an industrial-scale production of a recombinant enzyme with such enzyme activity. Non-reducing saccharides obtainable by the recombinant enzyme can be used in a variety of food products, cosmetics, pharmaceuticals and feeds because of their substantial non-reducibility, mild and high-quality sweetness, adequate viscosity, and moisture-retaining ability.

    摘要翻译： 从葡萄糖聚合度为3以上的淀粉糖形成具有海藻糖结构的非还原性糖类作为末端单元的酶的DNA能够实现具有这种酶活性的重组酶的工业规模生产。 可以通过重组酶获得的非还原性糖可以用于各种食品，化妆品，药​​物和饲料中，因为它们具有显着的不可还原性，温和和高品质的甜度，足够的粘度和保湿能力。

    Recombinant enzyme for converting maltose into trehalose from pimelobacter sp.
    70.
    发明授权
    Recombinant enzyme for converting maltose into trehalose from pimelobacter sp. 失效
    用于从麦芽糖转化成麦芽糖至海藻糖的重组酶。

    公开(公告)号：US5763228A

    公开(公告)日：1998-06-09

    申请号：US528199

    申请日：1995-09-14

    申请人： Michio Kubota ,  Keiji Tsusaki ,  Toshiyuki Sugimoto

    发明人： Michio Kubota ,  Keiji Tsusaki ,  Toshiyuki Sugimoto

    IPC分类号： C12N9/90 ,  C12P19/24 ,  C12P19/12 ,  C12N9/24 ,  C12N15/56

    CPC分类号： C12N9/90 ,  C12P19/24

    摘要： A recombinant enzyme, having a molecular weight of about 57,000-67,000 daltons on SDS-PAGE and a pI of about 4.1-5.1 on isoelectrophoresis, which converts maltose into trehalose and vice versa. Depending on the enzymatic conditions, the enzyme forms about 70 w/w % of trehalose when acts on maltose, while about 20 w/w % of maltose when acts on trehalose. The culture of a transformant, prepared by introducing into a host a recombinant DNA containing a DNA coding for the enzyme and a self-replicable vector, facilitates the industrial-scale production of trehalose.

    摘要翻译： 重组酶，SDS-PAGE上分子量约57,000-67,000道尔顿，在电泳上的pI约为4.1-5.1，将麦芽糖转化为海藻糖，反之亦然。 根据酶的条件，当作用于麦芽糖时，该酶形成约70w / w％的海藻糖，而当作用于海藻糖时约为20w / w％的麦芽糖。 通过向宿主中引入含有编码酶的DNA和自我复制载体的重组DNA制备的转化体的培养有利于海藻糖的工业规模生产。