公开(公告)号：US11975133B2

公开(公告)日：2024-05-07

申请号：US18069451

申请日：2022-12-21

申请人： NextKidney SA

发明人： Didier Vecten ,  Ricardo Allendes ,  Paul Vescovo

IPC分类号： A61M1/36 ,  A61M1/14 ,  A61M1/16 ,  A61M1/26 ,  A61M39/10 ,  A61M39/22

CPC分类号： A61M1/3644 ,  A61M1/1524 ,  A61M1/154 ,  A61M1/155 ,  A61M1/1561 ,  A61M1/1565 ,  A61M1/1603 ,  A61M1/1621 ,  A61M1/267 ,  A61M1/362227 ,  A61M1/36224 ,  A61M1/36225 ,  A61M1/362261 ,  A61M1/362265 ,  A61M1/3627 ,  A61M39/10 ,  A61M39/22 ,  A61M1/1566 ,  A61M1/362266 ,  A61M1/3646 ,  A61M2205/3337 ,  A61M2205/50

摘要： A dialysis system may include a blood circuit, a cassette, a subsystem having a processor, a sensor, and a blood pumping mechanism, a housing in which the subsystem is arranged, a movable support arranged in the housing and configured to hold the sensor and/or the blood pumping mechanism of the subsystem, a cassette holder configured to removably receive the cassette, and a loading system. The loading system may be configured to move the movable support, e.g. by an axial movement, to a first position and to a second position relatively to the housing while the cassette holder is fixedly arranged in the housing. The loading system may have an electric motor controlled by the processor, a drive assembly coupled to the electric motor, and a guiding assembly configured to cooperate with the drive assembly.

公开(公告)号：US20240115779A1

公开(公告)日：2024-04-11

申请号：US18275611

申请日：2022-02-08

申请人： FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

发明人： Frank BIERMANN

IPC分类号： A61M1/14 ,  A61M1/36

CPC分类号： A61M1/154 ,  A61M1/36224 ,  A61M2205/3331

摘要： A pressure-measuring device according to the invention has a hydrophobic membrane, which is air permeable in the dry state and air impermeable in a moistened state, and a pressure sensor, which is in mechanical contact with the hydrophobic membrane and which is designed to follow a movement of the membrane. During the filling of a line system, air is separated via the hydrophobic membrane and, in the air-impermeable state, the pressure in the line system is measured by means of the moistened hydrophobic membrane.

公开(公告)号：US20240115777A1

公开(公告)日：2024-04-11

申请号：US18391085

申请日：2023-12-20

申请人： Fenwal, Inc.

发明人： Benjamin E. Kusters ,  Kyungyoon Min

IPC分类号： A61M1/02 ,  A61M1/36 ,  B04B5/04

CPC分类号： A61M1/029 ,  A61M1/362227 ,  A61M1/36224 ,  A61M1/36225 ,  A61M1/362261 ,  A61M1/362265 ,  A61M1/3693 ,  A61M1/3696 ,  B04B5/0442 ,  B04B11/02

摘要： Systems and methods are provided for separating blood into two or more components for collection of red blood cells, plasma, or both red blood cells and plasma. A blood separation system includes a blood separation device and a fluid flow circuit configured to be mounted to the blood separation device. The blood separation device includes a centrifugal separator and a spinning membrane separator drive unit, with the blood being separated into its constituents by the centrifugal separator. Separated plasma may be collected following separation by the centrifugal separator or may first be conveyed from the centrifugal separator into the spinning membrane separator drive unit to separate cellular blood components from the plasma prior to collection of the filtered plasma. The cellular blood components filtered from the plasma may be retained in the circuit as a waste product or may be flushed out of the circuit to a recipient.

公开(公告)号：US11931492B2

公开(公告)日：2024-03-19

申请号：US17363554

申请日：2021-06-30

申请人： Baxter International Inc. ,  Baxter Healthcare SA

发明人： Michael E. Hogard ,  Donald D. Busby ,  Robert W. Childers ,  Yuanpang Samuel Ding ,  Katherine M. Holian ,  Mark E. Jablonski ,  Thomas D. Kelly ,  Shincy J. Maliekkal ,  Rodolfo G. Roger ,  Donald A. Smith ,  Atif M. Yardimci ,  Ying-Cheng Lo

IPC分类号： A61M1/14 ,  A61M1/16 ,  A61M1/28 ,  A61M1/34 ,  A61M1/36

CPC分类号： A61M1/14 ,  A61M1/1522 ,  A61M1/153 ,  A61M1/154 ,  A61M1/155 ,  A61M1/1561 ,  A61M1/15625 ,  A61M1/15632 ,  A61M1/1565 ,  A61M1/16 ,  A61M1/1605 ,  A61M1/1613 ,  A61M1/1635 ,  A61M1/166 ,  A61M1/1696 ,  A61M1/28 ,  A61M1/284 ,  A61M1/288 ,  A61M1/3401 ,  A61M1/341 ,  A61M1/3413 ,  A61M1/3417 ,  A61M1/342 ,  A61M1/3427 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3441 ,  A61M1/3444 ,  A61M1/3458 ,  A61M1/3465 ,  A61M1/3468 ,  A61M1/362223 ,  A61M1/36224 ,  A61M1/362261 ,  A61M1/362262 ,  A61M1/362264 ,  A61M1/362265 ,  A61M2205/12 ,  A61M2205/3334

摘要： A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber.

公开(公告)号：US11896746B2

公开(公告)日：2024-02-13

申请号：US16495893

申请日：2018-03-20

申请人： TERUMO KABUSHIKI KAISHA

发明人： Masatsugu Igarashi

IPC分类号： A61M1/02 ,  A61M1/36 ,  A61M1/34 ,  A61M1/38

CPC分类号： A61M1/0222 ,  A61M1/3496 ,  A61M1/3672 ,  A61M1/3696 ,  A61M1/36222 ,  A61M1/362261 ,  A61M1/362264 ,  A61M1/362265 ,  A61M1/38 ,  A61M1/36224 ,  A61M2205/125 ,  A61M2205/7545 ,  A61M2207/00

摘要： A blood component collection cassette that can trap a foreign object such as a blood-coagulated clot from blood components to be returned to a blood donor and a manufacturing method of the blood component collection cassette are provided.
A sheet-shaped filter member (60) is arranged on a flow path (42) in a cassette main body (40) of a blood component collection cassette (28). A first tube (66) and a second tube (68) are arranged in the cassette main body (40). An inner space (51) of a filter housing unit (54a) is separated by the filter member (60) into a first space (51a) on the side of the first tube (66) and a second space (51b) on the side of the second tube (68).

公开(公告)号：US20240024552A1

公开(公告)日：2024-01-25

申请号：US17814543

申请日：2022-07-25

申请人： William M. Gosney ,  Dale B. Nixon

发明人： William M. Gosney ,  Dale B. Nixon

IPC分类号： A61M1/36 ,  C12N5/00 ,  G01N21/88 ,  G01N33/49 ,  G06T7/00

CPC分类号： A61M1/36224 ,  C12N5/0081 ,  A61M1/3678 ,  G01N21/8851 ,  G01N33/49 ,  G06T7/0014 ,  A61M2205/3313 ,  A61M2205/52 ,  G01N2021/8887 ,  G06T2207/30024

摘要： An operational unit for locating and neutralizing pathogen cells in blood. A cassette has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, the pump is operated to move the identified cells to a processing zone. When each identified cell reaches the processing zone, electric energy is applied to destroy the identified pathogen cells. A pump refills the cassette holding chambers, returns the neutralized-pathogen blood to the patient, and the process is repeated for a treatment time period.

公开(公告)号：US20230381383A1

公开(公告)日：2023-11-30

申请号：US18446323

申请日：2023-08-08

申请人： DEKA Products Limited Partnership

发明人： Dirk A. van der Merwe ,  Kevin L. Grant ,  Michael J. Wilt

IPC分类号： A61M1/16 ,  A61M1/36 ,  A61K33/00 ,  A61M60/427 ,  A61M60/37 ,  A61M1/30 ,  A61M5/172 ,  A61M1/34 ,  G16H20/40 ,  A61M1/14 ,  A61M60/43 ,  A61M1/26 ,  A61M60/837 ,  A61M60/268 ,  A61M60/113 ,  A61M60/851 ,  A61M60/847 ,  A61M60/894 ,  A61M60/892

CPC分类号： A61M1/1601 ,  A61M1/1654 ,  A61M1/166 ,  A61M1/3609 ,  A61K33/00 ,  A61M60/427 ,  A61M60/37 ,  A61M1/362266 ,  A61M1/362227 ,  A61M1/362265 ,  A61M1/301 ,  A61M5/172 ,  A61M1/1692 ,  A61M1/34 ,  A61M1/3627 ,  G16H20/40 ,  A61M1/1668 ,  A61M1/1666 ,  A61M1/3413 ,  A61M1/1524 ,  A61M1/156 ,  A61M1/1605 ,  A61M1/1619 ,  A61M1/341 ,  A61M60/43 ,  A61M1/15632 ,  A61M1/1565 ,  A61M1/36224 ,  A61M1/36225 ,  A61M1/362264 ,  A61M1/267 ,  A61M1/1613 ,  A61M60/837 ,  A61M1/15625 ,  A61M1/154 ,  A61M1/3621 ,  A61M1/1658 ,  A61M1/1664 ,  A61M60/268 ,  A61M60/113 ,  A61M1/3672 ,  A61M1/36226 ,  A61M1/14 ,  A61M1/16 ,  A61M1/1656 ,  A61M60/851 ,  A61M60/847 ,  A61M1/155 ,  A61M2205/3317 ,  A61M2205/3334 ,  A61M2205/3584 ,  A61M1/362261 ,  A61M2205/3368 ,  A61M2205/3313 ,  A61M2205/3379 ,  A61M2205/3324 ,  A61M60/894 ,  Y02A90/10 ,  A61M2205/18 ,  A61M2205/50 ,  A61M60/892 ,  A61M2205/12 ,  A61M2205/3306 ,  Y02A50/30 ,  A61M2205/15 ,  A61M2205/3569 ,  A61M1/3638 ,  A61M2205/3331 ,  A61M2205/52 ,  A61M2205/502 ,  A61M1/1561 ,  A61M2230/65

摘要： Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

公开(公告)号：US20230372598A1

公开(公告)日：2023-11-23

申请号：US18226613

申请日：2023-07-26

申请人： Terumo BCT, Inc.

发明人： Thomas J. FELT ,  Dennis J. HLAVINKA ,  Brian M. HOLMES

IPC分类号： A61M1/36 ,  A61M1/30 ,  A61M1/02 ,  A61M1/38 ,  A61M1/34

CPC分类号： A61M1/3696 ,  A61M1/3646 ,  A61M1/36224 ,  A61M1/304 ,  A61M1/3693 ,  A61M1/362262 ,  A61M1/0272 ,  A61M1/382 ,  A61M1/024 ,  A61M1/362261 ,  A61M1/362265 ,  A61M1/3627 ,  A61M1/3496 ,  A61M1/3601 ,  A61M2205/3334 ,  A61M2205/123 ,  A61M1/3403 ,  A61M2205/12 ,  A61M1/30 ,  A61M2202/0415 ,  A61M2205/3379 ,  A61M2205/50 ,  A61M1/36222 ,  A61M2205/331 ,  A61M1/3639

摘要： Described are embodiments that include methods and devices for separating components from multi-component fluids. Embodiments may involve use of separation vessels and movement of components into and out of separation vessels through ports. Embodiments may involve the separation of plasma from whole blood. Also described are embodiments that include methods and devices for positioning portions, e.g., loops, of disposables in medical devices. Embodiments may involve use of surfaces for automatically guiding loops to position them into a predetermined position.

公开(公告)号：US20230285653A1

公开(公告)日：2023-09-14

申请号：US18117029

申请日：2023-03-03

申请人： Terumo BCT, Inc.

发明人： John PITTINGER ,  Stephanie Lynne ST. GEORGE ,  Taylor POLODNA ,  Bruce ELLINGBOE ,  Charles L. HAKE ,  Evan Christopher PROVAN

IPC分类号： A61M1/36

CPC分类号： A61M1/3656 ,  A61M1/3693 ,  A61M1/36224 ,  A61M1/3623

摘要： A method includes detecting a condition including one or more of a change in flow of a fluid and a change in a composition of the fluid, issuing an alarm in response to the condition detected, lowering a flow rate; and attempting to restart process and increase the flow rate. The change in flow may include a change in pressure. The change in flow may be associated with a collapsed vein. The change in flow of the fluid may include detecting that the flow rate has fallen below a threshold. The change in the composition may be associated with a color. The change in the composition may include using a color sensor to detect one or more of a red, a green, and a blue reflection or transmission to detect red blood cells.