公开(公告)号：US20240027323A1

公开(公告)日：2024-01-25

申请号：US17814548

申请日：2022-07-25

申请人： William M. Gosney ,  Dale B. Nixon

发明人： William M. Gosney ,  Dale B. Nixon

IPC分类号： G01N15/14

CPC分类号： G01N15/1475 ,  G01N2015/0065

摘要： An apparatus for locating and venting pathogen cells in blood. A cassette has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, a pump is operated to move the identified cells to a processing zone. When each identified cell reaches the processing zone, a control voltage is generated to open a valve to vent the identified pathogen cells. The pump refills the cassette holding chambers, returns the processed blood to the patient, and the procedure is repeated for a treatment time period.

公开(公告)号：US20240024558A1

公开(公告)日：2024-01-25

申请号：US17814546

申请日：2022-07-25

申请人： William M. Gosney ,  Dale B. Nixon

发明人： William M. Gosney ,  Dale B. Nixon

IPC分类号： A61M1/36 ,  A61L2/00

CPC分类号： A61M1/3681 ,  A61L2/0011 ,  A61M2205/053

摘要： An operational unit for locating and neutralizing pathogen cells in blood. A cassette has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, the pump is operated to move the identified cells to a processing zone. When each identified cell reaches the processing zone, electric energy is applied to destroy the identified pathogen cells. A pump refills the cassette holding chambers, returns the neutralized-pathogen blood to the patient, and the process is repeated for a treatment time period.

公开(公告)号：US20240024557A1

公开(公告)日：2024-01-25

申请号：US17814538

申请日：2022-07-25

申请人： William M. Gosney ,  Dale B. Nixon

发明人： William M. Gosney ,  Dale B. Nixon

IPC分类号： A61M1/36 ,  A61L2/00

CPC分类号： A61M1/3681 ,  A61L2/0011 ,  A61M2205/053

摘要： An operational unit for locating and neutralizing pathogen cells in blood includes a cassette which has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates the holding chambers and passes light to an underlying sensor array such that the cells in the blood selectively block the light to produce shadow images of the cells. A processor performs pattern recognition to locate the pathogen cells by use of an image library. After the pathogen cells are located, a source of ultraviolet light is activated and UV light is passed through selectively controlled shutters to illuminate only the limited areas that have the identified pathogen cells. Sufficient ultraviolet light energy is applied to destroy the identified cells. A pump refills the cassette holding chambers, returns the neutralized-pathogen blood to the patient, and the process is repeated.

公开(公告)号：US20240033411A1

公开(公告)日：2024-02-01

申请号：US17814539

申请日：2022-07-25

申请人： William M. Gosney ,  Dale B. Nixon

发明人： William M. Gosney ,  Dale B. Nixon

IPC分类号： A61M1/36 ,  G06V20/69 ,  G06V10/147 ,  G06V10/145

CPC分类号： A61M1/36224 ,  A61M1/3678 ,  G06V20/698 ,  G06V20/693 ,  G06V10/147 ,  G06V10/145 ,  A61M2205/3313 ,  A61M2205/52 ,  G06V2201/03

摘要： An operational unit for locating and neutralizing pathogen cells in blood includes a time use cassette which has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood selectively block the light to produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, an electric field is activated in the cassette chamber areas that include the identified pathogen cells. Sufficient electric field energy is applied to destroy the identified pathogen cells. A pump refills the cassette holding chambers, returns the neutralized-pathogen blood to the patient, and the process is repeated for a period of time.

公开(公告)号：US20240024554A1

公开(公告)日：2024-01-25

申请号：US17814545

申请日：2022-07-25

申请人： William M. Gosney ,  Dale B. Nixon

发明人： William M. Gosney ,  Dale B. Nixon

IPC分类号： A61M1/36 ,  A61M60/113 ,  A61M60/279 ,  A61M60/36 ,  A61M60/585 ,  A61M60/847

CPC分类号： A61M1/3678 ,  A61M60/113 ,  A61M60/279 ,  A61M60/36 ,  A61M60/585 ,  A61M60/847 ,  A61M2205/3313

摘要： An operational unit for locating and neutralizing pathogen cells in blood. A cassette has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, the pump is operated to move the identified cells to a processing zone. When each identified cell reaches the processing zone, electric energy is applied to destroy the identified pathogen cells. A pump refills the cassette holding chambers, returns the neutralized-pathogen blood to the patient, and the process is repeated for a treatment time period.

公开(公告)号：US11872333B1

公开(公告)日：2024-01-16

申请号：US17814549

申请日：2022-07-25

申请人： William M. Gosney ,  Dale B. Nixon

发明人： William M. Gosney ,  Dale B. Nixon

IPC分类号： A61M1/36 ,  A61M60/36 ,  A61M60/279 ,  A61M60/113 ,  A61M1/14

CPC分类号： A61M1/1562 ,  A61M1/3672 ,  A61M1/36226 ,  A61M60/113 ,  A61M60/279 ,  A61M60/36

摘要： An apparatus for locating and venting pathogen cells in blood. A cassette has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, a pump is operated to move the identified cells to a processing zone. When each identified cell reaches the processing zone, a control voltage is generated to open a valve to vent the identified pathogen cells. The pump refills the cassette holding chambers, returns the processed blood to the patient, and the procedure is repeated for a treatment time period.

公开(公告)号：US20240024551A1

公开(公告)日：2024-01-25

申请号：US17814547

申请日：2022-07-25

申请人： William M. Gosney ,  Dale B. Nixon

发明人： William M. Gosney ,  Dale B. Nixon

IPC分类号： A61M1/36 ,  A61M60/10

CPC分类号： A61M1/36 ,  A61M60/10 ,  A61M2205/12

摘要： An apparatus for locating and venting pathogen cells in blood. A cassette has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, a pump is operated to move the identified cells to a processing zone. When each identified cell reaches the processing zone, a control voltage is generated to open a valve to vent the identified pathogen cells. The pump refills the cassette holding chambers, returns the processed blood to the patient, and the procedure is repeated for a treatment time period.

公开(公告)号：US20240024550A1

公开(公告)日：2024-01-25

申请号：US17814541

申请日：2022-07-25

申请人： William M. Gosney ,  Dale B. Nixon

发明人： William M. Gosney ,  Dale B. Nixon

IPC分类号： A61M1/36 ,  A61L2/24 ,  A61L2/00

CPC分类号： A61M1/36 ,  A61L2/24 ,  A61L2/0011 ,  A61M2205/3306 ,  A61M2205/12 ,  A61L2202/11 ,  A61L2202/22 ,  A61L2202/14

摘要： An operational unit for locating and neutralizing pathogen cells in blood includes a time use cassette which has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood selectively block the light to produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, an electric field is activated in the cassette chamber areas that include the identified pathogen cells. Sufficient electric field energy is applied to destroy the identified pathogen cells. A pump refills the cassette holding chambers, returns the neutralized-pathogen blood to the patient, and the process is repeated for a period of time.

公开(公告)号：US5373910A

公开(公告)日：1994-12-20

申请号：US45523

申请日：1993-04-08

申请人： Dale B. Nixon

发明人： Dale B. Nixon

IPC分类号： B60K1/04 ,  H01M2/10

CPC分类号： H01M2/1083 ,  B60K1/04 ,  B60L11/1805 ,  B60L11/1822 ,  B60L11/1853 ,  B60L11/1859 ,  B60L11/1861 ,  B60L11/1864 ,  B60L11/1877 ,  B60S5/06 ,  B60K2001/0455 ,  B60L2240/547 ,  B60L2240/549 ,  B60L2250/10 ,  Y02T10/7005 ,  Y02T10/7044 ,  Y02T10/7061 ,  Y02T10/7072 ,  Y02T90/124 ,  Y02T90/14

摘要： A battery-powered vehicle has two batteries which are replaced, rather than recharged in the vehicle. The vehicle is powered by only one battery at a time and that battery is used until substantially all of the energy the battery is exhausted. A discharged battery is replaced while the vehicle operates with the other, nondischarged battery. Preferred batteries have high energy density and may be of a type that is not rechargeable. An example is an aluminum-air battery. The non-rechargeable discharged batteries can be remanufactured to produce new batteries for further use in the vehicle.

摘要翻译： 电池供电的车辆具有更换的两个电池，而不是在车辆中充电。 车辆一次只能由一个电池供电，并且电池被使用，直到电池的电量基本上全部耗尽。 当车辆与其他未充电电池一起工作时，更换已放电的电池。 优选的电池具有高能量密度并且可以是不可再充电的类型。 一个例子是铝 - 空气电池。 不可再充电的电池可以再制造，以生产新的电池，以便在车辆中进一步使用。

公开(公告)号：US20240024546A1

公开(公告)日：2024-01-25

申请号：US17814549

申请日：2022-07-25

申请人： William M. Gosney ,  Dale B. Nixon

发明人： William M. Gosney ,  Dale B. Nixon

IPC分类号： A61M1/36 ,  A61M60/113 ,  A61M60/279 ,  A61M60/36

CPC分类号： A61M1/36226 ,  A61M1/3672 ,  A61M60/113 ,  A61M60/279 ,  A61M60/36

摘要： An apparatus for locating and venting pathogen cells in blood. A cassette has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, a pump is operated to move the identified cells to a processing zone. When each identified cell reaches the processing zone, a control voltage is generated to open a valve to vent the identified pathogen cells. The pump refills the cassette holding chambers, returns the processed blood to the patient, and the procedure is repeated for a treatment time period.