公开(公告)号：US12016989B2

公开(公告)日：2024-06-25

申请号：US17255083

申请日：2019-07-01

Applicant: KABUSHIKI KAISYA ADVANCE

Inventor： Nobuchika Urakabe

IPC: A61M1/36 ,  A61M1/38

CPC classification number: A61M1/3661 ,  A61M1/3639 ,  A61M1/38 ,  A61M2205/3334

Abstract: According to the present invention, blood access formed by a percutaneous terminal for hemodialysis is performed, the percutaneous terminal provided with: a contact body comprising a biocompatible member that comes into contact with skin tissue inside and outside a living body; a tubular body having one end connected to an artery and the other end connected to a vein; a blood removal tubular body having one end connected to a side surface of the tubular body and supplying blood to an external blood circuit; and a retransfusing tubular body having one end connected to the vein and the other end connected to a retransfusing portion of the blood circuit, wherein the other end of the blood removal tubular body and the retransfusing tubular body are located at a central portion of the contact body. Furthermore, provided is a hemodialysis system that is less burdensome for a patient and enables stable blood access.

公开(公告)号：US20240139400A1

公开(公告)日：2024-05-02

申请号：US18403166

申请日：2024-01-03

Applicant: Fenwal, Inc.

Inventor： Matthew J. Schoonover

IPC: A61M1/38 ,  A61B5/00 ,  A61B5/15 ,  A61M1/34 ,  A61M1/36 ,  G16H20/40 ,  G16H30/40 ,  G16H40/63

CPC classification number: A61M1/38 ,  A61B5/150786 ,  A61B5/7485 ,  A61M1/3496 ,  A61M1/3612 ,  A61M1/3672 ,  G16H20/40 ,  G16H30/40 ,  G16H40/63 ,  A61M2202/0429 ,  A61M2205/505 ,  A61M2205/6072 ,  G05B2219/36371

Abstract: A method of processing blood or a blood product using an automated system includes displaying on a display a listing of a plurality of blood processing procedures that may be performed using the system and receiving operator input selecting one of the blood processing procedures that is to be performed. The method includes displaying on the display a list of parameters that are associated with the selected blood processing procedure and receiving operator input selecting a plurality of the parameters that are to populate the display during performance of the procedure. The method includes receiving operator input indicating a format in which the selected parameters are to be presented on the display. The method includes displaying values for the selected plurality of parameters in the indicated format during performance of the specified procedure.

公开(公告)号：US11918721B2

公开(公告)日：2024-03-05

申请号：US17727334

申请日：2022-04-22

Applicant: Baxter International Inc. ,  Baxter Healthcare SA

Inventor： Alex Anping Yu ,  James Grayson ,  Robert W. Childers

IPC: A61M1/28 ,  A61M1/14 ,  A61M1/16 ,  A61M1/34 ,  A61M1/38 ,  B01D61/30 ,  B01D61/32 ,  G16H20/40

CPC classification number: A61M1/282 ,  A61M1/155 ,  A61M1/159 ,  A61M1/16 ,  A61M1/1603 ,  A61M1/28 ,  A61M1/281 ,  A61M1/287 ,  A61M1/341 ,  B01D61/30 ,  B01D61/32 ,  G16H20/40 ,  A61M1/1522 ,  A61M2205/18 ,  A61M2205/3303 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2205/3553 ,  A61M2205/3576 ,  A61M2205/3592 ,  A61M2205/502 ,  A61M2230/005 ,  A61M2230/30

Abstract: An example peritoneal dialysis system is disclosed. The example peritoneal dialysis system includes at least one pump and a memory device configured to store therapy prescriptions including a low ultrafiltration (“UF”) therapy prescription, a first standard UF therapy prescription with a longer duration and a lower dextrose concentration, and a second standard UF therapy prescription with a shorter duration and a higher dextrose concentration. The memory device also stores a schedule indicative as to which of the therapy prescriptions are to be performed on specified dates. The system further includes a logic implementer configured to determine or identify a current date, use the schedule stored in the memory device to select the therapy prescription based on the current date, and control the at least one pump based on the selected therapy prescription to perform a peritoneal dialysis therapy.

公开(公告)号：US11904078B2

公开(公告)日：2024-02-20

申请号：US17334393

申请日：2021-05-28

Applicant: DIALITY INC.

Inventor： Brandon Borillo ,  Tzu Tung Chen ,  Clayton Poppe

IPC: A61M1/16 ,  A61M1/38 ,  B01D46/00

CPC classification number: A61M1/1647 ,  A61M1/1672 ,  A61M1/38 ,  B01D46/0036 ,  A61M2205/3334

Abstract: A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient through the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. Preferably, the hemodialysis system includes a sorbent filter in the dialysate flow path. Furthermore, the hemodialysis machine includes a blood pump, and a pair of dialysate pumps. A processor controls the flow of blood through the blood flow path, and the processor controls the flow of dialysate through the dialysate flow path. In addition, the processor stores a patient treatment plan wherein the flow rate of the dialysate through the dialysate flow path reduces throughout the patient's treatment to maximize the amount of urea removed by the sorbent filter.

公开(公告)号：US11752243B2

公开(公告)日：2023-09-12

申请号：US16332473

申请日：2017-09-12

Applicant: TERUMO KABUSHIKI KAISHA

Inventor： Masatsugu Igarashi

IPC: A61M1/02 ,  A61M1/36 ,  A61M1/38 ,  A61M60/851 ,  A61M60/847 ,  A61M60/554 ,  A61M60/441 ,  A61M60/39 ,  A61M60/279 ,  A61M60/104 ,  B04B5/04 ,  B04B11/02

CPC classification number: A61M1/0236 ,  A61M1/0209 ,  A61M1/0245 ,  A61M1/3621 ,  A61M1/3693 ,  A61M1/38 ,  A61M60/104 ,  A61M60/279 ,  A61M60/39 ,  A61M60/441 ,  A61M60/554 ,  A61M60/847 ,  A61M60/851 ,  B04B5/0442 ,  B04B11/02 ,  A61M2202/0415 ,  A61M2202/0427 ,  A61M2202/0429 ,  A61M2202/0439 ,  A61M2205/12 ,  A61M2205/123 ,  A61M2205/3331

Abstract: A blood component sampling cassette which can be more efficiently manufactured at lower cost as compared to a typical cassette, a blood sampling circuit set, and a blood component sampling system. A blood component sampling cassette (22) includes a cassette main body (23) made of a soft material to which heat sterilization is applicable. The cassette main body (23) is provided with a retransfusion line (44). The retransfusion line (44) is provided with a reservoir (47) configured to temporarily store a blood component to be returned to a blood donor. The reservoir (47) is pressed by a retransfusion pump (49) to discharge the blood component from the reservoir (47).

公开(公告)号：US11730873B2

公开(公告)日：2023-08-22

申请号：US18109547

申请日：2023-02-14

Applicant: FENWAL, INC.

Inventor： Amit J. Patel ,  Samantha M. Planas ,  Walter T. Watts ,  Kyungyoon Min ,  Daniel R. Boggs

IPC: A61M1/34 ,  A61M1/36 ,  A61M1/38 ,  G01N33/48 ,  G16H10/60

CPC classification number: A61M1/3496 ,  A61M1/3607 ,  A61M1/3616 ,  A61M1/3643 ,  A61M1/3672 ,  A61M1/38 ,  A61M1/382 ,  A61M1/385 ,  G01N33/48 ,  G16H10/60 ,  A61M2202/0415 ,  A61M2205/3379 ,  A61M2205/3393 ,  A61M2205/502 ,  A61M2205/505 ,  A61M2230/207

Abstract: A method of collecting plasma includes receiving donor parameters at a controller of a plasma collection device electronically from a donor management system. The method includes storing a target volume for raw plasma which is based at least in part on donor height and weight used to calculate total donor blood volume, the target volume for raw plasma based on the total donor blood volume. The method includes setting the target volume for raw plasma and controlling the plasma collection device to operate draw and return phases to withdraw whole blood from a donor and separate the whole blood into the plasma product and a second blood component comprising red blood cells and to return the second blood component to the donor. The controller operates the draw and return phases until a volume of raw plasma in the collection container equals the target volume of raw plasma.

公开(公告)号：US11623033B2

公开(公告)日：2023-04-11

申请号：US16680819

申请日：2019-11-12

Applicant: TERUMO KABUSHIKI KAISHA

Inventor： Shigeyuki Kimura

IPC: A61M1/36 ,  A61M1/02 ,  A61M1/38 ,  C12N5/078 ,  B04B5/04 ,  B04B11/02

Abstract: A blood component separation device for separating a plurality of blood components from blood sampled from a blood donor, and collecting platelets, includes: an operation unit that calculates a predicted platelet recovery rate from a hematocrit value of the blood and a platelet concentration of the blood, and calculates a recommended processing amount of the blood recommended for collecting a target number of units of platelets on the basis of the calculated predicted platelet recovery rate, wherein the operating unit sets the predicted platelet recovery rate calculated from any the hematocrit value and any the platelet concentration to be smaller by a predetermined value a when the blood donor is female than that when the blood donor is male.

公开(公告)号：US20220305188A1

公开(公告)日：2022-09-29

申请号：US17838902

申请日：2022-06-13

Applicant: Fenwal, Inc.

Inventor： Matthew J. Schoonover

IPC: A61M1/38 ,  G16H40/63 ,  G16H20/40 ,  G16H30/40 ,  A61B5/00 ,  A61B5/15 ,  A61M1/36 ,  A61M1/34

Abstract: A method and automated system for processing blood in which the automated system includes a programmable controller, a database, and an interactive display screen for displaying information and receiving operator input. The programmable controller is configured to automatically control the system to perform the method. Upon activation of the system, the screen displays a listing of different blood processing procedures that may be performed using the system. The operator may then input into the controller an identification of a specified blood processing procedure that is to be performed, such that an initial list of parameters that are associated with the specified blood processing procedure are displayed on the screen. The operator may then input into the controller an identification of the parameters that are to populate the display screen during performance of the procedure and indicate a format in which the selected parameters are to be presented on the display screen. The controller then creates a display for the specified blood processing procedure. Current values of the selected parameters in the selected format are displayed on the screen during performance of the specified procedure. The controller automatically saves an image of the display screen periodically during performance of the specified blood processing procedure, and transfers information from the saved images of the display screens to a procedure record form.

公开(公告)号：US11433260B2

公开(公告)日：2022-09-06

申请号：US16200195

申请日：2018-11-26

Applicant: Gholam A. Peyman

Inventor： Gholam A. Peyman

IPC: A61N7/02 ,  A61K49/22 ,  A61N2/00 ,  A61B5/00 ,  A61M1/38 ,  A61K41/00 ,  A61K47/69 ,  A61K9/00 ,  A61B8/08 ,  A61K9/127 ,  A61K49/00 ,  A61N7/00 ,  A61B5/01 ,  A61K45/06 ,  A61N1/40 ,  A61B8/13 ,  A61N1/36 ,  A61N1/32

Abstract: Cancer treatment methods using thermotherapy and/or enhanced immunotherapy are disclosed herein. In one embodiment, the method comprising the steps of administering a plurality of nanoparticles to target a tumor in a patient, the nanoparticles being coated with an antitumor antibody, cell penetrating peptides (CPPs), and a polymer, and the nanoparticles containing medication and/or gene, and a dye or indicator in the polymer coating, at least some of the nanoparticles attaching to surface antigens of tumor cells so as to form a tumor cell/nanoparticle complex; exciting the nanoparticles using an ultrasound source generating an ultrasonic wave so as to peel off the polymer coating of the nanoparticles, thereby releasing the dye or indicator into the circulation of the patient and the medication and/or gene at the tumor site; and imaging a body region of the patient so as to detect the dye or indicator released into the circulation of the patient.

公开(公告)号：US20220110972A1

公开(公告)日：2022-04-14

申请号：US17499792

申请日：2021-10-12

Applicant: Trevor Percival Castor

Inventor： Trevor Percival Castor

IPC: A61K35/16 ,  A61M1/38

Abstract: The novel coronavirus COVID-19 has caused a worldwide pandemic of enormous proportions resulting in significant levels of morbidity and mortality, tremendous pressures on the healthcare system, personal freedoms and society, and an unprecedented impact on the economies of the United States and the world. There are still significant unknowns about this very contagious and deadly virus, and these unknowns are coupled with no natural immunity. A promising therapeutic strategy is the utilization/transfusion of convalescent plasma from recovered COVID-19 patients. There are, however, risks involved in such transfusions from residual virus and other adventitious viruses and bacteria. These risks can be minimized by the pathogen clearance of convalescent plasma units in a hospital setting. There is an immediate need for the rapid pathogen inactivation/clearance of convalescent plasma units from recovered COVID-19 patients.
The present invention is a physical pathogen reduction and inactivation apparatus and method for controlling or eliminating transfusion-transmittable infections in convalescent plasma from recovered COVID-19 donors. The invention inactivates both nonenveloped and enveloped viruses as well as pathogenic bacteria and parasites in units of human plasma, while retaining the potency of natural biologically-active proteinaceous products in the pathogen-reduced plasma. The invention uses critical, near-critical or supercritical fluids for viral and pathogen reduction of units of donor blood plasma in blood bags. The apparatus is in the form of a transportable mobile unit, where it can be used in hospitals, blood banks, and medical facilities.