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公开(公告)号：US12066017B2
公开(公告)日：2024-08-20
申请号：US18460492
申请日：2023-09-01
IPC分类号： F04B43/02 , A61M1/14 , A61M1/16 , A61M1/28 , F04B7/02 , F04B9/109 , F04B13/02 , F04B23/06 , F04B41/06 , F04B43/00 , F04B43/06 , F04B43/073 , F04B45/02 , F04B45/053 , F04B49/02 , F04B49/22 , F04B53/06 , F04B53/10 , F04B53/16 , F17D3/00 , A61M60/43
CPC分类号： F04B43/026 , A61M1/154 , A61M1/155 , A61M1/1561 , A61M1/15625 , A61M1/1565 , A61M1/16 , A61M1/1605 , A61M1/1639 , A61M1/1656 , A61M1/1664 , A61M1/1666 , A61M1/287 , F04B7/02 , F04B9/109 , F04B13/02 , F04B23/06 , F04B41/06 , F04B43/00 , F04B43/06 , F04B43/0736 , F04B45/02 , F04B45/0536 , F04B49/02 , F04B49/22 , F04B53/06 , F04B53/10 , F04B53/16 , F17D3/00 , A61M60/43 , A61M2205/12 , A61M2205/128 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368 , Y10T137/0324 , Y10T137/0379 , Y10T137/2521 , Y10T137/85978 , Y10T137/86139
摘要： A pumping cassette including a housing having at least two inlet fluid lines and at least two outlet fluid lines. At least one balancing pod within the housing and in fluid connection with the fluid paths. The balancing pod balances the flow of a first fluid and the flow of a second fluid such that the volume of the first fluid equals the volume of the second fluid. The balancing pod also includes a membrane that forms two balancing chambers. Also included in the cassette is at least two reciprocating pressure displacement membrane pumps. The pumps are within the housing and they pump the fluid from a fluid inlet to a fluid outlet line and pump the second fluid from a fluid inlet to a fluid outlet.
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公开(公告)号：US11568043B2
公开(公告)日：2023-01-31
申请号：US16671855
申请日：2019-11-01
发明人： Todd A. Ballantyne , Jon H. Cook , Benjamin E. Colburn , Andrew E. Harner , Corey Christous , Shane Whalen
IPC分类号： G06F21/55 , G06F21/56 , G06F21/50 , G06F21/51 , G06F21/57 , G06F21/62 , G06F21/00 , G16H20/40 , G16H20/17 , G16H40/40 , G16H40/60 , G16H40/63 , G16H40/67 , G05B15/02 , A61M1/16 , A61M1/36 , A61M1/34 , A61M60/43 , A61M60/113 , A61M60/892 , A61M60/894 , A61M60/37 , A61M60/515 , A61M60/538
摘要： A processor of a medical device configured to communicate with a remote server can be programmed to protect the medical device from exposure to unauthorized or malicious software. A system or method to implement this form of protection can include, for example, at least one processor on the medical device, a control software module that controls the operation of the medical device and is executable on the processor, a data management module that manages data flow to and from the control software module from sources external to the medical device, and an agent module that has access to a limited number of designated memory locations in the medical device. In addition, a hemodialysis apparatus can be configured to operate in conjunction with an apparatus for providing purified water from a source such as a municipal water supply or a well. A system for controlling delivery of purified water to the hemodialysis apparatus can comprise a therapy controller of the hemodialysis apparatus configured to communicate with a controller of a water purification device, and a user interface controller of the hemodialysis apparatus configured to communicate with the therapy controller, and to send data to and receive data from a user interface.
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公开(公告)号：US20240352927A1
公开(公告)日：2024-10-24
申请号：US18762769
申请日：2024-07-03
IPC分类号： F04B43/06 , A61M1/14 , A61M1/16 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/427 , A61M60/43 , A61M60/523 , A61M60/546 , A61M60/847 , A61M60/851 , F04B9/109 , F04B13/02 , F04B43/02 , F04B43/073 , F04B45/053 , F04B53/10 , F16K99/00
CPC分类号： F04B43/06 , A61M1/14 , A61M1/154 , A61M1/155 , A61M1/15625 , A61M1/1563 , A61M1/1565 , A61M1/16 , A61M1/1601 , A61M1/1639 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/427 , A61M60/523 , A61M60/546 , A61M60/847 , A61M60/851 , F04B9/109 , F04B13/02 , F04B43/02 , F04B43/073 , F04B43/0733 , F04B45/053 , F04B45/0536 , F04B53/106 , F04B53/1062 , F16K99/0015 , A61M1/153 , A61M60/43 , A61M2205/12 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3368 , Y10T137/0329 , Y10T137/2521 , Y10T137/2931 , Y10T137/7879 , Y10T137/85978 , Y10T137/86139
摘要： A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
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4.发明授权公开(公告)号：US11725645B2
公开(公告)日：2023-08-15
申请号：US16723408
申请日：2019-12-20
发明人： Michael J. Wilt , Dirk A. van der Merwe , James D. Dale , Brian D. Tracey , Kevin L. Grant , Jason A. Demers , Catharine N. Flynn
IPC分类号： F04B43/073 , A61M1/26 , F04B7/02 , F04B43/00 , F17D3/00 , F04B13/02 , F04B9/109 , F04B49/22 , F04B45/02 , F04B53/10 , A61M60/268 , A61M60/113 , A61M60/531 , A61M60/37 , A61M1/36 , A61M1/16 , A61M1/28 , F04B49/06 , F04B53/16 , F04B53/06 , A61M60/523 , A61M60/43 , A61M60/892 , A61M60/894
CPC分类号： F04B43/0733 , A61M1/16 , A61M1/1605 , A61M1/166 , A61M1/1639 , A61M1/1656 , A61M1/1664 , A61M1/1666 , A61M1/267 , A61M1/287 , A61M1/3638 , A61M1/3672 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/523 , A61M60/531 , F04B7/02 , F04B7/0216 , F04B9/109 , F04B13/02 , F04B43/00 , F04B45/02 , F04B49/06 , F04B49/22 , F04B53/06 , F04B53/10 , F04B53/16 , F17D3/00 , A61M60/43 , A61M60/892 , A61M60/894 , A61M2205/12 , A61M2205/128 , A61M2205/15 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3337 , A61M2205/3368 , A61M2205/502 , A61M2205/52 , Y10T137/0324 , Y10T137/0379 , Y10T137/2521 , Y10T137/85978 , Y10T137/86139
摘要： Automated control mechanisms and methods for controlling fluid flow in a hemodialysis apparatus are described. The methods can involve a controller receiving information from a pressure sensor in a control chamber of a reciprocating diaphragm-based blood pump and causing the application of a time-varying pressure waveform on a diaphragm of the blood pump during a fill-stroke of the blood pump. The controller can be configured and programmed to monitor a pressure variation in the control chamber measured by the pressure sensor and to compare the measured pressure variation to a pre-determined value. Based on such comparison, the controller can initiate a procedure to pause or stop a dialysate pump of the hemodialysis apparatus if the magnitude of the measured pressure variation deviates from the pre-determined value.
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公开(公告)号：US11103625B2
公开(公告)日：2021-08-31
申请号：US15423717
申请日：2017-02-03
发明人： Michael J. Wilt
IPC分类号： A61M1/16 , A61K33/00 , A61M1/36 , A61M1/30 , A61M1/34 , A61M1/26 , A61M5/172 , A61M1/14 , G16H20/40 , A61M60/268 , A61M60/43 , A61M60/113 , A61M60/892 , A61M60/894
摘要： Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.
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公开(公告)号：US11052181B2
公开(公告)日：2021-07-06
申请号：US17067605
申请日：2020-10-09
IPC分类号： A61M1/16 , F04B43/06 , F04B43/02 , F04B43/073 , F04B45/053 , F04B53/10 , F16K99/00 , A61M60/268 , A61M1/14 , A61M60/43 , A61M60/113
摘要： A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
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公开(公告)号：US12026271B2
公开(公告)日：2024-07-02
申请号：US18103458
申请日：2023-01-30
发明人： Todd A. Ballantyne , Jon H. Cook , Benjamin E. Colburn , Andrew E. Harner , Corey Christous , Shane Whalen
IPC分类号： G06F21/62 , G05B15/02 , G06F21/00 , G06F21/50 , G06F21/51 , G06F21/55 , G06F21/56 , G06F21/57 , G16H20/17 , G16H20/40 , G16H40/40 , G16H40/60 , G16H40/63 , G16H40/67 , G16H70/40 , A61M1/16 , A61M1/34 , A61M1/36 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/43 , A61M60/50 , A61M60/515 , A61M60/538 , A61M60/892 , A61M60/894
CPC分类号： G06F21/6218 , G05B15/02 , G06F21/00 , G06F21/50 , G06F21/51 , G06F21/55 , G06F21/56 , G06F21/565 , G06F21/568 , G06F21/57 , G06F21/575 , G06F21/62 , G06F21/6227 , G06F21/6245 , G16H20/17 , G16H20/40 , G16H40/40 , G16H40/60 , G16H40/63 , G16H40/67 , G16H70/40 , A61M1/16 , A61M1/1601 , A61M1/1605 , A61M1/1613 , A61M1/1619 , A61M1/1654 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/1664 , A61M1/1692 , A61M1/34 , A61M1/3413 , A61M1/3609 , A61M1/3621 , A61M1/3627 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/43 , A61M60/50 , A61M60/515 , A61M60/538 , A61M60/892 , A61M60/894 , A61M2202/0498 , A61M2205/12 , A61M2205/15 , A61M2205/16 , A61M2205/17 , A61M2205/18 , A61M2205/3313 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/3379 , A61M2205/3393 , A61M2205/50 , A61M2205/502 , A61M2230/65 , G06F2206/1008 , G06F2221/2143
摘要： A processor of a medical device configured to communicate with a remote server can be programmed to protect the medical device from exposure to unauthorized or malicious software. A system or method to implement this form of protection can include, for example, at least one processor on the medical device, a control software module that controls the operation of the medical device and is executable on the processor, a data management module that manages data flow to and from the control software module from sources external to the medical device, and an agent module that has access to a limited number of designated memory locations in the medical device. In addition, a hemodialysis apparatus can be configured to operate in conjunction with an apparatus for providing purified water from a source such as a municipal water supply or a well. A system for controlling delivery of purified water to the hemodialysis apparatus can comprise a therapy controller of the hemodialysis apparatus configured to communicate with a controller of a water purification device, and a user interface controller of the hemodialysis apparatus configured to communicate with the therapy controller, and to send data to and receive data from a user interface.
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公开(公告)号：US12011516B2
公开(公告)日：2024-06-18
申请号：US16310638
申请日：2017-06-19
申请人： Cornell University
IPC分类号： A61L31/14 , A61F2/24 , A61L31/06 , A61L31/10 , A61M60/191 , A61M60/289 , A61M60/43 , A61M60/468 , A61M60/839 , C08J7/04 , F16F5/00
CPC分类号： A61L31/146 , A61L31/06 , A61L31/10 , A61M60/191 , A61M60/289 , A61M60/43 , A61M60/468 , A61M60/839 , C08J7/042 , F16F5/00 , A61F2/2481 , A61L2420/02 , C08J2400/26
摘要： Foam-based pneumatic actuators can be formed in a state of mechanical compression prior to actuation. An actuator includes an elastomeric foam; a coating disposed on the elastomeric foam; and an elastomer seal disposed on the coating. The coating constrains the elastomeric foam and can be configured to break or fracture when the elastomeric foam inflates. The elastomer seal can be configured to be impermeable to the actuating fluid. Such a foam actuator can be used in a cardiac compression device. These foam actuators possess increased actuation deformation and an actuation exerted force for a given inflation pressure. A large deformation can be provided from materials having low ultimate strains.
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公开(公告)号：US20230381383A1
公开(公告)日：2023-11-30
申请号：US18446323
申请日：2023-08-08
IPC分类号： A61M1/16 , A61M1/36 , A61K33/00 , A61M60/427 , A61M60/37 , A61M1/30 , A61M5/172 , A61M1/34 , G16H20/40 , A61M1/14 , A61M60/43 , A61M1/26 , A61M60/837 , A61M60/268 , A61M60/113 , A61M60/851 , A61M60/847 , A61M60/894 , A61M60/892
CPC分类号： A61M1/1601 , A61M1/1654 , A61M1/166 , A61M1/3609 , A61K33/00 , A61M60/427 , A61M60/37 , A61M1/362266 , A61M1/362227 , A61M1/362265 , A61M1/301 , A61M5/172 , A61M1/1692 , A61M1/34 , A61M1/3627 , G16H20/40 , A61M1/1668 , A61M1/1666 , A61M1/3413 , A61M1/1524 , A61M1/156 , A61M1/1605 , A61M1/1619 , A61M1/341 , A61M60/43 , A61M1/15632 , A61M1/1565 , A61M1/36224 , A61M1/36225 , A61M1/362264 , A61M1/267 , A61M1/1613 , A61M60/837 , A61M1/15625 , A61M1/154 , A61M1/3621 , A61M1/1658 , A61M1/1664 , A61M60/268 , A61M60/113 , A61M1/3672 , A61M1/36226 , A61M1/14 , A61M1/16 , A61M1/1656 , A61M60/851 , A61M60/847 , A61M1/155 , A61M2205/3317 , A61M2205/3334 , A61M2205/3584 , A61M1/362261 , A61M2205/3368 , A61M2205/3313 , A61M2205/3379 , A61M2205/3324 , A61M60/894 , Y02A90/10 , A61M2205/18 , A61M2205/50 , A61M60/892 , A61M2205/12 , A61M2205/3306 , Y02A50/30 , A61M2205/15 , A61M2205/3569 , A61M1/3638 , A61M2205/3331 , A61M2205/52 , A61M2205/502 , A61M1/1561 , A61M2230/65
摘要： Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.
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公开(公告)号：US11754064B2
公开(公告)日：2023-09-12
申请号：US17128667
申请日：2020-12-21
发明人： Brian D. Tracey , Larry B. Gray , Jason A. Demers , James D. Dale , N. Christopher Perry , Michael J. Wilt , Scott A. Leonard
IPC分类号： F04B43/073 , F04B43/00 , F04B23/06 , F04B39/12 , F04B53/22 , F04B7/02 , F04B53/16 , F04B39/14 , A61M1/16 , A61M60/851 , A61M60/427 , A61M60/268 , A61M60/847 , A61M60/837 , A61M60/849 , A61M60/113 , A61M60/37 , A61M1/28 , F04B9/109 , F04B13/02 , F04B41/06 , F04B45/02 , F04B45/053 , F04B49/02 , F04B49/22 , F04B53/06 , F04B53/10 , F17D3/00 , A61M60/894 , A61M60/43 , A61M60/892
CPC分类号： F04B43/073 , A61M1/16 , A61M1/1605 , A61M1/1639 , A61M1/1656 , A61M1/1664 , A61M1/1666 , A61M1/287 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/427 , A61M60/837 , A61M60/847 , A61M60/849 , A61M60/851 , F04B7/02 , F04B9/109 , F04B13/02 , F04B23/06 , F04B39/12 , F04B39/123 , F04B39/14 , F04B41/06 , F04B43/00 , F04B43/0081 , F04B43/0736 , F04B45/02 , F04B45/0536 , F04B49/02 , F04B49/22 , F04B53/06 , F04B53/10 , F04B53/16 , F04B53/22 , F17D3/00 , A61M60/43 , A61M60/892 , A61M60/894 , A61M2205/12 , A61M2205/128 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368 , Y10T137/0324 , Y10T137/0379 , Y10T137/2521 , Y10T137/85978 , Y10T137/86139
摘要： Described are fluid pumping and fluid handling systems, which may be suitable for use in medical devices, such as artificial or extracorporeal blood pumping systems. The systems can include a dual housing configuration for pneumatic actuation comprising a main housing containing a pump cassette comprising a pneumatically actuated pump and pneumatically actuated valves. The pump can include a pump actuation chamber and pump pneumatic port, and the valves can each include a valve actuation chamber and valve pneumatic port. Connecting tubes can be used to fluidly connect the pump actuation ports and valve actuation ports to a tube-support housing having a first side receiving one end of each connecting tube and a second side providing a pneumatic interface arranged to connect to an array of pneumatic receptacles on a base unit of the system to facilitate easy, compact and accurate pneumatic interconnection between the pump cassette and the base unit.
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