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公开(公告)号：US12097476B2
公开(公告)日：2024-09-24
申请号：US18206183
申请日：2023-06-06
发明人： Jason A. Demers , Frederick Morgan
CPC分类号： B01F33/846 , A61J1/16 , A61J1/20 , A61J3/002 , A61J3/074 , B01F33/848 , G05D11/134 , G16H40/63
摘要： A system including a containment assembly for enclosing a medication container may comprise a first housing portion or interface portion having a proximal end and a distal end. The interface portion may include a housing wall which defines a channel spanning from the proximal end to the distal end. The channel may be open at the proximal and distal end. The containment assembly may further comprise only two pierceable septa configured to form a barrier to the channel. The containment assembly may further comprise a variable-volume housing portion having a variable volume chamber. The variable-volume portion chamber of the variable-volume housing portion may be in fluid communication with the distal end of the channel.
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公开(公告)号：US20240299652A1
公开(公告)日：2024-09-12
申请号：US18665972
申请日：2024-05-16
CPC分类号： A61M5/162 , A61M5/14248 , A61M5/168 , A61M5/142 , A61M2005/14252 , A61M2005/14268 , A61M2005/14506 , A61M2005/1581 , A61M2005/1583 , A61M2005/1585 , A61M5/425 , A61M39/1011
摘要： A two-stage infusion set inserter system is disclosed. The inserter system includes an inserter assembly including a housing including a rotatable button assembly comprising ramps and and tab indents and a non-rotatable portion of housing, a sliding component comprising sliding component tabs, a needle carrier connected to an introduction needle, the needle carrier slidably movable from a starting position to an injection position and then to a second ending position, a sliding component spring, and a needle spring, wherein the rotatable button assembly rotates from a locked to an unlocked position, wherein when force is applied onto the rotatable button assembly, the sliding component and needle carrier are forced downward by the sliding component spring, and wherein when the needle carrier reaches the injection position, the needle spring forces the needle carrier upward towards the second ending position.
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公开(公告)号：US12064540B2
公开(公告)日：2024-08-20
申请号：US18452516
申请日：2023-08-18
CPC分类号： A61M1/1601 , A61M1/154 , A61M1/155 , A61M1/15625 , A61M1/1565 , A61M1/16 , A61M1/1621 , A61M1/1654 , A61M1/1694 , A61M1/267 , A61M1/3401 , A61M1/341 , A61M1/3413 , A61M1/3424 , A61M1/3609 , A61M1/3621 , A61M1/36224 , A61M1/36225 , A61M1/362263 , A61M1/362265 , A61M1/362266 , A61M1/3623 , A61M1/3638 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3672 , A61M1/1561 , A61M1/362261 , A61M2205/07 , A61M2205/12 , A61M2205/123 , A61M2205/125 , A61M2205/128 , A61M2205/15 , A61M2205/16 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/36 , A61M2205/505 , A61M2205/82 , A61M2205/8218 , A61M2205/8225 , Y10T137/87893
摘要： The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments.
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公开(公告)号：US12044229B2
公开(公告)日：2024-07-23
申请号：US18357076
申请日：2023-07-21
发明人： Brian D. Tracey , Larry B. Gray , Jason A. Demers , James D. Dale , N. Christopher Perry , Michael J. Wilt , Scott A. Leonard
IPC分类号： F04B43/073 , A61M1/16 , A61M1/28 , A61M1/36 , F04B7/02 , F04B23/06 , F04B39/12 , F04B39/14 , F04B43/00 , F04B53/16 , F04B53/22
CPC分类号： F04B43/073 , A61M1/16 , A61M1/1605 , A61M1/1656 , A61M1/287 , A61M1/362227 , A61M1/36225 , A61M1/362265 , F04B7/02 , F04B23/06 , F04B39/12 , F04B39/123 , F04B39/14 , F04B43/0081 , F04B43/0736 , F04B53/16 , F04B53/22 , A61M1/362263 , A61M2205/12 , A61M2205/128 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368
摘要： Embodiments of the present invention relate generally to certain types of reciprocating positive-displacement pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid. The pumps may be configured specifically to impart low shear forces and low turbulence on the fluid as the fluid is pumped from an inlet to an outlet. Such pumps may be particularly useful in pumping fluids that may be damaged by such shear forces (e.g., blood, and particularly heated blood, which is prone to hemolysis) or turbulence (e.g., surfactants or other fluids that may foam or otherwise be damaged or become unstable in the presence of turbulence).
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公开(公告)号：US12044228B2
公开(公告)日：2024-07-23
申请号：US18138711
申请日：2023-04-24
IPC分类号： F04B43/06 , A61M1/14 , A61M1/16 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/427 , A61M60/523 , A61M60/546 , A61M60/847 , A61M60/851 , F04B9/109 , F04B13/02 , F04B43/02 , F04B43/073 , F04B45/053 , F04B53/10 , F16K99/00 , A61M60/43
CPC分类号： F04B43/06 , A61M1/14 , A61M1/154 , A61M1/155 , A61M1/15625 , A61M1/1563 , A61M1/1565 , A61M1/16 , A61M1/1601 , A61M1/1639 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/427 , A61M60/523 , A61M60/546 , A61M60/847 , A61M60/851 , F04B9/109 , F04B13/02 , F04B43/02 , F04B43/073 , F04B43/0733 , F04B45/053 , F04B45/0536 , F04B53/106 , F04B53/1062 , F16K99/0015 , A61M1/153 , A61M60/43 , A61M2205/12 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3368 , Y10T137/0329 , Y10T137/2521 , Y10T137/2931 , Y10T137/7879 , Y10T137/85978 , Y10T137/86139
摘要： A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
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公开(公告)号：US12024701B2
公开(公告)日：2024-07-02
申请号：US17465133
申请日：2021-09-02
发明人： Christopher C. Langenfeld , David D. B. Cannan , Dirk A. van der Merwe , Dean Kamen , Jason A. Demers , Frederick Morgan , Timothy D. Moreau , Brian D. Tracey , Matthew Ware , Richard J. Lanigan , Michael A. Baker , David Blumberg, Jr. , Richard E. Gautney , Derek G. Kane , Dane Fawkes , Thomas J. Bollenbach , Michael C. Tilley , Stuart A. Jacobson , John F. Mannisto
IPC分类号： C12M3/00 , A01N1/02 , A61L27/38 , B33Y10/00 , B33Y30/00 , B33Y70/00 , C12M1/00 , C12M1/12 , C12M1/26 , C12M1/34 , C12M1/36 , C12N1/00 , C12N5/00
CPC分类号： C12M41/48 , A01N1/0247 , A61L27/3895 , B33Y10/00 , B33Y30/00 , B33Y70/00 , C12M21/08 , C12M23/22 , C12M23/38 , C12M25/02 , C12M27/18 , C12M29/00 , C12M33/00 , C12M37/02 , C12M41/12 , C12M41/40 , C12M41/46 , C12N5/0018 , C12N5/0062 , C12N2533/00 , C12N2533/50 , C12N2533/90
摘要： A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.
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公开(公告)号：US11779691B2
公开(公告)日：2023-10-10
申请号：US17107495
申请日：2020-11-30
IPC分类号： F04B7/02 , F04B53/10 , F04B43/06 , A61M1/16 , A61M1/28 , F04B9/109 , F04B13/02 , F04B23/06 , F04B41/06 , F04B43/00 , F04B43/073 , F04B45/02 , F04B45/053 , F04B49/22 , F04B53/06 , F04B53/16 , F17D3/00 , F04B49/02 , A61M60/43
CPC分类号： A61M1/1639 , A61M1/16 , A61M1/1605 , A61M1/1656 , A61M1/1664 , A61M1/1666 , A61M1/287 , F04B7/02 , F04B9/109 , F04B13/02 , F04B23/06 , F04B41/06 , F04B43/00 , F04B43/06 , F04B43/0736 , F04B45/02 , F04B45/0536 , F04B49/02 , F04B49/22 , F04B53/06 , F04B53/10 , F04B53/16 , F17D3/00 , A61M60/43 , A61M2205/12 , A61M2205/128 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368 , Y10T137/0324 , Y10T137/0379 , Y10T137/2521 , Y10T137/85978 , Y10T137/86139
摘要： A pumping cassette including a housing having at least two inlet fluid lines and at least two outlet fluid lines. At least one balancing pod within the housing and in fluid connection with the fluid paths. The balancing pod balances the flow of a first fluid and the flow of a second fluid such that the volume of the first fluid equals the volume of the second fluid. The balancing pod also includes a membrane that forms two balancing chambers. Also included in the cassette is at least two reciprocating pressure displacement membrane pumps. The pumps are within the housing and they pump the fluid from a fluid inlet to a fluid outlet line and pump the second fluid from a fluid inlet to a fluid outlet.
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公开(公告)号：US11633526B2
公开(公告)日：2023-04-25
申请号：US17366609
申请日：2021-07-02
IPC分类号： A61M1/16 , A61M1/14 , A61M60/113 , A61M60/268 , A61M60/37 , A61M60/427 , A61M60/847 , A61M60/851 , F04B9/109 , F04B13/02 , F04B43/02 , F04B43/06 , F04B43/073 , F04B45/053 , F04B53/10 , F16K99/00 , A61M60/546 , A61M60/523 , A61M60/43
摘要： A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.
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公开(公告)号：US11529444B2
公开(公告)日：2022-12-20
申请号：US16901926
申请日：2020-06-15
摘要： Dialysis systems comprising actuators that cooperate to perform dialysis functions and sensors that cooperate to monitor dialysis functions are disclosed. According to one aspect, such a hemodialysis system comprises a user interface model layer, a therapy layer, below the user interface model layer, and a machine layer below the therapy layer. The user interface model layer is configured to manage the state of a graphical user interface and receive inputs from a graphical user interface. The therapy layer is configured to run state machines that generate therapy commands based at least in part on the inputs from the graphical user interface. The machine layer is configured to provide commands for the actuators based on the therapy commands.
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公开(公告)号：US11471594B2
公开(公告)日：2022-10-18
申请号：US14323636
申请日：2014-07-03
发明人： Kevin L. Grant , Jason A. Demers , Brian D. Tracey , Dean Kamen , Richard J. Lanigan , Gregory R. Lanier, Jr. , Bright C. K. Foo , Lisa A. Panneton , Thomas F. Soldau , Stephen L. Fichera , David D. B. Cannan
摘要： A fluid connector assembly. The fluid connector assembly includes a tab portion including a slot; a plug portion slidably connected to the tab portion the plug portion comprising a fluid path and a disc, the disc configured to seat within the slot; a catch feature located on a first end of the tab portion and configured to interact with a reservoir; and a latching feature located on a second end of the tab portion, the latching feature configured to interact and lock onto the reservoir, wherein force applied to the plug portion may overcome a threshold force and unseat the disc from the slot wherein the plug portion moves with respect to the tab portion.
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