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公开(公告)号：US12131826B2
公开(公告)日：2024-10-29
申请号：US18126642
申请日：2023-03-27
发明人： Dean Kamen , Larry B. Gray , Jesse T. Bodwell , John M. Kerwin , Dirk van der Merwe , Stephen L. Fichera , Jonathan R. Thurber , Martin D. Desch
CPC分类号： G16H40/67 , A61M5/142 , A61M5/14236 , A61M5/172 , G16H20/17 , G16H40/63 , A61M2205/103 , A61M2205/16 , A61M2205/18 , A61M2205/332 , A61M2205/3331 , A61M2205/3334 , A61M2205/3365 , A61M2205/3584 , A61M2205/50 , A61M2205/505 , A61M2205/52 , A61M2205/581 , A61M2205/587 , A61M2205/6054 , A61M2205/8206
摘要： A syringe pump includes a lead screw, a motor, and a sliding block assembly. The lead screw has threads and the motor is coupled to the lead screw to rotate it. The half-nut housing has a half nut and a barrel cam. The half nut is disposed within the half-nut housing. The half nut has half-nut threads at an end adjacent to the lead screw void. The half nut engages or disengages with the threads of the lead screw. The half nut includes a half-nut cam-follower surface and a half nut slot. The barrel cam is disposed within the half-nut housing and engages with the half-nut cam-follower surface. The barrel cam includes a pin to fit within the half nut slot such that the barrel cam rotates between a first position and a second position to actuate the half nut between the engagement position and the disengagement position, respectively.
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公开(公告)号：US20240318125A1
公开(公告)日：2024-09-26
申请号：US18613621
申请日：2024-03-22
发明人： Matthew White , Kevin Kim , Bryan A. Finseth
CPC分类号： C12M41/48 , A61B10/0096 , C12M23/08 , C12M23/28 , C12M27/18 , C12M29/00 , C12M29/04 , C12M29/20 , C12M45/02 , C12M45/05 , C12M45/06
摘要： A system and method for automatically digesting, culturing and growing a biopsy. The digester is a closed fluid transfer system, including disposable and durable parts, that receives a biopsy, washes the biopsy tissue, digests the tissue to separate the cells from each other, and seeds the cells in a culture flask. In one use, the system receives cells from a patient, expands and multiplies them, and returns them to the patient. A controller coordinates the motion of a plurality of pumps and the status of a plurality of valves, the pumps and the plurality of valves moving the fluid throughout the system. A sensor system assists the controller in volume and flow rate control of the fluids in the system, and in controlling the position of a tube providing air and fluids to a biopsy vial that includes the biopsy.
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公开(公告)号：US12097476B2
公开(公告)日：2024-09-24
申请号：US18206183
申请日：2023-06-06
发明人： Jason A. Demers , Frederick Morgan
CPC分类号： B01F33/846 , A61J1/16 , A61J1/20 , A61J3/002 , A61J3/074 , B01F33/848 , G05D11/134 , G16H40/63
摘要： A system including a containment assembly for enclosing a medication container may comprise a first housing portion or interface portion having a proximal end and a distal end. The interface portion may include a housing wall which defines a channel spanning from the proximal end to the distal end. The channel may be open at the proximal and distal end. The containment assembly may further comprise only two pierceable septa configured to form a barrier to the channel. The containment assembly may further comprise a variable-volume housing portion having a variable volume chamber. The variable-volume portion chamber of the variable-volume housing portion may be in fluid communication with the distal end of the channel.
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公开(公告)号：US20240299652A1
公开(公告)日：2024-09-12
申请号：US18665972
申请日：2024-05-16
CPC分类号： A61M5/162 , A61M5/14248 , A61M5/168 , A61M5/142 , A61M2005/14252 , A61M2005/14268 , A61M2005/14506 , A61M2005/1581 , A61M2005/1583 , A61M2005/1585 , A61M5/425 , A61M39/1011
摘要： A two-stage infusion set inserter system is disclosed. The inserter system includes an inserter assembly including a housing including a rotatable button assembly comprising ramps and and tab indents and a non-rotatable portion of housing, a sliding component comprising sliding component tabs, a needle carrier connected to an introduction needle, the needle carrier slidably movable from a starting position to an injection position and then to a second ending position, a sliding component spring, and a needle spring, wherein the rotatable button assembly rotates from a locked to an unlocked position, wherein when force is applied onto the rotatable button assembly, the sliding component and needle carrier are forced downward by the sliding component spring, and wherein when the needle carrier reaches the injection position, the needle spring forces the needle carrier upward towards the second ending position.
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公开(公告)号：US12080400B2
公开(公告)日：2024-09-03
申请号：US17567272
申请日：2022-01-03
IPC分类号： A61M5/14 , A61M5/145 , A61M5/168 , A61M5/172 , G01L7/16 , G01L9/00 , G06F3/0488 , G16H10/65 , G16H20/10 , G16H20/17 , G16H40/63 , G16H40/67 , G16H70/40 , A61M5/142
CPC分类号： G16H20/17 , A61M5/1408 , A61M5/1415 , A61M5/1452 , A61M5/1456 , A61M5/1458 , A61M5/16827 , A61M5/16831 , A61M5/16859 , A61M5/172 , G01L7/16 , G01L9/00 , G01L9/0089 , G06F3/0488 , G16H10/65 , G16H20/10 , G16H40/63 , G16H40/67 , G16H70/40 , A61M5/1413 , A61M2005/14208 , A61M5/14232 , A61M5/16854 , A61M2005/16863 , A61M2005/16872 , A61M2205/12 , A61M2205/14 , A61M2205/18 , A61M2205/3306 , A61M2205/3317 , A61M2205/332 , A61M2205/3368 , A61M2205/3553 , A61M2205/3569 , A61M2205/3576 , A61M2205/3584 , A61M2205/50 , A61M2205/505 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/6063 , A61M2205/8206 , A61M2209/02 , A61M2209/082 , A61M2209/086
摘要： A syringe pump is disclosed that includes a pressure sensor assembly, a plunger, first and second pressure sensors, and a processor. The pressure sensor assembly senses a force and includes the plunger having a sensing surface configured to receive the force, the first pressure sensor operatively coupled to the plunger and configured to estimate the force applied to the sensing surface, and the second pressure sensor operatively coupled to the plunger and configured to estimate the force applied to the sensing surface. The processor is coupled to the first and second pressure sensors to estimate a magnitude of the force.
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公开(公告)号：US20240277919A1
公开(公告)日：2024-08-22
申请号：US18636455
申请日：2024-04-16
发明人： Gregory R. Lanier, JR. , Larry B. Gray , Richard J. Lanigan , Dean Kamen , Stephen L. Fichera , John M. Kerwin
IPC分类号： A61M5/142 , A61M5/145 , A61M5/168 , F04B17/00 , F04B17/06 , F04B49/00 , F04B49/06 , G05D7/06
CPC分类号： A61M5/14224 , A61M5/14248 , A61M5/14586 , A61M5/16809 , F04B17/00 , F04B17/06 , F04B49/00 , F04B49/065 , G05D7/0676 , A61M2005/14268 , A61M2205/0266 , A61M2205/0294 , A61M2205/18 , A61M2205/3306 , A61M2205/3317 , A61M2205/3327 , A61M2205/3331 , A61M2205/3375 , A61M2205/3576 , A61M2205/502 , A61M2205/52 , A61M2205/582 , A61M2205/8237 , A61M2206/22 , A61M2209/045
摘要： A wearable infusion pump assembly includes a reservoir for receiving an infusible fluid, and an external infusion set configured to deliver the infusible fluid to a user. A fluid delivery system is configured to deliver the infusible fluid from the reservoir to the external infusion set. The fluid delivery system includes a volume sensor assembly, and a pump assembly for extracting a quantity of infusible fluid from the reservoir and providing the quantity of infusible fluid to the volume sensor assembly. The volume sensor assembly is configured to determine the volume of at least a portion of the quantity of fluid. The fluid delivery system further includes at least one optical sensor assembly configured to sense the movement of the pump assembly, a first valve assembly configured to selectively isolate the pump assembly from the reservoir, and a second valve assembly configured to selectively isolate the volume sensor assembly from the external infusion set.
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公开(公告)号：US12064540B2
公开(公告)日：2024-08-20
申请号：US18452516
申请日：2023-08-18
CPC分类号： A61M1/1601 , A61M1/154 , A61M1/155 , A61M1/15625 , A61M1/1565 , A61M1/16 , A61M1/1621 , A61M1/1654 , A61M1/1694 , A61M1/267 , A61M1/3401 , A61M1/341 , A61M1/3413 , A61M1/3424 , A61M1/3609 , A61M1/3621 , A61M1/36224 , A61M1/36225 , A61M1/362263 , A61M1/362265 , A61M1/362266 , A61M1/3623 , A61M1/3638 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M1/3672 , A61M1/1561 , A61M1/362261 , A61M2205/07 , A61M2205/12 , A61M2205/123 , A61M2205/125 , A61M2205/128 , A61M2205/15 , A61M2205/16 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/36 , A61M2205/505 , A61M2205/82 , A61M2205/8218 , A61M2205/8225 , Y10T137/87893
摘要： The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments.
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公开(公告)号：US12059547B2
公开(公告)日：2024-08-13
申请号：US17333133
申请日：2021-05-28
发明人： Dean Kamen , John M. Kerwin , Colin H. Murphy
CPC分类号： A61M5/142 , A61M5/1452 , A61M5/1684 , G01F23/296 , A61M2205/18 , A61M2205/3306 , A61M2205/3375 , A61M2205/3379 , A61M2205/3592 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/6054 , A61M2205/6072 , G16H20/17 , G16H40/60
摘要： A pump includes a reservoir, a port, and a plunger. The reservoir delivers a liquid by discharging the liquid through the port coupled to the reservoir. A piston of the plunger defines a liquid side of the reservoir and a non-liquid side of the reservoir whereby movement of the plunger towards the liquid side of the reservoir discharges liquid through the port. The pump also includes a reference-volume assembly and/or a linear position sensor. The reference-volume assembly is coupled to the reservoir at an opposite end of the reservoir relative to the port and includes a reference-volume chamber in acoustic communication with the non-liquid side of the reservoir, a speaker disposed within the reference-volume chamber, and a reference microphone disposed within the reference-volume chamber. The pump estimate the amount of liquid discharged from the reservoir.
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公开(公告)号：US20240261963A1
公开(公告)日：2024-08-08
申请号：US18630031
申请日：2024-04-09
发明人： Christopher C. Langenfeld , Michael J. Slate , Prashant Bhat , Dirk A. Van Der Merwe , David D.B. Cannan , Keith D. Violette
IPC分类号： B25J9/16 , A61B17/00 , A61B34/00 , A61B34/30 , A61B46/10 , A61B90/00 , B25J9/06 , B25J9/10 , B25J9/12 , F16C1/16 , F16H25/20 , G01L1/04
CPC分类号： B25J9/1638 , A61B34/30 , A61B34/73 , A61B46/10 , B25J9/06 , B25J9/104 , B25J9/126 , B25J9/161 , B25J9/1635 , G01L1/04 , A61B2017/00477 , A61B2090/034 , A61B2090/064 , F16C1/16 , F16H25/20 , Y10S901/02 , Y10S901/19 , Y10S901/21 , Y10S901/23 , Y10S901/28
摘要： A force transmission system as part of a surgical system which may be configured to be a minimally invasive and/or computer assisted surgical system. Operation of the system may be controlled by transmission of a force from a first section to a second section of the system. The first section and the second section may be separated by a partition or a barrier. The first section may be a non-sterile section and the second section may be a sterile section of the surgical system.
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公开(公告)号：US20240261499A1
公开(公告)日：2024-08-08
申请号：US18636733
申请日：2024-04-16
发明人： Richard J. Lanigan
CPC分类号： A61M5/158 , A61M5/14248 , A61M2005/1585 , A61M2005/1586
摘要： An inserter assembly comprising a first unit including a skin contacting face which surrounds an opening and a second unit housed within the first unit. The second unit comprises an infusion set base disposed within the opening and having a bottom face which is substantially level with the skin contacting face and covered at least partially with adhesive and further comprising a spring biased insertion assembly. The second unit further comprising a cannula sub assembly carried by an insertion sharp of the insertion assembly. The spring biased insertion assembly and a cannula of the cannula sub assembly are driven into skin and the cannula sub assembly is coupled into the infusion set base by an insertion spring which is released from an energy storing state after the skin has been tugged upward beyond a certain distance by the adhesive as the inserter assembly is withdrawn from the body.
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