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公开(公告)号：US20250059330A1
公开(公告)日：2025-02-20
申请号：US18929889
申请日：2024-10-29
Applicant: Alcon Inc.
Inventor： Steve Yun Zhang , Daqing Wu , Junhao Ge , Richard Charles Breitkopf , Xinming Qian , Zach Munoz , Matthew D. Nelson , Augustine Twum Kumi , Weihong Lang , Ying Zheng , Feng Jing , Frank Chang
IPC: C08G77/442 , B29D11/00 , C08G77/12 , C08G77/14 , C08G77/20 , C08G77/388 , C08G77/392 , C08L83/10 , G02B1/04 , G02C7/04
Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.
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公开(公告)号：US12171871B2
公开(公告)日：2024-12-24
申请号：US17392448
申请日：2021-08-03
Applicant: ALCON INC.
Inventor： Junhao Ge , Steve Yun Zhang , Daqing Wu , Jing Cheng , Yuan Chang , Feng Jing , Jang-Shing Chiou , Stephen Raymond Perreault
Abstract: The present invention relates to a method to load a water insoluble phospholipid as nanoparticles to load into a hydrogel contact lens in autoclaving process during the hydrogel contact lens manufacturing process without an extra manufacturing step and without swelling the hydrogel contact lens with an organic solvent. The phospholipid nanoparticles loaded in hydrogel contact lens subsequently releases to the eye upon wearing.
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公开(公告)号：US12162987B2
公开(公告)日：2024-12-10
申请号：US18465610
申请日：2023-09-12
Applicant: Alcon Inc.
Inventor： Steve Yun Zhang , Daqing Wu , Junhao Ge , Richard Charles Breitkopf , Xinming Qian , Zach Munoz , Matthew D. Nelson , Augustine Twum Kumi , Weihong Lang , Ying Zheng , Feng Jing , Frank Chang
IPC: C08G77/442 , B29D11/00 , C08G77/12 , C08G77/14 , C08G77/20 , C08G77/388 , C08G77/392 , C08L83/10 , G02B1/04 , G02C7/04
Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.
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公开(公告)号：US11802182B2
公开(公告)日：2023-10-31
申请号：US17742559
申请日：2022-05-12
Applicant: Alcon Inc.
Inventor： Steve Yun Zhang , Daqing Wu , Junhao Ge , Richard Charles Breitkopf , Xinming Qian , Zach Munoz , Matthew D. Nelson , Augustine Twum Kumi , Weihong Lang , Ying Zheng , Feng Jing , Frank Chang
IPC: C08G77/442 , C08G77/20 , C08G77/388 , C08G77/392 , C08G77/14 , C08L83/10 , G02B1/04 , C08G77/12 , B29D11/00 , G02C7/04
CPC classification number: C08G77/442 , B29D11/00134 , C08G77/12 , C08G77/14 , C08G77/20 , C08G77/388 , C08G77/392 , C08L83/10 , G02B1/043 , G02C7/04 , C08G2210/00 , C08L2201/10 , G02B2207/109
Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.
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公开(公告)号：US20230339149A1
公开(公告)日：2023-10-26
申请号：US18306637
申请日：2023-04-25
Applicant: Alcon Inc.
Inventor： Jing Cheng , Feng Jing , Steve Yun Zhang
CPC classification number: B29C39/026 , B29C39/006 , B29C39/021 , B29C39/26 , B29C39/36 , G02B1/043 , B29K2101/10
Abstract: A method for producing embedded hydrogel contact lenses comprises at least the following steps: obtaining an insert made of a crosslinked polymeric material comprising iniferter moieties covalently attached thereto; placing the insert in a female lens mold half; dosing an amount of a lens-forming composition to immerse the insert in the female lens mold half; closing tightly a male lens mold half onto the top of the female lens mold half halves to form a molding assembly; curing the lens-forming composition in the molding assembly to form an embedded hydrogel lens precursor which comprises a bulk hydrogel material formed the lens-forming composition and the insert that is embedded therein and covalently linked to the bulk hydrogel material.
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Patent Agency Ranking
公开(公告)号：US11365288B2
公开(公告)日：2022-06-21
申请号：US17038293
申请日：2020-09-30
Applicant: Alcon Inc.
Inventor： Steve Yun Zhang , Daqing Wu , Junhao Ge , Richard Charles Breitkopf , Xinming Qian , Zach Munoz , Matthew D. Nelson , Augustine Twum Kumi , Weihong Lang , Ying Zheng , Feng Jing , Frank Chang
IPC: C08G77/442 , C08G77/20 , C08G77/388 , C08G77/392 , C08G77/14 , C08L83/10 , G02B1/04 , C08G77/12 , B29D11/00 , G02C7/04
Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.
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公开(公告)号：US20240393501A1
公开(公告)日：2024-11-28
申请号：US18670852
申请日：2024-05-22
Applicant: Alcon Inc.
Inventor： Jack W. Trieu , Daqing Wu , Feng Jing , Steve Yun Zhang
Abstract: The invention provides a method for producing coated silicone hydrogel contact lenses in a cost-effective manner. The method comprises obtaining a preformed silicone hydrogel contact lens comprising a bulk silicone hydrogel material that comprises repeating units of at least one carboxyl-containing vinylic monomer and at least one arylborono-containing vinylic monomer, and heating the preformed silicone hydrogel contact lens in an aqueous coating solution comprising a water-soluble and thermally crosslinkable polymeric material having azetidinium or epoxide groups and a diol-containing hydrophilic polymer having 1,2- or 1,3-diol moieties to form a coated silicone hydrogel contact lens comprising a bulk silicone hydrogel material and a hydrogel coating that comprises a crosslinked polymeric material covalently attached onto the bulk silicone hydrogel material and a grafted diol-containing hydrophilic polymer covalently attached onto the bulk silicone hydrogel material and distributed in the crosslinked polymeric material.
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公开(公告)号：US20240280834A1
公开(公告)日：2024-08-22
申请号：US18429551
申请日：2024-02-01
Applicant: Alcon Inc.
Inventor： Feng Jing , Steve Yun Zhang , Richard Charles Breitkopf , Claire Elizabeth Nason-Tomaszewski , Shelby Claytor
CPC classification number: G02C7/04 , C08J7/0427 , C08J2383/10 , C08J2433/14
Abstract: The invention provides an easy-to-remove water gradient contact lens. Such a water gradient contact lens comprises imperfections (ditches and/or gaps) in the anterior outer hydrogel layer and can be made according to a cost-effective method involving a step of partially or completely shielding reactive functional groups in selected zones on the anterior surface a to-be-coated contact lens before grafting a layer of a non-silicone hydrogel material. With the imperfections in the anterior outer hydrogel layer, the surface lubricity of the anterior surface is inferior to that of the posterior surface. By adjusting the shape, size, density, and rotational distribution of the imperfections, one also can selectively adjust and optimize the surface lubricity of the anterior surface of a water gradient contact lens so as to have improved lens handlability while maintaining other desirable properties.
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公开(公告)号：US11999908B2
公开(公告)日：2024-06-04
申请号：US17335628
申请日：2021-06-01
Applicant: Alcon Inc.
Inventor： Feng Jing , Frank Chang , Houliang Tang
IPC: B29D11/00 , C08F230/08 , C09K9/02 , G02B1/04 , B29K83/00 , B29K105/00
CPC classification number: C09K9/02 , B29D11/00134 , C08F230/085 , G02B1/043 , B29K2083/00 , B29K2105/0061 , C09K2211/14
Abstract: Described herein is a cost-effective and time-efficient method for producing photochromic contact lenses, in particular, preferably photochromic silicone hydrogel contact lenses, from a polymerizable composition comprising an unique selection and combination of main polymerizable components, a photochromic compound and a visible-light photoinitiator, based on the Lightstream Technology™. This invention also provides photochromic contact lenses or more preferably photochromic silicone hydrogel contact lenses made according to a method of the invention. A photochromic contact lens of the invention is capable of undergoing a reversible color change upon exposure to UV-irradiation or high-energy-violet light (HEVL) (with wavelengths from 380 nm to 440 nm).
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公开(公告)号：US11952449B2
公开(公告)日：2024-04-09
申请号：US17148197
申请日：2021-01-13
Applicant: Alcon Inc.
Inventor： Frank Chang , Feng Jing , Troy Vernon Holland , Chung-Yuan Chiang , John Dallas Pruitt
IPC: C08F226/06 , C08F220/56 , C08F220/58 , C08G73/06 , C08L33/26 , C08L79/02 , C09D5/02 , C09D133/14 , C09D133/26 , C09D179/02 , C09D179/08 , G02B1/04 , C08F220/28 , C08F220/38
CPC classification number: C08F220/56 , C08L33/26 , C08L79/02 , C09D5/02 , C09D133/14 , C09D133/26 , C09D179/02 , C09D179/08 , G02B1/043 , C08F220/283 , C08F220/286 , C08F220/382 , C08F220/58 , C08F226/06 , C08F2800/10 , C08F2810/20 , C08G73/06 , C08F220/56 , C08F220/54 , C08F220/285 , C08F220/56 , C08F220/54 , C08F220/286 , C08F220/56 , C08F220/54 , C08F220/382 , C08F220/56 , C08F220/54 , C08F220/387 , C08L33/26 , C08L79/02 , C08L33/26 , C08L79/04
Abstract: The invention is related to a class of hydrophilic poly(meth)acrylamide-based copolymers each comprising dangling (i.e., pendant) reactive chains each terminated with a carboxyl group groups and at least 50% by mole of (meth)acrylamide repeating units relative to all repeating units of the hydrophilic poly(meth)acrylamide-based copolymer. The hydrophilic copolymers have a relatively high affinity to a base coating of a polyanionic polymer on a medical device or contact lens and are highly reactive towards azetidinium groups of an azetidinium-containing polymer upon heating. They can find particular use in producing water-soluble highly-branched hydrophilic polymeric material and in producing water gradient contact lenses.
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