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公开(公告)号:US12247169B2
公开(公告)日:2025-03-11
申请号:US18645497
申请日:2024-04-25
Applicant: Alcon Inc.
Inventor: Feng Jing , Frank Chang , Houliang Tang
IPC: B29D11/00 , C08F230/08 , C09K9/02 , G02B1/04 , B29K83/00 , B29K105/00
Abstract: Described herein is a cost-effective and time-efficient method for producing photochromic contact lenses, in particular, preferably photochromic silicone hydrogel contact lenses, from a polymerizable composition comprising an unique selection and combination of main polymerizable components, a photochromic compound and a visible-light photoinitiator, based on the Lightstream Technology™. This invention also provides photochromic contact lenses or more preferably photochromic silicone hydrogel contact lenses made according to a method of the invention. A photochromic contact lens of the invention is capable of undergoing a reversible color change upon exposure to UV-irradiation or high-energy-violet light (HEVL) (with wavelengths from 380 nm to 440 nm).
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公开(公告)号:US20240392055A1
公开(公告)日:2024-11-28
申请号:US18665682
申请日:2024-05-16
Applicant: Alcon Inc.
Inventor: Troy Vernon Holland , Adam K. Sniady , Frank Chang
IPC: C08F230/08 , B29D11/00 , B29K83/00 , B29K105/00 , G02B1/04 , G02C7/10
Abstract: Described herein is a UV/HEVL-filtering SiHy contact lens that not only has a relatively high UV/HEVL filtering capability but also has an aesthetic appealing color. The bulk silicone hydrogel of the UV/HEVL-filtering SiHy contact lens comprises repeating units of (1) at least one hydrophilic vinylic monomer, (2) at least one siloxane-containing vinylic monomer and/or at least one polysiloxane vinylic crosslinker, (3) at least one UV-absorbing vinylic monomer having an absorption peak at a wavelength of from 280 nm and 380 nm, (4) a first HEVL-absorbing benzotriazole-containing vinylic monomer having an absorption peak at a wavelength of from 410 nm and 420 nm, (5) a second HEVL-absorbing benzotriazole-containing vinylic monomer having an absorption peak at a wavelength of from 415 nm and 425 nm, and (6) from about 90 ppm to about 300 ppm of repeating units of at least one polymerizable blue dye.
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公开(公告)号:US20240287379A1
公开(公告)日:2024-08-29
申请号:US18645497
申请日:2024-04-25
Applicant: Alcon Inc.
Inventor: Feng Jing , Frank Chang , Houliang Tang
IPC: C09K9/02 , B29D11/00 , B29K83/00 , B29K105/00 , C08F230/08 , G02B1/04
CPC classification number: C09K9/02 , B29D11/00134 , C08F230/085 , G02B1/043 , B29K2083/00 , B29K2105/0061 , C09K2211/14
Abstract: Described herein is a cost-effective and time-efficient method for producing photochromic contact lenses, in particular, preferably photochromic silicone hydrogel contact lenses, from a polymerizable composition comprising an unique selection and combination of main polymerizable components, a photochromic compound and a visible-light photoinitiator, based on the Lightstream Technology™. This invention also provides photochromic contact lenses or more preferably photochromic silicone hydrogel contact lenses made according to a method of the invention. A photochromic contact lens of the invention is capable of undergoing a reversible color change upon exposure to UV-irradiation or high-energy-violet light (HEVL) (with wavelengths from 380 nm to 440 nm).
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公开(公告)号:US11926689B2
公开(公告)日:2024-03-12
申请号:US17870329
申请日:2022-07-21
Applicant: Alcon Inc.
Inventor: Jinyu Huang , Frank Chang , Steve Yun Zhang , Feng Jing
IPC: C08L101/14 , C08F290/06 , C08G77/16 , C08G77/20 , C08G77/392 , C08L83/04 , G02B1/04 , C08G77/12
CPC classification number: C08F290/068 , C08G77/16 , C08G77/20 , C08G77/392 , G02B1/043 , C08G77/12 , G02B1/043 , C08L83/04 , G02B1/043 , C08L101/14
Abstract: The invention provides a hydrophilized polydiorganosiloxane vinylic crosslinker which comprises (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and hydrophilized siloxane units each having one methyl substituent and one monovalent C4-C40 organic radical substituent having two to six hydroxyl groups, wherein the molar ratio of the hydrophilized siloxane units to the dimethylsiloxane units is from about 0.035 to about 0.15, and (2) two terminal (meth)acryloyl groups. The hydrophilized polydiorganosiloxane vinylic crosslinker has a number average molecular weight of from about 3000 Daltons to about 80,000 Daltons. The present invention is also related to a silicone hydrogel contact lens, which comprises repeating units derived from a hydrophilized polydiorganosiloxane vinylic crosslinker of the invention.
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公开(公告)号:US20240018309A1
公开(公告)日:2024-01-18
申请号:US18465610
申请日:2023-09-12
Applicant: Alcon Inc.
Inventor: Steve Yun Zhang , Daqing Wu , Junhao Ge , Richard Charles Breitkopf , Xinming Qian , Zach Munoz , Matthew D. Nelson , Augustine Twum Kumi , Weihong Lang , Ying Zheng , Feng Jing , Frank Chang
IPC: C08G77/442 , C08G77/20 , C08G77/388 , C08G77/392 , C08G77/14 , C08L83/10 , G02B1/04 , C08G77/12 , B29D11/00 , G02C7/04
CPC classification number: C08G77/442 , C08G77/20 , C08G77/388 , C08G77/392 , C08G77/14 , C08L83/10 , C08L2201/10 , C08G77/12 , B29D11/00134 , G02C7/04 , G02B2207/109 , C08G2210/00 , G02B1/043
Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.
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公开(公告)号:US20230374306A1
公开(公告)日:2023-11-23
申请号:US18321435
申请日:2023-05-22
Applicant: Alcon Inc.
Inventor: Frank Chang , Troy Vernon Holland , Adam K. Sniady , Houliang Tang
CPC classification number: C08L83/04 , C08J3/075 , C08J2383/04 , C08J2471/02
Abstract: Described herein is UV/HEVL-absorbing contact lens of the invention comprises a bulk hydrogel material that comprises repeating units of at least one UV-absorbing vinylic monomer, repeating units of at least one UV/HEVL-absorbing vinylic monomer, and derivatives of a reactive Cu(II)-porphyrin present in selected amounts and at a selected ratio. A UV/HEVL-filtering contact lens of the invention not only can provide Class I UV protection against UVA and UVB rays (i.e., filtering more than 90% of UVA and 99% of UVB rays) but also can mimics the natural crystalline lens of a human eye in providing HEVL protection.
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公开(公告)号:US20230364832A1
公开(公告)日:2023-11-16
申请号:US18308210
申请日:2023-04-27
Applicant: Alcon Inc.
Inventor: Frank Chang , Troy Vernon Holland , Houliang Tang , Adam K. Sniady
CPC classification number: B29C39/026 , B29C39/006 , B29C39/26 , B29C39/36 , B29D11/00038 , G02B1/043 , B29K2101/10
Abstract: Described herein is a cost-effective and time-efficient method for producing UV- and HEVL-absorbing silicone hydrogel contact lenses capable of blocking ultra-violet (“UV”) radiation and high-energy-violet light (HEVL) with wavelengths from 380 nm to 440 nm, thereby protecting eyes to some extent from damages caused by UV and HEVL radiation. This invention also provides UV- and HEVL-absorbing absorbing contact lenses made according to a method of the invention.
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公开(公告)号:US10829574B2
公开(公告)日:2020-11-10
申请号:US16807844
申请日:2020-03-03
Applicant: Alcon Inc.
Inventor: Frank Chang , Troy Vernon Holland , Feng Jing , Ryan DeSousa
IPC: C08F28/02 , G02B1/04 , C08F8/34 , C08F8/48 , C08F8/30 , C08B37/00 , C08F24/00 , C08F26/06 , C08F20/56 , G02C7/04
Abstract: The invention is related to a class of hydrophilic copolymers comprising loosely dangling thiol-containing pendant groups. The hydrophilic copolymers are highly reactive towards azetidinium groups of an azetidinium-containing polymer upon heating and can find particular use in for producing water-soluble highly-branched hydrophilic polymeric material useful for producing water gradient contact lenses.
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公开(公告)号:US12297323B2
公开(公告)日:2025-05-13
申请号:US17700734
申请日:2022-03-22
Applicant: Alcon Inc.
Inventor: Frank Chang , Thomas M. Moy , Adam K. Sniady
IPC: C08G77/442 , C08G77/20 , C08G77/60 , G02B1/04 , C08G77/00
Abstract: The invention provides a class of high RI polysiloxane vinylic crosslinkers. Each of the polysiloxane vinylic crosslinkers of the invention comprise (1) a polysiloxane segment comprising dimethylsiloxane units and aryl-containing siloxane units each having one methyl substituent and one organic substituent having up to 45 carbon atoms and at least one aryl moiety which is linked to Si atom through a linker having at least 2 (preferably 3) carbon atoms; (2) ethylenically-unsaturated groups. The invention also provides an insert or silicone hydrogel contact lens which comprises a crosslinked polymeric material comprising repeating units of at least one of such a class of high RI polysiloxane vinylic crosslinkers.
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公开(公告)号:US11999908B2
公开(公告)日:2024-06-04
申请号:US17335628
申请日:2021-06-01
Applicant: Alcon Inc.
Inventor: Feng Jing , Frank Chang , Houliang Tang
IPC: B29D11/00 , C08F230/08 , C09K9/02 , G02B1/04 , B29K83/00 , B29K105/00
CPC classification number: C09K9/02 , B29D11/00134 , C08F230/085 , G02B1/043 , B29K2083/00 , B29K2105/0061 , C09K2211/14
Abstract: Described herein is a cost-effective and time-efficient method for producing photochromic contact lenses, in particular, preferably photochromic silicone hydrogel contact lenses, from a polymerizable composition comprising an unique selection and combination of main polymerizable components, a photochromic compound and a visible-light photoinitiator, based on the Lightstream Technology™. This invention also provides photochromic contact lenses or more preferably photochromic silicone hydrogel contact lenses made according to a method of the invention. A photochromic contact lens of the invention is capable of undergoing a reversible color change upon exposure to UV-irradiation or high-energy-violet light (HEVL) (with wavelengths from 380 nm to 440 nm).
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