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    METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES
    1.
    发明申请
    METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES 有权

    公开(公告)号：US20240399627A1

    公开(公告)日：2024-12-05

    申请号：US18678872

    申请日：2024-05-30

    Applicant: Alcon Inc.

    Inventor： Ya-Wen Chang ,  Newton T. Samuel ,  Steve Yun Zhang ,  Feng Jing

    IPC: B29C39/02 ,  B29C33/42 ,  B29C33/56 ,  B29C39/00 ,  B29C39/10 ,  B29C39/26 ,  B29D11/00 ,  B29K83/00 ,  B29K105/00 ,  B29K105/24 ,  B29L11/00

    Abstract: The invention provides a method for producing embedded contact lenses involving steps of use of a set of 3 mold halves in two-curing steps. One of the 3 mold halves have been used twice, the first time for molding an insert and the second time for molding the embedded hydrogel contact lens. The twice-used mold half has been treated with a corona plasma or a vacuum UV in a central circular area of its molding surface having a diameter equal to or smaller than the diameter of the insert to ensure that the molded insert consistently adhered to the twice-used mold half. The method also comprises a step of forming a reactive polysiloxane coating that is covalently attached onto the back or front surface of a molded insert adhered on the twice-used mold half before molding the embedded contact lens in the 2nd curing step.

    Method for making photochromic contact lenses
    4.
    发明授权
    Method for making photochromic contact lenses 有权

    公开(公告)号：US12247169B2

    公开(公告)日：2025-03-11

    申请号：US18645497

    申请日：2024-04-25

    Applicant: Alcon Inc.

    Inventor： Feng Jing ,  Frank Chang ,  Houliang Tang

    IPC: B29D11/00 ,  C08F230/08 ,  C09K9/02 ,  G02B1/04 ,  B29K83/00 ,  B29K105/00

    Abstract: Described herein is a cost-effective and time-efficient method for producing photochromic contact lenses, in particular, preferably photochromic silicone hydrogel contact lenses, from a polymerizable composition comprising an unique selection and combination of main polymerizable components, a photochromic compound and a visible-light photoinitiator, based on the Lightstream Technology™. This invention also provides photochromic contact lenses or more preferably photochromic silicone hydrogel contact lenses made according to a method of the invention. A photochromic contact lens of the invention is capable of undergoing a reversible color change upon exposure to UV-irradiation or high-energy-violet light (HEVL) (with wavelengths from 380 nm to 440 nm).

    METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES
    8.
    发明公开
    METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES 审中-公开

    公开(公告)号：US20230350100A1

    公开(公告)日：2023-11-02

    申请号：US18308189

    申请日：2023-04-27

    Applicant: Alcon Inc.

    Inventor： Lisa Nicole Hutfluss ,  Jing Cheng ,  Feng Jing ,  Steve Yun Zhang ,  Michelle Plavnik

    IPC: G02B1/04 ,  B29D11/00

    CPC classification number: G02B1/043 ,  B29D11/00134 ,  B29D11/00192 ,  B29K2083/00

    Abstract: The invention provides a method for making silicone hydrogel contact lenses in a relatively efficient and consistent manner from a lens formulation (i.e., a polymerizable composition) including a thermal initiator having a 10-hour half-life temperature (T10hλ) under a controlled thermal curing scheme. A method of the invention comprises a step of curing the lens formulation in an oven according to a thermal curing profile that comprises or consists essentially of increasing the oven's temperature from room temperature or a temperature that is at least about 5° C. lower than T10hλ to a temperature that is at least 30° C. higher than T10hλ at a selected rate (e.g., from about 1° C./minute to about 10° C./minute). Under such a controlled thermal curing scheme, the lens diameter of the fully-hydrated silicone hydrogel contact lenses obtained according to a method of the invention does not vary significantly with the positions of the molds in the oven.

    Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof
    10.
    发明授权
    Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof 有权

    公开(公告)号：US12286501B2

    公开(公告)日：2025-04-29

    申请号：US18435562

    申请日：2024-02-07

    Applicant: Alcon Inc.

    Inventor： Jinyu Huang ,  Frank Chang ,  Steve Yun Zhang ,  Feng Jing

    IPC: C08L101/14 ,  C08F290/06 ,  C08G77/16 ,  C08G77/20 ,  C08G77/392 ,  C08L83/04 ,  G02B1/04 ,  C08G77/12

    Abstract: The invention provides a hydrophilized polydiorganosiloxane vinylic crosslinker which comprises (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and hydrophilized siloxane units each having one methyl substituent and one monovalent C4-C40 organic radical substituent having two to six hydroxyl groups, wherein the molar ratio of the hydrophilized siloxane units to the dimethylsiloxane units is from about 0.035 to about 0.15, and (2) two terminal (meth)acryloyl groups. The hydrophilized polydiorganosiloxane vinylic crosslinker has a number average molecular weight of from about 3000 Daltons to about 80,000 Daltons. The present invention is also related to a silicone hydrogel contact lens, which comprises repeating units derived from a hydrophilized polydiorganosiloxane vinylic crosslinker of the invention.

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