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公开(公告)号：US12174462B2
公开(公告)日：2024-12-24
申请号：US17644838
申请日：2021-12-17
Applicant: Alcon Inc.
Inventor： Robert Carey Tucker , John Dallas Pruitt
Abstract: The invention is directed to a cosmetic functional contact lens having a pupil section, a generally annular iris section surrounding the pupil section for detecting at least one target analyte or physical attribute, comprising: a substrate for supporting electronic components and providing structural support for the functional contact lens; at least one sensing element disposed on the substrate for sensing the at least one target analyte or physical attribute and undergoing a physical change representing a sensed signal; an antenna disposed on the substrate for transmitting the sensed signal to an external device, the antenna being coupled to the at least one sensing element; a colored, printed, opaque, intermittent cosmetic pattern to mask the embedded electronic components.
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公开(公告)号：US20240176047A1
公开(公告)日：2024-05-30
申请号：US18436094
申请日：2024-02-08
Applicant: Alcon Inc.
Inventor： Yongxing Qiu , John Dallas Pruitt , Newton T. Samuel , Chung-Yuan Chiang , Robert Carey Tucker , Yuan Chang , Ethan Leveillee
IPC: G02B1/04 , B05D1/18 , B05D1/38 , B05D3/00 , B05D3/02 , B05D5/00 , B05D5/10 , B29D11/00 , B29K83/00 , B29K105/00 , B65B55/22 , C08L33/02 , C08L79/04 , C08L83/04 , C09D133/02 , G02B1/18 , G02C7/04
CPC classification number: G02B1/043 , B05D5/00 , B29D11/00038 , B29D11/00125 , B29D11/00865 , B65B55/22 , C08L33/02 , C08L79/04 , C08L83/04 , C09D133/02 , G02B1/18 , G02C7/049 , B05D1/18 , B05D1/38 , B05D3/002 , B05D3/02 , B05D5/10 , B29K2083/00 , B29K2105/0061 , C08L2201/10 , C08L2201/54 , G02B2207/109
Abstract: The invention is related to contact lenses that not only comprise the much desired water gradient structural configurations, but also have a minimized uptakes of polycationic antimicrobials and a long-lasting surface hydrophilicity and wettability even after going through a 30-days lens care regime. Because of the water gradient structural configuration and a relatively-thick, extremely-soft and water-rich hydrogel surface layer, a contact lens of the invention can provide superior wearing comfort. Further, a contact lens of the invention is compatible with multipurpose lens care solutions present in the market and can endure the harsh lens care handling conditions (e.g., digital rubbings, accidental inversion of contact lenses, etc.) encountered in a daily lens care regime. As such, they are suitable to be used as weekly- or monthly-disposable water gradient contact lenses.
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公开(公告)号：US20230158760A1
公开(公告)日：2023-05-25
申请号：US17991174
申请日：2022-11-21
Applicant: Alcon Inc.
Inventor： Yongxing Qiu , Newton T. Samuel , John Dallas Pruitt , Chandana Kolluru , Arturo Norberto Medina , Lynn Cook Winterton , Daqing Wu , Xinming Qian , Jared Nelson
IPC: B29D11/00 , G02B1/04 , G02C7/04 , G02B1/10 , G02B1/18 , C08J7/04 , C08L83/04 , C08G77/388 , C08J5/00 , C09D5/16 , C09D133/02 , C09D133/14 , C09D133/26 , C09D171/02 , C09D177/06
CPC classification number: B29D11/00067 , C08G77/388 , C08J5/00 , C08J7/042 , C08L83/04 , C09D5/1637 , C09D5/1681 , C09D133/02 , C09D133/14 , C09D133/26 , C09D171/02 , C09D177/06 , G02B1/10 , G02B1/18 , G02B1/043 , G02C7/049 , C08J2383/04 , C08J2383/08 , C08J2433/02 , C08J2433/26 , C08J2487/00 , G02C2202/06 , G02C2202/16
Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a watersoluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.
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公开(公告)号：US20220197056A1
公开(公告)日：2022-06-23
申请号：US17644838
申请日：2021-12-17
Applicant: Alcon Inc.
Inventor： Robert Carey Tucker , John Dallas Pruitt
Abstract: The invention is directed to a cosmetic functional contact lens having a pupil section, a generally annular iris section surrounding the pupil section for detecting at least one target analyte or physical attribute, comprising: a substrate for supporting electronic components and providing structural support for the functional contact lens; at least one sensing element disposed on the substrate for sensing the at least one target analyte or physical attribute and undergoing a physical change representing a sensed signal; an antenna disposed on the substrate for transmitting the sensed signal to an external device, the antenna being coupled to the at least one sensing element; a colored, printed, opaque, intermittent cosmetic pattern to mask the embedded electronic components.
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公开(公告)号：US20200339836A1
公开(公告)日：2020-10-29
申请号：US16925060
申请日：2020-07-09
Applicant: Alcon Inc.
Inventor： Yongxing Qiu , John Dallas Pruitt , Sibichen J. Thekveli , Robert Carey Tucker , Jared Nelson
IPC: C09D177/06 , B29D11/00 , G02B1/04 , G02C7/04 , G02B1/10 , G02B1/18 , C08J7/04 , C08L83/04 , C08G77/388 , C08J5/00 , C09D5/16 , C09D133/02 , C09D133/14 , C09D133/26 , C09D171/02
Abstract: The invention is related to a hydrated silicone hydrogel contact lens having a layered structural configuration: a lower water content silicone hydrogel core (or bulk material) completely covered with a layer of a higher water content hydrogel totally or substantially free of silicone. A hydrated silicone hydrogel contact lens of the invention possesses high oxygen permeability for maintaining the corneal health and a soft, water-rich, lubricious surface for wearing comfort.
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Patent Agency Ranking
公开(公告)号：US11952449B2
公开(公告)日：2024-04-09
申请号：US17148197
申请日：2021-01-13
Applicant: Alcon Inc.
Inventor： Frank Chang , Feng Jing , Troy Vernon Holland , Chung-Yuan Chiang , John Dallas Pruitt
IPC: C08F226/06 , C08F220/56 , C08F220/58 , C08G73/06 , C08L33/26 , C08L79/02 , C09D5/02 , C09D133/14 , C09D133/26 , C09D179/02 , C09D179/08 , G02B1/04 , C08F220/28 , C08F220/38
CPC classification number: C08F220/56 , C08L33/26 , C08L79/02 , C09D5/02 , C09D133/14 , C09D133/26 , C09D179/02 , C09D179/08 , G02B1/043 , C08F220/283 , C08F220/286 , C08F220/382 , C08F220/58 , C08F226/06 , C08F2800/10 , C08F2810/20 , C08G73/06 , C08F220/56 , C08F220/54 , C08F220/285 , C08F220/56 , C08F220/54 , C08F220/286 , C08F220/56 , C08F220/54 , C08F220/382 , C08F220/56 , C08F220/54 , C08F220/387 , C08L33/26 , C08L79/02 , C08L33/26 , C08L79/04
Abstract: The invention is related to a class of hydrophilic poly(meth)acrylamide-based copolymers each comprising dangling (i.e., pendant) reactive chains each terminated with a carboxyl group groups and at least 50% by mole of (meth)acrylamide repeating units relative to all repeating units of the hydrophilic poly(meth)acrylamide-based copolymer. The hydrophilic copolymers have a relatively high affinity to a base coating of a polyanionic polymer on a medical device or contact lens and are highly reactive towards azetidinium groups of an azetidinium-containing polymer upon heating. They can find particular use in producing water-soluble highly-branched hydrophilic polymeric material and in producing water gradient contact lenses.
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公开(公告)号：US11364695B2
公开(公告)日：2022-06-21
申请号：US16925060
申请日：2020-07-09
Applicant: Alcon Inc.
Inventor： Yongxing Qiu , John Dallas Pruitt , Sibichen J. Thekveli , Robert Carey Tucker , Jared Nelson
IPC: B29D11/00 , G02C7/04 , G02B1/04 , G02B1/10 , G02B1/18 , C08J7/04 , C08L83/04 , C08G77/388 , C08J5/00 , C09D5/16 , C09D133/02 , C09D133/14 , C09D133/26 , C09D171/02 , C09D177/06
Abstract: The invention is related to a hydrated silicone hydrogel contact lens having a layered structural configuration: a lower water content silicone hydrogel core (or bulk material) completely covered with a layer of a higher water content hydrogel totally or substantially free of silicone. A hydrated silicone hydrogel contact lens of the invention possesses high oxygen permeability for maintaining the corneal health and a soft, water-rich, lubricious surface for wearing comfort.
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公开(公告)号：US20210130644A1
公开(公告)日：2021-05-06
申请号：US17148197
申请日：2021-01-13
Applicant: Alcon Inc.
Inventor： Frank Chang , Feng Jing , Troy Vernon Holland , Chung-Yuan Chiang , John Dallas Pruitt
IPC: C09D133/26 , C08L33/26 , C08L79/02 , C09D179/02 , C08F220/28 , C08F220/38 , C08F220/56 , C09D5/02 , C09D133/14 , C09D179/08 , G02B1/04
Abstract: The invention is related to a class of hydrophilic poly(meth)acrylamide-based copolymers each comprising dangling (i.e., pendant) reactive chains each terminated with a carboxyl group groups and at least 50% by mole of (meth)acrylamide repeating units relative to all repeating units of the hydrophilic poly(meth)acrylamide-based copolymer. The hydrophilic copolymers have a relatively high affinity to a base coating of a polyanionic polymer on a medical device or contact lens and are highly reactive towards azetidinium groups of an azetidinium-containing polymer upon heating. They can find particular use in producing water-soluble highly-branched hydrophilic polymeric material and in producing water gradient contact lenses.
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公开(公告)号：US20200324314A1
公开(公告)日：2020-10-15
申请号：US16843989
申请日：2020-04-09
Applicant: Alcon Inc.
Inventor： Newton T. Samuel , Yongxing Qiu , John Dallas Pruitt , Matthew McCollum
IPC: B05D1/18 , G02B1/18 , C09D5/00 , C09D133/02
Abstract: The invention is generally related to a method for producing, in a consistent manner, contact lenses each having an intact durable coating thereon, wherein the coating is a hydrogel coating formed by covalently attached a hydrophilic polymeric material having azetidinium groups onto a base coating of a polyanionic polymer on a contact lens at a relatively low temperature (e.g., from about 40° C. to about 60° C.). The coating temperature for forming a durable hydrogel coating on top of the base coating of a contact lens can be significantly lowered by raising, in situ, the pH (to about 9.5 or higher) of a reactive coating solution which contains the hydrophilic polymeric material having azetidinium groups.
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公开(公告)号：US12270968B2
公开(公告)日：2025-04-08
申请号：US18436094
申请日：2024-02-08
Applicant: Alcon Inc.
Inventor： Yongxing Qiu , John Dallas Pruitt , Newton T. Samuel , Chung-Yuan Chiang , Robert Carey Tucker , Yuan Chang , Ethan Leveillee
IPC: G02B1/04 , B05D5/00 , B29D11/00 , B29K105/00 , B65B55/22 , C08L33/02 , C08L79/04 , C08L83/04 , C09D133/02 , G02B1/18 , G02C7/04 , B05D1/18 , B05D1/38 , B05D3/00 , B05D3/02 , B05D5/10 , B29K83/00
Abstract: The invention is related to contact lenses that not only comprise the much desired water gradient structural configurations, but also have a minimized uptakes of polycationic antimicrobials and a long-lasting surface hydrophilicity and wettability even after going through a 30-days lens care regime. Because of the water gradient structural configuration and a relatively-thick, extremely-soft and water-rich hydrogel surface layer, a contact lens of the invention can provide superior wearing comfort. Further, a contact lens of the invention is compatible with multipurpose lens care solutions present in the market and can endure the harsh lens care handling conditions (e.g., digital rubbings, accidental inversion of contact lenses, etc.) encountered in a daily lens care regime. As such, they are suitable to be used as weekly- or monthly-disposable water gradient contact lenses.
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