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公开(公告)号：US20240254468A1
公开(公告)日：2024-08-01
申请号：US18587167
申请日：2024-02-26
发明人： Trisha Barrett , Aaron Argyros
CPC分类号： C12N9/2402 , C12N1/18 , C12N9/1051 , C12N9/2405 , C12N9/48 , C12P7/10 , C12Y204/01001 , C12Y302/01028
摘要： The present disclosure concerns a recombinant yeast host cell exhibiting higher stability and, in some embodiments, higher fermentation performance. The recombinant yeast host cell stability has a limited ability to express an hydrolase during its propagation phase. In return, this limits the cleavage of a yeast cellular component during or after propagation which may be detrimental to the stability and/or fermentation performances. The recombinant yeast host cell expresses a heterologous hydrolase under the control of a heterologous promoter (for limiting the expression of the heterologous hydrolase during propagation and favoring the expression of the heterologous hydrolase during fermentation).
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2.发明申请公开(公告)号：US20190239553A1
公开(公告)日：2019-08-08
申请号：US16368429
申请日：2019-03-28
申请人： Jiangnan University
IPC分类号： A23P10/30 , A23L33/105 , A23L33/12 , C12P19/04 , C12P19/18
CPC分类号： A23P10/30 , A23L33/105 , A23L33/12 , A23V2002/00 , A23V2200/224 , A23V2200/30 , A23V2250/1872 , A23V2250/5118 , C12P19/04 , C12P19/18 , C12Y204/01001
摘要： The present invention discloses a glucan-based shell-core structure carrier material and preparation and application thereof, and belongs to the technical field of modern food processing. Spherical hyperbranched water-soluble amylum grains are used as the raw material, and an enzymatic grafting and chain extending process is adopted for treatment to modify the surfaces of water-soluble glucan molecules into a firm shell structure with densely cumulated crystal structures, and form the glucan-based carrying material with the shell-core structure of which an inner core cavity has an amorphous state and an outer shell layer has a crystalline state. The adopted spherical hyperbranched water-soluble amylum grains have wide sources of raw materials and are not limited by producing areas and seasons; the preparation has simple and convenient steps, easy operation, controllable reaction conditions, relatively low cost and basically no pollution to the environment; and the prepared product can effectively protect, deliver and release functional nutritional components, can be applied to multiple fields of food, medicine, chemicals for daily use and the like, and has great market prospects and broad economic benefits.
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3.发明申请公开(公告)号：US20170204394A1
公开(公告)日：2017-07-20
申请号：US15327616
申请日：2015-05-29
申请人： BRASKEM S.A.
CPC分类号： C12N9/90 , C12N9/1048 , C12N9/1051 , C12N9/12 , C12P5/007 , C12P7/06 , C12P19/32 , C12Y204/01001 , C12Y504/02002 , Y02E50/17
摘要： The present disclosure generally relates to modified microorganisms comprising an optimized system for oligosaccharide utilization comprising one or more polynucleotides coding for one or more energy independent oligosaccharide transporters for transporting an oligosaccharide into the microorganism, one or more polynucleotides coding for enzymes that catalyze the conversion of the oligosaccharide into at least one phosphorylated saccharide, and one or more polynucleotides coding for enzymes that catalyze the conversion of the phosphorylated saccharide into an isomer of the phosphorylated saccharide that is utilized in one or more enzymatic pathways in the microorganism for the production of an organic molecule such as acetic acid, acrylic acid, 3-hydroxypropionic acid, lactic acid, etc. The present disclosure also generally relates to methods of using the optimized system for oligosaccharide utilization.
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4.发明申请GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME 有权含葡萄糖的葡萄糖，其生产方法及其用途公开(公告)号：US20120135063A1
公开(公告)日：2012-05-31
申请号：US13318958
申请日：2010-05-10
申请人： Junichi Kadokawa , Takeshi Takaha , Akiko Kubo , Michiyo Yanase , Kayo Hosoya
发明人： Junichi Kadokawa , Takeshi Takaha , Akiko Kubo , Michiyo Yanase , Kayo Hosoya
IPC分类号： A61K9/127 , C08B31/00 , C08B35/00 , C07H3/06 , C12P19/04 , A61K38/02 , A61K39/395 , A61K31/711 , A61K31/7105 , A61K31/713 , C08B37/00 , A61K47/36 , B82Y5/00
CPC分类号： A61K47/36 , A61K49/0002 , C08B37/0009 , C12N9/1051 , C12P19/04 , C12Y204/01001
摘要： An object of the present invention is to provide a uronic acid-containing glucan or a modified product thereof. The glucuronic acid-containing glucan of the present invention is a glucuronic acid-containing glucan in which a glucuronic acid residue is bound to at least one non-reducing end of a glucan, and the glucan is a branched α-1,4 glucan or a linear α-1,4 glucan. The glucuronic acid-containing glucan of the present invention can be provided by allowing α-glucan phosphorylase derived from Aquifex aeolicus VF5 to act on glucuronic acid-1-phosphate to thereby transfer a glucuronic acid residue to the non-reducing end of the receptor glucan.
摘要翻译： 本发明的目的是提供一种含糖醛酸的葡聚糖或其改性产物。 本发明的含葡萄糖醛酸的葡聚糖是葡萄糖醛酸的葡聚糖，其中葡萄糖醛酸残基与葡聚糖的至少一个非还原性末端结合，葡聚糖是支链α-1,4葡聚糖或 线性α-1,4葡聚糖。 本发明的含葡萄糖醛酸的葡聚糖可以通过使来自Aquifex aeolicus VF5的α-葡聚糖磷酸化酶作用于葡萄糖醛酸-1-磷酸酯，从而将葡萄糖醛酸残基转移到受体葡聚糖的非还原末端来提供 。
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公开(公告)号：US20240352440A1
公开(公告)日：2024-10-24
申请号：US18641530
申请日：2024-04-22
申请人： BONUMOSE, INC.
CPC分类号： C12N9/90 , C12N9/1051 , C12N9/16 , C12N9/92 , C12P19/02 , C12P19/14 , C12P19/18 , C12P19/24 , C12Y204/01001 , C12Y301/03011 , C12Y503/01009 , C12Y504/02002
摘要： Disclosed herein are methods of producing hexoses from saccharides by enzymatic processes. The methods utilize fructose 6-phosphate and at least one enzymatic step to convert it to a hexose.
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公开(公告)号：US20230193232A1
公开(公告)日：2023-06-22
申请号：US18049055
申请日：2022-10-24
发明人： Trisha Barrett , Aaron Argyros
CPC分类号： C12N9/2402 , C12N1/18 , C12N9/48 , C12N9/1051 , C12N9/2405 , C12P7/10 , C12Y204/01001 , C12Y302/01028
摘要： The present disclosure concerns a recombinant yeast host cell exhibiting higher stability and, in some embodiments, higher fermentation performance. The recombinant yeast host cell stability has a limited ability to express an hydrolase during its propagation phase. In return, this limits the cleavage of a yeast cellular component during or after propagation which may be detrimental to the stability and/or fermentation performances. The recombinant yeast host cell expresses a heterologous hydrolase under the control of a heterologous promoter (for limiting the expression of the heterologous hydrolase during propagation and favoring the expression of the heterologous hydrolase during fermentation).
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7.发明申请NON-REDUCING END MODIFIED GLUCAN, METHOD FOR PRODUCING SAME, AND USE THEREOF 审中-公开非还原性末端改性葡萄糖，其生产方法及其用途公开(公告)号：US20130295163A1
公开(公告)日：2013-11-07
申请号：US13883508
申请日：2011-11-07
申请人： Takeshi Takaha , Michiyo Yanase , Akiko Kubo , Haruyo Sambe , Ryo Kakutani
发明人： Takeshi Takaha , Michiyo Yanase , Akiko Kubo , Haruyo Sambe , Ryo Kakutani
IPC分类号： C08B37/00
CPC分类号： C08B37/0009 , A61K9/5161 , A61K47/36 , A61K47/61 , A61K2039/55583 , C08B37/0063 , C12P19/04 , C12P19/28 , C12Y204/01001
摘要： An object of the present invention is to provide a glucan containing at least one residue selected from an N-acetylglucosamine residue and a galactose residue, and a modified product. The branched glucan of the present invention is a branched glucan wherein the branched glucan has a plurality of non-reducing ends and at least one residue selected from an N-acetylglucosamine residue and a galactose residue is bound via an α-1,4-bond to each of two or more non-reducing ends of the branched α-1,4-glucan, but neither an N-acetylglucosamine residue nor a galactose residue is present at the position other than the non-reducing ends of the branched α-1,4-glucan.
摘要翻译： 本发明的目的是提供一种含有至少一种选自N-乙酰氨基葡萄糖残基和半乳糖残基的残基的葡聚糖和一种改性产物。 本发明的支链葡聚糖是支链葡聚糖，其中支链葡聚糖具有多个非还原性末端，并且至少一个选自N-乙酰葡糖胺残基和半乳糖残基的残基通过α-1,4-键结合 至支链α-1,4-葡聚糖的两个或更多个非还原性末端中的每一个，但在支链α-1,4-葡聚糖的非还原末端以外的位置上不存在N-乙酰氨基葡萄糖残基和半乳糖残基 ，4-葡聚糖。
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8.发明授权Glucuronic acid-containing glucan, process for production of same, and use of same 有权含有葡萄糖醛酸的葡聚糖，其制造方法及其用途公开(公告)号：US08575131B2
公开(公告)日：2013-11-05
申请号：US13318958
申请日：2010-05-10
申请人： Junichi Kadokawa , Takeshi Takaha , Akiko Kubo , Michiyo Yanase , Kayo Hosoya
发明人： Junichi Kadokawa , Takeshi Takaha , Akiko Kubo , Michiyo Yanase , Kayo Hosoya
CPC分类号： A61K47/36 , A61K49/0002 , C08B37/0009 , C12N9/1051 , C12P19/04 , C12Y204/01001
摘要： An object of the present invention is to provide a uronic acid-containing glucan or a modified product thereof. The glucuronic acid-containing glucan of the present invention is a glucuronic acid-containing glucan in which a glucuronic acid residue is bound to at least one non-reducing end of a glucan, and the glucan is a branched α-1,4 glucan or a linear α-1,4 glucan. The glucuronic acid-containing glucan of the present invention can be provided by allowing α-glucan phosphorylase derived from Aquifex aeolicus VF5 to act on glucuronic acid-1-phosphate to thereby transfer a glucuronic acid residue to the non-reducing end of the receptor glucan.
摘要翻译： 本发明的目的是提供一种含糖醛酸的葡聚糖或其改性产物。 本发明的含葡萄糖醛酸的葡聚糖是葡萄糖醛酸的葡聚糖，其中葡萄糖醛酸残基与葡聚糖的至少一个非还原末端结合，葡聚糖是支链的α-1,4葡聚糖或 线型α-1,4葡聚糖。 本发明的含葡萄糖醛酸的葡聚糖可以通过使来源于水溶性水蛭素VF5的α-葡聚糖磷酸化酶作用于葡糖醛酸-1-磷酸酯上，从而将葡萄糖醛酸残基转移到受体葡聚糖的非还原末端来提供 。
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公开(公告)号：US12091697B2
公开(公告)日：2024-09-17
申请号：US17260168
申请日：2019-07-11
发明人： Chun You , Dongdong Meng
CPC分类号： C12P19/26 , C12Y204/01001 , C12Y204/01007 , C12Y204/0102 , C12Y204/01049 , C12Y305/99006 , C12Y503/01009 , C12Y504/02002
摘要： A method for preparing glucosamine includes the steps of converting fructose-6-phosphate (F6P) and an ammonium salt to glucosamine-6-phosphate (GlcN6P) under the catalysis of glucosamine-6-phosphate deaminase (EC 3.5.99.6, GlmD); and producing glucosamine (GlcN) by the dephosphorylation of GlcN6P under the catalysis of an enzyme capable of catalyzing the dephosphorylation. Such a method can be used to prepare glucosamine by in vitro enzymatic biosystem.
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公开(公告)号：US20240200109A9
公开(公告)日：2024-06-20
申请号：US17627488
申请日：2020-07-17
申请人： BONUMOSE, INC.
IPC分类号： C12P19/02 , C12N9/10 , C12N9/16 , C12N9/90 , C12N11/091
CPC分类号： C12P19/02 , C12N9/1051 , C12N9/107 , C12N9/16 , C12N9/90 , C12N11/091 , C12Y204/01001 , C12Y204/01018 , C12Y301/03 , C12Y501/03 , C12Y503/01009 , C12Y504/02002
摘要： The invention relates to immobilized enzyme compositions for the preparation of a hexose. Hexoses include, for example, tagatose, psicose, fructose, allose, mannose, galactose, altrose, talose, sorbose, gulose, idose, and inositol. The invention also relates to an enzymatic process for preparing a hexose from a saccharide by contacting a starch derivative with an immobilized enzyme composition of the invention.
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