公开(公告)号：US12115335B2

公开(公告)日：2024-10-15

申请号：US17153613

申请日：2021-01-20

申请人： Becton, Dickinson and Company

发明人： Margarita Falkovich

IPC分类号： A61M5/00 ,  A61L2/00 ,  A61L2/10 ,  A61M5/142 ,  A61M5/162 ,  A61M5/145 ,  A61M5/20 ,  A61M5/24

CPC分类号： A61M5/001 ,  A61L2/0047 ,  A61L2/10 ,  A61M5/14248 ,  A61M5/162 ,  A61L2202/14 ,  A61L2202/182 ,  A61L2202/21 ,  A61M2005/14252 ,  A61M5/14566 ,  A61M5/20 ,  A61M2005/247 ,  A61M2205/053 ,  A61M2205/3317 ,  A61M2205/585 ,  A61M2205/8206 ,  A61M2209/10

摘要： A drug delivery system for injecting a medicament includes a housing defining a cavity, a container received within the cavity and configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly received within the cavity and configured to drive the stopper within the container, a needle actuator assembly received within the cavity and comprising a needle configured to be placed in fluid communication with the container, the needle moveable from a first position and a second position spaced from the first position, and a sterilizer received within the cavity and configured to sterilize at least one of the container, the drive assembly, and the needle actuator assembly upon activation of the drug delivery system.

公开(公告)号：US12115295B2

公开(公告)日：2024-10-15

申请号：US17555630

申请日：2021-12-20

申请人： Fresenius Medical Care Holdings, Inc.

发明人： Kelly Yik ,  Daniel Schmidt ,  Aiyuan Wang ,  Deryu Chen ,  Christopher McCormick ,  Evan Zaro

IPC分类号： A61M1/16 ,  A61L2/00 ,  A61L2/26

CPC分类号： A61M1/168 ,  A61L2/0047 ,  A61L2/26 ,  A61L2202/11 ,  A61L2202/122 ,  A61L2202/14 ,  A61L2202/21 ,  A61L2202/22 ,  A61L2202/24 ,  A61M2205/11 ,  A61M2205/3306 ,  A61M2205/3368 ,  A61M2206/12

摘要： A hemodialysis system including one or more ultraviolet chambers is disclosed. The hemodialysis system including a dialyzer arranged and configured to filter a patient's blood, a hemodialysis machine arranged and configured to pump, move, or the like dialysate through the dialyzer, the hemodialysis machine including an outlet valve and an outlet fluid flow path to pump or move dialysate from the hemodialysis machine to the dialyzer, and an inlet valve and an inlet fluid flow path to pump or receive dialysate from the dialyzer, and one or more ultraviolet chambers arranged and configured to kill bacteria, viruses, or a combination thereof. Thus arranged, by incorporating one or more ultraviolet chambers in strategic areas of the system, the ultraviolet chambers may eliminate, or at least greatly reduce, the possibility of cross-contamination in, for example, the dialysate, and thus eliminate the need for disinfecting the system between treatments.

公开(公告)号：US20240261088A1

公开(公告)日：2024-08-08

申请号：US18592481

申请日：2024-02-29

申请人： ALCON INC.

发明人： Marec Weber

IPC分类号： A61F2/16 ,  A61B50/00 ,  A61B50/30 ,  A61B90/00 ,  A61J1/00 ,  A61L2/26 ,  B65B69/00

CPC分类号： A61F2/1691 ,  A61B50/00 ,  A61B50/30 ,  A61J1/00 ,  A61L2/26 ,  B65B69/00 ,  B65B69/0058 ,  A61B2050/0051 ,  A61B2050/0065 ,  A61B2050/3008 ,  A61B2090/0807 ,  A61L2202/12 ,  A61L2202/181 ,  A61L2202/182 ,  A61L2202/21 ,  A61L2202/24

摘要： A system and method for systematic, controlled removal of sterile products from blister packs for use during surgery is disclosed.

公开(公告)号：US20240181104A1

公开(公告)日：2024-06-06

申请号：US18527045

申请日：2023-12-01

申请人： ENTEGRIS, INC.

发明人： Jürgen Michael Lobert ,  Joseph Wildgoose ,  Reena Srivastava ,  Edward John Washington

IPC分类号： A61L2/20 ,  A24B15/18 ,  A61L2/00 ,  B01D53/46 ,  B01D53/81 ,  B01J20/04 ,  B01J20/20 ,  B01J20/28

CPC分类号： A61L2/208 ,  A24B15/183 ,  A61L2/0094 ,  B01D53/46 ,  B01D53/81 ,  B01J20/041 ,  B01J20/046 ,  B01J20/20 ,  B01J20/2804 ,  A61L2202/122 ,  A61L2202/123 ,  A61L2202/13 ,  A61L2202/21 ,  A61L2202/24 ,  A61L2202/25 ,  B01D2253/102 ,  B01D2253/25 ,  B01D2253/34

摘要： Described are processes and equipment that are useful to remove hydrogen peroxide from a gas, for example from a hospital room as a step of sterilizing the room using hydrogen peroxide, or from a flow of exhaust air that is produced by sterilization equipment that uses hydrogen peroxide as a sterilizing agent.

公开(公告)号：US11981588B2

公开(公告)日：2024-05-14

申请号：US17177653

申请日：2021-02-17

申请人： THE CLEVELAND CLINIC FOUNDATION ,  PARKER-HANNIFIN CORPORATION

发明人： Joseph Foss ,  William Kolosi ,  Dale Ashby ,  Gino Banco ,  Paul Resendes

IPC分类号： C02F1/68 ,  A61G12/00 ,  A61L2/00 ,  A61L2/02 ,  A61L2/26 ,  A61L9/00 ,  C02F1/00 ,  C02F1/02 ,  C02F1/28 ,  C02F1/32 ,  C02F1/42 ,  C02F1/44 ,  C02F1/469 ,  C02F1/50 ,  C02F9/00 ,  C02F9/20 ,  C02F101/20 ,  C02F103/02 ,  G01N35/04 ,  G01N35/10

CPC分类号： C02F1/687 ,  A61G12/001 ,  A61G12/008 ,  A61L2/0017 ,  A61L2/022 ,  A61L2/26 ,  A61L9/00 ,  C02F1/008 ,  C02F1/50 ,  C02F9/20 ,  A61L2202/21 ,  C02F1/001 ,  C02F1/02 ,  C02F1/283 ,  C02F1/32 ,  C02F1/42 ,  C02F2001/427 ,  C02F1/444 ,  C02F1/4691 ,  C02F1/68 ,  C02F2101/20 ,  C02F2103/026 ,  C02F2201/006 ,  C02F2201/008 ,  C02F2209/006 ,  C02F2209/02 ,  C02F2209/03 ,  C02F2209/05 ,  C02F2209/06 ,  C02F2209/40 ,  C02F2301/043 ,  C02F2303/04 ,  G01N2035/0443 ,  G01N35/1002

摘要： One aspect of the present disclosure can include a system for dispensing purified and sterilized fluid and/or solution. The delivery system can include a fluid reservoir, a sterilization and/or purification mechanism, a solution production mechanism, a dispensing mechanism, and a controller. The system can dispense the purified and sterilized fluid and/or solution on-demand.

公开(公告)号：US11925718B2

公开(公告)日：2024-03-12

申请号：US16091649

申请日：2016-12-08

申请人： Metall + Plastic GmbH

发明人： Stefan Kleinmann

IPC分类号： A61L2/20 ,  A61L2/22 ,  A61L2/26 ,  G21F7/04

CPC分类号： A61L2/208 ,  A61L2/22 ,  A61L2/26 ,  G21F7/04 ,  A61L2202/11 ,  A61L2202/12 ,  A61L2202/122 ,  A61L2202/15 ,  A61L2202/21

摘要： A decontamination assembly (1) for pharmaceutical applications, comprising an isolator (2) having a manipulator chamber (3) and a plenum chamber (4) which is disposed above the manipulator chamber (3) and which can be supplied with an air flow (9) via at least one circulation fan (7) disposed in a circulating-air generation chamber, a membrane (5) for generating a laminar air flow (11) in the manipulator chamber (3) during a working operating state being disposed between the plenum chamber (4) and the manipulator chamber (3), the manipulator chamber (3) being connected to the circulating-air generation chamber (6) in an air-conducting manner via a return-air channel (12), further comprising ultrafine distributing means (19), for producing a decontaminant/air mixture based on a liquid decontaminant stock, a stock of H2O2, the ultrafine distributing means (19) being connected to the plenum chamber (4) via at least one plenum supply line (25) leading into the plenum chamber (4) so as to directly supply the plenum chamber (4) with the decontaminant/air mixture when in a decontamination operating state, wherein the ultrafine distributing means (19) are connected directly to the manipulator chamber (3) via at least one manipulator supply line (27) so as to directly supply the manipulator chamber (3) with the decontaminant/air mixture when in the decontamination operating state.

公开(公告)号：US11858675B2

公开(公告)日：2024-01-02

申请号：US17465486

申请日：2021-09-02

申请人： CROSSROADS EXTREMITY SYSTEMS, LLC

发明人： Robert Glen Coleman ,  Michael Chad Hollis ,  Vernon Raymond Hartdegen

IPC分类号： A61M5/32 ,  B65B55/04 ,  A61B17/80 ,  A61L2/04 ,  A61F2/00 ,  B65B55/12 ,  A61B50/36 ,  G06Q90/00 ,  A61B50/30 ,  A61B50/33 ,  A61B90/70

CPC分类号： B65B55/04 ,  A61B17/80 ,  A61B50/30 ,  A61B50/33 ,  A61B50/36 ,  A61F2/0095 ,  A61L2/04 ,  B65B55/12 ,  G06Q90/00 ,  A61B90/70 ,  A61B2050/3008 ,  A61L2202/21 ,  A61L2202/24

摘要： A terminally sterilized medical procedure kit includes a recovered item and a new item packaged together as a single stock keeping unit. A method for processing at least a portion of a first medical procedure kit includes the steps of receiving a recoverable item of the first kit, performing a processing operation on the recoverable item, providing a new item, combining the recoverable item and the new item in a second kit, and terminally sterilizing the second kit. A method for recovering at least a portion of a terminally sterilized medical procedure kit includes the steps of purchasing a recoverable item of the first kit from an owner and receiving the recoverable item by the purchaser.

公开(公告)号：US11844890B2

公开(公告)日：2023-12-19

申请号：US18157741

申请日：2023-01-20

申请人： Sequana Medical NV

发明人： Jeffrey Testani ,  Christopher McIntyre ,  Ian Crosbie ,  Oliver Goedje

IPC分类号： A61M1/28 ,  A61K9/00 ,  A61K9/08 ,  A61K31/7004 ,  A61K31/716 ,  A61M27/00 ,  A61M31/00 ,  A61K33/14 ,  A61F7/08 ,  A61P7/08 ,  A61L2/00

CPC分类号： A61M1/282 ,  A61F7/08 ,  A61K9/0019 ,  A61K9/08 ,  A61K31/7004 ,  A61K31/716 ,  A61K33/14 ,  A61M1/28 ,  A61M1/285 ,  A61M1/287 ,  A61M27/002 ,  A61M31/002 ,  A61L2/0047 ,  A61L2202/21 ,  A61M2205/18 ,  A61M2205/3317 ,  A61M2205/3337 ,  A61M2205/3344 ,  A61M2205/3368 ,  A61M2205/3379 ,  A61M2205/3569 ,  A61M2205/3576 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/587 ,  A61M2205/6009 ,  A61M2205/70 ,  A61M2205/8206 ,  A61M2205/8243 ,  A61M2209/086 ,  A61M2209/088 ,  A61M2210/1017 ,  A61M2210/1085

摘要： A direct sodium removal (“DSR”) infusate regimen and methods of use are provided for removing sodium and reducing fluid overload in patients with severe renal dysfunction and/or heart failure, in which a patient has at least a first DSR session with a first DSR infusate having no or low sodium that is instilled into a patient's peritoneal cavity for a first dwell period to cause sodium and excess fluid to migrate to the patient's peritoneal cavity, and thereafter, the patient may undergo conventional dialysis to rebalance the patient's fluid and sodium levels.

公开(公告)号：US20230346995A1

公开(公告)日：2023-11-02

申请号：US17923056

申请日：2021-05-11

申请人： THE TRUSTEES OF INDIANA UNIVERSITY

发明人： Chandan K. SEN ,  Sashwati ROY

IPC分类号： A61L2/03 ,  A61K33/38 ,  A61K33/28 ,  A61K31/496 ,  A61P31/10 ,  A61P31/04 ,  A61N1/40

CPC分类号： A61L2/03 ,  A61K33/38 ,  A61K33/28 ,  A61K31/496 ,  A61P31/10 ,  A61P31/04 ,  A61N1/40 ,  A61L2202/21

摘要： Compositions and methods are provided for treating an article that is susceptible to contamination by an antimicrobial-resistant microorganism, wherein the susceptible article is exposed to an optimized electric current or field. Methods to treat an individual in need of therapy are also provided, including for example, individuals having a bacterial, viral, fungal, or parasitic infection, or individuals having an antimicrobial-resistant microbial infection, e.g., in a wound, by applying a predetermined electric current to the individual. The methods disclosed herein can be used in conjunction with a therapeutic pharmaceutical composition comprising an antimicrobial agent such as an antifungal or antibiotic pharmaceutical.

公开(公告)号：US11779684B2

公开(公告)日：2023-10-10

申请号：US17459517

申请日：2021-08-27

申请人： NANOVIS, LLC

发明人： Matthew Hedrick ,  Chang Yao

IPC分类号： A61L27/54 ,  C23C22/05 ,  C25D11/02 ,  C23C22/78 ,  A61L27/04 ,  A61L27/30 ,  C25D11/26 ,  C25D11/34 ,  C09D1/00 ,  C09D7/61 ,  C04B35/447 ,  C04B35/622 ,  C09D5/14

CPC分类号： A61L27/54 ,  A61L27/04 ,  A61L27/306 ,  C04B35/447 ,  C04B35/62222 ,  C09D1/00 ,  C09D5/14 ,  C09D7/61 ,  C23C22/05 ,  C23C22/78 ,  C25D11/02 ,  C25D11/26 ,  C25D11/34 ,  A61L2202/21 ,  A61L2300/102 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/61 ,  A61L2400/12 ,  A61L2420/02 ,  C04B2235/447

摘要： An antimicrobial medical device that includes a substrate having a metal surface that is made from a metal or metal alloy that may include stainless steel, cobalt, and titanium. Disposed on the metal surface is a first antimicrobial oxide layer that includes an antimicrobial metal that may include silver, copper, and zinc, and combinations thereof. The atoms of antimicrobial metal in the first antimicrobial oxide layer are of a first concentration. The first antimicrobial oxide layer is positioned in a direction opposite that of the metal surface. The device further includes a second antimicrobial oxide layer that includes an antimicrobial metal that may be silver, copper, and zinc, and combinations thereof. The atoms of the antimicrobial metal present in the second antimicrobial oxide layer are of a second concentration. The first concentration and the second concentration are not equal. Methods for making the antimicrobial medical device are also disclosed.