公开(公告)号：US11666224B2

公开(公告)日：2023-06-06

申请号：US15774070

申请日：2016-11-07

申请人： Purdue Research Foundation

发明人： Ji-xin Cheng ,  Pu Wang ,  Lu Lan ,  Yan Xia ,  Ke Huo

IPC分类号： A61B5/00 ,  A61B90/00 ,  A61B5/06 ,  A61B34/20 ,  A61B17/32 ,  A61B17/3205 ,  A61B17/50 ,  A61B8/08 ,  A61B90/30 ,  A61B90/50 ,  A61B17/00 ,  G01N33/48

CPC分类号： A61B5/0095 ,  A61B5/061 ,  A61B5/4836 ,  A61B5/6851 ,  A61B5/743 ,  A61B17/3205 ,  A61B17/320016 ,  A61B34/20 ,  A61B90/36 ,  A61B90/37 ,  G01N33/48 ,  A61B5/064 ,  A61B5/7445 ,  A61B8/0825 ,  A61B17/50 ,  A61B2017/008 ,  A61B2017/00707 ,  A61B2034/2057 ,  A61B2090/306 ,  A61B2090/365 ,  A61B2090/378 ,  A61B2090/502

摘要： A lesion detection system for use with a patient, comprising an optoacoustic guide wire assembly configured to be insertable into a patient's tissue. The optical acoustic guide wire assembly can be comprised of an optical waveguide have a first end and a second end, a light source coupled to the second end of the optical waveguide, wherein said light source configured to emit energy to the patient's tissue, at least one transducer configured to detect an ultrasound signal emitted from the patient's tissue in response to energy emitted from the light source, and a computer system.

公开(公告)号：US20170319102A1

公开(公告)日：2017-11-09

申请号：US15481431

申请日：2017-04-06

申请人： CIANNA MEDICAL, INC.

发明人： John E. Greene ,  Nikolai Rulkov ,  Jonathan White

IPC分类号： A61B5/06 ,  A61B90/00 ,  H01L23/60 ,  A61B90/98

CPC分类号： A61B5/064 ,  A61B5/062 ,  A61B34/20 ,  A61B90/04 ,  A61B90/39 ,  A61B90/98 ,  A61B2017/00212 ,  A61B2017/00411 ,  A61B2017/008 ,  A61B2017/00867 ,  A61B2017/0088 ,  A61B2034/2051 ,  A61B2034/306 ,  A61B2090/306 ,  A61B2090/3908 ,  A61B2090/397 ,  A61B2090/3975 ,  A61B2090/3979 ,  A61B2090/3987 ,  H01L23/60 ,  H01L24/48 ,  H01L25/167 ,  H01L2224/48091 ,  H01L2224/48227 ,  H01L2224/48465 ,  H01L2924/00014 ,  H01L2224/45099 ,  H01L2924/00012 ,  H01L2924/00

摘要： Markers and related systems and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The marker includes one or more photosensitive diodes for transforming light pulses striking the marker into electrical energy, one or more antennas, and a switch coupled to the photodiodes and antennas such that the light pulses cause the switch to open and close and modulate radar signals reflected by the marker back to a source of the signals. The antenna(s) may include one or more wire elements extending from a housing, one or more antenna elements printed on a substrate, or one or more chip antennas. Optionally, the marker may include a processor coupled to the photodiodes for identifying signals in the light pulses or one or more coatings or filters to allow selective activation of the marker.

公开(公告)号：US20170181842A1

公开(公告)日：2017-06-29

申请号：US15455977

申请日：2017-03-10

申请人： Focal Therapeutics, Inc.

发明人： Gail S. LEBOVIC ,  David B. WILLIS ,  George D. HERMANN ,  Jonathan M. OLSON

IPC分类号： A61F2/12 ,  A61B17/00

CPC分类号： A61F2/12 ,  A61B17/00 ,  A61B17/0206 ,  A61B2017/008 ,  A61B2090/3908 ,  A61F2210/0004 ,  A61F2230/0008 ,  A61F2230/0013 ,  A61F2230/0076 ,  A61F2230/0091 ,  A61F2250/0059 ,  A61F2250/0097 ,  A61F2250/0098

摘要： Described herein are devices for placement in surgically created soft tissue spaces, potential spaces, or cavities. The implantable devices generally include a bioabsorbable body having an open framework that facilitates attachment of tissue thereto in a manner that helps avoid post-surgical deformities. Methods for using the implantable devices in oncoplastic surgery are further described.

公开(公告)号：US20160242855A1

公开(公告)日：2016-08-25

申请号：US15004289

申请日：2016-01-22

申请人： Queen's University at Kingston

发明人： Gabor Fichtinger ,  Tamas Ungi ,  John F. Rudan ,  Andras Lasso ,  C. Jay Engel ,  Gabrielle Gauvin ,  Caitlin Yeo

IPC分类号： A61B34/20 ,  A61B5/06 ,  A61B17/32 ,  A61B34/00 ,  A61N5/10

CPC分类号： A61B34/20 ,  A61B5/062 ,  A61B17/320016 ,  A61B17/3403 ,  A61B34/76 ,  A61B2017/00115 ,  A61B2017/00292 ,  A61B2017/008 ,  A61B2017/3405 ,  A61B2017/3413 ,  A61B2034/2051 ,  A61N5/1001 ,  A61N5/1015 ,  A61N5/1049

摘要： An apparatus and method for surgical tracking comprises an imaging device that generates an image of a tissue volume; an electromagnetic (EM) sensor that creates a reference frame for EM tracking in three dimensions; at least one EM sensor adapted to be attached to the tissue to track local deformation and movement of the tissue volume; a processor that registers the image with the EM-tracked tissue volume and surgical tool in real time, and produces an output; and a feedback device that provides feedback about the location of the surgical tool relative to the tissue volume, based on the processor output. Embodiments are particularly useful in soft tissue, such as breast, where deformation before and during a procedure such as tumor resection complicate tracking of the tissue volume and a surgical tool.

摘要翻译： 用于手术跟踪的装置和方法包括：生成组织体积的图像的成像装置; 电磁（EM）传感器，其在三维中创建用于EM跟踪的参考系; 至少一个EM传感器，适于附接到所述组织以跟踪所述组织体积的局部变形和移动; 实时记录EM跟踪的组织体积和手术工具的处理器，并产生输出; 以及反馈装置，其基于处理器输出提供关于外科手术工具相对于组织体积的位置的反馈。 实施例在诸如乳房的软组织中特别有用，其中在诸如肿瘤切除术之前和期间的变形使组织体积的跟踪复杂化，并且手术工具。

公开(公告)号：US20160199133A1

公开(公告)日：2016-07-14

申请号：US15078648

申请日：2016-03-23

申请人： Boston Scientific Scimed, Inc.

发明人： John Lingeman ,  Jennifer Keeler

IPC分类号： A61B18/26 ,  A61B17/221 ,  A61B17/22

CPC分类号： A61B17/22012 ,  A61B17/221 ,  A61B18/22 ,  A61B18/26 ,  A61B2017/00353 ,  A61B2017/00371 ,  A61B2017/0038 ,  A61B2017/00469 ,  A61B2017/008 ,  A61B2017/22038 ,  A61B2017/2924 ,  A61B2017/2946 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2217/005

摘要： A device may include a sheath including a lumen, a distal end, and a proximal end. The device may further include an end-effector unit and an elongate member connected to the end-effector unit. The end-effector unit and the sheath may be movable relative to each other to achieve a first state of the end-effector unit and a second state of the end-effector unit. Moreover, the medical device may include a handle having a first handle portion connected to the proximal end of the sheath, a second handle portion connected to the proximal end of the elongate member, and a compliant member longitudinally aligned with the sheath between the first handle portion and the second handle portion. The first and second handle portions may be configured such that relative movement of the first and second handle portions causes the end-effector to move between the first and second states.

公开(公告)号：US20160192960A1

公开(公告)日：2016-07-07

申请号：US15068119

申请日：2016-03-11

申请人： Raphael Bueno ,  Jayender Jagadeesan ,  Ferenc A. Jolesz

发明人： Raphael Bueno ,  Jayender Jagadeesan ,  Ferenc A. Jolesz

IPC分类号： A61B17/32 ,  A61B90/00 ,  A61B34/20 ,  A61B17/068 ,  A61B18/14

CPC分类号： A61B34/20 ,  A61B5/066 ,  A61B5/7455 ,  A61B17/068 ,  A61B17/07207 ,  A61B17/320016 ,  A61B17/3205 ,  A61B17/50 ,  A61B18/1477 ,  A61B90/361 ,  A61B90/37 ,  A61B90/39 ,  A61B2017/00115 ,  A61B2017/00119 ,  A61B2017/00292 ,  A61B2017/00296 ,  A61B2017/00349 ,  A61B2017/008 ,  A61B2017/00809 ,  A61B2017/00867 ,  A61B2017/07271 ,  A61B2017/2927 ,  A61B2018/00642 ,  A61B2018/00827 ,  A61B2018/00904 ,  A61B2034/2051 ,  A61B2090/061 ,  A61B2090/067 ,  A61B2090/0807 ,  A61B2090/376 ,  A61B2090/3904 ,  A61B2090/3908 ,  A61B2090/3958 ,  A61B2090/3975 ,  A61B2090/3987 ,  A61B2090/3991 ,  A61B2562/0204 ,  A61B2562/0233 ,  A61B2576/00

摘要： Embodiments of the invention provide a system and method for resecting a tissue mass. The system for resecting a tissue mass includes a surgical instrument and a first sensor for measuring a signal corresponding to the position and orientation of the tissue mass. The first sensor is dimensioned to fit insider or next to the tissue mass. The system also includes a second sensor attached to the surgical instrument configured to measure the position and orientation of the surgical instrument. The second sensor is configured to receive the signal from the first sensor. A controller is in communication with the first sensor and/or the second sensor, and the controller executes a stored program to calculate a distance between the first sensor and the second sensor. Accordingly, visual, auditory, haptic or other feedback is provided to the clinician to guide the surgical instrument to the surgical margin.

摘要翻译： 本发明的实施例提供一种用于切除组织块的系统和方法。 用于切除组织块的系统包括外科器械和用于测量与组织块的位置和取向相对应的信号的第一传感器。 第一个传感器的尺寸适合内部人员或组织块的旁边。 该系统还包括附接到外科器械的第二传感器，其被配置成测量外科器械的位置和取向。 第二传感器被配置为从第一传感器接收信号。 控制器与第一传感器和/或第二传感器通信，并且控制器执行存储的程序以计算第一传感器和第二传感器之间的距离。 因此，向临床医生提供视觉，听觉，触觉或其他反馈以将手术器械引导至外科边缘。

公开(公告)号：US09291792B2

公开(公告)日：2016-03-22

申请号：US14298010

申请日：2014-06-06

申请人： Boston Scientific Scimed, Inc.

发明人： William Asselin ,  Jessica Hixon ,  Michael O'Brien ,  Michael Melanson ,  Ty Fairneny

IPC分类号： G02B6/26 ,  G02B7/00 ,  A61B18/22 ,  A61B17/42 ,  A61B18/24 ,  A61B17/00 ,  A61B18/00

CPC分类号： G02B7/00 ,  A61B17/42 ,  A61B18/22 ,  A61B18/24 ,  A61B2017/00274 ,  A61B2017/008 ,  A61B2017/00805 ,  A61B2018/00547 ,  A61B2018/2255 ,  Y10T29/49826

摘要： Embodiments of the invention include an apparatus including an optical fiber having a distal end configured to emit a beam of energy. The apparatus also includes a tube including a tube channel. The distal end of the optical fiber is disposed in the tube channel. The apparatus further includes a shock absorber disposed on the tube and a cap disposed on the shock absorber.

摘要翻译： 本发明的实施例包括一种包括光纤的设备，该光纤具有被配置为发射能量束的远端。 该装置还包括一个包括管道的管子。 光纤的远端设置在管道中。 该装置还包括设置在管上的减震器和设置在减震器上的盖。

公开(公告)号：US08634899B2

公开(公告)日：2014-01-21

申请号：US11275919

申请日：2006-02-03

申请人： Ryan L. Goosen ,  Steven E. Field ,  Richard M. Chesbrough

发明人： Ryan L. Goosen ,  Steven E. Field ,  Richard M. Chesbrough

IPC分类号： A61B5/05

CPC分类号： A61B90/39 ,  A61B2017/008 ,  A61B2017/00831 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3987

摘要： The invention provides a device for percutaneously implanting an imaging marker for identifying a location within a tissue mass. The subcutaneous imaging marker comprises at least a first element and a second element, each of which have a primary imaging mode. The primary imaging mode of the first element is different from that of the second element.

摘要翻译： 本发明提供一种用于经皮植入用于识别组织块内的位置的成像标记物的装置。 皮下成像标记物至少包括第一元件和第二元件，每个元件具有主要成像模式。 第一元件的主要成像模式与第二元件的主要成像模式不同。

公开(公告)号：US20130237981A1

公开(公告)日：2013-09-12

申请号：US13872521

申请日：2013-04-29

申请人： BOSTON SCIENTIFIC SCIMED, INC.

发明人： Janel L. Lanphere ,  Paul DiCarlo ,  Steven M. Anderson

IPC分类号： A61B18/18

CPC分类号： A61B18/18 ,  A61B18/14 ,  A61B18/1815 ,  A61B90/04 ,  A61B2017/008 ,  A61B2090/0472 ,  A61B2090/0481 ,  A61B2090/049 ,  A61K9/0019 ,  A61K47/30 ,  A61L27/3683 ,  A61N7/02

摘要： Polymer insulators and methods of using polymer insulators are disclosed. In some embodiments, a method includes separating a first portion of a subject's tissue from a second portion of the subject's tissue so that there is a space between the first and second portions of tissue. Deionized water, a buffered saline solution, liquid polymers, gels, particles, foams, and/or gases are disposed between the first and second portions of tissue, and the first portion of tissue is exposed to energy to treat the first portion of tissue.

摘要翻译： 公开了聚合物绝缘体和使用聚合物绝缘体的方法。 在一些实施例中，一种方法包括将受试者组织的第一部分与受试者组织的第二部分分开，使得在组织的第一和第二部分之间存在空间。 去离子水，缓冲盐溶液，液体聚合物，凝胶，颗粒，泡沫和/或气体设置在组织的第一和第二部分之间，并且组织的第一部分暴露于能量以处理组织的第一部分。

公开(公告)号：US20120259242A1

公开(公告)日：2012-10-11

申请号：US13525912

申请日：2012-06-18

申请人： James W. VETTER ,  Scott C. ANDERSON ,  Jordan S. TUTTLE ,  Daniel M. BROUNSTEIN

发明人： James W. VETTER ,  Scott C. ANDERSON ,  Jordan S. TUTTLE ,  Daniel M. BROUNSTEIN

IPC分类号： A61B10/02

CPC分类号： A61B10/0041 ,  A61B10/02 ,  A61B10/0266 ,  A61B10/0283 ,  A61B10/04 ,  A61B17/320016 ,  A61B17/32056 ,  A61B17/320725 ,  A61B17/3439 ,  A61B17/3476 ,  A61B18/14 ,  A61B18/148 ,  A61B18/1482 ,  A61B90/39 ,  A61B2017/00734 ,  A61B2017/008 ,  A61B2017/22034 ,  A61B2017/22047 ,  A61B2017/306 ,  A61B2017/3488 ,  A61B2018/00011 ,  A61B2018/1407 ,  A61B2018/1475 ,  A61B2090/3782 ,  A61B2090/3908 ,  A61B2217/005 ,  A61B2218/002 ,  A61B2218/007 ,  A61B2218/008 ,  A61M1/0023

摘要： A needle is used to mark a tissue area of interest. The needle may have one or more indicators which indicate selected angular orientations relative to the needle. The indicators may also be coupled to anchors which are deployed in the tissue to anchor the needle in the tissue. The needle may be positioned to guide an excisional device to remove tissue.

摘要翻译： 针用于标记感兴趣的组织区域。 针可以具有一个或多个指示器，其指示相对于针的所选角度取向。 指示器还可以联接到部署在组织中的锚固件以将针固定在组织中。 针可以定位成引导切除装置以去除组织。