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公开(公告)号:US4434179A
公开(公告)日:1984-02-28
申请号:US353887
申请日:1982-03-02
申请人: Shinsaku Kobayashi , Akira Ogiso
发明人: Shinsaku Kobayashi , Akira Ogiso
IPC分类号: A61K31/045 , A61K31/08 , A61K31/09 , A61K31/215 , A61K31/22 , A61K31/235 , A61P17/00 , A61P43/00 , C07C33/02 , C07C69/007 , A61K31/075
CPC分类号: A61K31/235 , A61K31/045 , A61K31/08 , A61K31/09 , A61K31/22 , Y10S514/927 , Y10S514/928
摘要: Compounds of formula (I): ##STR1## (wherein: R.sup.1 represents a hydroxy group, a C.sub.1 -C.sub.8 alkoxy group, an aliphatic acyloxy group, a benzoyloxy group or a cinnamoyloxy group; p1 R.sup.2 represents a hydrogen atom, a C.sub.1 -C.sub.8 alkyl group, an aliphatic acyl group, a benzoyl group or a cinnamoyl group; andn represents an integer from 1 to 3)when applied topically have been found to promote wound-healing and exuberant granulation; they are preferably formulated with a pharmaceutical topical base.
摘要翻译: 式(I)化合物:其中:R1表示羟基,C1-C8烷氧基,脂族酰氧基,苯甲酰氧基或肉桂酰氧基; p1R2表示氢原子, C1-C8烷基,脂肪族酰基,苯甲酰基或肉桂酰基; n表示1〜3的整数),可以促进伤口愈合和旺盛的造粒; 它们优选用药物局部基质配制。
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公开(公告)号:US4199519A
公开(公告)日:1980-04-22
申请号:US938356
申请日:1978-08-31
申请人: Hiroshi Mishima , Akira Ogiso , Shinsaku Kobayashi
发明人: Hiroshi Mishima , Akira Ogiso , Shinsaku Kobayashi
IPC分类号: C07C59/42 , C07D295/13 , C07D295/185 , C07D317/58 , C07C57/02 , C07C69/52
CPC分类号: C07D295/185 , C07C45/68 , C07C59/42 , C07D295/13 , C07D317/58 , Y10S514/927
摘要: Polyprenyl derivatives having the formula ##STR1## [wherein A and B individually represent a group of the formula --CH.sub.2 OR.sup.1 (wherein R.sup.1 is hydrogen atom, an alkyl group having an intervening hetero atom in the carbon chain, carboxyl group on its salt or an aliphatic acyl group optionally having an intervening hetero atom in the carbon chain, an aromatic acyl group, a heterocyclic acyl group, an araliphatic acyl group, a heterocyclic aliphatic acyl group or a radical of an inorganic acid or its salt) or where one of A and B represents the group --CH.sub.2 OR.sup.1, the other represents a group of the formula --COOR.sup.2 (wherein R.sup.2 represents hydrogen atom, a metal atom capable of forming a salt, an organic base or an akyl group), a group of the formula ##STR2## or a group of the formula ##STR3## (wherein R.sup.3 and R.sup.4 may be the same or different and each represents hydrogen atom, an alkyl group optionally having a heterocyclic substituent, an aryl group or an aralkyl group or R.sup.3 and R.sup.4 may jointly form a ring optionally containing other hetero ring atom) and n is an integer of 0 to 4 inclusive, provided that when both A and B are the group --CH.sub.2 OR.sup.1, either of the R.sup.1 represents an alkyl group having an intervening hetero atom, carboxyl group or its salt, an aliphatic acyl group having an intervening hetero atom in the carbon chain, a heterocyclic acyl group, a heterocyclic aliphatic acyl group or a radical of an inorganic acid or its salt]. These derivatives are useful as medicines for treating peptic ulcer.
摘要翻译: 具有式
的聚丙烯衍生物[其中A和B各自表示式-CH 2 OR 1的基团(其中R 1是氢原子,在碳链中具有中间杂原子的烷基,其盐上的羧基或脂族 任选在碳链中具有中间杂原子的酰基,芳族酰基,杂环酰基,芳脂酰基,杂环脂族酰基或无机酸或其盐的基团),或者其中A和 B表示基团-CH 2 OR 1,另一个表示式-COOR 2(其中R 2表示氢原子,能够形成盐的金属原子,有机碱或烷基)的基团,式 或式(IMA)(其中R 3和R 4可以相同或不同,各自表示氢原子,任选具有杂环取代基的烷基,芳基或芳烷基或R 3和R 4可以共同形成 戒指 任选地含有其它杂环原子),n为0〜4的整数,条件是当A和B都为基团-CH 2 OR 1时,R 1表示具有杂原子的烷基,羧基或其盐 ,在碳链中具有插入杂原子的脂族酰基,杂环酰基,杂环脂族酰基或无机酸或其盐的基团]。 这些衍生物可用作治疗消化性溃疡的药物。 -
公开(公告)号:US4260551A
公开(公告)日:1981-04-07
申请号:US11514
申请日:1979-02-12
申请人: Hiroshi Mishima , Akira Ogiso , Shinsaku Kobayashi
发明人: Hiroshi Mishima , Akira Ogiso , Shinsaku Kobayashi
IPC分类号: C07C43/00 , C07C69/007 , C07C69/767 , C09F5/08 , C07C69/76
CPC分类号: C07C69/618 , C07C45/68 , C07C69/007 , C07C69/16 , C07C69/18 , C07C69/28 , C07C69/56 , C07C69/76 , C07C69/78
摘要: Polyprenyl derivatives having the formula ##STR1## in which R.sup.1 and R.sup.2 may be the same or different and each represents hydrogen atom, hydroxyl group, an alkoxy group having 1-8 carbon atoms, an aliphatic acyloxy group having 2-18 carbon atoms, an aromatic acyloxy group or an araliphatic acyloxy group having 2-3 carbon atoms in the aliphatic acyl moiety, R.sup.3 represents hydrogen atom, an alkyl group having 1-8 carbon atoms, an aliphatic acyl group having 2-18 carbon atoms, an aromatic acyl group or an araliphatic acyl group having 2-3 carbon atoms in the aliphatic acyl moiety, n is an integer of 1-4 and, when n is an integer of 2-4, R.sup.2 's may be the same or different; provided that, when n is 1 or 2, at least one of R.sup.1 and R.sup.2 's is hydroxyl group, an alkoxy group, an aliphatic acyloxy group, an aromatic acyloxy group or an araliphatic acyloxy group. These derivatives are useful as medicines for treating peptic ulcer.
摘要翻译: 其中R 1和R 2可以相同或不同并且各自表示氢原子,羟基,具有1-8个碳原子的烷氧基,具有2-羟基的脂肪族酰氧基, 18个碳原子,芳香族酰氧基或脂肪族酰基部分中具有2-3个碳原子的芳脂肪酰氧基,R3表示氢原子,具有1-8个碳原子的烷基,具有2-18个碳原子的脂族酰基 芳香族酰基或脂肪族酰基部分具有2-3个碳原子的芳脂酰基,n为1-4的整数,当n为2-4的整数时,R 2可以相同或不同, 条件是当n为1或2时,R 1和R 2中的至少一个为羟基,烷氧基,脂族酰氧基,芳香族酰氧基或芳脂族酰氧基。 这些衍生物可用作治疗消化性溃疡的药物。
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公开(公告)号:US4192953A
公开(公告)日:1980-03-11
申请号:US1162
申请日:1979-01-04
申请人: Hiroshi Mishima , Akira Ogiso , Shinsaku Kobayashi
发明人: Hiroshi Mishima , Akira Ogiso , Shinsaku Kobayashi
IPC分类号: C07C43/00 , C07C69/007 , A61K31/07 , A61K31/08 , C07C43/02
CPC分类号: C07C41/16 , C07C33/02 , C07C43/15 , C07C45/68 , C07C69/007 , C07C69/16 , C07C69/28 , C07C69/56 , C07C69/618 , C07C69/78 , Y10S514/926 , Y10S514/927
摘要: Polyprenyl derivatives having the formula ##STR1## in which R.sup.1 and R.sup.2 may be the same or different and each represents hydrogen atom, hydroxyl group, an alkoxy group having 1-8 carbon atoms, an aliphatic acyloxy group having 2-18 carbon atoms, an aromatic acyloxy group or an araliphatic acyloxy group having 2-3 carbon atoms in the aliphatic acyl moiety, R.sup.3 represents hydrogen atom, an alkyl group having 1-8 carbon atoms, an aliphatic acyl group having 2-18 carbon atoms, an aromatic acyl group or an araliphatic acyl group having 2-3 carbon atoms in the aliphatic acyl moiety, n is an integer of 1-4 and, when n is an interger of 2-4, R.sup.2 's may be the same or different; provided that, when n is 1 or 2, at least one of R.sup.2 and R.sup.2 's is hydroxyl group, an alkoxy group, an aliphatic acyloxy group, an aromatic acyloxy group or an araliphatic acyloxy group. These derivatives are useful as medicines for treating peptic ulcer.
摘要翻译: 其中R 1和R 2可以相同或不同并且各自表示氢原子,羟基,具有1-8个碳原子的烷氧基,具有2-羟基的脂肪族酰氧基, 18个碳原子,芳香族酰氧基或脂肪族酰基部分中具有2-3个碳原子的芳脂肪酰氧基,R3表示氢原子,具有1-8个碳原子的烷基,具有2-18个碳原子的脂族酰基 芳香酰基或脂肪族酰基部分具有2-3个碳原子的芳脂酰基,n为1-4的整数,当n为2-4的整数时,R 2可以相同或不同; 条件是当n为1或2时,R 2和R 2中的至少一个为羟基,烷氧基,脂族酰氧基,芳香族酰氧基或芳脂族酰氧基。 这些衍生物可用作治疗消化性溃疡的药物。
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公开(公告)号:US4059641A
公开(公告)日:1977-11-22
申请号:US633097
申请日:1975-11-18
申请人: Hiroshi Mishima , Akira Ogiso , Shinsaku Kobayashi
发明人: Hiroshi Mishima , Akira Ogiso , Shinsaku Kobayashi
IPC分类号: C07C69/025 , A61K31/045 , A61K31/075 , A61K31/215 , A61P1/04 , C07C27/00 , C07C33/02 , C07C41/00 , C07C43/00 , C07C43/14 , C07C43/178 , C07C67/00 , C07C69/007
CPC分类号: C07C45/64 , C07C33/02 , C07C41/16 , C07C43/15 , C07C45/68 , C07C69/007 , C07C69/16 , C07C69/18 , C07C69/28 , C07C69/56 , C07C69/614 , C07C69/618 , C07C69/76 , C07C69/78 , C07C69/92 , Y10S514/927
摘要: Polyprenyl derivatives having the formula ##STR1## in which R.sup.1 and R.sup.2 may be the same or different and each represents hydrogen atom, hydroxyl group, an alkoxy group having 1-8 carbon atoms, an aliphatic acyloxy group having 2-18 carbon atoms, an aromatic acyloxy group or an araliphatic acyloxy group having 2-3 carbon atoms in the aliphatic acyl moiety, R.sup.3 represents hydrogen atom, an alkyl group having 1-8 carbon atoms, an aliphatic acyl group having 2-18 carbon atoms, an aromatic acyl group or an araliphatic acyl group having 2-3 carbon atoms in the aliphatic acyl moiety, n is an integer of 1-4 and, when n is an integer of 2-4, R.sup.2 's may be the same or different; provided that, when n is 1 or 2, at least one of R.sup.1 and R.sup.2 's is hydroxyl group, an alkoxy group, an aliphatic acyloxy group, an aromatic acyloxy group or an araliphatic acyloxy group. These derivatives are useful as medicines for treating peptic ulcer.
摘要翻译: 其中R 1和R 2可以相同或不同并且各自代表氢原子,羟基,具有1-8个碳原子的烷氧基,具有2-取代基的脂肪族酰氧基的具有式
+ tr 的聚丙烯基衍生物, 18个碳原子,芳香族酰氧基或脂肪族酰基部分中具有2-3个碳原子的芳脂肪酰氧基,R3表示氢原子,具有1-8个碳原子的烷基,具有2-18个碳原子的脂族酰基 芳香族酰基或脂肪族酰基部分具有2-3个碳原子的芳脂酰基,n为1-4的整数,当n为2-4的整数时,R 2可以相同或不同, 条件是当n为1或2时,R 1和R 2中的至少一个为羟基,烷氧基,脂族酰氧基,芳香族酰氧基或芳脂族酰氧基。 这些衍生物可用作治疗消化性溃疡的药物。 -
公开(公告)号:US4151357A
公开(公告)日:1979-04-24
申请号:US788699
申请日:1977-04-18
申请人: Hiroshi Mishima , Akira Ogiso , Shinsaku Kobayashi
发明人: Hiroshi Mishima , Akira Ogiso , Shinsaku Kobayashi
IPC分类号: C07D307/77 , A61K31/045 , A61K31/08 , A61K31/13 , A61K31/16 , A61K31/19 , A61K31/20 , A61K31/215 , A61K31/23 , A61K31/255 , A61K31/34 , A61K31/343 , A61K31/38 , A61K31/381 , A61K31/382 , A61K31/40 , A61K31/41 , A61K31/435 , A61K31/495 , A61K31/535 , A61K31/54 , A61P1/04 , C07C27/00 , C07C33/02 , C07C51/00 , C07C59/40 , C07C59/42 , C07C67/00 , C07C69/73 , C07C69/732 , C07C69/734 , C07C213/00 , C07C215/24 , C07C217/46 , C07C219/08 , C07C231/00 , C07C233/02 , C07C235/02 , C07C235/28 , C07C305/14 , C07D295/08 , C07D295/13 , C07D295/14 , C07D295/18 , C07D295/185 , C07D309/12 , C07D317/58 , C07D333/16 , C07D333/24 , C07D335/02 , C07D409/12
CPC分类号: C07D295/185 , C07C305/00 , C07C45/68 , C07C59/42 , C07C69/40 , C07D295/13 , C07D317/58 , Y10S514/927
摘要: Polyprenyl derivatives having the formula ##STR1## [wherein A and B individually represent a group of the formula --CH.sub.2 OR.sup.1 (wherein R.sup.1 is hydrogen atom, an alkyl group having an intervening hetero atom in the carbon chain, carboxyl group on its salt or an aliphatic acyl group optionally having an intervening hetero atom in the carbon chain, an aromatic acyl group, a heterocyclic acyl group, an araliphatic acyl group, a heterocyclic aliphatic acyl group or a radical of an inorganic acid or its salt) or where one of A and B represents the group --CH.sub.2 OR.sup.1, the other represents a group of the formula --COOR.sup.2 (wherein R.sup.2 represents hydrogen atom, a metal atom capable of forming a salt, an organic base or an alkyl group), a group of the formula ##STR2## or a group of the formula ##STR3## (wherein R.sup.3 and R.sup.4 may be the same or different and each represents hydrogen atom, an alkyl group optionally having a heterocyclic substituent, an aryl group or an aralkyl group or R.sup.3 and R.sup.4 may jointly form a ring optionally containing other hetero ring atom) and n is an integer of 0 to 4 inclusive, provided that when both A and B are the group --CH.sub.2 OR.sup.1, either of the R.sup.1 represents an alkyl group having an intervening hetero atom, carboxyl group or its salt, an aliphatic acyl group having an intervening hetero atom in the carbon chain, a heterocyclic acyl group, a heterocyclic aliphatic acyl group or a radical of an inorganic acid or its salt].These derivatives are useful as medicines for treating peptic ulcer.
摘要翻译: 具有式
的聚丙烯衍生物[其中A和B各自表示式-CH 2 OR 1的基团(其中R 1是氢原子,在碳链中具有中间杂原子的烷基,其盐上的羧基或脂族 任选在碳链中具有中间杂原子的酰基,芳族酰基,杂环酰基,芳脂酰基,杂环脂族酰基或无机酸或其盐的基团),或者其中A和 B表示基团-CH 2 OR 1,另一个表示式-COOR 2(其中R 2表示氢原子,能够形成盐的金属原子,有机碱或烷基)的基团,式 或式(IMA)(其中R 3和R 4可以相同或不同,各自表示氢原子,任选具有杂环取代基的烷基,芳基或芳烷基或R 3和R 4可以共同形成 环 任选地含有其它杂环原子),n为0〜4的整数,条件是当A和B都为基团-CH 2 OR 1时,R 1表示具有杂原子的烷基,羧基或其盐 ,在碳链中具有插入杂原子的脂族酰基,杂环酰基,杂环脂族酰基或无机酸或其盐的基团]。 -
公开(公告)号:US08939511B2
公开(公告)日:2015-01-27
申请号:US13576350
申请日:2011-02-15
申请人: Sanji Majima , Ken Kuroiwa , Akira Ogiso , Kiyohiko Kamata , Hiroyuki Nozaki
发明人: Sanji Majima , Ken Kuroiwa , Akira Ogiso , Kiyohiko Kamata , Hiroyuki Nozaki
CPC分类号: B60N2/366 , B60N2/2245
摘要: A first and a second surface of a latch for a seat permit sliding passage of the latch relative to a front leg of a striker, upon contact of the front leg with either of the first and second surfaces. A third surface in a containing space of the latch stops the latch by contacting the front leg. The third surface is arranged such that a rear leg of the striker is brought in alignment with a lock groove of the latch upon contact of the front leg with the third surface. The latch can be guided along the second surface when the second surface contacts the front leg, so that the second surface slides on and past the front leg. By continuously unfolding the seat back upwards until the third surface contacts the front leg, the seat back can be set to a design reference position.
摘要翻译: 当前腿与第一和第二表面中的任一个接触时,用于座位的闩锁的第一和第二表面允许闩锁相对于撞针的前腿滑动通道。 闩锁的容纳空间中的第三表面通过接触前腿而停止闩锁。 第三表面布置成使得当前腿与第三表面接触时,撞针的后腿与闩锁的锁定槽对准。 当第二表面接触前腿时,可以沿着第二表面引导闩锁,使得第二表面在前腿上滑动并经过前腿。 通过将座椅向上延伸展开直到第三表面接触前腿,座椅靠背可被设定为设计参考位置。
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公开(公告)号:US20070259151A1
公开(公告)日:2007-11-08
申请号:US11822854
申请日:2007-07-10
申请人: Akira Ogiso , Hiroyoshi Shiozaki , Tsutomu Ishida , Hisashi Tsukahara , Tsutami Misawa , Koji Inoue , Tadashi Koike , Keiji Ueno , Yuji Inatomi , Ryousuke Nara
发明人: Akira Ogiso , Hiroyoshi Shiozaki , Tsutomu Ishida , Hisashi Tsukahara , Tsutami Misawa , Koji Inoue , Tadashi Koike , Keiji Ueno , Yuji Inatomi , Ryousuke Nara
IPC分类号: B32B3/30
CPC分类号: C09B5/62 , C07F17/00 , C07F17/02 , C09B57/08 , G11B7/244 , G11B7/247 , G11B7/249 , G11B7/2534 , G11B7/2542
摘要: An optical recording medium containing one or more compounds selected from imide compounds having a metallocene residue in a recording layer and an imide compound represented by a general formula (1): wherein a ring AR represents a substituted or unsubstituted aromatic ring residue or a residue formed by combining two or more aromatic ring residues via one or more linking groups; n represents the number of imide groups bonded to the ring AR; Am represents any one of substituents A1 to An bonded to a nitrogen atom of each imide group; and m represents an integer of from 1 to n, with the proviso that at least one substituent selected from the group consisting of A1 to An is one having at least one substituted or unsubstituted metallocene residue.
摘要翻译: 含有一种或多种选自在记录层中具有茂金属残基的酰亚胺化合物和由通式(1)表示的酰亚胺化合物的化合物的光学记录介质:其中环AR表示取代或未取代的芳族环残基或形成的残基 通过一个或多个连接基团组合两个或多个芳族环残基; n表示与环AR结合的酰亚胺基数; A表示与每个酰亚胺基团的氮原子键合的取代基A 1至A n中的任何一个, 并且m表示1至n的整数,条件是至少一个选自A 1至A n的取代基是具有至少一个的取代基 取代或未取代的茂金属残基。
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公开(公告)号:US07259260B2
公开(公告)日:2007-08-21
申请号:US10493034
申请日:2002-10-22
申请人: Akira Ogiso , Hiroyoshi Shiozaki , Tsutomu Ishida
发明人: Akira Ogiso , Hiroyoshi Shiozaki , Tsutomu Ishida
IPC分类号: C07D239/72
CPC分类号: C09B5/62 , C07F17/00 , C07F17/02 , C09B57/08 , G11B7/244 , G11B7/247 , G11B7/249 , G11B7/2534 , G11B7/2542
摘要: An optical recording medium containing one or more compounds selected from imide compounds having a metallocene residue in a recording layer and an imide compound represented by a general formula (1): wherein a ring AR represents a substituted or unsubstituted aromatic ring residue or a residue formed by combining two or more aromatic ring residues via one or more linking groups; n represents the number of imide groups bonded to the ring AR; Am represents any one of substituents A1 to An bonded to a nitrogen atom of each imide group; and m represents an integer of from 1 to n, with the proviso that at least one substituent selected from the group consisting of A1 to An is one having at least one substituted or unsubstituted metallocene residue.
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公开(公告)号:US6132640A
公开(公告)日:2000-10-17
申请号:US877913
申请日:1997-06-18
申请人: Tadashi Okuma , Hideki Ikuta , Tatsuya Nagayoshi , Akira Ogiso , Hisato Ito
发明人: Tadashi Okuma , Hideki Ikuta , Tatsuya Nagayoshi , Akira Ogiso , Hisato Ito
IPC分类号: C07D401/06 , C09B23/04 , C09B57/04 , C09B57/10 , C09K11/06 , H05B33/14 , C07D215/00
CPC分类号: C07D401/06 , C09B23/04 , C09B57/04 , C09B57/10 , C09K11/06 , H05B33/14 , Y10S428/917
摘要: Quinoline compound, zinc halogenide complex and zinc complex suited for use in an electro-luminescence (EL) element, a fluorescent material and an ultraviolet absorption material, and a preparation process for these compounds are described. These compounds and a tautomer of the same have a strong luminescent intensity and are used for an EL material, the compound of zinc halogenide complex and zinc complex and a tautomer of the same has absorption at a wave length of 400 nm or less and is used for an ultraviolet absorption material, and further the quinoline compound and a tautomer has a strong luminescent intensity and is used for a fluorescent material. The zinc halogenide complex and zinc complex can be prepared by related preparation processes directly from a quinoline derivative and a phthalimide derivative, or by way of the quinoline compound which is obtained from these derivatives.
摘要翻译: 描述适用于电致发光(EL)元件,荧光材料和紫外线吸收材料的喹啉化合物,卤化锌络合物和锌络合物以及这些化合物的制备方法。 这些化合物及其互变异构体具有强的发光强度,并且用于EL材料,卤化锌络合物和锌络合物的化合物及其互变异构体在400nm或更小的波长处具有吸收,并且被使用 对于紫外线吸收材料,此外,喹啉化合物和互变异构体具有强的发光强度并用于荧光材料。 卤化锌络合物和锌络合物可以通过直接来自喹啉衍生物和邻苯二甲酰亚胺衍生物的相关制备方法或通过由这些衍生物获得的喹啉化合物制备。
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