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公开(公告)号：US10018552B2
公开(公告)日：2018-07-10
申请号：US15210158
申请日：2016-07-14
Applicant: NIKON CORPORATION
Inventor： Daishi Tanaka , Hisao Osawa , Kuno Suzuki
CPC classification number: G01N15/1459 , G01N15/00 , G01N15/1463 , G01N15/1468 , G01N21/53 , G01N27/44721 , G01N2015/0003 , G01N2015/0038 , G01N2015/0065 , G01N2015/1075 , G01N2021/473 , G01N2021/4797 , G01N2201/12
Abstract: A particle analysis apparatus includes: an acquisition unit that acquires a plurality of images each captured at a different time in each of which a particle moving in a predetermined direction in a medium is imaged; and a determination unit that determines, based on a movement amount of a particle due to Brownian motion in the medium, whether or not an image of a first particle included in an image captured at a first time of the plurality of images acquired by the acquisition unit and an image of a second particle included in an image captured at a second time which is different from the first time of the plurality of images acquired by the acquisition unit are images indicating the same particle.
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Patent Agency Ranking
公开(公告)号：US10301170B2
公开(公告)日：2019-05-28
申请号：US15392916
申请日：2016-12-28
Applicant: The University of Tokyo , NIKON CORPORATION
Inventor： Takanori Ichiki , Shoutarou Terane , Kuno Suzuki
Abstract: A valve is provided with a tubular structure having an outer tube and an inner tube, and a diaphragm member having a thin film disposed to cover one end of the inner tube and an anchor part which encircles a peripheral edge of the thin film and comes into close contact with an inner wall of the outer tube and an outer wall of the inner tube.
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公开(公告)号：US10295454B2
公开(公告)日：2019-05-21
申请号：US15786450
申请日：2017-10-17
Applicant: The University of Tokyo , NIKON CORPORATION
Inventor： Takanori Ichiki , Kuno Suzuki , Daishi Tanaka
Abstract: A microparticle detection system includes a stage unit including a mounting surface on which a fluid device having a flow path through which a sample containing microparticles is movable is capable of being mounted, an emission unit configured to emit illumination light to the flow path, an imaging unit configured to image scattered light generated from microparticles in the sample when illumination light is emitted, an identification unit configured to identify the microparticles included in the image for each of the microparticles on the basis of the image captured by the imaging unit, a particle size determination unit configured to determine a particle size of the microparticle for each of the microparticles identified by the identification unit, a zeta potential determination unit configured to determine a zeta potential of the microparticle for each of the microparticles identified by the identification unit, and a correlation unit configured to associate the particle size for each of the microparticles determined by the particle size determination unit with the zeta potential for each of the microparticles determined by the zeta potential determination unit for each of the microparticles.
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公开(公告)号：US10100939B2
公开(公告)日：2018-10-16
申请号：US15172453
申请日：2016-06-03
Applicant: The University of Tokyo , Nikon Corporation
Inventor： Takanori Ichiki , Masashi Kobayashi , Shotaro Terane , Kuno Suzuki
Abstract: A valve disposed at a flow path includes: a substrate having a first surface in which a hole having an opening section is formed; and a diaphragm member fixed to at least part of a wall surface of the hole and in which at least a central portion has a thin film shape, wherein a flow of a fluid in the flow path is controlled by deforming the diaphragm member.
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公开(公告)号：US10113948B2
公开(公告)日：2018-10-30
申请号：US15490727
申请日：2017-04-18
Applicant: The University of Tokyo , NIKON CORPORATION
Inventor： Takanori Ichiki , Kuno Suzuki , Daishi Tanaka , Jiro Inoue , Kazuya Ota
Abstract: A particle detection method in which particles in a sample are detected includes: a mounting step of mounting, on a stage portion, a fluid device including a channel through which the particles can move; an irradiation step of irradiating the channel with illumination light; and a detection step of detecting scattered light generated from the particles by irradiation with the illumination light. In the irradiation step, the illumination light is converged such as to enter the channel by passing through, among side surfaces of the channel, only the first side surface that faces an illumination light incident direction.
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公开(公告)号：US20180100793A1
公开(公告)日：2018-04-12
申请号：US15786450
申请日：2017-10-17
Applicant: The University of Tokyo , Nikon Corporation
Inventor： Takanori Ichiki , Kuno Suzuki , Daishi Tanaka
CPC classification number: G01N15/14 , G01N15/02 , G01N15/0227 , G01N15/1429 , G01N15/1484 , G01N27/26 , G01N33/53 , G01N2015/0053 , G01N2015/1006 , G01N2015/1075 , G01N2015/1486 , G01N2015/1493
Abstract: A microparticle detection system includes a stage unit including a mounting surface on which a fluid device having a flow path through which a sample containing microparticles is movable is capable of being mounted, an emission unit configured to emit illumination light to the flow path, an imaging unit configured to image scattered light generated from microparticles in the sample when illumination light is emitted, an identification unit configured to identify the microparticles included in the image for each of the microparticles on the basis of the image captured by the imaging unit, a particle size determination unit configured to determine a particle size of the microparticle for each of the microparticles identified by the identification unit, a zeta potential determination unit configured to determine a zeta potential of the microparticle for each of the microparticles identified by the identification unit, and a correlation unit configured to associate the particle size for each of the microparticles determined by the particle size determination unit with the zeta potential for each of the microparticles determined by the zeta potential determination unit for each of the microparticles.
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