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公开(公告)号:US10343165B2
公开(公告)日:2019-07-09
申请号:US15396175
申请日:2016-12-30
发明人: Amir Sadri , Kun Guo , Daniel Y. Chu , Nenad Kircanski , Paul J. Patt , Tal Rosenzweig
摘要: Systems, including apparatus and methods, for the microfluidic manipulation, dispensing, and/or sorting of particles, such as cells and/or beads.
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公开(公告)号:US11690169B2
公开(公告)日:2023-06-27
申请号:US17841931
申请日:2022-06-16
发明人: Amir Sadri , Neven Nikolic , Gabriel Culinco , Thanh-Vi Tran , Nenad Kircanski
CPC分类号: H05K1/0272 , H05K7/20145 , H05K7/20163 , H05K7/20209 , H05K2201/064 , H05K2201/066
摘要: A thermal management system that include an electronic circuit boards having at least two circuit boards with a space in between and further includes one or more air tubes or conduits. The electronic circuit board and air tubes are configured for drawing air into the space to facilitate cooling of the electronic circuit board concurrent with cooling of a heat sink of a heat pump connected with the electronic circuit board. The system can further include a partition to isolate airflow from the heat sink from airflow through the electronics circuit board, and can further include one or more interface components for maintaining isolation and control of air flow, improving air intake and/or supporting auxiliary components.
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公开(公告)号:US20200224936A1
公开(公告)日:2020-07-16
申请号:US16733155
申请日:2020-01-02
发明人: Amir Sadri , Nenad Kircanski , Thanh-Vi Tran , Carl Marlowe , Brian David Wilson
摘要: A heat pump that includes a thermoelectric device(s) and a heat sink having a raised portion with a top surface for thermally coupling with a planar face of the thermoelectric device(s). The raised portion of the heat sink includes an outer periphery and a raised central region surrounded by a void region to provide more uniform thermal conductivity when clamped within an assembly. The raised central region is shaped in an any shape corresponding to a shape of uneven thermal conductivity due to clamping pressure applied to the heat sink. The void region can be substantially contiguous and entirely circumscribe the central raised region. The device can optionally include discrete supports formed of a less thermally-conductive material within the void region. The supports can be elastomeric, such as O-rings, and disposed within pockets defined within the void region.
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公开(公告)号:US20170225363A1
公开(公告)日:2017-08-10
申请号:US15503360
申请日:2015-08-28
发明人: Daniel Konstantinou , Alwin Wan , Tal Rosenzweig , Amir Sadri , Nenad Kircanski , Edmond Young
摘要: A method for efficiently manufacturing and fabricating microfluidic chips, where a base mold is formed to have positive-relief features used to cast an intermediary template chip with negative-relief features having dimensions of a scale in the micron range. The intermediary template chip is used to case a production mold, which is formed of a reinforced epoxy resin that, once hardened into a solid epoxy member, can withstand the structural pressures of a CNC machining system. The production mold can be refined by a CNC machining, where the refined production mold is then used to cast production chips to be used as microfluidic chips.
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公开(公告)号:US20170297019A1
公开(公告)日:2017-10-19
申请号:US15508027
申请日:2015-08-25
发明人: Alwin Wan , Amir Sadri , Tal Rosenzweig , Nenad Kircanski , Edmond Young
摘要: Microscale fluidic devices and components thereof having a fluid retention groove, as well as systems and methods related thereto. The fluid retention groove facilitates uniform bonding of microfluidic device components.
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公开(公告)号:US20170128941A1
公开(公告)日:2017-05-11
申请号:US15396175
申请日:2016-12-30
发明人: Amir Sadri , Kun Guo , Daniel Y. Chu , Nenad Kircanski , Paul J. Patt , Tal Rosenzweig
CPC分类号: B01L3/502761 , B01L3/0265 , B01L3/502738 , B01L3/502776 , B01L2200/027 , B01L2200/0652 , B01L2200/0689 , B01L2200/12 , B01L2200/146 , B01L2200/147 , B01L2200/16 , B01L2300/021 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0864 , B01L2300/088 , B01L2300/0887 , B01L2300/123 , B01L2300/16 , B01L2300/165 , B01L2300/18 , B01L2400/0406 , B01L2400/0409 , B01L2400/0415 , B01L2400/0457 , B01L2400/0487 , B01L2400/0644 , B01L2400/065 , B01L2400/0655 , B01L2400/0688 , B01L2400/082 , B01L2400/084 , C12Q1/24 , G01N15/1056 , G01N15/1404 , G01N15/1484 , G01N2015/1006 , G01N2015/1081 , G01N2015/1413 , G01N2015/149 , Y10T436/25 , Y10T436/25375
摘要: Systems, including apparatus and methods, for the microfluidic manipulation, dispensing, and/or sorting of particles, such as cells and/or beads.
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公开(公告)号:US11892205B2
公开(公告)日:2024-02-06
申请号:US17989938
申请日:2022-11-18
发明人: Amir Sadri , Nenad Kircanski , Thanh-Vi Tran , Carl Marlowe , Brian David Wilson
CPC分类号: F25B21/04 , B01L7/00 , B01L7/52 , H10N10/10 , H10N10/80 , B01L2300/08 , B01L2300/123 , B01L2300/1805
摘要: A heat pump that includes a thermoelectric device(s) and a heat sink having a raised portion with a top surface for thermally coupling with a planar face of the thermoelectric device(s). The raised portion of the heat sink includes an outer periphery and a raised central region surrounded by a void region to provide more uniform thermal conductivity when clamped within an assembly. The raised central region is shaped in an any shape corresponding to a shape of uneven thermal conductivity due to clamping pressure applied to the heat sink. The void region can be substantially contiguous and entirely circumscribe the central raised region. The device can optionally include discrete supports formed of a less thermally-conductive material within the void region. The supports can be elastomeric, such as O-rings, and disposed within pockets defined within the void region.
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公开(公告)号:US11549731B2
公开(公告)日:2023-01-10
申请号:US16733155
申请日:2020-01-02
发明人: Amir Sadri , Nenad Kircanski , Thanh-Vi Tran , Carl Marlowe , Brian David Wilson
摘要: A heat pump that includes a thermoelectric device(s) and a heat sink having a raised portion with a top surface for thermally coupling with a planar face of the thermoelectric device(s). The raised portion of the heat sink includes an outer periphery and a raised central region surrounded by a void region to provide more uniform thermal conductivity when clamped within an assembly. The raised central region is shaped in an any shape corresponding to a shape of uneven thermal conductivity due to clamping pressure applied to the heat sink. The void region can be substantially contiguous and entirely circumscribe the central raised region. The device can optionally include discrete supports formed of a less thermally-conductive material within the void region. The supports can be elastomeric, such as O-rings, and disposed within pockets defined within the void region.
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公开(公告)号:US11375612B2
公开(公告)日:2022-06-28
申请号:US17102027
申请日:2020-11-23
发明人: Amir Sadri , Neven Nikolic , Gabriel Culinco , Thanh-Vi Tran , Nenad Kircanski
摘要: A thermal management system that include an electronic circuit boards having at least two circuit boards with a space in between and further includes one or more air tubes or conduits. The electronic circuit board and air tubes are configured for drawing air into the space to facilitate cooling of the electronic circuit board concurrent with cooling of a heat sink of a heat pump connected with the electronic circuit board. The system can further include a partition to isolate airflow from the heat sink from airflow through the electronics circuit board, and can further include one or more interface components for maintaining isolation and control of air flow, improving air intake and/or supporting auxiliary components.
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公开(公告)号:US10682789B2
公开(公告)日:2020-06-16
申请号:US15503360
申请日:2015-08-28
发明人: Daniel Konstantinou , Alwin Wan , Tal Rosenzweig , Amir Sadri , Nenad Kircanski , Edmond Young
IPC分类号: B29C33/40 , B29C33/42 , B29C33/38 , B01L3/00 , B29C39/00 , B29C39/02 , B29C59/02 , B29K33/00
摘要: A method for efficiently manufacturing and fabricating microfluidic chips, where a base mold is formed to have positive-relief features used to cast an intermediary template chip with negative-relief features having dimensions of a scale in the micron range. The intermediary template chip is used to case a production mold, which is formed of a reinforced epoxy resin that, once hardened into a solid epoxy member, can withstand the structural pressures of a CNC machining system. The production mold can be refined by a CNC machining, where the refined production mold is then used to cast production chips to be used as microfluidic chips.
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