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    EGLN2 VARIANTS AND USE THEREOF IN PREVENTING OR TREATING THROMBOEMBOLIC DISORDERS AND CORONARY HEART DISEASES
    2.
    发明申请
    EGLN2 VARIANTS AND USE THEREOF IN PREVENTING OR TREATING THROMBOEMBOLIC DISORDERS AND CORONARY HEART DISEASES 失效
    EGLN2变异体及其在预防或治疗血栓性疾病和冠状动脉疾病中的应用

    公开(公告)号：US20110123515A1

    公开(公告)日：2011-05-26

    申请号：US13015994

    申请日：2011-01-28

    Applicant: Detlef KOZIAN ,  Matthias HERRMANN

    Inventor： Detlef KOZIAN ,  Matthias HERRMANN

    IPC: A61K38/46 ,  C12Q1/68 ,  C12Q1/26 ,  C40B30/06 ,  C40B30/00

    CPC classification number: C12N9/0071

    Abstract: The present invention refers to human EGLN2 variants having at position 58 of the amino acid sequence a serine or a leucine and their use in the prevention or treatment of thromboembolic or coronary heart diseases, in particular stroke, prolonged reversible ischemic neurological deficit (PRIND), transitoric ischemic attack (TIA), myocardial infarction and/or early myocardial infarction.

    Abstract translation: 本发明涉及具有丝氨酸或亮氨酸的氨基酸序列58位的人EGLN2变异体及其在预防或治疗血栓栓塞或冠心病，特别是中风，长期可逆性缺血性神经功能缺损（PRIND）， 经皮缺血发作（TIA），心肌梗死和/或早期心肌梗死。

    INJECTION VALVE, METHOD FOR ITS PRODUCTION, AND APPARATUS FOR PERFORMING THE METHOD
    3.
    发明申请
    INJECTION VALVE, METHOD FOR ITS PRODUCTION, AND APPARATUS FOR PERFORMING THE METHOD 有权
    注射阀，其制造方法以及用于执行该方法的装置

    公开(公告)号：US20100180442A1

    公开(公告)日：2010-07-22

    申请号：US12666190

    申请日：2008-06-17

    Applicant: Bernhard Zeiss ,  Wilhelm Christ ,  Ralf Kuebler ,  Alfred Hoch ,  Matthias Herrmann ,  Lars Ulrich

    Inventor： Bernhard Zeiss ,  Wilhelm Christ ,  Ralf Kuebler ,  Alfred Hoch ,  Matthias Herrmann ,  Lars Ulrich

    IPC: B21K1/24 ,  B21D51/16

    CPC classification number: F02M61/168 ,  B21K1/24 ,  C21D1/10 ,  C21D1/18 ,  C21D1/25 ,  F02M61/18 ,  F02M2200/02 ,  F02M2200/9061 ,  Y02P10/253 ,  Y10T29/49405 ,  Y10T29/49409

    Abstract: The invention relates to a method for producing an injection valve for liquids, preferably an injection valve for injecting fuel into a combustion chamber of an internal combustion engine. The injection valve has a valve body, with a valve seat which is formed therein, and a valve needle which interacts with the valve seat in order to open and close at least one injection opening. The injection valve is produced by means of the following method steps: producing the valve body from steel, hardening the valve body, annealing a partial region of the valve body at an annealing temperature. The device for carrying out the method according to the invention has an inductive annealing generator which generates a suitable alternating current for operating a coil, in the magnetic field of which coil the valve body can be heated for annealing.

    Abstract translation: 本发明涉及一种用于生产用于液体的喷射阀的方法，优选地是用于将燃料喷射到内燃机的燃烧室中的喷射阀。 喷射阀具有形成有阀座的阀体和与阀座相互作用以打开和关闭至少一个喷射开口的阀针。 注射阀通过以下方法步骤制造：从钢制造阀体，硬化阀体，在退火温度下退火阀体的局部区域。 用于执行根据本发明的方法的装置具有感应退火发生器，其产生用于操作线圈的合适的交流电流，在该磁体的磁场中，阀体可以被加热用于退火。

    Method of Diagnosis of a Predisposition to Develop Thrombotic Disease and Its Uses
    5.
    发明申请
    Method of Diagnosis of a Predisposition to Develop Thrombotic Disease and Its Uses 失效
    诊断血栓形成疾病倾向的方法及其应用

    公开(公告)号：US20080038722A1

    公开(公告)日：2008-02-14

    申请号：US10592692

    申请日：2005-03-16

    Applicant: Detlef Kozian ,  Matthias Herrmann ,  Jean-Francois Deleuze ,  Sylvain Ricard ,  Sandrine Mace

    Inventor： Detlef Kozian ,  Matthias Herrmann ,  Jean-Francois Deleuze ,  Sylvain Ricard ,  Sandrine Mace

    IPC: C12Q1/68

    CPC classification number: C12Q1/6883 ,  C12Q2600/156

    Abstract: The present invention refers to a method of diagnosis of a predisposition to develop thrombotic disease, to test systems and their use for the diagnosis of a predisposition to develop thrombotic disease, to a P2X1 promoter variant and its use for screening for an anti-thrombotic agent, and to methods for identifying an individual that can be prophylactically or therapeutically treated with an anti-thrombotic agent, or for adapting a therapeutic or prophylactic dose of an anti-thrombotic agent.

    Abstract translation: 本发明涉及诊断发生血栓形成疾病的倾向，测试系统及其用于诊断倾向于发展血栓形成性疾病的用途的方法，以诊断P 启动子变体及其用于筛选抗血栓形成剂的用途，以及用于鉴定可以用抗血栓形成剂预防性或治疗性治疗的个体的方法，或用于调整治疗或预防剂量的抗血栓形成剂 血栓形成剂。

    Circuit arrangement for deriving signals for masking audio signals
    7.
    发明授权
    Circuit arrangement for deriving signals for masking audio signals 失效
    用于导出用于屏蔽音频信号的信号的电路布置

    公开(公告)号：US5661810A

    公开(公告)日：1997-08-26

    申请号：US522314

    申请日：1995-08-25

    Applicant: Djahanyar Chahabadi ,  Matthias Herrmann ,  Lothar Vogt ,  Jurgen Kaesser

    Inventor： Djahanyar Chahabadi ,  Matthias Herrmann ,  Lothar Vogt ,  Jurgen Kaesser

    IPC: H03H17/04 ,  H03H17/02 ,  H04B1/10 ,  H04B1/16 ,  H04B1/26 ,  H04B1/64 ,  H04H1/00 ,  H04H20/57 ,  H04H40/63 ,  H04H40/72 ,  H04H5/00

    CPC classification number: H04H40/63 ,  H04H40/72 ,  H04H20/57

    Abstract: The circuit arrangement includes a first low-pass filter (2) for filtering an input signal (H3) proportional to the strength of a received radio signal; a second low-pass filter (3) for filtering the input signal (H3); a first weighting circuit (7) for weighting the first low-pass filter output signal with first coefficients to form a first weighted output signal; a circuit device for forming a masking signal for reducing stereo channel isolation from the first weighted output signal; a second weighting circuit (5) for forming a second weighted output signal weighted with second coefficients from the first low-pass filter output signal or the second low-pass filter output signal according to a switching signal (DD2) indicative of interference in the audio signals; a switch device (4) for selecting the first low-pass filter output signal for weighting in the second weighting circuit means (5) when no interference is indicated by the switching signal (DD2) and the second low-pass filter output signal for weighting in the second weighting circuit means (5) when interference is indicated by the switching signal (DD2); and a circuit device for forming a masking signal for damping the audio signal from the second weighted output signal.

    Abstract translation: PCT No.PCT / DE94 / 00321 Sec。 371日期1995年8月25日 102（e）日期1995年8月25日PCT 1994年3月22日PCT公布。 公开号WO94 / 22229 日期1995年9月29日该电路装置包括：第一低通滤波器（2），用于对与接收的无线电信号的强度成正比的输入信号（H3）进行滤波; 用于对输入信号（H3）进行滤波的第二低通滤波器（3）; 第一加权电路（7），用于利用第一系数对第一低通滤波器输出信号进行加权，以形成第一加权输出信号; 电路装置，用于形成用于减少立体声信道隔离的屏蔽信号与第一加权输出信号; 第二加权电路（5），用于根据指示音频中的干扰的切换信号（DD2），从第一低通滤波器输出信号或第二低通滤波器输出信号形成用第二系数加权的第二加权输出信号 信号; 开关装置（4），用于当没有由开关信号（DD2）指示干扰和用于加权的第二低通滤波器输出信号时，在第二加权电路装置（5）中选择用于加权的第一低通滤波器输出信号 在第二加权电路装置（5）中，当由切换信号（DD2）指示干扰时; 以及电路装置，用于形成用于阻尼来自第二加权输出信号的音频信号的屏蔽信号。

    Radio receiver having digital signal processing
    8.
    发明授权
    Radio receiver having digital signal processing 失效
    具有数字信号处理的无线电接收机

    公开(公告)号：US5661809A

    公开(公告)日：1997-08-26

    申请号：US343413

    申请日：1995-02-14

    Applicant: Djahanyar Chahabadi ,  Matthias Herrmann ,  Lothar Vogt ,  Juergen Kaesser

    Inventor： Djahanyar Chahabadi ,  Matthias Herrmann ,  Lothar Vogt ,  Juergen Kaesser

    IPC: H03H17/04 ,  H03H17/02 ,  H04B1/10 ,  H04B1/16 ,  H04B1/26 ,  H04B1/30 ,  H04B1/64 ,  H04H20/88 ,  H04H5/00

    CPC classification number: H04B1/1661 ,  H04B1/1027

    Abstract: A radio receiver is provided having digital signal processing, a first and a second auxiliary signal derived from a received stereo multiplex signal, the first auxiliary signal being dependent upon the existence of signal components, whose frequency lies above the fundamental frequency range of the stereo multiplex signal, and the second auxiliary signal being dependent upon the symmetry of the sidebands of the stereo subcarrier. The first and the second auxiliary signal are combined to form an interference signal indicating the existence of interference. At least one control signal is derived from the interference signal to influence the audio signals acquired by decoding the stereo multiplex signal.

    Abstract translation: PCT No.PCT / DE94 / 00324 Sec。 371日期：1995年2月14日 102（e）日期1995年2月14日PCT 1994年3月22日PCT公布。 公开号WO94 / 22231 日期1994年9月29日提供具有数字信号处理的无线电接收机，从接收的立体声多路复用信号导出的第一和第二辅助信号，第一辅助信号取决于信号分量的存在，其频率高于基频 立体声多路复用信号的范围，第二辅助信号取决于立体声副载波的边带的对称性。 第一和第二辅助信号被组合以形成指示干扰的存在的干扰信号。 从干扰信号导出至少一个控制信号，以影响通过解码立体声多路复用信号而获得的音频信号。

    Circuit for digital processing of audio signals
    9.
    发明授权
    Circuit for digital processing of audio signals 失效
    音频信号数字处理电路

    公开(公告)号：US5491755A

    公开(公告)日：1996-02-13

    申请号：US183029

    申请日：1994-01-18

    Applicant: Lothar Vogt ,  Matthias Herrmann

    Inventor： Lothar Vogt ,  Matthias Herrmann

    IPC: H03G3/02 ,  H03G5/00 ,  H03G9/00 ,  H03H17/00 ,  H03H17/02 ,  H04B1/00

    CPC classification number: H03G5/005

    Abstract: In a circuit for digital processing of audio signals in a radio receiver, preferably in a car radio, the audio signals pass through a digital filter designed as a tone control, whose frequency response can be controlled with supplied coefficients, and a volume control, whose transmission factor can be controlled with supplied control signals. If the high and/or low frequencies are raised, the transmission factor of the filter at medium frequencies can be correspondingly lowered. Volume control compensates for the reduction. The volume control may contain a digital and an analog portion.

    Abstract translation: 在无线电接收机，优选在汽车无线电中的音频信号的数字处理电路中，音频信号通过设计成音调控制的数字滤波器，其频率响应可以用所提供的系数来控制，音量控制器 传输系数可以通过提供的控制信号进行控制。 如果提高高频和/或低频，则可以相应地降低中频滤波器的传输系数。 音量控制补偿减少。 音量控制可以包含数字和模拟部分。

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