公开(公告)号：US20150038475A1

公开(公告)日：2015-02-05

申请号：US14500438

申请日：2014-09-29

申请人： Basawaraj Chickmath ,  Chandrashekar Giliyar ,  Chidambaram Nachiappan ,  Mahesh Patel ,  Srinivasan Venkateshwaran

发明人： Basawaraj Chickmath ,  Chandrashekar Giliyar ,  Chidambaram Nachiappan ,  Mahesh Patel ,  Srinivasan Venkateshwaran

IPC分类号： A61K9/20 ,  A61K47/10 ,  A61K47/36 ,  A61K31/568

CPC分类号： A61K9/2031 ,  A61K9/14 ,  A61K9/146 ,  A61K9/148 ,  A61K9/1652 ,  A61K9/1676 ,  A61K9/1694 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/205 ,  A61K9/2054 ,  A61K9/282 ,  A61K9/2853 ,  A61K9/286 ,  A61K9/2866 ,  A61K9/4866 ,  A61K9/4875 ,  A61K31/568 ,  A61K47/10 ,  A61K47/36 ,  A61K47/38 ,  A61K47/40

摘要： The present disclosure is drawn to pharmaceutical compositions and oral dosage forms containing testosterone undecanoate, as well as related methods of treatment. In one embodiment, the oral dosage form can include a therapeutically effective amount of testosterone undecanoate and a pharmaceutically acceptable carrier. The dosage form can be formulated such that, when measured using a USP Type II apparatus in 1000 mL of 8 wt % Triton X-100 in water at 37° C. and 100 rpm, the oral dosage form releases at least 20% more testosterone undecanoate after the first 120 minutes than an equivalent dose testosterone undecanoate containing oral dosage form without the pharmaceutically acceptable carrier.

摘要翻译： 本公开涉及含有十一酸睾酮的药物组合物和口服剂型，以及相关的治疗方法。 在一个实施方案中，口服剂型可以包括治疗有效量的十一酸睾酮和药学上可接受的载体。 可以配制剂型，使得当使用USP II型装置在1000mL的8重量％Triton X-100在水中在37℃和100rpm下测量时，口服剂型释放至少20％以上的睾酮 十一酸十一酸酯比不含药学上可接受的载体的含有口服剂型的等效剂量十一酸睾酮。

公开(公告)号：US20100177680A1

公开(公告)日：2010-07-15

申请号：US12351048

申请日：2009-01-09

申请人： Larry G. Fischer ,  Jamie Brown ,  Mahesh Patel ,  Tony Lefebvre

发明人： Larry G. Fischer ,  Jamie Brown ,  Mahesh Patel ,  Tony Lefebvre

IPC分类号： H04W4/00

CPC分类号： H04L67/2842 ,  H04L65/1026

摘要： A wireless network comprises a plurality of areas of interest and a core network coupled to each of the plurality of areas of interest to route real-time data from each of the plurality of areas of interest. Each of the plurality of areas of interest includes a plurality of wireless communication units. Each wireless communication unit comprises a local cache to store non-real-time data; and a gateway to process non-real-time data requests and provide an interface to a packet network. The plurality of wireless communication units in each of the plurality of areas of interest are networked together such that each wireless communication unit has access to data stored on the local cache of another of the plurality of wireless communication units, wherein the gateway in each of the plurality of wireless communication units is operable to provide the requested non-real-time data, if available, from one of its local cache and the cache of other wireless communication units prior to passing the non-real-time data request to the packet network.

摘要翻译： 无线网络包括多个感兴趣的区域和耦合到所述多个感兴趣区域中的每一个的核心网络以从多个感兴趣区域中的每一个区域路由实时数据。 多个感兴趣区域中的每一个包括多个无线通信单元。 每个无线通信单元包括本地高速缓存以存储非实时数据; 以及用于处理非实时数据请求并向分组网络提供接口的网关。 多个感兴趣区域中的每一个中的多个无线通信单元被联网在一起，使得每个无线通信单元能够访问存储在多个无线通信单元中的另一个的本地高速缓存上的数据，其中每个 多个无线通信单元可操作以在将非实时数据请求传递到分组网络之前提供所请求的非实时数据（如果可用）从其本地高速缓存和其它无线通信单元的高速缓存提供 。

公开(公告)号：US20060261000A1

公开(公告)日：2006-11-23

申请号：US11429711

申请日：2006-05-08

申请人： Laurence Bassett ,  William Contaxis ,  Karl Fritze ,  Mahesh Patel

发明人： Laurence Bassett ,  William Contaxis ,  Karl Fritze ,  Mahesh Patel

IPC分类号： B01D35/28

CPC分类号： B01D39/2079 ,  B01D35/30 ,  B01D39/1661 ,  B01D2201/02 ,  B01D2201/302 ,  B01D2201/4015 ,  C02F1/001 ,  C02F1/283 ,  C02F2201/006

摘要： A filter cartridge includes a one-piece housing having a port and a filtration element disposed in the housing. The filtration element is a coherent filter block that can be, but is not necessarily, larger in cross dimension than the port. In one embodiment, the filtration element is a coherent filter block that generally conforms to the shape of the hollow interior, but is slightly smaller than the hollow interior so as to define a gap between the filtration element and the inner surface. One method for constructing a filter cartridge includes providing a housing having a hollow interior and at least one port, introducing a granular material into the hollow interior via the port, and transforming the granular material in the hollow material into a coherent filter block. Another method for constructing a filter cartridge includes providing a filtration element in the form of a coherent filter block, and overmolding a housing around the filtration element.

摘要翻译： 滤筒包括具有端口的一体式壳体和设置在壳体中的过滤元件。 过滤元件是相干过滤器块，其可以但并不一定比端口的交叉尺寸更大。 在一个实施例中，过滤元件是通常符合中空内部形状但是略小于中空内部的相干过滤块，以便限定过滤元件和内表面之间的间隙。 一种用于构造过滤器滤芯的方法包括提供具有中空内部和至少一个端口的壳体，通过该端口将颗粒材料引入中空内部，并将中空材料中的颗粒材料转化为相干过滤块。 用于构造过滤器滤芯的另一种方法包括提供呈粘性过滤块形式的过滤元件，以及围绕过滤元件的壳体包覆模制。

公开(公告)号：US20060060512A1

公开(公告)日：2006-03-23

申请号：US11267670

申请日：2005-11-04

申请人： Robert Astle ,  Hemang Patel ,  Mahesh Patel ,  Thomas Holler ,  Karl Fritze

发明人： Robert Astle ,  Hemang Patel ,  Mahesh Patel ,  Thomas Holler ,  Karl Fritze

IPC分类号： B01D35/143

CPC分类号： B01D35/143 ,  B01D27/101 ,  B01D29/606 ,  B01D2201/4023 ,  B01D2201/4046 ,  B01D2201/52 ,  B01D2201/54 ,  B01D2201/56 ,  C02F9/005 ,  C02F2201/006 ,  C02F2209/008 ,  C02F2209/40 ,  C02F2209/42

摘要： A fluid treatment system is provided, the system including a fluid treatment cartridge for treating fluid passing therethrough. The cartridge has an inlet through which untreated fluid enters the cartridge and an outlet from which treated fluid exits the cartridge. The cartridge also has a radio frequency identification (RFID) tag for storing data. The fluid treatment system also includes a connection manifold configured to detachably support the fluid treatment cartridge. The connection manifold has an inlet flow path for directing untreated fluid to the inlet of the cartridge and an outlet flow path for directing treated fluid from the outlet of the cartridge, and a data sensor for reading data stored on the RFID tag. The fluid treatment system further includes means for evaluating the data stored on the RFID tag and read by the data sensor, as well as means for deterring fluid treatment system use based upon the evaluation of the data stored on the RFID tag and read by the data sensor.

摘要翻译： 提供了一种流体处理系统，该系统包括用于处理通过其中的流体的流体处理盒。 药筒具有未经处理的流体进入药筒的入口和经处理的流体从出口离开药筒的出口。 该盒还具有用于存储数据的射频识别（RFID）标签。 流体处理系统还包括配置成可拆卸地支撑流体处理盒的连接歧管。 连接歧管具有用于将未处理的流体引导到药筒的入口的入口流动路径和用于引导来自药筒的出口的经处理的流体的出口流动路径，以及用于读取存储在RFID标签上的数据的数据传感器。 流体处理系统还包括用于评估存储在RFID标签上并由数据传感器读取的数据的装置，以及用于基于对存储在RFID标签上的数据的评估并通过数据读取来阻止流体处理系统使用的装置 传感器。

公开(公告)号：US20050143421A1

公开(公告)日：2005-06-30

申请号：US10935708

申请日：2004-09-07

申请人： Prasad Deshpande ,  Milind Sindkhedkar ,  Mahesh Phansalkar ,  Ravindra Yeole ,  Shrikant Gupte ,  Yati Chugh ,  Nitin Shetty ,  Sachin Bhagwat ,  Milind Shukla ,  Noel De Souza ,  Mahesh Patel

发明人： Prasad Deshpande ,  Milind Sindkhedkar ,  Mahesh Phansalkar ,  Ravindra Yeole ,  Shrikant Gupte ,  Yati Chugh ,  Nitin Shetty ,  Sachin Bhagwat ,  Milind Shukla ,  Noel De Souza ,  Mahesh Patel

IPC分类号： C07D413/10 ,  C07D413/14 ,  C07D491/10 ,  C07D495/10 ,  C07D497/10 ,  C07D498/10 ,  C07D513/10 ,  C07D413/02 ,  A61K31/422 ,  A61K31/454

CPC分类号： C07D491/10 ,  C07D413/10 ,  C07D413/14 ,  C07D495/10 ,  C07D497/10 ,  C07D513/10

摘要： The present invention provides agents having antimicrobial activity for preventing and treating infectious diseases. Thus, the present invention provides novel substituted piperidino phenyloxazolidinone derivatives, processes for making compounds as well as antimicrobial compositions containing said derivatives as active ingredients and methods of treating bacterial infections with the said derivatives.

摘要翻译： 本发明提供具有预防和治疗感染性疾病的抗微生物活性的试剂。 因此，本发明提供新的取代的哌啶子基苯基恶唑烷酮衍生物，制备化合物的方法以及含有所述衍生物作为活性成分的抗微生物组合物以及用所述衍生物治疗细菌感染的方法。

公开(公告)号：US06770819B2

公开(公告)日：2004-08-03

申请号：US10074741

申请日：2002-02-12

申请人： Mahesh Patel

发明人： Mahesh Patel

IPC分类号： H01B1104

CPC分类号： H01B11/005

摘要： A communications cable comprises an elongate cable jacket having an internal cavity and a plurality of twisted pairs of insulated conductors disposed in the internal cavity of the cable jacket, each of the conductors being insulated with a polymeric layer. Each of the insulated conductors within each of the twisted pairs of conductors defines a twinning helix having a first rotative direction, and each of the twisted pairs defines a bunching helix having a second rotative direction, the second rotative direction being opposite that of the first rotative direction. In this configuration, the communications cable can provide acceptable crosstalk and attenuation performance, even with foamed insulators that have demonstrated unacceptable performance when twinned and bunched in the same rotative direction.

摘要翻译： 通信电缆包括细长的电缆护套，其具有设置在电缆护套的内部空腔中的内部空腔和多个绝缘导体的双绞线，每个导体与聚合物层绝缘。 每个绞合线对中的每个绝缘导体限定具有第一旋转方向的孪生螺旋，并且每个双绞线限定具有第二旋转方向的聚束螺旋，第二旋转方向与第一旋转方向相反 方向。 在这种配置中，通信电缆可以提供可接受的串扰和衰减性能，即使在具有相同旋转方向的双绞和聚束时已经显示出不可接受的性能的泡沫绝缘体。

公开(公告)号：US06594253B1

公开(公告)日：2003-07-15

申请号：US09163265

申请日：1998-09-29

申请人： Krister Sallberg ,  Mahesh Patel

发明人： Krister Sallberg ,  Mahesh Patel

IPC分类号： H04L1266

CPC分类号： H04W88/16 ,  H04M7/006 ,  H04M2207/18 ,  H04Q3/005 ,  H04W52/0229 ,  H04W92/02 ,  Y02D70/1222 ,  Y02D70/23

摘要： A telecommunications system and method is disclosed for providing mobility management for a Mobile Station (MS) to allow the MS to receive Internet telephone calls when the MS is in idle mode. This can be accomplished by using a voice gateway to transform an incoming Internet phone call to a normal cellular voice call. In addition, by introducing a new Intelligent Network (IN) application, which handles location updates for the MS with a central Internet telephony server, an MS in idle mode can receive incoming Internet telephony calls. The IN application can obtain a temporary Internet Protocol (IP) address for the MS from a Direct Access Unit (DAU) connected to the voice gateway associated with the serving Mobile Switching Center (MSC) and register this temporary IP address with the central Internet server, which uses this temporary IP address to forward incoming Internet telephony calls to the Voice Gateway.

摘要翻译： 公开了一种用于为移动站（MS）提供移动性管理以允许MS在MS处于空闲模式时接收因特网电话呼叫的电信系统和方法。 这可以通过使用语音网关将传入的因特网电话呼叫转换成正常的蜂窝语音呼叫来实现。 此外，通过引入一个新的智能网络（IN）应用程序，该应用程序使用中央互联网电话服务器处理MS的位置更新，处于空闲模式的MS可以接收传入的Internet电话呼叫。 IN应用可以从连接到与服务移动交换中心（MSC）相关联的语音网关的直接访问单元（DAU）获得MS的临时Internet协议（IP）地址，并将该临时IP地址与中央互联网服务器 ，其使用该临时IP地址将传入的因特网电话呼叫转发到语音网关。

公开(公告)号：US6049714A

公开(公告)日：2000-04-11

申请号：US962479

申请日：1997-10-31

申请人： Mahesh Patel

发明人： Mahesh Patel

IPC分类号： H04Q3/00 ,  H04W8/12 ,  H04W8/28 ,  H04B7/00

CPC分类号： H04W8/12 ,  H04Q3/005 ,  H04W8/28

摘要： A telecommunications system and method for routing a phone call when the switch serving the caller cannot access a database is disclosed. The system includes a switch serving mobile stations, a node for receiving information from the switch and for determining whether or not the telephone call terminates at a mobile station, a database for sending information when the telephone call terminates at a mobile station and a second database for sending information when the telephone call does not terminate at a mobile station. The method involves receiving the telephone call at a switch serving mobile stations sending information pertaining to the telephone call to a node, determining whether the telephone call terminates at a mobile station, when the telephone call does terminate at a mobile station, accessing one database, and when the call does not terminate at a mobile station, accessing a second database.

摘要翻译： 公开了当服务于呼叫者的交换机不能访问数据库时用于路由电话呼叫的电信系统和方法。 该系统包括服务移动台的交换机，用于从交换机接收信息并确定电话呼叫是否终止于移动台的节点，当电话呼叫在移动台终止时发送信息的数据库，以及第二数据库 用于在电话呼叫未终止于移动台时发送信息。 该方法包括：在服务移动站的服务器上接收电话呼叫，向移动站发送关于电话呼叫的信息，确定电话呼叫是否在移动台终止，当电话呼叫终止于移动站时，访问一个数据库， 并且当呼叫没有在移动台终止时，访问第二数据库。

公开(公告)号：US5884179A

公开(公告)日：1999-03-16

申请号：US710347

申请日：1996-09-16

申请人： Mahesh Patel

发明人： Mahesh Patel

IPC分类号： H04W8/10 ,  H04W76/02 ,  H04Q7/38

CPC分类号： H04W8/10 ,  H04W76/02

摘要： A call setup signal is routed to the gateway mobile switching center (GMSC) serving a public land mobile network (PLMN) associated with a called mobile station. The GMSC then sends a signal including data identifying the originating switch to the home location register (HLR) associated with the called mobile station. Upon determining that it would be more efficient and direct for the originating switch to release the first call connection to the GMSC and to re-originate a new call setup signal directly towards the mobile switching center (MSC) currently serving the called mobile station, the HLR transmits a Mobile Application Part (MAP) based signal to the originating switch. As a result, the originating switch releases the original call connection and re-originates a call setup signal using a roaming number identifying the MSC currently serving the mobile station as a destination address.

摘要翻译： 呼叫建立信号被路由到服务于与被叫移动台相关联的公共陆地移动网络（PLMN）的网关移动交换中心（GMSC）。 然后，GMSC将包括识别始发交换机的数据的信号发送到与被叫移动台相关联的归属位置寄存器（HLR）。 在确定对于始发交换机释放到GMSC的第一呼叫连接并直接向当前服务于被叫移动台的移动交换中心（MSC）重新发起新的呼叫建立信号将更有效和直接的情况下， HLR将基于移动应用部分（MAP）的信号发送到始发交换机。 结果，始发交换机释放原始呼叫连接，并使用标识当前服务于移动台的MSC作为目的地地址的漫游号码重新发起呼叫建立信号。

公开(公告)号：US20150165049A1

公开(公告)日：2015-06-18

申请号：US14633545

申请日：2015-02-27

申请人： Chandrashekar Giliyar ,  Srinivasan Venkateshwaran ,  Basawaraj Chickmath ,  Satish Kumar Nachaegari ,  Chidambaram Nachiappan ,  Mahesh Patel

发明人： Chandrashekar Giliyar ,  Srinivasan Venkateshwaran ,  Basawaraj Chickmath ,  Satish Kumar Nachaegari ,  Chidambaram Nachiappan ,  Mahesh Patel

IPC分类号： A61K47/44 ,  A61K9/14 ,  A61K47/14 ,  A61K47/10 ,  A61K47/20 ,  A61K47/32 ,  A61K9/20 ,  A61K47/12 ,  A61K47/22 ,  A61K31/57 ,  A61K47/26

CPC分类号： A61K31/57 ,  A61K8/63 ,  A61K9/0053 ,  A61K9/14 ,  A61K9/145 ,  A61K9/1617 ,  A61K9/1623 ,  A61K9/1635 ,  A61K9/1641 ,  A61K9/1652 ,  A61K9/1676 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2031 ,  A61K9/2054 ,  A61K9/2059 ,  A61K9/4841 ,  A61K9/4858 ,  A61K9/4866 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/20 ,  A61K47/22 ,  A61K47/26 ,  A61K47/32 ,  A61K47/44 ,  A61K2800/10 ,  A61Q11/00

摘要： The present invention provides for bioavailable oral dosage forms containing esters of 17-hydroxyprogesterone as well as related methods. The oral dosage forms can be formulated for pregnancy support and can include a therapeutically effective amount of an ester of 17-hydroxyprogesterone and a pharmaceutically acceptable carrier. In another embodiment, a pharmaceutically acceptable oral dosage form for pregnancy support is provided. The pharmaceutically acceptable oral dosage can include a therapeutically effective amount of an ester of 17-hydroxyprogesterone and a pharmaceutically acceptable carrier. The oral dosage form can, when measured using a USP Type-II dissolution apparatus in 900 mL of deionized water with 0.5 (w/v) of sodium lauryl sulfate at 50 RPM at 37° C., release at least 20 wt % of the dose of the ester of 17-hydroxyprogesterone after 60 minutes, or in the alternative release at least 20 wt % more after 60 minutes than an equivalently dosed oral dosage form without the carrier.

摘要翻译： 本发明提供含有17-羟孕酮酯的生物可利用的口服剂型以及相关方法。 口服剂型可以配制用于妊娠支持，并且可以包括治疗有效量的17-羟孕酮和药学上可接受的载体的酯。 在另一个实施方案中，提供了用于妊娠支持的药学上可接受的口服剂型。 药学上可接受的口服剂量可以包括治疗有效量的17-羟孕酮和可药用载体的酯。 口服剂型可以使用USP Type-II溶出装置在90mL的90RPM的90mL去离子水和0.5（w / v）十二烷基硫酸钠的条件下，在37℃下以50RPM释放至少20wt％ 60分钟后17-羟孕酮酯的剂量，或在替代释放中60分钟后至少20重量％比不含载体的等效给药口服剂型更多。