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公开(公告)号：US20240287018A1
公开(公告)日：2024-08-29
申请号：US18438838
申请日：2024-02-12
Applicant: Corsair Pharma, Inc.
Inventor： Cyrus K. BECKER , Meenakshi S. VENKATRAMAN , Xiaoming ZHANG , Jürg R. Pfister , Gwenaella Rescourio
IPC: C07D321/00 , A61K9/00 , A61K9/70 , A61K31/165 , A61K31/216 , A61K31/341 , A61K31/365 , A61K45/06 , C07C59/72 , C07C69/712 , C07C69/734 , C07C69/74 , C07C69/96 , C07C219/16 , C07C235/20 , C07D207/08 , C07D211/60 , C07D257/06 , C07D263/24 , C07D263/26 , C07D265/30 , C07D295/088 , C07D295/145 , C07D307/20 , C07D317/34 , C07D317/40 , C07D453/02
CPC classification number: C07D321/00 , A61K9/0014 , A61K9/7023 , A61K31/165 , A61K31/216 , A61K31/341 , A61K31/365 , A61K45/06 , C07C59/72 , C07C69/712 , C07C69/734 , C07C69/74 , C07C69/96 , C07C219/16 , C07C235/20 , C07D207/08 , C07D211/60 , C07D257/06 , C07D263/24 , C07D263/26 , C07D265/30 , C07D295/088 , C07D295/145 , C07D307/20 , C07D317/34 , C07D317/40 , C07D453/02 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2602/42 , C07C2603/14
Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
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公开(公告)号：US20240124385A1
公开(公告)日：2024-04-18
申请号：US18516407
申请日：2023-11-21
Applicant: CORSAIR PHARMA, INC.
Inventor： Xiaoming ZHANG , Meenakshi S. VENKATRAMAN , Cyrus K. BECKER
IPC: C07C69/734 , A61K9/70 , C07C53/136 , C07C59/11 , C07C59/13 , C07C69/28 , C07C69/675 , C07C69/68 , C07C69/708 , C07C69/712 , C07C69/74 , C07C69/75 , C07C69/96 , C07D305/08 , C07D307/24 , C07D307/30 , C07D309/08
CPC classification number: C07C69/734 , A61K9/7023 , C07C53/136 , C07C59/11 , C07C59/13 , C07C69/28 , C07C69/675 , C07C69/68 , C07C69/708 , C07C69/712 , C07C69/74 , C07C69/75 , C07C69/96 , C07D305/08 , C07D307/24 , C07D307/30 , C07D309/08 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2603/14
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
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公开(公告)号：US20210009501A1
公开(公告)日：2021-01-14
申请号：US16936256
申请日：2020-07-22
Applicant: CORSAIR PHARMA, INC.
Inventor： Xiaoming ZHANG , Meenakshi S. VENKATRAMAN , Cyrus K. BECKER
IPC: C07C69/734 , C07C69/732 , C07C69/013 , C07C69/26 , C07C69/675 , C07C69/708 , C07C69/712 , C07C69/96 , C07D303/48 , A61K9/00 , A61K9/70 , A61K31/216 , A61K45/06
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
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公开(公告)号：US10752605B2
公开(公告)日：2020-08-25
申请号：US16417664
申请日：2019-05-21
Applicant: CORSAIR PHARMA, INC.
Inventor： Cyrus K. Becker , Meenakshi S. Venkatraman , Xiaoming Zhang
IPC: C07D313/00 , C07C69/712 , C07D317/40 , C07D321/00 , C07D257/06 , C07D263/24 , C07D265/30 , C07D295/088 , C07D211/60 , C07D295/145 , C07D307/20 , C07C219/16 , C07C235/20 , C07D453/02 , C07C59/54 , C07C69/734 , C07C235/34 , C07D207/08 , C07D263/26 , C07D317/34 , A61K9/70 , A61K31/165 , A61K31/216 , A61K31/335 , C07C59/31
Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
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公开(公告)号：US20190290597A1
公开(公告)日：2019-09-26
申请号：US16465683
申请日：2017-12-05
Applicant: CORSAIR PHARMA, INC.
Inventor： Xiaoming ZHANG , Cyrus K. BECKER , Meenakshi S. VENKATRAMAN
Abstract: The present disclosure provides methods, compositions, devices and systems for dermal and transdermal administration of treprostinil or salts thereof, and optionally an additional therapeutic agent. Treprostinil and salts thereof can be dermally or transdermally administered to treat any medical conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
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Patent Agency Ranking
公开(公告)号：US10246403B2
公开(公告)日：2019-04-02
申请号：US15735546
申请日：2016-06-14
Applicant: CORSAIR PHARMA, INC.
Inventor： Xiaoming Zhang , Meenakshi S. Venkatraman , Cyrus K. Becker
IPC: C07C69/734 , C07C69/74 , C07C53/136 , C07C59/11 , C07C59/13 , A61K9/70 , C07D309/08 , C07C69/28 , C07C69/708 , C07C69/712 , C07D305/08 , C07C69/675 , C07C69/68 , C07C69/75 , C07C69/96 , C07D307/24
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
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公开(公告)号：US09845305B2
公开(公告)日：2017-12-19
申请号：US15296164
申请日：2016-10-18
Applicant: Corsair Pharma Inc.
Inventor： Cyrus K. Becker , Jürg R. Pfister , Gwenaella Rescourio , Meenakshi S. Venkatraman , Xiaoming Zhang
IPC: C07D321/00 , C07D307/20 , C07D317/40 , C07C235/20 , A61K31/165 , C07C69/734 , A61K31/216 , A61K31/365 , A61K31/341 , A61K45/06 , A61K9/00 , C07D317/34 , C07C69/712 , C07C219/16 , C07D453/02 , C07D257/06 , C07D263/24 , C07D263/26 , C07D265/30 , C07D207/08 , C07D295/088 , C07D211/60 , C07D295/145 , C07C59/72 , C07C69/74 , C07C69/96 , A61K9/70
CPC classification number: C07D321/00 , A61K9/0014 , A61K9/7023 , A61K31/165 , A61K31/216 , A61K31/341 , A61K31/365 , A61K45/06 , C07C59/72 , C07C69/712 , C07C69/734 , C07C69/74 , C07C69/96 , C07C219/16 , C07C235/20 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2602/42 , C07C2603/14 , C07D207/08 , C07D211/60 , C07D257/06 , C07D263/24 , C07D263/26 , C07D265/30 , C07D295/088 , C07D295/145 , C07D307/20 , C07D317/34 , C07D317/40 , C07D453/02
Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable dosage. Transdermal applications can be used.
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公开(公告)号：US09643911B2
公开(公告)日：2017-05-09
申请号：US14829180
申请日：2015-08-18
Applicant: CORSAIR PHARMA, INC.
Inventor： Xiaoming Zhang , Meenakshi S. Venkatraman , Cyrus K. Becker
IPC: C07C69/28 , C07C69/68 , C07C69/75 , C07C69/675 , C07C69/96 , C07D309/08 , C07C69/708 , C07C69/712 , C07D305/08 , C07D307/30 , A61K9/70 , C07C59/13 , C07C53/136 , C07C69/74 , C07C59/11
CPC classification number: C07C69/74 , A61K9/7023 , C07C53/136 , C07C59/11 , C07C59/13 , C07C69/28 , C07C69/675 , C07C69/68 , C07C69/708 , C07C69/712 , C07C69/75 , C07C69/96 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2603/14 , C07D305/08 , C07D307/24 , C07D307/30 , C07D309/08
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
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公开(公告)号：US11802105B2
公开(公告)日：2023-10-31
申请号：US17207975
申请日：2021-03-22
Applicant: CORSAIR PHARMA, INC.
Inventor： Xiaoming Zhang , Meenakshi S. Venkatraman , Cyrus K. Becker
IPC: C07C69/734 , C07C69/675 , C07C69/68 , C07D305/08 , C07C69/74 , C07C53/136 , C07C59/11 , C07C59/13 , A61K9/70 , C07D309/08 , C07C69/708 , C07C69/712 , C07C69/75 , C07C69/96 , C07D307/24 , C07C69/28 , C07D307/30
CPC classification number: C07C69/734 , A61K9/7023 , C07C53/136 , C07C59/11 , C07C59/13 , C07C69/28 , C07C69/675 , C07C69/68 , C07C69/708 , C07C69/712 , C07C69/74 , C07C69/75 , C07C69/96 , C07D305/08 , C07D307/24 , C07D307/30 , C07D309/08 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2603/14
Abstract: The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
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公开(公告)号：US20230331691A1
公开(公告)日：2023-10-19
申请号：US17965914
申请日：2022-10-14
Applicant: CORSAIR PHARMA, INC.
Inventor： Cyrus K. BECKER , Meenakshi S. VENKATRAMAN , Xiaoming ZHANG
IPC: C07D321/00 , C07C235/20 , A61K31/165 , C07C69/734 , A61K31/216 , A61K31/365 , C07D307/20 , A61K31/341 , A61K45/06 , A61K9/00 , C07D317/34 , C07C69/712 , C07D317/40 , C07C219/16 , C07D453/02 , C07D257/06 , C07D263/24 , C07D263/26 , C07D265/30 , C07D207/08 , C07D295/088 , C07D211/60 , C07D295/145 , C07C59/72 , C07C69/74 , C07C69/96 , A61K9/70
CPC classification number: C07D321/00 , A61K9/0014 , A61K9/7023 , A61K31/165 , A61K31/216 , A61K31/341 , A61K31/365 , A61K45/06 , C07C59/72 , C07C69/712 , C07C69/734 , C07C69/74 , C07C69/96 , C07C219/16 , C07C235/20 , C07D207/08 , C07D211/60 , C07D257/06 , C07D263/24 , C07D263/26 , C07D265/30 , C07D295/088 , C07D295/145 , C07D307/20 , C07D317/34 , C07D317/40 , C07D453/02 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2602/42 , C07C2603/14
Abstract: Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
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