公开(公告)号：US4732476A

公开(公告)日：1988-03-22

申请号：US759291

申请日：1985-07-26

Applicant: Yoav Barshad

Inventor： Yoav Barshad

IPC: G01J3/06 ,  G01J3/18 ,  G01J3/28

CPC classification number: G01J3/06 ,  G01J3/2889 ,  G01J3/1838

Abstract: An improved rapid-scan spectrophotometer with an optical grating continuously rotating at a constant angular velocity. An optical trigger actuated by the rotating turntable supporting the grating, actuates an analog to digital converter to sample at discrete times an output signal from the sample detector over the desired wavelength range and to store the digitized information in a direct memory access (DMA) buffer. The information may be retrieved as desired from the buffer for further processing or permanent data storage. With each revolution of the optical grating, the range (typically 15.degree.) of wavelengths from the grating that provides useful information is sampled by the analog to digital converter and stored in the buffer. Because the grating is continuously rotating at a constant angular velocity and is not limited by the inertia of optical components, the spectrophotometer can be operated at a much higher scanning speed than an oscillating or vibrating grating spectrophotometer.

Abstract translation: 一种改进的快速扫描分光光度计，其光栅以恒定角速度连续旋转。 由支撑光栅的旋转转盘启动的光学触发器致动模数转换器，以在离散时间对来自样品检测器的所需波长范围的输出信号进行采样，并将数字化信息存储在直接存储器存取（DMA）缓冲器 。 可以根据需要从缓冲器中检索信息以用于进一步处理或永久数据存储。 随着光栅的每次旋转，来自提供有用信息的光栅的波长范围（通常为15°）由模数转换器采样并存储在缓冲器中。 因为光栅以恒定的角速度连续旋转，并且不受光学部件的惯性的限制，所以分光光度计可以以比振荡或振动光栅分光光度计高得多的扫描速度运行。

公开(公告)号：US4632550A

公开(公告)日：1986-12-30

申请号：US657963

申请日：1984-10-05

Applicant: Kiyoaki Hara ,  Issei Yokoyama ,  Natsuki Yoshida

Inventor： Kiyoaki Hara ,  Issei Yokoyama ,  Natsuki Yoshida

IPC: G01J3/00 ,  G01J3/28 ,  G01J3/44 ,  G01J3/443

CPC classification number: G01J3/4406 ,  G01J3/2889 ,  G01N21/6408

Abstract: A measuring method for a time resolved emission spectrum or a time resolved excitation spectrum, wherein when emission transient waveforms from a pulse-excited sample are measured by the time correlation photon counting method; the emission transient waveforms are measured at every optimum wavelength in a problematical emission spectrum region; the measured emission transient waveforms are stored in a memory in order and at every wavelength; all the transient waveforms in each wavelength are measured; thereafter, the time resolved emission spectrum or the time resolved excitation spectrum is produced on the basis of all the above-mentioned stored emission transient waveform data, thereby enabling the proper spectrum to be produced efficiently.

Abstract translation: 时间分辨发射光谱或时间分辨激发光谱的测量方法，其中当通过时间相关光子计数法测量来自脉冲激发样品的发射瞬态波形时; 在有问题的发射光谱区域中的每个最佳波长处测量发射瞬态波形; 测量的发射瞬态波形按顺序和每个波长存储在存储器中; 测量每个波长中的所有瞬态波形; 此后，基于所有上述存储的发射瞬态波形数据产生时间分辨发射光谱或时间分辨激发光谱，从而能够有效地产生适当的光谱。

公开(公告)号：US4264205A

公开(公告)日：1981-04-28

申请号：US940360

申请日：1978-09-07

Applicant: Isaac J. Landa

Inventor： Isaac J. Landa

IPC: G01J3/02 ,  G01J3/06 ,  G01J3/10 ,  G01J3/12 ,  G01J3/18 ,  G01J3/26 ,  G01J3/28 ,  G01N21/31

CPC classification number: G01J3/06 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0221 ,  G01J3/0232 ,  G01J3/024 ,  G01J3/0262 ,  G01J3/10 ,  G01J3/26 ,  G01J3/2889 ,  G01N21/314 ,  G01J2003/1273 ,  G01J2003/2853 ,  G01J3/1838

Abstract: An improved optical system is disclosed for rapid, accurate spectral analysis of the reflectivity or transmissivity of samples. A concave holographic diffraction grating oscillated at high speed is utilized to provide a rapid scanning of monochromatic light through a spectrum of wavelengths. The grating is positively driven at very high speed. The rapid scan by the grating enables the reduction of noise error by averaging over a large number of cycles. It also reduces the measurement time and thus prevents sample heating by excessive exposure to light energy. A filter wheel having opaque segments is rotated in the optical path and is synchronous with the grating. The filter wheel is divided into two arcuate segments separated by the opaque segments arranged approximately 180 degrees apart. One arcuate segment of the wheel transmits only first order light. The other arcuate segment transmits only second order light. Separate photodetectors are employed during infrared analysis of samples for detecting first order and second order wavelength transmissions and an electronic decoder apparatus is utilized for switching between detectors.

Abstract translation: 公开了一种改进的光学系统，用于对样品的反射率或透射率进行快速，准确的光谱分析。 利用以高速振荡的凹面全息衍射光栅，通过一系列波长快速扫描单色光。 光栅以非常高的速度被正向驱动。 光栅的快速扫描使得能够通过大量循环的平均来减少噪声误差。 它还减少测量时间，从而防止过度暴露于光能的样品加热。 具有不透明段的滤光轮在光路中旋转并与光栅同步。 过滤轮被分成两个弧形段，这些弧段由分开大约180度的不透明段分开。 车轮的一个弧形段仅传送一级光。 另一个弧形段仅传送二阶光。 在用于检测一阶和二阶波长传输的样本的红外分析期间采用单独的光电检测器，并且使用电子解码器装置在检测器之间切换。

公开(公告)号：US3765769A

公开(公告)日：1973-10-16

申请号：US3765769D

申请日：1972-04-26

Applicant: UNITED AIRCRAFT CORP

Inventor： TREACY E

IPC: G01J3/28 ,  G01J3/40 ,  G01J3/12 ,  G01J3/42

CPC classification number: G01J3/2889

Abstract: A device for producing a dynamic spectrogram of a picosecond pulse of electromagnetic radiation is described. A technique for recording the component wavelengths and their relative intensity as a function of time for the pulse is also discussed.

Abstract translation: 描述了用于产生电磁辐射皮秒脉冲的动态光谱图的装置。 还讨论了用于记录脉冲的分量波长及其相对强度作为时间的函数的技术。

公开(公告)号：US3392624A

公开(公告)日：1968-07-16

申请号：US40965964

申请日：1964-11-09

Applicant: KETTERING FOUND CHARLES F

Inventor： BACON KE ,  TREHARNE RICHARD W ,  MCKIBBEN CHARLTON K

IPC: G01J3/28 ,  G01N21/63

CPC classification number: G01J3/2889 ,  G01N21/631

公开(公告)号：US3315560A

公开(公告)日：1967-04-25

申请号：US16830362

申请日：1962-01-10

Applicant: ARPAD BARDOCZ

Inventor： ARPAD BARDOCZ

IPC: G01J3/28

CPC classification number: G01J3/2889

公开(公告)号：US12025557B2

公开(公告)日：2024-07-02

申请号：US17578932

申请日：2022-01-19

Applicant: Black Light Surgical, Inc. ,  Cedars-Sinai Medical Center

Inventor： Pramod Butte ,  Keith Black ,  Jack Kavanaugh ,  Bartosz Bortnik ,  Zhaojun Nie

IPC: G01N21/64 ,  G01J3/02 ,  G01J3/10 ,  G01J3/28 ,  G01J3/32 ,  G01J3/44 ,  G01J3/12

CPC classification number: G01N21/6408 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/2889 ,  G01J3/32 ,  G01J3/4406 ,  G01N21/6402 ,  G01J2003/1213 ,  G01J2003/1265 ,  G01N2021/6484

Abstract: Provided herein are devices, systems, and methods for characterizing a biological sample in vivo or ex vivo in real-time using time-resolved spectroscopy. A light source generates a light pulse or continuous light wave and excites the biological sample, inducing a responsive fluorescent signal. A demultiplexer splits the signal into spectral bands and a time delay is applied to the spectral bands so as to capture data with a detector from multiple spectral bands from a single excitation pulse. The biological sample is characterized by analyzing the fluorescence intensity magnitude and/or decay of the spectral bands. The sample may comprise one or more exogenous or endogenous fluorophore. The device may be a two-piece probe with a detachable, disposable distal end. The systems may combine fluorescence spectroscopy with other optical spectroscopy or imaging modalities. The light pulse may be focused at a single focal point or scanned or patterned across an area.

公开(公告)号：US20180375478A1

公开(公告)日：2018-12-27

申请号：US15628965

申请日：2017-06-21

Applicant: Board of Regents, The University of Texas System

Inventor： Navneet Sharma ,  Kenneth K. O

IPC: H03F1/22 ,  H04B1/18 ,  H03L7/197 ,  H03D7/16 ,  H03H11/22 ,  H04B1/28 ,  H03D7/14 ,  G01J3/28 ,  G01J3/06

CPC classification number: H03F1/223 ,  G01J3/06 ,  G01J3/2889 ,  H03D7/1441 ,  H03D7/1458 ,  H03D7/1466 ,  H03D7/165 ,  H03F3/193 ,  H03F3/265 ,  H03F2200/405 ,  H03F2200/451 ,  H03F2200/534 ,  H03F2200/537 ,  H03F2200/541 ,  H03H11/22 ,  H03L7/1974 ,  H04B1/0475 ,  H04B1/18 ,  H04B1/28

Abstract: A radio frequency (RF) front-end for a transmitter in a complementary metal-oxide-semiconductor (CMOS) includes a mixer based core that itself includes first and second input signals; an amplifier that amplifies the first signal and transmits a corresponding amplified first signal; an up-conversion mixer that receives the amplified first signal and the second signal through transistors, and mixes the amplified first signal and second signal and generates a radio frequency (RF) signal; and an antenna that receives the RF signal and transmits the signal from the front-end.

公开(公告)号：US20180130651A1

公开(公告)日：2018-05-10

申请号：US15727198

申请日：2017-10-06

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： VLADIMIR VOLYNETS ,  Protopopov Vladimir ,  Young Do Kim ,  Yuri Barsukov ,  Sang Heon Lee ,  Sung Ho Jang

IPC: H01J49/40 ,  G01J3/443 ,  H01J49/10 ,  H01J49/00 ,  H01J49/12 ,  H01L21/02 ,  C23C16/455 ,  H01J37/32 ,  H01L29/786

CPC classification number: H01J49/40 ,  C23C16/45502 ,  G01J3/2889 ,  G01J3/443 ,  H01J37/32963 ,  H01J49/0031 ,  H01J49/10 ,  H01J49/12 ,  H01J2237/327 ,  H01L21/02274 ,  H01L29/78696

Abstract: A pulsed plasma analyzer includes a pulse modulator that controls an off-time of a pulsed plasma that includes a target radical, an optical spectrometer that measures optical emissions of the pulsed plasma after the off-time to determine optical emission data, and a concentration estimating module that estimates a concentration of the target radical during the off-time based on an initial optical emission value of the optical emission data that changes as a function of the off-time, and outputs an estimated concentration.

公开(公告)号：US20170284940A1

公开(公告)日：2017-10-05

申请号：US15475750

申请日：2017-03-31

Applicant: Black Light Surgical, Inc. ,  Cedars-Sinai Medical Center

Inventor： Pramod BUTTE ,  Keith BLACK ,  Jack KAVANAUGH

IPC: G01N21/64 ,  G01J3/02 ,  G01J3/44

CPC classification number: G01N21/6408 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/2889 ,  G01J3/32 ,  G01J3/4406 ,  G01J2003/1213 ,  G01J2003/1265 ,  G01N21/6402 ,  G01N2021/6484

Abstract: Provided herein are devices, systems, and methods for characterizing a biological sample in vivo or ex vivo in real-time using time-resolved spectroscopy. A light source generates a light pulse or continuous light wave and excites the biological sample, inducing a responsive fluorescent signal. A demultiplexer splits the signal into spectral bands and a time delay is applied to the spectral bands so as to capture data with a detector from multiple spectral bands from a single excitation pulse. The biological sample is characterized by analyzing the fluorescence intensity magnitude and/or decay of the spectral bands. The sample may comprise one or more exogenous or endogenous fluorophore. The device may be a two-piece probe with a detachable, disposable distal end. The systems may combine fluorescence spectroscopy with other optical spectroscopy or imaging modalities. The light pulse may be focused at a single focal point or scanned or patterned across an area.