Systems and methods for optical actuation of microfluidics based on OPTO-electrowetting
    72.
    发明申请
    Systems and methods for optical actuation of microfluidics based on OPTO-electrowetting 有权
    基于OPTO电润湿的微流体光学致动系统和方法

    公开(公告)号:US20070243110A1

    公开(公告)日:2007-10-18

    申请号:US11209587

    申请日:2005-08-22

    申请人: Pei Chiou Ming Wu

    发明人: Pei Chiou Ming Wu

    IPC分类号: B01L3/02

    摘要: The invention is related to methods and apparatus that manipulate droplets in a microfluidic environment. Advantageously, embodiments of the invention manipulate droplets by controlling the electro-wetting characteristics of a surface with light, thereby inducing a gradient in the surface tension of a droplet. The gradient in the surface tension propels the droplet by capillary force. A variety of operations, such as transporting, joining, cutting, and creating can be performed. Advantageously, embodiments of the invention obviate the need to create a relatively large and complex control electrode array. A plurality of photoconductive cells or a layer of a photoconductive material selectively couples an electrode carrying an electrical bias to otherwise floating conductive cells in response to a beam of light. The electrical bias applied to the conductive cell generates a localized electric field, which can change the contact angle of the droplet, thereby permitting the droplet to be propelled.

    摘要翻译: 本发明涉及在微流体环境中操纵液滴的方法和装置。 有利地,本发明的实施例通过用光控制表面的电润湿特性来操纵液滴,由此引起液滴的表面张力的梯度。 表面张力的梯度通过毛细管力推动液滴。 可以进行各种操作,例如运输,连接,切割和创建。 有利地,本发明的实施例消除了产生相对较大和复杂的控制电极阵列的需要。 响应于光束,多个光电导电池或光电导材料层将携带电偏压的电极选择性地耦合到另外的浮动导电单元。 施加到导电电池的电偏压产生局部电场,这可以改变液滴的接触角,从而允许液滴被推进。

    Multiple port dual diameter pumps
    74.
    发明授权
    Multiple port dual diameter pumps 失效
    多端口双直径泵

    公开(公告)号:US07207780B2

    公开(公告)日:2007-04-24

    申请号:US10965287

    申请日:2004-10-14

    申请人: David T. Bach

    发明人: David T. Bach

    IPC分类号: F04B43/12

    摘要: A multiple port, dual diameter piston fluid dispensing pump which includes multiple input and output ports accessed by rotating at least one of the pistons and a dual or multiple diameter piston or set of pistons that cooperate so that they follow each other. The dispensing piston is of smaller diameter than the pushing piston. This diameter difference permits a longer, controllable stroke to dispense micro-liters of fluid accurately.

    摘要翻译: 多端口双直径活塞流体分配泵,其包括通过旋转至少一个活塞和双或多个直径的活塞或一组活塞相互接触的多个输入和输出端口。 分配活塞的直径小于推动活塞的直径。 该直径差允许更长的可控行程精确地分配微升的流体。

    Automated micro-volume assay system
    79.
    发明申请
    Automated micro-volume assay system 有权
    自动微量测定系统

    公开(公告)号:US20060249558A1

    公开(公告)日:2006-11-09

    申请号:US11401699

    申请日:2006-04-10

    IPC分类号: A47J36/02

    摘要: An automated assay system is described with stations for placement of materials to be used in an assay of materials inside capillaries and an automated gripper for manipulating capillaries. The system includes a separation and immobilization station where reactions inside the capillaries take place and a detector station where photoemissions from the capillary reactions are detected. The photoemissions from the capillaries may be displayed as line graphs or in columns of a pseudo-gel image resembling the familiar Western gel blot. An automated control system has a user interface by which an operator can select a run protocol and define the locations of samples and reagents to be used in the protocol run. Following the setup the control system will cause the automated system to execute the protocol, then display the results in a selected display format.

    摘要翻译: 描述了用于放置用于毛细管内部的材料测定的材料的站的自动测定系统和用于操纵毛细管的自动化夹具。 该系统包括分离和固定站,其中毛细管内部发生反应,并且检测到来自毛细血管反应的光摄取的检测器站。 来自毛细血管的光摄取可以显示为线图或类似于熟悉的Western凝胶印迹的假凝胶图像的列。 自动化控制系统具有用户界面,通过该界面,操作员可以选择运行协议并定义要在协议运行中使用的样本和试剂的位置。 在设置之后,控制系统将使自动化系统执行协议,然后以选定的显示格式显示结果。