Patent search ipc:"C07C63/74" Page 6

51.

发明授权
Halo-substituted-5H-dibenzo{8 a,d{9 cyclohepten-5-ones 失效
Title translation: 卤代取代-5H-二苯并{8a，d {9环庚烯-5-酮

公开(公告)号：US3919321A

公开(公告)日：1975-11-11

申请号：US44942674

申请日：1974-03-08

Applicant: HOFFMANN LA ROCHE

Inventor： KYBURZ EMILIO , SPIEGELBERG HANS

IPC: C07C63/72 , C07C63/74 , C07C49/80

CPC classification number: C07C63/74 , C07C63/72

Abstract: 1-Chloro- or 1-fluoro- derivatives of 5H-dibenzo(a, d)cycloheptenes and 1-chloro- or 1-fluoro- derivatives of 10,11dihydro-5H-dibenzo(a,d)cycloheptenes having, at position 5, a basic exocyclic side chain of the formula

wherein R1 is hydrogen or methyl, and intermediates therefor are prepared by alternate procedures. The described end-products are useful, for example, as psychopharmacological antidepressants.

Abstract translation: 1,5-二苯并[a，d]环庚烯的1-氯 - 或1-氟 - 衍生物和10,11-二氢-5H-二苯并[a，d]环庚烯的1-氯 - 或1-氟 - 衍生物，其具有位置5，式R 1 -CH 2 -CH 2 -CH 2 -N-ANGLE XIII CH 3或R 1 = CH-CH 2 -CH 2 -N-ANGLE XIV CH 3的基本环外侧链，其中R 1是氢或甲基，以及其中间体是通过交替程序。所描述的最终产品是有用的，例如作为精神药物抗抑郁药。

52.

发明授权
7-substituted pleiadenes and 8-substituted dibenzoheptalenes 失效
Title translation: 7-取代的PLEIADENES和8-取代的二苯并噻吩

公开(公告)号：US3795676A

公开(公告)日：1974-03-05

申请号：US3795676D

申请日：1972-11-14

Applicant: SANDOZ AG

Inventor： HOULIHAN W , NADELSON J

IPC: C07C63/49 , C07C63/66 , C07C63/72 , C07C63/74 , C07C65/17 , C07C65/19 , C07C65/26 , C07D211/08 , C07D211/14 , C07D211/18 , C07D211/22 , C07D311/96 , C07D29/12

CPC classification number: C07C65/26 , C07C63/49 , C07C63/66 , C07C63/72 , C07C63/74 , C07C65/17 , C07C65/19 , C07D211/08 , C07D211/14 , C07D211/18 , C07D211/22 , C07D311/96

Abstract: PLEIADENES SUBSTITUTED AT THE 7-POSITION, E.G. 1,2,3,7TETRAHYDRO-7-(1-METHYL-4-PIPERIDYL)PLEIADENE AND 1,2,3, 7,12,12A-HEXAHYDRO-7-(1 - METHYL-4-PIPERIDYL)PLEIADEN-7OL, AND DIBENZOHEPTALENES SUBSTITUTED AT THE 8-POSITION, E.G. 1,2,3,4-TETRAHYDRO-8 - (1-METHYL-4-PIPERIDYL)-8H-DIBENZO(B,EF)HEPTALENE, PREPARED FROM A CORRESPONDING KETONE AND GRIGNARD REAGENT, ARE USEFUL AS CENTRAL NERVOUS SYSTEM STIMULTANTS.

53.

发明授权
Vinyl aromatic aminimides and polymers thereof 失效
Title translation: VINYL AROMATIC AMINIMIDES及其聚合物

公开(公告)号：US3756994A

公开(公告)日：1973-09-04

申请号：US3756994D

申请日：1971-09-13

Applicant: ASHLAND OIL INC

Inventor： CULBERTSON B , MC KILLIP W , SEDOR E

IPC: C07C63/74 , C08F2/00 , C08F12/14 , C08F20/52 , C08F26/00 , C08G18/72 , C08L75/04 , C08F15/00 , C08G22/18

CPC classification number: C08F20/52 , C07C63/74 , C07C243/00 , C08F2/00 , C08F26/00 , Y10S526/923

Abstract: WHEREIN R IS A HYDROGEN, METHYL, OR HALOGEN; N IS ZERO OR ONE AND R1, R2, AND R3 ARE HYDROCARBON RADICALS AND R1 AND R2 CAN BE COMBINED TO FORM A HETEROCYLIC RING WITH THE NITROGEN.

CH2=C(-R)-C6H4-(CH2)N-CO-N(-)-N(+)(-R1)(-R2)-R3

VINYL AROMATIC AMINIMIDES ARE PREPARED FROM VINYL AROMATIC ACIDS OR DERIVATIVES THEREOF. THE VINYL AROMATIC AMINIMIDE CAN BE HOMOPOLYMERIZED AND COPOLYMERIZED TO RESULT IN FUNCTIONAL GROUP-CONTAINING POLYMERIC PRODUCTS CAPABLE OF THERMOSETTING. THE VINYL AROMATIC AMINIMIDES HAVE THE GENERAL FORMULA

54.

发明授权
1,2,3 12a-titrahydro-7(2h)plaidomenones 失效
Title translation: 1,2,3 12A-TITRAHYDRO-7（2H）PLAIDONONES

公开(公告)号：US3719280A

公开(公告)日：1973-03-06

申请号：US3719280D

申请日：1970-10-01

Applicant: SANDOZ AG

Inventor： HOULIHAN W , NADELSON J

IPC: C07C63/49 , C07C63/66 , C07C63/72 , C07C63/74 , C07C65/17 , C07C65/19 , C07C65/26 , C07D211/08 , C07D211/14 , C07D211/18 , C07D211/22 , C07D311/96 , C07C49/76 , C07C49/80 , C07C49/82

CPC classification number: C07C63/49 , C07C63/66 , C07C63/72 , C07C63/74 , C07C65/17 , C07C65/19 , C07C65/26 , C07D211/08 , C07D211/14 , C07D211/18 , C07D211/22 , C07D311/96

Abstract: Pleiadenes substituted at the 7-position, e.g. 1,2,3,7tetrahydro-7(1-methyl-4-piperidyl)pleiadene and 1,2,3,7,12,12a hexahydro-7-(1-methyl-4-piperidyl)pleiaden-7-ol, and dibenzoheptalenes substituted at the 8-position, e.g. 1,2,3,4tetrahydro-8-(1-methyl-4-piperidyl)-8H-dibenzo(b,ef)heptalene, prepared from a corresponding ketone and Grignard reagent, are useful as anti-convulsants.

Abstract translation: 在7-位上取代的Pleiadenes，例如 1,2,3,4-四氢-7（1-甲基-4-哌啶基）倍半萜烯和1,2,3,7,12,12a六氢-7-（1-甲基-4-哌啶基）倍半碳-7-酮和在8-位取代的二苯并庚醛，例如由相应的酮和格氏试剂制备的1,2,3,4-四氢-8-（1-甲基-4-哌啶基）-8H-二苯并[b，ef]七氢萘可用作抗惊厥药。

55.

发明授权
Indenyl acids and derivatives thereof 失效
Title translation: 茚基酸及其衍生物

公开(公告)号：US3312730A

公开(公告)日：1967-04-04

申请号：US49818165

申请日：1965-09-14

Applicant: WINTER CHARLES A , TSUNG-YING SHEN

Inventor： WINTER CHARLES A , TSUNG-YING SHEN

IPC: A61K31/19 , C07C45/46 , C07C45/71 , C07C49/697 , C07C49/755 , C07C51/09 , C07C51/36 , C07C57/48 , C07C57/50 , C07C57/58 , C07C57/60 , C07C57/62 , C07C59/56 , C07C59/72 , C07C59/90 , C07C63/34 , C07C63/74 , C07C205/56 , C07C233/12 , C07D257/04 , C07D295/145 , C07D295/185 , C07D333/42

CPC classification number: C07D295/185 , C07C45/46 , C07C45/71 , C07C49/697 , C07C49/755 , C07C51/09 , C07C51/36 , C07C57/48 , C07C57/58 , C07C57/60 , C07C57/62 , C07C59/56 , C07C59/72 , C07C59/90 , C07C63/34 , C07C63/74 , C07C205/56 , C07C309/00 , C07C321/00 , C07C323/00 , C07C2602/08 , C07D295/145 , C07D333/42 , Y10S514/825 , Y10S514/916

56.

发明授权
Oxy-cope rearrangement for the manufacture of insecticidal cyclopentene compounds 有权

公开(公告)号：US10526264B2

公开(公告)日：2020-01-07

申请号：US16315417

申请日：2017-06-23

Applicant: BASF SE

Inventor： Martin John McLaughlin , Karsten Koerber , Birgit Gockel , Pascal Bindschaedler , Sebastian Soergel , Devendra Vyas , Johannes Roeckl

IPC: C07C33/00 , C07C17/00 , C07C25/00 , C07C45/00 , C07C63/00 , C07C33/48 , C07C49/813 , C07C45/51 , C07C63/74 , C07C17/263 , C07C25/24

Abstract: Compounds of formula I a process for preparation of compounds of formula I; precursor compounds of formula II a process for preparation of precursor compounds of formula II; compounds of formula III a process for the preparation of compounds of formula IV from compounds of formula III and the use of compounds of formula I for the preparation of compounds of formula IV.

57.

发明申请
OXY-COPE REARRANGEMENT FOR THE MANUFACTURE OF INSECTICIDAL CYCLOPENTENE COMPOUNDS 审中-公开

公开(公告)号：US20190308920A1

公开(公告)日：2019-10-10

申请号：US16315417

申请日：2017-06-23

Applicant: BASF SE

Inventor： Martin John MCLAUGHLIN , Karsten KOERBER , Birgit GOCKEL , Pascal BINDSCHAEDLER , Sebastian SOERGEL , Devendra VYAS , Johannes ROECKL

IPC: C07C33/48 , C07C49/813 , C07C25/24 , C07C63/74 , C07C17/263 , C07C45/51

Abstract: Compounds of formula I a process for preparation of compounds of formula I; precursor compounds of formula II a process for preparation of precursor compounds of formula II; compounds of formula III a process for the preparation of compounds of formula IV from compounds of formula III and the use of compounds of formula I for the preparation of compounds of formula IV.

58.

发明授权
Compositions and methods for modification of biomolecules 有权

公开(公告)号：US10434111B2

公开(公告)日：2019-10-08

申请号：US15043181

申请日：2016-02-12

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Carolyn Ruth Bertozzi , Nicholas J. Agard , Jennifer A. Prescher , Jeremy Michael Baskin , Ellen May Sletten

IPC: A61K31/655 , C07C45/29 , C07C45/51 , C07C45/63 , C07C49/497 , C07C49/753 , C07C59/72 , C07C63/66 , C07C63/74 , C07C69/708 , C07C69/76 , C07C57/26 , C07D207/416 , C07D207/452 , C07D249/16 , C07D495/04 , C07C49/457 , G01N33/531 , G01N33/68

Abstract: The present invention provides modified cycloalkyne compounds; and method of use of such compounds in modifying biomolecules. The present invention features a cycloaddition reaction that can be carried out under physiological conditions. In general, the invention involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provide for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).