公开(公告)号：US20240140917A1

公开(公告)日：2024-05-02

申请号：US18276304

申请日：2022-01-31

Applicant: BASF SE

Inventor： Nikolas Huwyler ,  Karsten Koerber ,  Erik Gilberg ,  Sunderraman Sambasivan

IPC: C07D261/14 ,  A01P7/04 ,  C07D413/12

CPC classification number: C07D261/14 ,  A01P7/04 ,  C07D413/12

Abstract: The invention relates to isoxazoline compounds of formula (I) wherein the variables have the meanings as defined in the specification, to compositions comprising them, to active compound combinations comprising them, and to their use for protecting growing plants and animals from attack or infestation by invertebrate pests, furthermore, to seed comprising such compounds.

公开(公告)号：US11440861B2

公开(公告)日：2022-09-13

申请号：US17295102

申请日：2019-11-25

Applicant: BASF SE

Inventor： Karsten Koerber ,  Michael Rack ,  Pascal Bindschaedler ,  Martin John McLaughlin ,  Birgit Gockel ,  Devendra Vyas ,  Sebastian Soergel

IPC: C07C17/35 ,  B01J21/18 ,  B01J23/44 ,  C07C25/08 ,  C07C245/20 ,  C07C37/045 ,  C07C39/30 ,  C07C17/093

Abstract: The invention relates to a process for the preparation of 5-bromo-1,3-dichloro-2-fluoro-benzene by diazotization and reduction of 6-bromo-2,4-dichloro-3-fluoro-aniline, which is obtained by bromination of 2,4-dichloro-3-fluoro-aniline, which is obtained by reduction of 1,3-dichloro-2-fluoro-4-nitro-benzene, and a process for preparing active compounds of formula V (Formula V) wherein the variables are defined in the specification by further transforming 5-bromo-1,3-dichloro-2-fluoro-benzene obtained from 2,4-dichloro-3-fluoro-aniline by the process according to the invention.

公开(公告)号：US20220002284A1

公开(公告)日：2022-01-06

申请号：US17291402

申请日：2019-11-18

Applicant: BASF SE

Inventor： Arun Narine ,  Rupsha Chaudhuri ,  Pulakesh Maity ,  Sunderraman Sambasivan ,  Wolfgang von Deyn ,  Joachim Dickhaut ,  Nikolas Huwyler ,  Karsten Koerber ,  Olesya Kuzmina

IPC: C07D417/12 ,  A01N25/30 ,  A01N43/78

Abstract: The present invention relates to the compounds of formula (I), and the N-oxides, stereoisomers, tautomers and agriculturally or veterinarily acceptable salts thereof wherein the variables are defined according to description formula (I). The compounds of formula (I), as well as the N-oxides, stereoisomers, tautomers and agriculturally or veterinarily acceptable salts thereof, are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.

公开(公告)号：US20210340113A1

公开(公告)日：2021-11-04

申请号：US17284199

申请日：2019-10-18

Applicant: BASF SE

Inventor： Karsten Koerber ,  Nikolas Huwyler ,  Arun Narine ,  Martin John McLaughlin ,  Kailaskumar Borate

IPC: C07D261/04 ,  C07D491/107

Abstract: The present invention relates to a process for preparing benzylic amides of formula (I) wherein the variables are as defined in the specification, and the shown enantiomer has at least 50% ee; by condensation of a ketone o formula (II) with an acetyl compound of formula (III) in the presence of a catalyst of formula (IV) wherein the variables are as defined in the specification.

公开(公告)号：US09282741B2

公开(公告)日：2016-03-15

申请号：US14684508

申请日：2015-04-13

Applicant: BASF SE

Inventor： Karsten Koerber ,  Prashant Deshmukh ,  Florian Kaiser ,  Michael Rack ,  Timo Frasetto ,  Gemma Zünd ,  Markus Kordes ,  Marco Naujok

IPC: C07C313/00 ,  A01N41/12 ,  A01N43/56 ,  A01N43/80 ,  C07D401/04 ,  C07C381/10 ,  C07D401/14 ,  C07D413/14 ,  C07D409/14 ,  A01N37/28 ,  A01N43/50

CPC classification number: A01N43/56 ,  A01N37/28 ,  A01N41/12 ,  A01N43/50 ,  A01N43/80 ,  C07B2200/13 ,  C07C381/10 ,  C07D401/04 ,  C07D401/14 ,  C07D409/14 ,  C07D413/14

Abstract: The present invention relates to a crystalline form of 2-(3-chloro-2-pyridyl)-N-[2-methyl-4-chloro-6-[(diethyl-λ4-sulfanylidene)carbamoyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide. The present invention also relates to a method for controlling invertebrate pest, which method comprises contacting the invertebrate pest or their food supply, habitat, breeding grounds or their locus with a pesticidally effective amount of a crystalline form of 2-(3-chloro- 2-pyridyl)-N-[2-methyl-4-chloro-6-[(diethyl-λ4-sulfanylidene)carbamoyl]phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide.

Abstract translation: 本发明涉及2-（3-氯-2-吡啶基）-N- [2-甲基-4-氯-6 - [（二乙基-λ4亚硫基）氨基甲酰基]苯基] -5-（ 三氟甲基）吡唑-3-甲酰胺。 本发明还涉及一种控制无脊椎害虫的方法，该方法包括使无脊椎害虫或其食物供应，栖息地，繁殖地或其基因座与农药有效量的2-（3-氯-2- - 吡啶基）-N- [2-甲基-4-氯-6 - [（二乙基-λ4亚硫基）氨基甲酰基]苯基] -5-（三氟甲基）吡唑-3-甲酰胺。

公开(公告)号：US09204647B2

公开(公告)日：2015-12-08

申请号：US14073369

申请日：2013-11-06

Applicant: BASF SE

Inventor： Steffen Gross ,  Delphine Breuninger ,  Henricus Maria Martinus Bastiaans ,  Wolfgang von Deyn ,  Michael Puhl ,  Karsten Koerber ,  Douglas D. Anspaugh ,  Deborah L. Culberston ,  Hassan Oloumi-Sadeghi

IPC: A01N43/40 ,  A61K31/4439 ,  A01N43/707 ,  C07D401/12 ,  C07D401/14 ,  A01P7/00 ,  A01N43/64 ,  A01N43/56 ,  A01N43/74 ,  A01N47/18 ,  C07D417/14

CPC classification number: A01N43/64 ,  A01N43/56 ,  A01N43/707 ,  A01N43/74 ,  A01N47/18 ,  C07D401/12 ,  C07D401/14 ,  C07D417/14

Abstract: The present invention relates to novel pyrazole compounds of the formulae I and II, to their salts and their N-oxides which can be used for combating or controlling invertebrate pests, in particular arthropod pests. The invention also relates to a method for controlling invertebrate pests by using these compounds. The present invention also relates to seed and to an agricultural and veterinary composition comprising said compounds. wherein A is a pyrazole radical of the formulae A1, A2 or A3 # denotes the binding site to the remainder of formulae I or II; X1 is S, O or NR1a; X2 is OR2a, NR2bR2c, S(O)mR2d; X3 is a lone pair or oxygen; R1, R2 and R3 are, inter alia, hydrogen, and wherein R41, R42, R43, R51, R52, R53, R61, R62, R63, are as defined in claim 1.

Abstract translation: 本发明涉及式I和II的新型吡唑化合物及其盐及其N-氧化物，其可用于防治或控制无脊椎动物害虫，特别是节肢动物害虫。 本发明还涉及通过使用这些化合物来控制无脊椎害虫的方法。 本发明还涉及种子和包含所述化合物的农业和兽医组合物。 其中A是式A1，A2或A3的吡唑基，A3表示与式I或II的其余部分的结合位点; X1是S，O或NR1a; X2是OR2a，NR2bR2c，S（O）mR2d; X3是孤对或氧气; R1，R2和R3尤其是氢，并且其中R41，R42，R43，R51，R52，R53，R61，R62，R63如权利要求1中所定义。

公开(公告)号：US20210000118A1

公开(公告)日：2021-01-07

申请号：US15999594

申请日：2017-02-09

Applicant: BASF SE

Inventor： Robert Reinhard ,  Pascal Bindschaedler ,  Karsten Koerber ,  Juergen Langewald

IPC: A01N43/90 ,  A01N43/713 ,  A01N43/56 ,  A01N43/80

Abstract: Pesticidal mixtures including a pesticidally active anthranilamide compound of formula (I) and at least one further pesticidal active ingredient. The pesticidal mixtures are useful for combating and controlling insects, acarids or nematodes in and on plants, and for protecting such plants being infested with pests.

公开(公告)号：US10526264B2

公开(公告)日：2020-01-07

申请号：US16315417

申请日：2017-06-23

Applicant: BASF SE

Inventor： Martin John McLaughlin ,  Karsten Koerber ,  Birgit Gockel ,  Pascal Bindschaedler ,  Sebastian Soergel ,  Devendra Vyas ,  Johannes Roeckl

IPC: C07C33/00 ,  C07C17/00 ,  C07C25/00 ,  C07C45/00 ,  C07C63/00 ,  C07C33/48 ,  C07C49/813 ,  C07C45/51 ,  C07C63/74 ,  C07C17/263 ,  C07C25/24

Abstract: Compounds of formula I a process for preparation of compounds of formula I; precursor compounds of formula II a process for preparation of precursor compounds of formula II; compounds of formula III a process for the preparation of compounds of formula IV from compounds of formula III and the use of compounds of formula I for the preparation of compounds of formula IV.

公开(公告)号：US09556141B2

公开(公告)日：2017-01-31

申请号：US14359446

申请日：2012-11-20

Applicant: BASF SE

Inventor： Maximilian Dochnahl ,  Karsten Koerber ,  Prashant Deshmukh ,  Florian Kaiser ,  Michael Rack ,  Timo Frassetto ,  Gemma Veitch

IPC: C07D401/14 ,  C07D471/10 ,  C07D401/04

CPC classification number: C07D401/04 ,  C07D471/10

Abstract: The present invention relates to a process for preparing an N-substituted 1H-pyrazole-5-carboxylate compound of the formula (I-A) comprising the steps of i) deprotonating a compound of the formula (II) in which the variables R1, R2 and r are each as defined in the description and the claims, with a magnesium-organic base having a carbon bound magnesium; and ii) subjecting the product obtained in step (i) to a carbonylation by reacting it with a reagent selected from the group consisting carbon dioxide or a carbon dioxide equivalent, to obtain a compound of formula (I-A); and it relates to further conversions to yield a N-substituted 1H-pyrazole-5-carbonyl chloride compound of the formula (I)

Abstract translation: 本发明涉及制备式（IA）的N-取代的1H-吡唑-5-羧酸酯化合物的方法，包括以下步骤：i）将式（II）的化合物去质子化，其中变量R1，R2和 r各自如说明书和权利要求中所定义，其中镁 - 有机碱具有碳结合的镁; 和ii）通过使步骤（i）中获得的产物与选自二氧化碳或二氧化碳当量的试剂反应来进行羰基化，得到式（I-A）化合物; 并且涉及进一步转化得到式（I）的N-取代的1H-吡唑-5-碳酰氯化合物，

公开(公告)号：US20150087843A1

公开(公告)日：2015-03-26

申请号：US14359446

申请日：2012-11-20

Applicant: BASF SE

Inventor： Maximilian Dochnahl ,  Karsten Koerber ,  Prashant Deshmukh ,  Florian Kaiser ,  Michael Rack ,  Timo Frassetto ,  Gemma Veitch

IPC: C07D401/04

CPC classification number: C07D401/04 ,  C07D471/10

Abstract: The present invention relates to a process for preparing an N-substituted 1H-pyrazole-5-carboxylate compound of the formula (I-A) comprising the steps of i) deprotonating a compound of the formula (II) in which the variables R1, R2 and r are each as defined in the description and the claims, with a magnesium-organic base having a carbon bound magnesium; and ii) subjecting the product obtained in step (i) to a carbonylation by reacting it with a reagent selected from the group consisting carbon dioxide or a carbon dioxide equivalent, to obtain a compound of formula (I-A); and it relates to further conversions to yield a N-substituted 1H-pyrazole-5-carbonyl chloride compound of the formula (I)

Abstract translation: 本发明涉及制备式（IA）的N-取代的1H-吡唑-5-羧酸酯化合物的方法，包括以下步骤：i）将式（II）的化合物去质子化，其中变量R1，R2和 r各自如说明书和权利要求中所定义，其中镁 - 有机碱具有碳结合的镁; 和ii）通过使步骤（i）中获得的产物与选自二氧化碳或二氧化碳当量的试剂反应来进行羰基化，得到式（I-A）化合物; 并且涉及进一步转化得到式（I）的N-取代的1H-吡唑-5-碳酰氯化合物，