公开(公告)号：US20150374778A1

公开(公告)日：2015-12-31

申请号：US14846786

申请日：2015-09-06

申请人： Mingchun Xiao

发明人： Mingchun Xiao

IPC分类号： A61K36/9068 ,  A61K36/8988 ,  A61K36/07 ,  A61K36/752 ,  A61K36/284 ,  A61K36/484 ,  A61K36/575 ,  A61K36/236 ,  A61K36/232 ,  A61K36/237 ,  A61K36/268 ,  A61K36/85 ,  A61K36/185 ,  A61K36/46 ,  A61K36/21 ,  A61K36/515 ,  A61K36/54 ,  A61K36/258 ,  A61K36/65 ,  A61K36/804 ,  A61K36/481 ,  A61K36/714 ,  A61K36/12 ,  A61K36/884 ,  A61K36/8945 ,  A61K36/882 ,  A61K36/9062 ,  A61K36/734 ,  A61K36/8888

CPC分类号： A61K36/9068 ,  A23F3/163 ,  A61K36/07 ,  A61K36/076 ,  A61K36/12 ,  A61K36/185 ,  A61K36/21 ,  A61K36/232 ,  A61K36/233 ,  A61K36/236 ,  A61K36/237 ,  A61K36/258 ,  A61K36/268 ,  A61K36/284 ,  A61K36/46 ,  A61K36/48 ,  A61K36/481 ,  A61K36/482 ,  A61K36/484 ,  A61K36/515 ,  A61K36/53 ,  A61K36/532 ,  A61K36/535 ,  A61K36/538 ,  A61K36/539 ,  A61K36/54 ,  A61K36/575 ,  A61K36/65 ,  A61K36/66 ,  A61K36/68 ,  A61K36/71 ,  A61K36/714 ,  A61K36/734 ,  A61K36/752 ,  A61K36/804 ,  A61K36/85 ,  A61K36/88 ,  A61K36/882 ,  A61K36/884 ,  A61K36/888 ,  A61K36/8884 ,  A61K36/8888 ,  A61K36/8905 ,  A61K36/8945 ,  A61K36/8988 ,  A61K36/8998 ,  A61K36/906 ,  A61K36/9062 ,  A61K36/9064 ,  A61K36/9066 ,  A61K2300/00

摘要： A pharmaceutical composition for treating cancers and preparation method thereof. Said composition for treating cancers contains Chinese medicinal materials including Rhizoma Pinelliae, Rhizoma Arisaematis, Rhizoma Gastrodiae etc., and said preparation method is in accordance with a conventional Chinese medicinal preparation method, manufacturing said composition to form any one of the ordinary oral preparations.

摘要翻译： 一种治疗癌症的药物组合物及其制备方法。 所述治疗癌症的组合物含有中药材，包括苦参，苦参，天麻等，所述制备方法按照常规的中药制备方法，制备所述组合物以形成任何一种普通口服制剂。

公开(公告)号：US20150320819A1

公开(公告)日：2015-11-12

申请号：US14273810

申请日：2014-05-09

申请人： Joon-Sik SHIN

发明人： Joon-Sik SHIN ,  Jin Ho LEE

IPC分类号： A61K36/65 ,  A61K36/484 ,  A61K36/21 ,  A61K36/12 ,  A61K36/23

CPC分类号： A61K36/65 ,  A61K36/11 ,  A61K36/12 ,  A61K36/21 ,  A61K36/23 ,  A61K36/238 ,  A61K36/484 ,  A61K2236/00 ,  A61K2300/00

摘要： The present invention relates to a method for treating inflammation, arthritis or disc diseases using a pharmaceutically effective amount of a mixed extract of Cibotii Rhizoma, Ledebouriellae Radix, Achyranthis Radix, Paeonia lactiflora Pall, and Glycyrrhizae Radix according to the present invention, and since the mixed extract of Cibotii Rhizoma, Ledebouriellae Radix, Achyranthis Radix, Paeonia lactiflora Pall, and Glycyrrhizae Radix increased the survival rate of macrophages in vitro, decreased the production of NO, which is involved in anti-inflammation, inhibited all of COX-2, iNOS and MMP expressions, showed nerve cell regenerative and protective effects, exhibited pain-inhibitory effect and arthritis edema-inhibitory effects in vivo, and showed disc volume decrease and absorption effect in patients of disc diseases, the mixed extract of Cibotii Rhizoma, Ledebouriellae Radix, Achyranthis Radix, Paeonia lactiflora Pall, and Glycyrrhizae Radix could be used effectively for methods for treating inflammation, arthritis, or disc diseases.

摘要翻译： 本发明涉及使用药用有效量的根据本发明的西伯利亚根瘤菌，白芝麻，白芷，芍药和甘草的混合提取物治疗炎症，关节炎或椎间盘疾病的方法， C OS all all OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS OS MMP表达显示神经细胞再生和保护作用，在体内表现出止痛作用和关节炎水肿抑制作用，并显示椎间盘疾病患者椎间盘减少和吸收效果，Cibotii Rhizoma，Ledebouriellae Radix的混合提取物， Achyranthis Radix，Paeonia lactiflora Pall和Glycyrrhizae Radix可以有效地用于方法f 或治疗炎症，关节炎或椎间盘疾病。

公开(公告)号：US20150190441A1

公开(公告)日：2015-07-09

申请号：US14665538

申请日：2015-03-23

申请人： JIN XIN BIOTECHNOLOGY CO., LTD. ,  ACADEMIA SINICA

发明人： Kun-Hsuan Huang ,  Tza-Zen Chaung ,  Pei-Wen Hsiao ,  Chia-Jui Tsai

IPC分类号： A61K36/12 ,  A61K31/23 ,  A61K31/231 ,  A61K31/409 ,  A61K31/232

CPC分类号： A61K36/12 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/23 ,  A61K31/231 ,  A61K31/232 ,  A61K31/409 ,  A23V2200/30

摘要： An extract of Asplenium nidus L. includes pyropheophorbide a methyl ester (C34H36N4O3), pheophorbide a methyl ester (C35H36N4O5), 1-linleoyl-3-linolenoyl-glycerol (C39H66O5), 1-linleoyl-2,3-dipalmitoyl-rac-glycerol (C53H98O6) and 1,3-dipalmitoyl-sn-glycerol (C35H68O5). The extract of Asplenium nidus L. is obtained by using a method including steps of: solvent extraction, using an solvent to extract an Asplenium nidus L. sample and to obtain an extract, with a w/v ratio between the solvent and the Asplenium nidus L. sample being 50˜60 mg/ml; and column chromatography, fractionating the extract with water and ethanol as eluent to obtain several fractions including fraction a to fraction i, and further evaporating and lyophilizing fraction b, c, d or their combination to obtain an extract of Asplenium nidus L.

摘要翻译： of藜提取物包括焦脱镁叶酸甲酯（C34H36N4O3），偏硼酸甲酯（C35H36N4O5），1-亚麻酰-3-亚油酸 - 甘油（C39H66O5），1-亚麻酰基-2,3-二棕榈酰基 - 外消旋甘油 （C53H98O6）和1,3-二棕榈酰基-sn-甘油（C35H68O5）。 通过使用以下方法获得of The提取物，该方法包括以下步骤：溶剂萃取，使用溶剂萃取an an L. L. L. L. L. and and and and L L L L L L L L L L L L L 样品为50〜60mg / ml; 和柱色谱法，用水和乙醇作为洗脱液将提取物分馏，得到几种级分，包括级分a至级分i，并进一步蒸发和冻干级分b，c，d或其组合，得到As an提取物。

公开(公告)号：US20140377386A1

公开(公告)日：2014-12-25

申请号：US14305876

申请日：2014-06-16

申请人： Jatinder Rana ,  Russell Keith Randolph ,  Jeffrey Scholten ,  MyPhuong Thi Le ,  Richard J. Johnson ,  Miguel Angel Lanaspa Garcia

发明人： Jatinder Rana ,  Russell Keith Randolph ,  Jeffrey Scholten ,  MyPhuong Thi Le ,  Richard J. Johnson ,  Miguel Angel Lanaspa Garcia

IPC分类号： A61K36/73 ,  A61K36/38 ,  A61K36/185 ,  A61K36/487 ,  A61K36/539 ,  A61K36/12 ,  A61K36/19 ,  A61K36/62 ,  A61K36/75 ,  A61K36/23 ,  A61K36/605 ,  A61K36/232 ,  A61K36/44

CPC分类号： A61K36/73 ,  A61K36/12 ,  A61K36/185 ,  A61K36/19 ,  A61K36/23 ,  A61K36/232 ,  A61K36/38 ,  A61K36/44 ,  A61K36/487 ,  A61K36/539 ,  A61K36/605 ,  A61K36/62 ,  A61K36/75

摘要： A composition for inhibiting ketohexokinase, for example, ketohexokinase-C (KHK-C) activity, may include a plant extract exhibiting at least IC50 (i.e., 50% KHK-C inhibition at a concentration in the range of from about 0.1 μg/mL to about 1000 μg/mL. The composition may be in a form suitable for oral ingestion. A method for inhibiting KHK-C activity in a subject may include administering a plant extract that exhibits at least 50% KHK-C inhibition at a concentration from about 0.1 μg/mL to about 1000 μg/mL. The administering may be done to treat or prevent at least one of sugar addiction, obesity, or metabolic syndrome. The administering may be done to provide a diminished craving in the subject from at least one member selected from the group consisting of craving of sugar, fructose, fructose-containing sugars, carbohydrates, and combinations thereof. The subject may be pre-diabetic, diabetic and or insulin resistant.

摘要翻译： 用于抑制酮基己糖激酶的组合物，例如酮基己糖激酶-C（KHK-C）活性，可以包括至少具有IC 50的植物提取物（即，浓度在约0.1μg/ mL范围内的50％KHK-C抑制 约1000μg/ mL，组合物可以是适合于口服摄取的形式，抑制受试者中KHK-C活性的方法可包括给予至少50％KHK-C抑制的植物提取物，浓度为 约0.1μg/ mL至约1000μg/ mL，可以进行给药以治疗或预防糖成瘾，肥胖症或代谢综合征中的至少一种。施用可以至少从受试者中提供减少的渴望 选自糖，果糖，含果糖的糖，碳水化合物及其组合的组中的一个成员，所述受试者可以是糖尿病前期，糖尿病和/或胰岛素抵抗。

公开(公告)号：US20140017348A1

公开(公告)日：2014-01-16

申请号：US14032556

申请日：2013-09-20

申请人： Ethicon, Inc.

发明人： Yi-Lan Wang ,  Xintian Ming

IPC分类号： A61K36/12 ,  A61K9/00

CPC分类号： A61K36/12 ,  A61K9/0014 ,  A61K36/287 ,  A61K38/39 ,  A61L26/0038 ,  A61L26/0057 ,  A61L2400/04 ,  A61K2300/00

摘要： The present invention relates generally to agents and devices for promoting hemostasis and, more particularly, to an extract of a plant-based “Traditional Chinese Medicinal” product and devices incorporating such agents for the delivery thereof to bleeding wounds.

摘要翻译： 本发明一般涉及用于促进止血的药剂和装置，更具体地，涉及植物性“中药”产品的提取物和包含用于将其输送给出血伤口的药剂的提取物。

公开(公告)号：US06855347B2

公开(公告)日：2005-02-15

申请号：US10103738

申请日：2002-03-25

申请人： Janaswamy Madhusudana Rao ,  Upparapalli Sampathkumar ,  Boggavarapu Subrahmanya Sastry ,  Jhillu Singh Yadav ,  Kondapuram Vijaya Raghavan ,  Gautam Palit ,  Deepak Rai ,  Panniyampally Madhavankutty Varier ,  Trikovil Sankaran Muraleedharan ,  Kollath Muraleedharan

发明人： Janaswamy Madhusudana Rao ,  Upparapalli Sampathkumar ,  Boggavarapu Subrahmanya Sastry ,  Jhillu Singh Yadav ,  Kondapuram Vijaya Raghavan ,  Gautam Palit ,  Deepak Rai ,  Panniyampally Madhavankutty Varier ,  Trikovil Sankaran Muraleedharan ,  Kollath Muraleedharan

IPC分类号： A01N65/00 ,  A61K36/12 ,  A61K36/185 ,  A61K36/58 ,  A61K36/67 ,  A61K36/75 ,  A61K36/81 ,  A61K36/87 ,  A61K36/9068 ,  A61K35/78

CPC分类号： A61K36/12 ,  A61K36/185 ,  A61K36/58 ,  A61K36/67 ,  A61K36/75 ,  A61K36/81 ,  A61K36/87 ,  A61K36/9068 ,  Y10S514/925 ,  Y10S514/926 ,  Y10S514/927 ,  A61K2300/00

摘要： The present invention relates to a novel synergistic herbal composition for the treatment of gastric ulcer, a method for preparing said synergistic herbal composition and a process for the treatment of gastric ulcer using said composition and more particularly, the present invention relates to a novel synergistic herbal composition which is effective against pyloric ligation induced ulcer model and histamine induced ulcer model.

摘要翻译： 本发明涉及一种用于治疗胃溃疡的新型协同草药组合物，一种制备所述协同草药组合物的方法和使用所述组合物治疗胃溃疡的方法，更具体地说，本发明涉及一种新型协同草药 对幽门结扎诱导的溃疡模型和组胺诱导的溃疡模型有效的组合物。

公开(公告)号：US4944946A

公开(公告)日：1990-07-31

申请号：US396331

申请日：1989-08-21

申请人： Yaguang Liu

发明人： Yaguang Liu

IPC分类号： A61K31/715 ,  A61K36/12 ,  A61K36/287 ,  A61K36/315 ,  A61K36/481 ,  C08B37/00

CPC分类号： C08B37/00 ,  A61K31/715 ,  A61K36/12 ,  A61K36/287 ,  A61K36/315 ,  A61K36/481

摘要： A safe pharmaceutical composition for treatment and prevention of infections caused by viruses and increasing immune function. The pharmaceutical composition is composed of four active ingredients: Polysaccharides of Wang Qi, Banlankensu, Yejuhua-flavonoid and Guanzhongsu and method of making the same.

公开(公告)号：US4944945A

公开(公告)日：1990-07-31

申请号：US396332

申请日：1989-08-21

申请人： Yaguang Lui

发明人： Yaguang Lui

IPC分类号： A61K31/715 ,  A61K36/12 ,  A61K36/19 ,  A61K36/28 ,  A61K36/315 ,  A61K36/48 ,  C08B37/00

CPC分类号： C08B37/00 ,  A61K31/715 ,  A61K36/12 ,  A61K36/19 ,  A61K36/28 ,  A61K36/315 ,  A61K36/48

摘要： A safe pharmaceutical composition for treatment and prevention of infections caused by viruses and increasing immune function. The pharmaceutical composition is composed of four active ingredients: Polysaccharides of Wang Qi, Banlankensu, Yejuhua-flavonoid and Guanzhongsu and method of making the same.

摘要翻译： 用于治疗和预防由病毒引起的感染和增加免疫功能的安全药物组合物。 药物组合物由王琦，班兰蔻，叶菊华，关中等多种活性成分组成，制成方法。