公开(公告)号：US20240216322A1

公开(公告)日：2024-07-04

申请号：US18603789

申请日：2024-03-13

Applicant: AMARIN PHARMACEUTICALS IRELAND LIMITED

Inventor： Jonathan Rowe

IPC: A61K31/232 ,  A61K9/00 ,  A61K9/48 ,  A61K31/20 ,  A61K31/202 ,  A61K31/355 ,  A61K45/06 ,  A61K47/22 ,  A61P3/06

CPC classification number: A61K31/232 ,  A61K9/0053 ,  A61K9/48 ,  A61K9/4808 ,  A61K9/4816 ,  A61K9/4825 ,  A61K31/20 ,  A61K31/202 ,  A61K31/355 ,  A61K45/06 ,  A61K47/22 ,  A61P3/06

Abstract: In various embodiments, the present invention provides pharmaceutical compositions comprising fatty acids and methods for treating subjects using same.

公开(公告)号：US20240197666A1

公开(公告)日：2024-06-20

申请号：US18283787

申请日：2022-03-23

Applicant: K-Gen Therapeutics, Inc.

Inventor： Chun Jiang ,  Ruihong CHEN

IPC: A61K31/22 ,  A61K31/122 ,  A61K31/222 ,  A61K31/223 ,  A61K31/23 ,  A61K31/232 ,  A61K31/336 ,  A61K31/397 ,  A61K31/405 ,  A61K31/415 ,  A61K31/421 ,  A61K31/426 ,  A61K31/437 ,  A61K31/4409 ,  A61K39/395 ,  A61K45/06 ,  A61P17/02 ,  A61P35/00 ,  A61K39/00

CPC classification number: A61K31/22 ,  A61K31/122 ,  A61K31/222 ,  A61K31/223 ,  A61K31/23 ,  A61K31/232 ,  A61K31/336 ,  A61K31/397 ,  A61K31/405 ,  A61K31/415 ,  A61K31/421 ,  A61K31/426 ,  A61K31/437 ,  A61K31/4409 ,  A61K39/3955 ,  A61K45/06 ,  A61P17/02 ,  A61P35/00 ,  A61K2039/505

Abstract: This present disclosure relates to a method of stimulating an immune response using compounds that activate protein kinase C (PKC), including for treatment of a cancer, a precancerous lesion, a benign tumor, or a wound.

公开(公告)号：US11986452B2

公开(公告)日：2024-05-21

申请号：US17723598

申请日：2022-04-19

Applicant: Amarin Pharmaceuticals Ireland Limited

Inventor： Paresh Soni

IPC: A61K31/232 ,  A61P9/10

CPC classification number: A61K31/232 ,  A61P9/10

Abstract: In various embodiments, the present disclosure provides methods reducing the risk of heart failure in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.

公开(公告)号：US11931392B2

公开(公告)日：2024-03-19

申请号：US17394047

申请日：2021-08-04

Applicant: Chun-Sheng Kuo

Inventor： Chun-Sheng Kuo

IPC: A61K36/575 ,  A61K31/015 ,  A61K31/045 ,  A61K31/232 ,  A61P35/00

CPC classification number: A61K36/575 ,  A61K31/015 ,  A61K31/045 ,  A61K31/232 ,  A61P35/00

Abstract: A use of Magnolia figo extract in the manufacture of a compound for inhibiting growth of lung cancer cells.

公开(公告)号：US11911480B2

公开(公告)日：2024-02-27

申请号：US16931592

申请日：2020-07-17

Applicant: MOCHIDA PHARMACEUTICAL CO., LTD.

Inventor： Hiromitsu Ito ,  Hirosato Fujii ,  Motoo Yamagata

IPC: A61K47/44 ,  A23L33/12 ,  A61K9/00 ,  A61K9/107 ,  A61K9/48 ,  A61K31/202 ,  A61K31/232 ,  A61K47/24 ,  A61K47/26

CPC classification number: A61K47/44 ,  A23L33/12 ,  A61K9/0053 ,  A61K9/107 ,  A61K9/1075 ,  A61K9/48 ,  A61K9/4858 ,  A61K9/4866 ,  A61K9/4875 ,  A61K31/202 ,  A61K31/232 ,  A61K47/24 ,  A61K47/26 ,  A23V2002/00

Abstract: A self-emulsifying composition contains: 70 to 90% by weight of at least one compound selected from the group consisting of ω3 polyunsaturated fatty acids and their pharmaceutically acceptable salts and esters; 0.5 to 6% by weight of water; 1 to 29% by weight of a polyoxyethylene sorbitan fatty acid ester as an emulsifier (optionally including a polyoxyl castor oil, and not including lecithin); and lecithin in an amount of 3 to 40 parts by weight in relation to 100 parts by weight of ω3 polyunsaturated fatty acids and the like. The self-emulsifying composition is excellent in self-emulsifying property, composition dispersibility, emulsion stability, and absorbability, is free from ethanol and polyhydric alcohols or only has such an alcohol added thereto at a reduced concentration, and is useful for foods and pharmaceuticals.

公开(公告)号：US20240058293A1

公开(公告)日：2024-02-22

申请号：US18382446

申请日：2023-10-20

Applicant: Emory University ,  Children's Healthcare of Atlanta, Inc.

Inventor： Claudia R. Morris

IPC: A61K31/23 ,  A61K31/202 ,  A61K31/122 ,  A61K31/07 ,  A61K31/59 ,  A61K38/46 ,  A61K31/7004 ,  A61K31/473 ,  A61K35/741 ,  A61K33/26 ,  A61K31/661 ,  A61K33/18 ,  A61K33/34 ,  A61K33/32 ,  A61K33/24 ,  A61K31/047 ,  A61K31/385 ,  A61K31/205 ,  A61K31/375 ,  A61K33/30 ,  A61K31/355 ,  A23L33/175 ,  A23L33/15 ,  A23L33/12 ,  A61K31/22 ,  A61K33/42 ,  A23L33/00 ,  A61K45/06 ,  A23L33/16 ,  A61K31/19 ,  A61K31/4375 ,  A23L33/155 ,  A61K31/231 ,  A61K9/00 ,  A61K31/232 ,  A61K31/20 ,  A23L33/135

CPC classification number: A61K31/23 ,  A61K31/202 ,  A61K31/122 ,  A61K31/07 ,  A61K31/59 ,  A61K38/46 ,  A61K31/7004 ,  A61K31/473 ,  A61K35/741 ,  A61K33/26 ,  A61K31/661 ,  A61K33/18 ,  A61K33/34 ,  A61K33/32 ,  A61K33/24 ,  A61K31/047 ,  A61K31/385 ,  A61K31/205 ,  A61K31/375 ,  A61K33/30 ,  A61K31/355 ,  A23L33/175 ,  A23L33/15 ,  A23L33/12 ,  A61K31/22 ,  A61K33/42 ,  A23L33/40 ,  A61K45/06 ,  A23L33/16 ,  A61K31/19 ,  A61K31/4375 ,  A23L33/155 ,  A61K31/231 ,  A61K9/0056 ,  A61K31/232 ,  A61K31/20 ,  A23L33/135 ,  A23V2002/00 ,  A61K2035/115

Abstract: Disclosed are nutritional formulations and uses for treating or preventing a gastrointestinal condition and/or motor-planning speech and/or coordination difficulties. In certain embodiments, the nutritional formulations comprise medium chain fatty acids, or esters thereof (such as and tri-, di-, mono-glycerides, or alkyl esters), unsaturated fatty acids, and a vitamin E and optionally other nutrients. In certain embodiments, any of the compounds or nutrients may be in alternative salt forms.

公开(公告)号：US20230330168A1

公开(公告)日：2023-10-19

申请号：US18134050

申请日：2023-04-13

Applicant: South China Agricultural University

Inventor： Bing Du ,  Dong Peng ,  Pan Li ,  Shaojie Huang

IPC: A23L33/105 ,  A23L33/12 ,  A61K36/752 ,  A61K36/47 ,  A23L33/00 ,  A61K31/232 ,  A61P27/04

CPC classification number: A61K36/47 ,  A23L33/105 ,  A23L33/12 ,  A23L33/40 ,  A61K31/232 ,  A61K36/752 ,  A61P27/04

Abstract: The present disclosure discloses a composition for improving eyesight, and relates to the technical field of food. The composition comprises Plukenetia volubilis oil, citri reticulatae pericarpium oil, and lutein ester. The composition canbe prepared into a powder, a tablet, a capsule, a granule, an oral preparation, and a dripping pill. The composition can effectively relieve asthenopia, prevent impaired vision, and improve eyesight, and has a good market prospect.

公开(公告)号：US11712428B2

公开(公告)日：2023-08-01

申请号：US17087759

申请日：2020-11-03

Applicant: Amarin Pharmaceuticals Ireland Limited

Inventor： Ian Osterloh ,  Pierre Wicker ,  Rene Braeckman ,  Paresh Soni ,  Jonathan Rowe

IPC: A61K31/232 ,  A61K31/202 ,  A61K31/355 ,  A61K45/06 ,  A61P3/06 ,  A61P9/12 ,  A61P9/14 ,  A61K9/48

CPC classification number: A61K31/232 ,  A61K31/202 ,  A61K31/355 ,  A61K45/06 ,  A61P3/06 ,  A61P9/12 ,  A61P9/14 ,  A61K9/4875 ,  A61K31/355 ,  A61K2300/00 ,  A61K31/202 ,  A61K2300/00 ,  A61K31/232 ,  A61K2300/00

Abstract: In various embodiments, the present invention provides pharmaceutical compositions and methods for treating cardiovascular-related disease.

公开(公告)号：US20230218560A1

公开(公告)日：2023-07-13

申请号：US18110954

申请日：2023-02-17

Applicant: Pronova Biopharma Norge As

Inventor： Svein Olaf HUSTVEDT ,  Preben Houlberg Olesen ,  Gunnar Berge ,  Jo Erik Johnsrud Klaveness

IPC: A61K31/232 ,  A61K9/48 ,  A61K31/202 ,  A61K9/08 ,  A61K9/20 ,  A23L33/115 ,  A23L33/10 ,  A61K31/557 ,  A61K31/201 ,  A61K9/107

CPC classification number: A61K31/232 ,  A61K9/4858 ,  A61K31/202 ,  A61K9/08 ,  A61K9/4866 ,  A61K9/20 ,  A23L33/115 ,  A23L33/10 ,  A61K9/4825 ,  A61K31/557 ,  A61K31/201 ,  A61K9/1075

Abstract: A preconcentrate comprising a fatty acid oil mixture that contains EPA and DHA, preferably in the form of ethyl ester or triglyceride, and at least one surfactant. The preconcentrates are capable of forming a self-nanoemulsifying drug delivery system, a self-microemulsifying drug delivery system or a self-emulsifying drug delivery system (SNEDDS, SMEDDS or SEDDS) in an aqueous solution. The application is also directed to a food supplement preconcentrate.

公开(公告)号：US20230210806A1

公开(公告)日：2023-07-06

申请号：US17884680

申请日：2022-08-10

Applicant: Amarin Pharmaceuticals Ireland Limited

Inventor： Ian Osterloh ,  Pierre Wicker ,  Rene Braeckman ,  Paresh Soni ,  Mehar Manku

IPC: A61K31/232 ,  A61P9/10 ,  C07C57/03 ,  A61P3/06 ,  A61K31/202 ,  A61K31/366 ,  A61K31/40 ,  A61K31/505 ,  A61K9/48

CPC classification number: A61K31/232 ,  A61P9/10 ,  C07C57/03 ,  A61P3/06 ,  A61K31/202 ,  A61K31/366 ,  A61K31/40 ,  A61K31/505 ,  A61K9/48

Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.