公开(公告)号：US11504268B2

公开(公告)日：2022-11-22

申请号：US16019814

申请日：2018-06-27

申请人： Ethicon, Inc.

发明人： Howard Scalzo ,  Xintian Ming ,  Leo B. Kriksunov

IPC分类号： A61F7/02 ,  A61F7/00 ,  A61F13/02 ,  A61F13/00 ,  A61F15/00

摘要： A disposable dressing forms a compartment around and above a wound site and a volatile antimicrobial compound is allowed to sublimate/evaporate into the compartment. A heating element is included in the dressing, with heat stimulating wound healing and simultaneously accelerating sublimation/evaporation of the antimicrobial compound.

公开(公告)号：US20160000609A1

公开(公告)日：2016-01-07

申请号：US14820919

申请日：2015-08-07

申请人： Ethicon, Inc.

发明人： Robert W. Van Holten ,  Xintian Ming ,  Jerome Riebman

IPC分类号： A61F13/00

摘要： The invention relates to a transparent, absorbent device for the dressing of wounds and insertion sites of percutaneous and drug delivery devices. The device provides 360 degree or complete circumferential protection of a wound or insertion site of a percutaneous or drug delivery device and comprises a hydrogel center and at least one absorbent material. The hydrogel center can optionally comprise a bioactive agent(s).

公开(公告)号：US20130196052A1

公开(公告)日：2013-08-01

申请号：US13801719

申请日：2013-03-13

申请人： ETHICON, INC.

发明人： Henry Pokropinski, JR. ,  Jerome A. Fischer ,  Jerry Jonn ,  Huimin Wang ,  Stephen Rothenburger ,  Xintian Ming

IPC分类号： A61L17/00

CPC分类号： A61L17/005 ,  A61L17/145 ,  A61L24/0015 ,  A61L27/34 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/404 ,  A61L2300/622 ,  Y10T428/2982

摘要： An antimicrobial composition for coating a medical device. The antimicrobial composition includes a polymeric film forming material and an antimicrobial agent comprising a material selected from the group of extract of Houttuynia cordata, sodium houttuyfonate, sodium new houttuyfonate and mixtures thereof. A medical device having an antimicrobial composition that includes a material selected from the group of extract of Houttuynia cordata, sodium houttuyfonate, sodium new houttuyfonate and mixtures thereof and a method for making same are also provided.

摘要翻译： 一种用于涂覆医疗装置的抗微生物组合物。 抗微生物组合物包括聚合物成膜材料和抗微生物剂，其包含选自鱼腥草提取物，氢化，，酸钠，新型ho，酸钠及其混合物的组合物。 本发明提供一种具有抗微生物组合物的医疗装置，其特征在于，具有选自鱼腥草提取物，氢化，，酸钠，新ho，酸钠及其混合物的物质及其制造方法。

公开(公告)号：US20130251774A1

公开(公告)日：2013-09-26

申请号：US13900519

申请日：2013-05-22

申请人： Ethicon, Inc.

发明人： Joerg Priewe ,  Xintian Ming

IPC分类号： A61L31/04 ,  A61F2/12

CPC分类号： A61L31/047 ,  A61F2/12 ,  A61K31/549 ,  A61K38/16 ,  A61K45/06 ,  A61K2300/00

摘要： Novel antimicrobial compositions and coatings are disclosed. The antimicrobial compositions consist of mixtures of taurolidine and protamine, including protamine salts. The antimicrobial compositions are particularly useful in coatings for implantable medical devices. The antimicrobial compositions are effective against a broad spectrum of microbes.

公开(公告)号：US10667956B2

公开(公告)日：2020-06-02

申请号：US14820919

申请日：2015-08-07

申请人： Ethicon, Inc.

发明人： Robert W. Van Holten ,  Xintian Ming ,  Jerome Riebman

IPC分类号： A61F13/00 ,  A01N25/04 ,  A01N25/34 ,  A01N31/02 ,  A61K31/155

摘要： The invention relates to a transparent, absorbent device for the dressing of wounds and insertion sites of percutaneous and drug delivery devices. The device provides 360 degree or complete circumferential protection of a wound or insertion site of a percutaneous or drug delivery device and comprises a hydrogel center and at least one absorbent material. The hydrogel center can optionally comprise a bioactive agent(s).

公开(公告)号：US10022411B2

公开(公告)日：2018-07-17

申请号：US14032556

申请日：2013-09-20

申请人： Ethicon, Inc.

发明人： Yi-Lan Wang ,  Xintian Ming

IPC分类号： A61K36/12 ,  A61K36/00 ,  A61K36/287 ,  A61K9/00 ,  A61K38/39 ,  A61L26/00

摘要： The present invention relates generally to agents and devices for promoting hemostasis and, more particularly, to an extract of a plant-based “Traditional Chinese Medicinal” product and devices incorporating such agents for the delivery thereof to bleeding wounds.

公开(公告)号：US09205179B2

公开(公告)日：2015-12-08

申请号：US13900519

申请日：2013-05-22

申请人： Ethicon, Inc.

发明人： Joerg Priewe ,  Xintian Ming

IPC分类号： A01N37/18 ,  A01N59/16 ,  A01N59/04 ,  A01N25/34 ,  B05D7/00 ,  A01N25/08 ,  A01P1/00 ,  A61P31/00 ,  A61K38/17 ,  B05D5/00 ,  A01N59/20 ,  A01N25/10 ,  A61L31/04 ,  A61K38/16 ,  A61K31/549 ,  A61F2/12 ,  A61K45/06

CPC分类号： A61L31/047 ,  A61F2/12 ,  A61K31/549 ,  A61K38/16 ,  A61K45/06 ,  A61K2300/00

摘要： Novel antimicrobial compositions and coatings are disclosed. The antimicrobial compositions consist of mixtures of taurolidine and protamine, including protamine salts. The antimicrobial compositions are particularly useful in coatings for implantable medical devices. The antimicrobial compositions are effective against a broad spectrum of microbes.

摘要翻译： 公开了新型抗微生物组合物和涂层。 抗微生物组合物由taurolidine和鱼精蛋白的混合物组成，包括鱼精蛋白盐。 抗微生物组合物特别适用于可植入医疗器械的涂层。 抗微生物组合物对广谱的微生物有效。

公开(公告)号：US20140017348A1

公开(公告)日：2014-01-16

申请号：US14032556

申请日：2013-09-20

申请人： Ethicon, Inc.

发明人： Yi-Lan Wang ,  Xintian Ming

IPC分类号： A61K36/12 ,  A61K9/00

CPC分类号： A61K36/12 ,  A61K9/0014 ,  A61K36/287 ,  A61K38/39 ,  A61L26/0038 ,  A61L26/0057 ,  A61L2400/04 ,  A61K2300/00

摘要： The present invention relates generally to agents and devices for promoting hemostasis and, more particularly, to an extract of a plant-based “Traditional Chinese Medicinal” product and devices incorporating such agents for the delivery thereof to bleeding wounds.

摘要翻译： 本发明一般涉及用于促进止血的药剂和装置，更具体地，涉及植物性“中药”产品的提取物和包含用于将其输送给出血伤口的药剂的提取物。