公开(公告)号：US20220257685A1

公开(公告)日：2022-08-18

申请号：US17618013

申请日：2020-06-11

Applicant: VALBIOTIS

Inventor： Sébastien PELTIER ,  Pascal SIRVENT ,  Yolanda OTERO

IPC: A61K36/287 ,  A61K36/28 ,  A61K36/45 ,  A61K31/7048 ,  A61K45/06 ,  A61P1/12

Abstract: The invention relates to a composition comprising at least: an extract of Chrysanthellum, and an extract of artichoke, and an extract of blueberry, and an extract of at least one plant-derived raw material comprising oleuropein, and optionally synthetic piperine and/or an extract of at least one plant-derived raw material comprising piperine, for use as a drug or nutritional product in the prevention and/or treatment of chronic inflammatory bowel disease in humans or animals.

公开(公告)号：US20210361733A1

公开(公告)日：2021-11-25

申请号：US17395491

申请日：2021-08-06

Applicant: Atta-ur- Rahman ,  Muhammad Iqbal Choudhary ,  Saba Farooq ,  Atia-tul- Wahab

Inventor： Atta-ur- Rahman ,  Muhammad Iqbal Choudhary ,  Saba Farooq ,  Atia-tul- Wahab

IPC: A61K36/534 ,  A61K36/287 ,  A61P31/14

Abstract: Due to the SARS-CoV-2 pandemic, the development and screening of novel antiviral agents are urgently required. Herein, we developed herbal extracts with promising antiviral activity against SARS-CoV-2. Antiviral effects of Mentha piperita, and Flos chrysanthemi extracts alone, in combination and their fractions were found to decrease viral load. To determine which step of the virus is inhibited by the treatment, the extracts were administered at different time points of treatment, namely prophylactic (Full-time), pre-adsorption (Entry), and post adsorption (Post-entry). Most of the fractions, exhibited high efficacy upon prophylactic administration. The viral load was lower in prophylactic-treated cells than in non-treated cells. Administration of combinations, following 2:1 molar ratio of Mentha piperita, and Flos chrysanthemi significantly reduced the viral load by increasing the Cq values. Ethyl acetate extract of Mentha piperita and hexanes extract of Flos chrysanthemi were found to be most effective at all treatment points.

公开(公告)号：US10813965B2

公开(公告)日：2020-10-27

申请号：US15769876

申请日：2016-10-20

Applicant: VALBIOTIS ,  Universite Clermont Auvergne

Inventor： Sebastien Peltier ,  Vivien Chavanelle ,  Pascal Sirvent

IPC: A61K36/00 ,  A61K36/287 ,  A61K36/815 ,  A61K36/28 ,  A61K36/63 ,  A61K9/00 ,  A61K9/20 ,  A61K36/45 ,  A23L33/105 ,  A61P3/06 ,  A61P3/10 ,  A61K9/48 ,  A61K31/197 ,  A61K31/4188 ,  A61K31/4525 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/525 ,  A61K31/593 ,  A61K31/675 ,  A61K31/714 ,  A61K33/24 ,  A61K33/30 ,  A61K35/747 ,  A61K36/67 ,  A61K45/06 ,  A61K35/00

Abstract: A composition comprising at least a mixture of molecules extracted from Chrysanthellum indicum, Cynara scolymus and Lycium barbarum. This composition is in particular useful as a nutritional product or health product to prevent and/or combat fat and/or carbohydrate metabolism disorders in Humans or animals.

公开(公告)号：US20200009208A1

公开(公告)日：2020-01-09

申请号：US16474528

申请日：2017-11-30

Applicant: Industry-Academic Cooperation Foundation, Yonsei University ,  Cosmax NBT, Inc. ,  Cosmax NS, Inc.

Inventor： Jae Kwan HWANG ,  Jun Gon YUN ,  Mi Bo KIM ,  Chang Hee KIM ,  Joon Hyung LEE ,  Do Wan KWON ,  Su Young CHOI ,  Jin Hak KIM ,  Ji Hwan JANG ,  Jeong Ho GEUM ,  Min Son KWEON

IPC: A61K36/287 ,  A61K31/216 ,  A23L33/105 ,  A61K8/9789 ,  A61K8/37

Abstract: The present invention relates to a composition for preventing or treating a muscle disorder, which includes a chrysanthemum extract or 3,5-dicaffeoylquinic acid as an active ingredient, and specifically, it may be used to reduce mRNA expression of atrogin-1 and MuRF1, which are main biomarkers involved in muscle protein degradation and increase mRNA expression of the mTOR protein, which is a main biomarker involved in muscle protein formation, and myogenin and MyoD, which are biomarkers related to muscle differentiation, thereby reducing muscle loss, and thus the chrysanthemum extract or 3,5-dicaffeoylquinic acid can be used in prevention and treatment of a muscle disorder, or improvement in muscle function. In addition, the chrysanthemum extract or 3,5-dicaffeoylquinic acid increases the activity of SIRT1 and PGC-1α, which are the main biomarkers involved in exercise performance, thereby excellently enhancing exercise performance. In addition, the present invention is a natural substance and may be safely used without a side effect, and therefore may be used as a medication, food or a cosmetic.

公开(公告)号：US20190328813A1

公开(公告)日：2019-10-31

申请号：US16462073

申请日：2017-09-11

Applicant: ANGANG ZUO ,  SHIXU ZUO ,  NA ZHAO

Inventor： ANGANG ZUO ,  SHIXU ZUO ,  NA ZHAO

IPC: A61K36/481 ,  A61K36/287 ,  A61K36/355 ,  A61K36/534 ,  A61K36/074 ,  A61K36/284 ,  A61K36/54 ,  A61K36/61 ,  A61K36/236 ,  A61K36/285 ,  A61K36/484 ,  A61P35/00

Abstract: Disclosed are a traditional Chinese medicine composition for treating tumours and a preparation method therefor, wherein the composition is prepared from Sophora flavescens, wild chrysanthemum flower, honeysuckle, mint, Poria cocos, Atractylodes lancea, cinnamon, clove, Astragalus, Ganoderma lucidum, Ligusticum striatum, Aucklandia root and Radix glycyrrhizae. The traditional Chinese medicine composition has an anti-tumour effect.

公开(公告)号：US20190290478A1

公开(公告)日：2019-09-26

申请号：US16362654

申请日：2019-03-24

Applicant: I-Szu Hsia

Inventor： I-Szu Hsia

IPC: A61F7/00 ,  A61F7/02 ,  A61K36/815 ,  A61K36/287 ,  A61P27/02 ,  A61K9/00

Abstract: An apparatus that includes a frame is for securely holding the medication pad with a moisturized medication compartment held by a holder. The frame holds the medication pad to apply the medication to the eyes wherein the frame further includes a controllable heating element for heating the medication pad. The medication pad further comprises a moisturized compartment containing moisturized extracts of herbal medication for generating and applying a medication steam to the eyes when the heating element is controlled to apply heat to the medication pad.

公开(公告)号：US20180311294A1

公开(公告)日：2018-11-01

申请号：US15769876

申请日：2016-10-20

Applicant: VALBIOTIS ,  UNIVERSITE CLERMONT AUVERGNE

Inventor： Sebastien Peltier ,  Vivien Chavanelle ,  Pascal Sirvent

IPC: A61K36/287 ,  A61K36/28 ,  A61K36/815 ,  A61K36/67 ,  A61K31/4525 ,  A61K36/63 ,  A61K45/06 ,  A61P3/06 ,  A61P3/10 ,  A61K31/51 ,  A61K31/525 ,  A61K31/455 ,  A61K31/197 ,  A61K31/675 ,  A61K31/4188 ,  A61K31/519 ,  A61K31/714 ,  A61K31/593 ,  A61K33/30 ,  A61K33/24 ,  A61K9/20 ,  A61K9/00 ,  A61K35/747 ,  A61K9/48 ,  A23L33/105

Abstract: A composition comprising at least a mixture of molecules extracted from Chrysanthellum indicum, Cynara scolymus and Lycium barbarum. This composition is in particular useful as a nutritional product or health product to prevent and/or combat fat and/or carbohydrate metabolism disorders in Humans or animals.

公开(公告)号：US10022411B2

公开(公告)日：2018-07-17

申请号：US14032556

申请日：2013-09-20

Applicant: Ethicon, Inc.

Inventor： Yi-Lan Wang ,  Xintian Ming

IPC: A61K36/12 ,  A61K36/00 ,  A61K36/287 ,  A61K9/00 ,  A61K38/39 ,  A61L26/00

Abstract: The present invention relates generally to agents and devices for promoting hemostasis and, more particularly, to an extract of a plant-based “Traditional Chinese Medicinal” product and devices incorporating such agents for the delivery thereof to bleeding wounds.

公开(公告)号：US10022410B2

公开(公告)日：2018-07-17

申请号：US12975589

申请日：2010-12-22

Applicant: Yi-Lan Wang ,  Xintian Ming

Inventor： Yi-Lan Wang ,  Xintian Ming

IPC: A61K36/12 ,  A61K36/00 ,  A61K36/287 ,  A61K9/00 ,  A61K38/39 ,  A61L26/00

Abstract: The present invention relates generally to agents and devices for promoting hemostasis and, more particularly, to an extract of a plant-based “Traditional Chinese Medicinal” product and devices incorporating such agents for the delivery thereof to bleeding wounds.

公开(公告)号：US20170354703A1

公开(公告)日：2017-12-14

申请号：US15539239

申请日：2015-12-18

Applicant: KOREA INSTITUTE OF ORIENTAL MEDICINE

Inventor： Dong Seon KIM

IPC: A61K36/54 ,  A61K36/287

CPC classification number: A61K36/54 ,  A23L33/105 ,  A61K36/28 ,  A61K36/287 ,  A61K2300/00 ,  A61P19/02 ,  A61P19/06

Abstract: An anti-gout composition including the mixed extract of Chrysanthemum indicum and Cinnamomum cassia as an active ingredient shows substantially greater inhibitory effects on xanthine oxidase than when Chrysanthemum indicum or Cinnamomum cassia is used separately. An animal model treated with the mixed extract of Chrysanthemum indicum and Cinnamomum cassia experienced a decrease in uric acid in serum and in urine. The mixed extract of Chrysanthemum indicum and Cinnamomum cassia is an active ingredient induced from a natural material, and, accordingly, the mixed extract is safe and a source material therefor is easily provided. Accordingly, the mixed extract can be widely used in gout-related industries.