发明申请
- 专利标题： METHOD FOR TREATING INFLAMMATION, ARTHRITIS OR DISC DISEASES USING A MIXED EXTRACT OF CIBOTII RHIZOMA, LEDEBOURIELLAE RADIX, ACHYRANTHIS RADIX, PAEONIA LACTIFLORA PALL AND GLYCYRRHIZAE RADIX
- 专利标题（中）： 使用混合提取物，柠檬酸芽孢杆菌，紫杉醇，甘油三酯和甘氨酸衍生物治疗炎症，脊髓损伤或疾病的方法
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申请号： US14273810申请日： 2014-05-09
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公开(公告)号： US20150320819A1公开(公告)日： 2015-11-12
- 发明人: Joon-Sik SHIN , Jin Ho LEE
- 申请人： Joon-Sik SHIN
- 申请人地址： KR Seoul
- 专利权人： Joon-Sik SHIN
- 当前专利权人： Joon-Sik SHIN
- 当前专利权人地址： KR Seoul
- 主分类号： A61K36/65
- IPC分类号： A61K36/65 ; A61K36/484 ; A61K36/21 ; A61K36/12 ; A61K36/23
摘要：
The present invention relates to a method for treating inflammation, arthritis or disc diseases using a pharmaceutically effective amount of a mixed extract of Cibotii Rhizoma, Ledebouriellae Radix, Achyranthis Radix, Paeonia lactiflora Pall, and Glycyrrhizae Radix according to the present invention, and since the mixed extract of Cibotii Rhizoma, Ledebouriellae Radix, Achyranthis Radix, Paeonia lactiflora Pall, and Glycyrrhizae Radix increased the survival rate of macrophages in vitro, decreased the production of NO, which is involved in anti-inflammation, inhibited all of COX-2, iNOS and MMP expressions, showed nerve cell regenerative and protective effects, exhibited pain-inhibitory effect and arthritis edema-inhibitory effects in vivo, and showed disc volume decrease and absorption effect in patients of disc diseases, the mixed extract of Cibotii Rhizoma, Ledebouriellae Radix, Achyranthis Radix, Paeonia lactiflora Pall, and Glycyrrhizae Radix could be used effectively for methods for treating inflammation, arthritis, or disc diseases.
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