公开(公告)号：US11819529B2

公开(公告)日：2023-11-21

申请号：US17267064

申请日：2019-08-08

Applicant: Tianjin Geonatural Technology Co., Ltd. (CN) ,  Jingjing Cao

Inventor： Jingjing Cao ,  Weiran Cui ,  Yueran Cui

IPC: A61K36/888 ,  A23L33/00 ,  A23P10/22 ,  A23L29/00 ,  A23L19/00 ,  A23L33/15 ,  A61P1/12 ,  A61K36/23 ,  A61K36/725 ,  A61K36/73 ,  A61K36/899 ,  A23L13/10 ,  A23L13/20 ,  A61K35/407

CPC classification number: A61K36/888 ,  A23L13/10 ,  A23L13/20 ,  A23L19/01 ,  A23L29/04 ,  A23L33/15 ,  A23L33/30 ,  A23P10/22 ,  A61K35/407 ,  A61K36/23 ,  A61K36/725 ,  A61K36/73 ,  A61K36/899 ,  A61P1/12

Abstract: Disclosed in the present invention is a composition for treating diarrhea, comprising the following components calculated by weight ratio: Colocasia esculenta and antidiarrheal foods. The composition of the present invention has low cost, available raw materials, is safe and non-toxic, and is suitable for industrial production. The antidiarrheal effect of the product is remarkable. The rehabilitation time for the common diarrhea is 24-48 hours, and for the diarrhea caused by rotavirus is 48-72 hours, and the rehabilitation time is shortened by 2.5 days on average. The effective rate for persistent diarrhea within 5 days is 90.16%. For diarrhea of infants with milk protein allergy during the addition of supplementary feeding, six to eight kinds of foods can be added in one month, and thus the composition is especially suitable for infants and young children.

公开(公告)号：US20180207219A1

公开(公告)日：2018-07-26

申请号：US15745339

申请日：2015-08-31

Applicant: Lei Wang ,  E Li

Inventor： Lei Wang ,  E Li

IPC: A61K36/734 ,  A61K36/62 ,  A61K36/605 ,  A61K36/288 ,  A61K36/899 ,  A61K36/888 ,  A61K36/752 ,  A61P39/02

CPC classification number: A61K36/734 ,  A61K36/00 ,  A61K36/288 ,  A61K36/605 ,  A61K36/62 ,  A61K36/752 ,  A61K36/888 ,  A61K36/899 ,  A61P39/02

Abstract: A Chinese medicine hangover curing agent. The agent is prepared from Chinese Hawthorn, Folium nelumbinis, Folium mori, Taraxaci herba, Lophatheri herba, common duckweed and tangerine leaves.

公开(公告)号：US20170368129A1

公开(公告)日：2017-12-28

申请号：US15381068

申请日：2016-12-15

Applicant: Tianfeng JIANG ,  Zhenghua JIANG ,  Jinrong ZHOU

Inventor： Tianfeng JIANG ,  Zhenghua JIANG ,  Jinrong ZHOU

IPC: A61K36/888 ,  A61K36/74 ,  A61K36/536 ,  A61K36/28 ,  A61K36/185 ,  A61K36/268 ,  A61K36/236 ,  A61K36/232 ,  A61K36/754 ,  A61K36/481

CPC classification number: A61K36/888 ,  A61K36/185 ,  A61K36/232 ,  A61K36/236 ,  A61K36/268 ,  A61K36/28 ,  A61K36/481 ,  A61K36/536 ,  A61K36/74 ,  A61K36/754 ,  A61K2300/00

Abstract: A composition of Chinese medicines for externally treatment for hypertension includes following herbs: evodia rutaecarpa, chuanxiong, sunflower disc, rhizoma typhonii, angelica, prunella vulgaris, taxillus chinenesis, herba siegesbeckiae, chamomile, astragalus, uncaria rhynchophylla, asarum, and burdock, wherein a weight ratio of the composition is: evodia rutaecarpa 40-50, chuanxiong 30-40, sunflower disc 20-30, rhizoma typhonii 20-25, angelica 20-25, prunella vulgaris 20-30, herba siegesbeckiae 20-30, taxillus chinenesis 20-30, chamomile 20-25, astragalus 20-25, uncaria rhynchophylla 20-30, asarum 20-25, and burdock 20-25.

公开(公告)号：US20170360733A1

公开(公告)日：2017-12-21

申请号：US15534319

申请日：2015-12-01

Applicant: NIHON SIZEN HAKKOH CO., LTD.

Inventor： Naoki HIGASHI ,  Masahiro NAKANISHI

IPC: A61K31/198 ,  A23K50/50 ,  A61K36/8998 ,  A61K36/8994 ,  A61K36/899 ,  A61K36/8967 ,  A61K36/8962 ,  A61K36/8945 ,  A61K36/888 ,  A61K36/88 ,  A61K36/87 ,  A61K36/81 ,  A61K36/78 ,  A61K36/752 ,  A61K36/736 ,  A61K36/73 ,  A61K36/605 ,  A61K36/60 ,  A61K36/535 ,  A61K36/52 ,  A61K36/49 ,  A61K36/48 ,  A61K36/44 ,  A61K36/42 ,  A61K36/31 ,  A61K36/282 ,  A61K36/28 ,  A61K36/23 ,  A61K36/185 ,  A61K36/16 ,  A61K36/07 ,  A61K36/03 ,  A61K31/4172 ,  A61K31/405 ,  A61K31/401 ,  A61K31/352 ,  A61K31/194 ,  A61K31/192 ,  A61K31/19 ,  A61K8/99 ,  A61K36/9066 ,  A23L2/52 ,  A23L33/105 ,  A23K10/12 ,  A61K36/9068

CPC classification number: A61K31/198 ,  A23K10/12 ,  A23K50/50 ,  A23L2/52 ,  A23L33/105 ,  A23V2002/00 ,  A61K8/99 ,  A61K31/19 ,  A61K31/192 ,  A61K31/194 ,  A61K31/196 ,  A61K31/197 ,  A61K31/352 ,  A61K31/353 ,  A61K31/401 ,  A61K31/405 ,  A61K31/4172 ,  A61K35/744 ,  A61K36/03 ,  A61K36/062 ,  A61K36/064 ,  A61K36/07 ,  A61K36/16 ,  A61K36/185 ,  A61K36/23 ,  A61K36/28 ,  A61K36/282 ,  A61K36/31 ,  A61K36/39 ,  A61K36/42 ,  A61K36/44 ,  A61K36/48 ,  A61K36/49 ,  A61K36/52 ,  A61K36/535 ,  A61K36/60 ,  A61K36/605 ,  A61K36/73 ,  A61K36/736 ,  A61K36/75 ,  A61K36/752 ,  A61K36/78 ,  A61K36/81 ,  A61K36/87 ,  A61K36/88 ,  A61K36/888 ,  A61K36/8945 ,  A61K36/8962 ,  A61K36/8967 ,  A61K36/899 ,  A61K36/8994 ,  A61K36/8998 ,  A61K36/9066 ,  A61K36/9068

Abstract: An object of the present invention is to provide a senescence retarding agent that delays the onset of senescence symptoms and extends longevity, and is superior in safety. The senescence retarding agent of the present invention that achieves the object is characterized by containing a plant fermentation product as an active ingredient, the plant fermentation product being a mixture of the following: (a) a koji mold-fermented product of one or more kinds of beans and/or cereals selected from the group consisting of barley, black soybean, red rice, black rice, adzuki bean, adlay, Japanese millet, foxtail millet, and millet; (b) a yeast- and/or lactic acid bacterium-fermented product of one or more kinds of fruits selected from the group consisting of mikan (mandarin orange), grape, apple, yama-budo (crimson glory grape), peach, kaki (Japanese persimmon), papaya, nashi (Japanese pear), watermelon, ume (Japanese apricot), fig, karin (Chinese quince), pumpkin, kumquat, yuzu (Chinese lemon), loquat, apricot, jujube, chestnut, matatabi (silvervine), and sumomo (Japanese plum); (c) a yeast- and/or lactic acid bacterium-fermented product of one or more kinds of root crops and/or potatoes selected from the group consisting of murasaki-imo (purple sweet potato), kikuimo (Jerusalem artichoke), carrot, onion, satsuma-imo (sweet potato), satoimo (taro), jinenzyo (Japanese yam), daikon (Japanese radish), akakabu (red turnip), gobo (burdock root), renkon (lotus root), yacon, yuri-ne (lily bulb), kuwai (arrowhead), ginger, garlic, and turmeric; (d) a yeast- and/or lactic acid bacterium-fermented product of one or more kinds of flowers and/or leaf vegetables selected from the group consisting of cabbage, shiso (perilla), mulberry leaves, dokudami (Korean houttuynia), yomogi (wormwood), kumazasa (kuma bamboo grass), and dandelion; (e) a yeast- and/or lactic acid bacterium-fermented product of one or more kinds of seaweeds selected from the group consisting of kombu (sea tangle), wakame (Undaria pinnatifida), and mozuku (Nemacystus decipiens); (f) a yeast- and/or lactic acid bacterium-fermented product of one or more kinds of seeds selected from the group consisting of black sesame seeds, walnuts, and ginkgo nuts; and (g) a yeast- and/or lactic acid bacterium-fermented product of one or two kinds of mushrooms selected from the group consisting of maitake (Grifola frondosa) and shiitake (Lentinus edodes).

公开(公告)号：US09655913B2

公开(公告)日：2017-05-23

申请号：US15190367

申请日：2016-06-23

Applicant: Hong Kong Baptist University ,  Changshu HKBU Technology Company Limited

Inventor： Zhaoxiang Bian ,  Huaixue Mu ,  Chengyuan Lin ,  Jinjin Wang ,  Zhijun Yang ,  Aiping Lu ,  Albert Sun Chi Chan

IPC: A61K31/7048 ,  A61K36/888 ,  A61K31/09 ,  A61K31/341 ,  A61K31/34 ,  A61K9/00 ,  A61K31/353

CPC classification number: A61K31/7048 ,  A61K9/0019 ,  A61K9/0053 ,  A61K31/09 ,  A61K31/34 ,  A61K31/341 ,  A61K31/353 ,  A61K36/888

Abstract: The present invention relates to the bioactive components with the anti-proliferative property. In particular, the invention relates to one flavonol compound isolated from the root of Lasia spinosa Linn. Thwait or chemically synthesized and its specific anticancer/antitumor activity. This invention has a specific application in treating human esophageal cancer.

公开(公告)号：US20160184218A1

公开(公告)日：2016-06-30

申请号：US14975863

申请日：2015-12-21

Applicant: Kodimule Prasad

Inventor： Kodimule Prasad

IPC: A61K8/97 ,  A61Q19/02 ,  A61K36/888 ,  A61Q19/08

CPC classification number: A61K8/97 ,  A61K8/68 ,  A61K36/888 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08

Abstract: Compositions derived from an extract of Amorphophallus konjac and methods for their use in the treatment of skin conditions. The compositions of the invention find use in maintaining the health of the skin and treating a variety of skin conditions, including wrinkles and fine lines, loss of skin tone, and hyperpigmentation. Without being limited to any particular theory or mechanism, the compositions of the invention treat skin conditions through the inhibition of enzymes, including but not limited to, collagenase, elastase and tyrosinase.

Abstract translation: 衍生自魔芋提取物的组合物及其用于治疗皮肤病症的方法。 本发明的组合物用于维持皮肤的健康并且治疗各种皮肤状况，包括皱纹和细纹，失去肤色和色素沉着。 本发明的组合物不限于任何特定的理论或机制，通过抑制酶（包括但不限于胶原酶，弹性蛋白酶和酪氨酸酶）来治疗皮肤病症。

公开(公告)号：US20150374778A1

公开(公告)日：2015-12-31

申请号：US14846786

申请日：2015-09-06

Applicant: Mingchun Xiao

Inventor： Mingchun Xiao

IPC: A61K36/9068 ,  A61K36/8988 ,  A61K36/07 ,  A61K36/752 ,  A61K36/284 ,  A61K36/484 ,  A61K36/575 ,  A61K36/236 ,  A61K36/232 ,  A61K36/237 ,  A61K36/268 ,  A61K36/85 ,  A61K36/185 ,  A61K36/46 ,  A61K36/21 ,  A61K36/515 ,  A61K36/54 ,  A61K36/258 ,  A61K36/65 ,  A61K36/804 ,  A61K36/481 ,  A61K36/714 ,  A61K36/12 ,  A61K36/884 ,  A61K36/8945 ,  A61K36/882 ,  A61K36/9062 ,  A61K36/734 ,  A61K36/8888

CPC classification number: A61K36/9068 ,  A23F3/163 ,  A61K36/07 ,  A61K36/076 ,  A61K36/12 ,  A61K36/185 ,  A61K36/21 ,  A61K36/232 ,  A61K36/233 ,  A61K36/236 ,  A61K36/237 ,  A61K36/258 ,  A61K36/268 ,  A61K36/284 ,  A61K36/46 ,  A61K36/48 ,  A61K36/481 ,  A61K36/482 ,  A61K36/484 ,  A61K36/515 ,  A61K36/53 ,  A61K36/532 ,  A61K36/535 ,  A61K36/538 ,  A61K36/539 ,  A61K36/54 ,  A61K36/575 ,  A61K36/65 ,  A61K36/66 ,  A61K36/68 ,  A61K36/71 ,  A61K36/714 ,  A61K36/734 ,  A61K36/752 ,  A61K36/804 ,  A61K36/85 ,  A61K36/88 ,  A61K36/882 ,  A61K36/884 ,  A61K36/888 ,  A61K36/8884 ,  A61K36/8888 ,  A61K36/8905 ,  A61K36/8945 ,  A61K36/8988 ,  A61K36/8998 ,  A61K36/906 ,  A61K36/9062 ,  A61K36/9064 ,  A61K36/9066 ,  A61K2300/00

Abstract: A pharmaceutical composition for treating cancers and preparation method thereof. Said composition for treating cancers contains Chinese medicinal materials including Rhizoma Pinelliae, Rhizoma Arisaematis, Rhizoma Gastrodiae etc., and said preparation method is in accordance with a conventional Chinese medicinal preparation method, manufacturing said composition to form any one of the ordinary oral preparations.

Abstract translation: 一种治疗癌症的药物组合物及其制备方法。 所述治疗癌症的组合物含有中药材，包括苦参，苦参，天麻等，所述制备方法按照常规的中药制备方法，制备所述组合物以形成任何一种普通口服制剂。

公开(公告)号：US20150250886A1

公开(公告)日：2015-09-10

申请号：US14431882

申请日：2013-09-30

Applicant: PHARMASCIENCE INC.

Inventor： Krishna Hari Bhandari ,  Naresh Talwar

IPC: A61K47/26 ,  A61K31/485

CPC classification number: A61K47/26 ,  A61K9/205 ,  A61K31/135 ,  A61K31/137 ,  A61K31/4468 ,  A61K31/451 ,  A61K31/485 ,  A61K31/5513 ,  A61K36/888 ,  A61K2300/00

Abstract: A modified release orally administrable abuse-deterrent pharmaceutical composition comprising: a therapeutically effective amount of an active pharmaceutical ingredient and konjac glucomannan. The active pharmaceutical ingredient can be selected from a number of compounds but is generally aimed to be a compound which is subject to widespread abuse such as opioids.

Abstract translation: 一种经口头给药的经口服给药的滥用药物组合物，其包含：治疗有效量的活性药物成分和魔芋葡甘露聚糖。 活性药物成分可以选自多种化合物，但通常旨在成为广泛滥用的化合物，例如阿片样物质。

公开(公告)号：US20140023675A1

公开(公告)日：2014-01-23

申请号：US13977780

申请日：2012-01-03

Applicant: Bruno Lina ,  Olivier Ferraris ,  Ho Hong Hai Vo ,  Francois-Loic Cosset ,  Judit Szecsi ,  Alain Heyraud ,  Hugues Lortat-Jacob ,  Julia Bartoli ,  Rabia Sadir ,  Thierry Livache ,  Benoit Darblade ,  Stephane Havet ,  Silvére Bonnet

Inventor： Bruno Lina ,  Olivier Ferraris ,  Ho Hong Hai Vo ,  Francois-Loic Cosset ,  Judit Szecsi ,  Alain Heyraud ,  Hugues Lortat-Jacob ,  Julia Bartoli ,  Rabia Sadir ,  Thierry Livache ,  Benoit Darblade ,  Stephane Havet ,  Silvére Bonnet

IPC: A61K31/737

CPC classification number: A61K31/737 ,  A61K31/715 ,  A61K36/05 ,  A61K36/888

Abstract: The present invention relates to polysaccharides selected from sulphated arabinogalactans, apiogalacturonans and sulphated heteroglycans intended to be used as a drug for the preventive or curative treatment of an influenza virus, as well as to the pharmaceutical compositions including, in particular in combination with at least one pharmaceutically acceptable carrier: either an extract of Codium fragile, including sulphated arabinogalactans, or an extract of Zostera marina or Lemna minor, including apiogalacturonans, or an extract of Caulerpa racemosa, including sulphated heteroglycans.

Abstract translation: 本发明涉及旨在用作预防或治疗性流感病毒的药物的硫酸化阿拉伯半乳聚糖，阿片半乳糖聚糖和硫酸化异糖聚糖的多糖，以及该药物组合物，特别是与至少一种 药学上可接受的载体：脆弱的Codium的提取物，包括硫酸化的阿拉伯半乳聚糖，或Zostera marina或Lemna minor的提取物，包括半乳糖醛酸聚糖或包括硫酸化杂聚糖的Caulerpa racemosa的提取物。

公开(公告)号：US20120108556A1

公开(公告)日：2012-05-03

申请号：US13348425

申请日：2012-01-11

Applicant: Gene H. Zaid ,  Thomas W. Burgoyne ,  Beth Ann Wolf

Inventor： Gene H. Zaid ,  Thomas W. Burgoyne ,  Beth Ann Wolf

IPC: A61K31/56 ,  A61P35/00

CPC classification number: A61K31/575 ,  A61K31/11 ,  A61K31/202 ,  A61K36/888 ,  A61K2300/00

Abstract: Methods for the treatment of human cancers, daily dosage forms for cancer patients, and methods of formulating the dosage forms are provided wherein the daily dosage form contains from about 10-6,000 mg of each of β-sitosterol, isovanillin, and linolenic acid. Preferably, the dosage forms are formulated by first creating an aqueous decoction of Arum palaestinum Boiss, followed by fortification of the decoction with additional quantities of β-sitosterol, isovanillin, and linolenic acid.

Abstract translation: 提供了治疗人类癌症的方法，癌症患者的日剂量形式和配制剂型的方法，其中日剂量形式含有约10-6,000mg的β-谷甾醇，异喹啉腈和亚麻酸。 优选地，通过首先产生Arum palaestinum Boiss的水煎剂配制剂型，随后用附加量的β-谷甾醇，异喹啉腈和亚麻酸强化煎剂。