Abstract:
There is provided a method for treating diabetes, the method comprising administering to a subject in need thereof an effective amount of a tetraspanin-2 (TSPAN2) protein expression or activity inhibitor. Further, there is provided a method for screening a diabetes therapeutic agent, the method comprising: (a) bringing a test material into contact with a cell expressing TSPAN2 gene; (b) determining the expression level of the TSPAN2 gene in the cell of (a) and in a control cell which is not in contact with the test material; and (c) selecting, as a diabetes therapeutic agent candidate, the test material reducing the expression level of the TSPAN2 gene in comparison with the control cell.
Abstract:
The present invention provides a neutron generating device for generating a high neutron flux by forming plasma in the vicinity of a target and by accelerating electrons and charged particles in the plasma toward the target. Magnetic field is formed in the vicinity of the target and a microwave generator irradiates microwaves into the space where the magnetic field is generated to thereby generate plasma in the space. The accelerated electrons and charged particles collide with the target to generate neutron flux. Also, to prevent the target surface from being excessively heated, the plasma is generated in a pulsed mode and target voltage is applied in a pulsed mode. To secure a continuous process, the level of target bias voltage for the target is adjusted so that the target re-adsorbs elements when the elements adsorbed on the target are depleted.
Abstract:
Provided is a manufacturing method of uniformly spherical gold nanoparticles using a synthesis method for controlling a size and a shape by repeating an etching and growing.
Abstract:
A method for preparing hydrophobic gold nanoparticles includes adding 1,2-dichlorobenzene as a solvent to gold precursor and using oleylamine and oleic acid with volume ratio of 7.5:2.5 to 5:5 as surfactants. The size of the prepared gold nanoparticles can be controlled over a broad range and may be utilized in various fields such as bio-imaging, photonic crystallization, sensors, organic catalysts, surface enhanced raman spectrum, electronic devices, etc. Further, a method for colorimetric detection of a strong acid uses hydrophilic nanoparticles that are phase transited from the prepared hydrophobic gold nanoparticles. Up to 5 ppm of low content hydrochloric acid can be detected utilizing phase transited hydrophilic nanoparticles in the colorimetric detection method, and the gold nanoparticles that were used in the detection of strong acid can be reused without loss of activity through neutralization with bases.
Abstract:
The present invention provides a hybrid reforming system for producing syngas through a reforming reaction between carbon dioxide plasma and a hydrocarbon material, the system comprising: a carbon dioxide feeder (110) which feeds carbon dioxide; a hydrocarbon material feeder (120) which feeds the hydrocarbon material; a plasma reformer (200) which respectively receives carbon dioxide and the hydrocarbon material from the carbon dioxide feeder (110) and the hydrocarbon material feeder (120), and produces primary syngas through a reforming reaction while producing the carbon dioxide plasma using electromagnetic waves; a wet carbon-refining device (130) which is arranged at a gas exhaust end of the plasma reformer (200) and filters and refines carbon contained in the primary syngas; and a catalyst dry-reformer (140) which is arranged at a gas exhaust end of the wet carbon-refining device (130) and produces secondary syngas by making the refined syngas undergo a catalyst dry-reforming reaction.
Abstract:
A coaxial drive apparatus for multidirectional control, including: a housing; a stage pivotally installed in the housing, with the object laid on the stage; a rotary shaft connected to the stage and rotated to cause the stage to pivot; a rotation transmitting unit transmitting a rotating force of the rotary shaft to the stage; a sliding pipe coaxially fitted over the rotary shaft so as to be moved along a lengthwise direction of the rotary shaft or to be rotated on a central axis of the rotary shaft; a moving unit moving the object laid on the stage in the lengthwise direction of the rotary shaft according to a movement of the sliding pipe, and moving the object in a transverse direction of the rotary shaft according to a rotation of the sliding pipe; and a controller providing a driving force to the rotary shaft and to the sliding pipe.
Abstract:
A demodulation device according to the present invention includes a spin device configured to output an oscillation signal; a phase control unit configured to assign a predetermined phase locking characteristic to the spin device, thereby causing the oscillation signal to be tuned to a modulation signal that is input to the spin device; and a detector configured to demodulate the oscillation signal that is output by the spin device and tuned to the modulation signal, thereby restoring information carried on the oscillation signal.
Abstract:
Disclosed is an economic method for concentrating virus and detecting virus, such that virus in a sample solution having low virus concentration can be concentrated with high efficiency within a short time. Particularly, the method comprising the steps of: (A) adding Concanavalin A (Con A) to a sample solution containing a virus, and reacting the added Concanavalin A with the virus in the sample solution to form a virus-Concanavalin A conjugate; and (B) separating the virus-Concanavalin A conjugate from the sample solution.
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating diabetes or fatty liver, and more specifically relates to a pharmaceutical composition for preventing or treating diabetes or fatty liver containing a CYP4A (cytochrome P450A) inhibitor as an active ingredient. According to the present invention, the CYP4A inhibitor suppresses endoplasmic reticulum stress, reduces the blood insulin concentration and suppresses apoptosis of liver cells, and hence exhibits effects in preventing or treating diabetes or fatty liver.
Abstract:
Disclosed is a novel method for detecting interactions of biomolecules. More particularly, the disclosed method includes (a) preparing a cell comprising (i) a first construct comprising a bait, a first labeling material and a translocation module; and (ii) a second construct comprising a prey and a second labeling material; (b) detecting the distribution of the first construct and the second construct in the cell. the present invention provides a method capable of detecting bindings and interactions occurring in a living cell in real time, and a method for screening a material that alters the binding and the interaction. The method of the present invention overcomes the disadvantages including inaccuracy and complexity of existing biomaterial interaction detection techniques. By labeling both constructs to promote accuracy, the present invention provides a novel real-time, antibody-free analysis.