Invention Grant
US09295667B2 Pharmaceutical composition for preventing or treating diabetes or fatty liver containing a CYP4A inhibitor as an active ingredient
有权
用于预防或治疗含有CYP4A抑制剂作为活性成分的糖尿病或脂肪肝的药物组合物
- Patent Title: Pharmaceutical composition for preventing or treating diabetes or fatty liver containing a CYP4A inhibitor as an active ingredient
- Patent Title (中): 用于预防或治疗含有CYP4A抑制剂作为活性成分的糖尿病或脂肪肝的药物组合物
-
Application No.: US14178090Application Date: 2014-02-11
-
Publication No.: US09295667B2Publication Date: 2016-03-29
- Inventor: Gun-Hwa Kim , Soohyun Kim , Jong-Soon Choi , Seung Il Kim , Edmond Changkyun Park
- Applicant: Korea Basic Science Institute
- Applicant Address: KR Daejeon
- Assignee: Korea Basic Science Institute
- Current Assignee: Korea Basic Science Institute
- Current Assignee Address: KR Daejeon
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Kongsik Kim; Richard B. Emmons
- Priority: KR10-2011-0080208 20110811
- Main IPC: A61K31/41
- IPC: A61K31/41 ; A61K31/415 ; A61K31/20 ; A61K31/18 ; A61K31/15 ; A61K31/4192 ; A61K31/155 ; A61K31/201 ; A61K31/4174
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating diabetes or fatty liver, and more specifically relates to a pharmaceutical composition for preventing or treating diabetes or fatty liver containing a CYP4A (cytochrome P450A) inhibitor as an active ingredient. According to the present invention, the CYP4A inhibitor suppresses endoplasmic reticulum stress, reduces the blood insulin concentration and suppresses apoptosis of liver cells, and hence exhibits effects in preventing or treating diabetes or fatty liver.
Public/Granted literature
Information query
