公开(公告)号：US20170131306A1

公开(公告)日：2017-05-11

申请号：US15126789

申请日：2015-03-09

Applicant: Hitachi High-Technologies Corporation

Inventor： Shinji TARUMI ,  Sakuichiro ADACHI ,  Chie YABUTANI ,  Akihisa MAKINO

IPC: G01N35/00 ,  G01N33/86 ,  G01N21/27 ,  G01N21/51 ,  G01N21/59

CPC classification number: G01N35/00871 ,  G01N21/272 ,  G01N21/51 ,  G01N21/59 ,  G01N33/4905 ,  G01N33/86 ,  G01N2021/135 ,  G01N2021/513 ,  G01N2021/825 ,  G01N2201/12753 ,  G01N2201/12792 ,  G16H10/40 ,  G16H50/20

Abstract: An automatic analytical apparatus includes a reaction container for mixing a sample with a reagent to react the sample to the reagent, a measurement unit that irradiates a reaction solution in the reaction container with light and measures the intensity of transmitted light or scattered light, a control unit that processes time-series light intensity data obtained through the measurement in the measurement unit, a storage unit that stores one or more approximation functions each approximating to a time-series change in the light intensity data, and an output unit that outputs a processing result of the control unit. The control unit selects any one of the approximation functions stored in the storage unit, calculates an approximate curve indicating a time-series change in the light intensity data using the selected approximation function, calculates deviation feature information based on deviation information between the light intensity data and the approximate curve, and detects and classifies an abnormality included in the light intensity data using the deviation feature information.

公开(公告)号：US09285306B2

公开(公告)日：2016-03-15

申请号：US13882902

申请日：2011-10-28

Applicant: Calum John MacGregor ,  Desmond Robert Gibson

Inventor： Calum John MacGregor ,  Desmond Robert Gibson

IPC: G01N21/27 ,  G01N21/3504 ,  G01N33/00

CPC classification number: G01N21/27 ,  G01N21/274 ,  G01N21/3504 ,  G01N33/0006 ,  G01N2201/1211 ,  G01N2201/12723 ,  G01N2201/12753 ,  G01N2201/12792

Abstract: An optical absorption gas sensor has an LED light source and a photodiode light detector, a temperature measuring device for measuring the LED temperature and a temperature measuring device for measuring the photodiode temperature. The sensor is calibrated by measuring the response of photodiode current at zero analyte gas concentration and at a reference analyte gas concentration. From these measurement, calibration data taking into account the effect of photodiode temperature on the sensitivity of the photodiode and, independently, the effect of changes in the spectrum of light output by the LED on the light detected by the photodiode with LED temperature can be obtained. Calibration data is written to memory in the gas sensor and in operation of the gas sensor, the output is compensated for both LED and photodiode temperature. The LED and photodiode can therefore be relatively far apart and operate at significantly different temperatures allowing greater freedom of optical pathway design.

Abstract translation: 光吸收气体传感器具有LED光源和光电二极管光检测器，用于测量LED温度的温度测量装置和用于测量光电二极管温度的温度测量装置。 通过测量零分析气体浓度和参考分析物气体浓度下的光电二极管电流的响应来校准传感器。 从这些测量中，考虑到光电二极管温度对光敏二极管的影响的校准数据，并且独立地，可以获得LED输出的光谱的变化对由LED温度由光电二极管检测的光的影响 。 校准数据被写入气体传感器中的存储器，并且在气体传感器的操作中，输出被补偿LED和光电二极管的温度。 因此，LED和光电二极管可以相对较远并且在显着不同的温度下操作，从而允许更大的光路设计自由度。

公开(公告)号：US08010309B2

公开(公告)日：2011-08-30

申请号：US12914866

申请日：2010-10-28

Applicant: Alan P. Lundstedt ,  Allen L. Hall ,  Ching-Hui Tseng

Inventor： Alan P. Lundstedt ,  Allen L. Hall ,  Ching-Hui Tseng

IPC: G06F17/10

CPC classification number: G01N21/274 ,  G01N21/359 ,  G01N35/00712 ,  G01N35/00871 ,  G01N2035/00881 ,  G01N2201/12753 ,  G01N2201/12792

Abstract: A method of analysis, analysis system, program product, apparatus, and method of supplying analysis of value incorporating the use of at least one data acquisition device, a central processor, and a communication link that is connectable between the data acquisition device and the central processor. The central processor is loaded with multivariate calibration models developed for predicting values for various properties of interest, wherein the calibration models are capable of compensating for variations in an effectively comprehensive set of measurement conditions and secondary material characteristics. As so configured, the calibration models can compensate for instrument variance without instrument-specific calibration transfer. Measurement results generated by the central processor can be transmitted to an output device of a user interface.

Abstract translation: 一种分析，分析系统，程序产品，装置和提供分析价值的方法，该方法包括使用至少一个数据采集设备，中央处理器和通信链路，该数据采集设备和数据采集设备与中央 处理器。 中央处理器装载有用于预测感兴趣的各种性质的值的多变量校准模型，其中校准模型能够补偿有效全面的测量条件和次要材料特性的变化。 如此配置，校准模型可以补偿仪器差异，无需仪器特定的校准传输。 由中央处理器生成的测量结果可以被发送到用户界面的输出设备。

公开(公告)号：US07843556B2

公开(公告)日：2010-11-30

申请号：US11579427

申请日：2004-05-13

Applicant: Sergey Babichenko ,  Enn Erme ,  Tatjana Ivkina ,  Larisa Poryvkina ,  Vitaly Sominsky

Inventor： Sergey Babichenko ,  Enn Erme ,  Tatjana Ivkina ,  Larisa Poryvkina ,  Vitaly Sominsky

IPC: G01N21/00

CPC classification number: G01N21/645 ,  G01N21/274 ,  G01N2021/6417 ,  G01N2021/6463 ,  G01N2201/12792

Abstract: The present invention discloses a portable, reliable, automated and simple device using Spectral Fluorescence Signature technology (SFS) for fast and accurate drug detection, quantification and data storage. The present also discloses a method for using Spectral Fluorescence Signature technology (SFS) for fast and accurate drug detection, quantification and data storage. Such device and method needing not highly skilled personnel or specific background to run the tests.

Abstract translation: 本发明公开了一种使用光谱荧光特征技术（SFS）的便携式，可靠，自动和简单的装置，用于快速准确的药物检测，定量和数据存储。 本发明还公开了一种使用光谱荧光特征技术（SFS）进行快速准确的药物检测，定量和数据存储的方法。 这种设备和方法不需要高技能的人员或具体的背景来运行测试。

公开(公告)号：US07118713B2

公开(公告)日：2006-10-10

申请号：US10821441

申请日：2004-04-09

Applicant: David A. Brock ,  Donald R. Hesser ,  Gary H. Krauth ,  Jack L. Zuidema ,  David L. Boger ,  Kevin J. Sheldrake

Inventor： David A. Brock ,  Donald R. Hesser ,  Gary H. Krauth ,  Jack L. Zuidema ,  David L. Boger ,  Kevin J. Sheldrake

IPC: B01L9/00

CPC classification number: G01N21/8483 ,  B01L9/52 ,  B01L2300/0825 ,  G01J2003/2866 ,  G01N21/274 ,  G01N21/4738 ,  G01N21/78 ,  G01N2021/0325 ,  G01N2201/0245 ,  G01N2201/12792

Abstract: A tray assembly for use with an apparatus adapted to inspect a liquid sample, including a support tray insertable within an inspection location within the liquid sample inspection apparatus so that a light source of the apparatus illuminates a liquid sample carried on the support tray and a detector of the apparatus receives light from the liquid sample when the support tray is positioned at the inspection location, and an insert supported within the support tray and having a first surface adapted to receive a first type of liquid carrier and a second surface adapted to receive a second type of liquid carrier different from the first type of liquid carrier.

Abstract translation: 一种用于与适于检查液体样品的设备一起使用的托盘组件，包括可插入在液体样品检查设备内的检查位置内的支撑托盘，使得设备的光源照亮承载在支撑托盘上的液体样品和检测器 当所述支撑托盘位于所述检查位置时，所述设备从所述液体样品接收光，以及插入件，其被支撑在所述支撑托盘内并且具有适于接纳第一类型的液体载体的第一表面和适于接收 第二类液体载体不同于第一类液体载体。

公开(公告)号：US20050268690A1

公开(公告)日：2005-12-08

申请号：US10863810

申请日：2004-06-08

Applicant: Kurt Weckstrom ,  Heikki Haveri ,  Mika Hietala

Inventor： Kurt Weckstrom ,  Heikki Haveri ,  Mika Hietala

IPC: G01N21/27 ,  G01N21/35 ,  G01N21/61 ,  G01N7/00

CPC classification number: G01N21/3504 ,  G01N21/274 ,  G01N21/61 ,  G01N2201/023 ,  G01N2201/1211 ,  G01N2201/12792

Abstract: The invention concerns a gas analyzer comprising: a measuring volume (2), a radiation source (1) for providing a beam to pass said measuring volume; a heat sink (16) for said radiation source; at least one thermal detector (3) having a hot junction within a support structure and receiving the radiation and a cold junction for reference within the same support structure and protected from said radiation; at least one optical bandpass filter (9) between said hot junction and said radiation source; and a thermal mass (11), which is formed of a material having high thermal conductance. The thermal mass has a cavity with a bottom step (34) and a rim (32), and a first length therebetween. The support structure has a frontal edge (35) and a base plate lip (33), and a second length therebetween. There is a radial gap between the thermal mass and the support structure. Press means urge said support structure in the cavity, whereupon a more efficient thermal contact is either between said frontal edge and said bottom step, or between said base plate lip and said rim. A first thermal barrier (17) is between the heat sink and the thermal mass, and a second thermal barrier (22) surrounds the thermal mass. A shield (19) formed of a material having high thermal conductance covers said second thermal barrier and is in thermal contact with said heat sink.

Abstract translation: 本发明涉及一种气体分析仪，包括：测量体积（2），用于提供光束以通过所述测量体积的辐射源（1） 用于所述辐射源的散热器（16）; 至少一个热探测器（3），其在支撑结构内具有热接合部，并且在相同的支撑结构内接受辐射和冷接点供参考，并保护免受所述辐射; 在所述热接头和所述辐射源之间的至少一个光学带通滤波器（9）; 以及由具有高导热性的材料形成的热质（11）。 热质量具有具有底部台阶（34）和边缘（32）的空腔，并且其间具有第一长度。 支撑结构具有前边缘（35）和基板唇缘（33），并且其间具有第二长度。 在热质和支撑结构之间存在径向间隙。 压制装置促使空腔中的所述支撑结构，由此在所述正面边缘和所述底部台阶之间或所述基板唇缘和所述边缘之间更有效的热接触。 第一热障（17）在散热器和热质量之间，第二热障（22）围绕热质量。 由具有高导热性的材料形成的屏蔽（19）覆盖所述第二热障，并与所述散热器热接触。

公开(公告)号：US4577966A

公开(公告)日：1986-03-25

申请号：US578758

申请日：1984-02-09

Applicant: Yoshiro Fukasawa

Inventor： Yoshiro Fukasawa

IPC: G01J1/44 ,  G01J3/08 ,  G01J3/42

CPC classification number: G01J3/08 ,  G01J3/42 ,  G01J2001/4242 ,  G01N2201/12792

Abstract: A double-beam spectrophotometer for spectral analysis of a sample in the infrared region is provided in which to eliminate errors in measurement of the absorbance of the sample caused by undesired thermal radiation from the sample itself, first and second sectors are used for division and recombination of beam paths and coordinated such that a detector which receives a beam along the combined beam path produces output signals consisting of components having a frequency f associated with the cycle of operation of the sectors and components having a frequency 2f, those components having frequencies f and 2f are independently derived out of the detector output signals, and the ratio of the components is computed, thereby obtaining the ratio of intensity of sample beam to reference beam independent of the undesired thermal radiation.

Abstract translation: 提供了用于红外区域中的样品的光谱分析的双光束分光光度计，其中消除了由来自样品本身的不期望的热辐射引起的样品的吸光度的测量误差，第一和第二扇区用于分离和重组 并且被协调使得沿着组合光束路径接收光束的检测器产生由具有频率f的分量组成的输出信号，所述分量具有频率f，该频率f与扇区和具有频率2f的分量的操作周期相关联，那些分量具有频率f和 2f被独立地从检测器输出信号中导出，并且计算分量的比率，由此获得独立于不期望的热辐射的采样光束与参考光束的强度之比。

公开(公告)号：US12061149B2

公开(公告)日：2024-08-13

申请号：US17324423

申请日：2021-05-19

Applicant: YSI, INC.

Inventor： Kevin Flanagan

IPC: G01N21/64 ,  G01N21/47 ,  G01N21/53 ,  G01N21/82 ,  G01N33/08 ,  G01N33/18 ,  H04N25/46

CPC classification number: G01N21/6456 ,  G01N21/4785 ,  G01N21/532 ,  G01N21/64 ,  G01N21/82 ,  G01N33/08 ,  G01N33/18 ,  H04N25/46 ,  G01N2021/6473 ,  G01N2021/6491 ,  G01N2201/061 ,  G01N2201/0633 ,  G01N2201/0636 ,  G01N2201/126 ,  G01N2201/12761 ,  G01N2201/12792

Abstract: A swept frequency fluorometer having a signal processor or processing module configured to:
receive signaling containing information about reflected light off one or more fluorescence species-of-interest in a liquid sample that is swept with light having a variable frequency range, the information including a characteristic optical frequency corresponding to a fluorescence species-of-interest in the liquid, and a characteristic/lifetime optical frequency corresponding to a distinct fluorescence lifetime in which the fluorescence species-of-interest remains in an excited state; and
provide corresponding signaling containing information about an identity of the fluorescence species-of-interest detected and distinguished from overlapping fluorescence species in the liquid using the characteristic/lifetime optical frequency, based upon the signaling received.

公开(公告)号：US09983122B1

公开(公告)日：2018-05-29

申请号：US15667851

申请日：2017-08-03

Applicant: Sea-Bird Electronics, Inc.

Inventor： Ronnie Van Dommelen ,  Burkhard Plache ,  Keith Brown ,  Wesley D. Strubhar ,  Andrew H. Barnard ,  Scott Feener

IPC: G01J1/42 ,  G01N21/27 ,  G01N21/33 ,  G01N21/25 ,  G01J3/10

CPC classification number: G01N21/274 ,  G01J3/10 ,  G01N21/255 ,  G01N21/33 ,  G01N2201/0621 ,  G01N2201/12753 ,  G01N2201/12792

Abstract: Technology is provided for an aqueous solution constituent analyzer. The analyzer includes an ultraviolet light emitting diode (LED) with a current source providing variable current thereto. A spectrometer is positioned for receiving light from the LED transmitted through an aqueous solution. A controller receives radiant flux data for a plurality of wavelengths and determines, based on the radiant flux data, a usable number of the plurality of wavelengths that satisfies a relative uncertainty threshold. The controller can increase the current to the LED if the usable number of wavelengths is less than a minimum threshold and calculate a concentration of a constituent of interest in the solution. The controller can also determine a peak wavelength of the plurality of wavelengths having the greatest intensity value, and decrease the current level to the LED if the peak wavelength has an intensity value greater than a saturation value for the spectrometer.

公开(公告)号：US20160054316A1

公开(公告)日：2016-02-25

申请号：US14932769

申请日：2015-11-04

Applicant: Quidel Corporation

Inventor： Richard L. Egan ,  Michael Jon Hale ,  Jhobe Steadman

IPC: G01N33/543 ,  G01N33/558 ,  G01N33/569 ,  G01N21/64

CPC classification number: G01N33/54366 ,  B01L9/52 ,  B01L2300/0816 ,  B01L2300/0825 ,  G01N21/6428 ,  G01N21/6486 ,  G01N21/8483 ,  G01N33/53 ,  G01N33/558 ,  G01N33/56944 ,  G01N33/56983 ,  G01N2021/6439 ,  G01N2201/12707 ,  G01N2201/12792 ,  G01N2333/11 ,  G01N2469/10

Abstract: A system comprised of an apparatus and a test device is described. The test device and the apparatus are designed to interact to determine the presence or absence of an analyte of interest in a sample placed on the test device.