Creating training data variability in machine learning for object labelling from images

    公开(公告)号:US12005592B2

    公开(公告)日:2024-06-11

    申请号:US17603175

    申请日:2020-03-21

    摘要: It is described an image labeling system (100) comprising: a support (2) for an object (3) to be labeled; a digital camera (1) configured to capture a plurality of images of a scene including said object (3); a process and control apparatus (5) configured to receive said images and generate corresponding labeling data (21-24, L1-L4) associated to said object (3); a digital display (4) associated with said support (2) and connected to the process and control apparatus (5) to selectively display additional images (7-13) selected from the group comprising: first images (7-11) in the form of backgrounds for the plurality of images and introducing a degree of variability in the scene; second images (12) indicating position and/or orientation according to which place said object (3) by a user on the support (2); third images (13) to be captured by the digital camera (1) and provided to the process and control apparatus (5) to evaluate a position of the digital camera (1) with respect the digital display (4); fourth images to be captured by the digital camera (1) and provided to the process and control apparatus (5) to evaluate at least one of the following data of the object (3): position, orientation, 3D shape.

    Herpesvirus with modified glycoprotein D

    公开(公告)号:US11466056B2

    公开(公告)日:2022-10-11

    申请号:US16307719

    申请日:2017-06-08

    摘要: The present invention is directed to a recombinant herpesvirus comprising a heterologous peptide and optionally polypeptide ligand capable of binding to (a) target molecule(s) and fused to or inserted into glycoprotein D. The recombinant herpesvirus may additionally comprise modifications for detargeting the virus from the natural receptors of gD. This allows the herpesvirus to efficiently target a cell for therapeutic purposes and a cell for virus production. The present invention further comprises a pharmaceutical composition comprising the herpesvirus, the herpesvirus for use in the treatment of a tumor, infection, degenerative disorder or senescence-associated disease, a nucleic acid and a vector coding for the gD, a polypeptide comprising the gD, and a cell comprising the herpesvirus, nucleic acid, vector or polypeptide. Moreover, a method for infecting a cell with the herpesvirus or for producing the herpesvirus is disclosed.

    Herpesvirus with Modified Glycoprotein B
    10.
    发明申请

    公开(公告)号:US20190336551A1

    公开(公告)日:2019-11-07

    申请号:US16307683

    申请日:2017-06-08

    摘要: The present invention is directed to a recombinant herpesvirus comprising a heterologous polypeptide ligand capable of binding to a target molecule and fused to or inserted into glycoprotein B at specific sites. The herpesvirus may comprise more than one ligand, and the additional ligand(s) may be comprised by a modified glycoprotein D and/or modified glycoprotein H. This allows the herpesvirus to target a cell for therapeutic purposes, and a cell for virus production. The present invention further comprises a pharmaceutical composition comprising the herpesvirus, the herpesvirus for use in the treatment of a tumor, infection, degenerative disorder or senescence-associated disease, a nucleic acid and a vector coding for the gB, a polypeptide comprising the gB, and a cell comprising the herpesvirus, nucleic acid, vector or polypeptide. Moreover, a method for infecting a cell with the herpesvirus or for producing the herpesvirus is disclosed.