US08637758B2
Disclosed is a thermoelectric material which is represented by the following composition formula (1) or (2) and comprises as a major phase an MgAgAs type crystal structure: (Tia1Zrb1Hfc1)xNiySn100-x-y composition formula (1); (Lnd(Tia2Zrb2Hfc2)1-d)xNiySn100-x-y composition formula (2); (wherein a1, b1, c1, x and y satisfy the conditions of: 0
US08637750B2
The present invention provides an inbred corn line designated NPID3013, methods for producing a corn plant by crossing plants of the inbred line NPID3013 with plants of another corn plant. The invention further encompasses all parts of inbred corn line NPID3013, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line NPID3013, and plants produced according to these methods.
US08637749B2
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH357331. The invention thus relates to the plants, seeds and tissue cultures of the variety CH357331, and to methods for producing a corn plant produced by crossing a corn plant of variety CH357331 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH357331.
US08637740B2
The invention relates to improved Brassica species, including Brassica juncea, improved oil and meal from Brassica juncea, methods for generation of such improved Brassica species, and methods for selection of Brassica lines. Further embodiments relate to seeds of Brassica juncea comprising an endogenous oil having increased oleic acid content and decreased linolenic acid content relative to presently existing commercial cultivars of Brassica juncea, seeds of Brassica juncea having traits for increased oleic acid content and decreased linolenic acid content in seed oil stably incorporated therein, and one or more generations of progeny plants produced from said seeds.
US08637739B2
The invention provides novel polypeptides, and variants and fragments thereof, having pesticidal activity against nematodes. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, biopesticide compositions, expression cassettes, and transformed microorganisms and plants comprising a nucleic acid of the invention. These compositions find use in methods for controlling pests, especially plant parasitic nematodes.
US08637722B2
Ethylene is oligomerized with a catalyst in which nickel is supported on a support containing silica and alumina. The catalyst has little deterioration over long periods and affords oligomers with high productivity.The ethylene oligomerization catalyst includes a support and a nickel compound supported on the support, the support including silica and alumina, and the amount of nickel supported is in the range of 0.0001 to 1 wt % based on the weight of the support, and the molar ratio of silica to alumina in the support (SiO2/Al2O3) is in the range of 100 to 2000. In a process of the invention, ethylene is oligomerized with use of the catalyst.
US08637715B2
The present invention relates to a catalyst comprising platinum, tin and a secondary noble metal selected from the group consisting of rhodium, palladium, gold and iridium. The catalyst may be on a support. In some embodiments, the support may comprise calcium. The catalyst is used for converting acetic acid to ethanol.
US08637713B2
A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drug substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmetric catalytic reduction and transfer hydrogenation, thereby providing an improved route to forming drug substances such as rivastigimine and rivastigimine hydrogen tartrate.
US08637712B2
Precipitations of nitrohydroxyaromatic salts out of the nitrated crude products obtained in the nitration of aromatic compounds after alkaline scrubbing, for example mononitrotoluenes, are prevented by contacting the nitrated crude products with an acidic ion exchanger. The nitrated crude products are preferably selected from a feedstream to a distillation column, a bottoms circulation stream of a distillation column and a feedstream to a vaporizer.
US08637704B2
At least 70% by weight of Compound 1 is the single crystalline form, Form A, Form C, or Form D, of the compound. A pharmaceutical composition comprises a pharmaceutically acceptable carrier or diluent, and compound 1, wherein at least 70% by weight of the compound is the single crystalline form, Form A, Form C, or Form D, of the compound. A method of treating a subject with cancer comprises administering to the subject an effective amount of compound 1 or the pharmaceutical composition.
US08637693B2
Provided herein are methods for dehydrating single-walled metal oxide nanotubes by heating the SWNT under vacuum at 250-300° C.; methods of dehydroxylating SWNT, comprising heating the SWNT under vacuum at 300-340° C., and methods for maximizing the pore volume of a SWNT, comprising heating the SWNT at 300° C. under vacuum to partially dehydroxylate and dehydrate the SWNT; methods of modifying the inner surface of a single walled aluminosilicate nanotube (SWNT), comprising dehydration or dehydration and dehydroxylation, followed by reacting the SWNT with a derivative under anhydrous conditions to produce a SWNT that is derivatized on its inner surface. The invention also includes single-walled nanotubes produced by the methods of the invention.
US08637689B2
Provided herein are processes for preparing estolides and estolide base oils from fatty acid reactants utilizing catalysts. Further provided herein are processes for preparing carboxylic esters from at least one carboxylic acid reactant and at least one olefin.
US08637687B2
Provided are processes for making an amide of a carboxylic acid by reacting an amine of the formula (I) H—NR1R2 (I) wherein R1 and R2 are the same or different, R1 comprising a C1-C4-alkyl, and R2 comprising hydrogen or a C1-C4-alkyl, the amine having a lower boiling point than water, with a carboxylic acid with at least 3 carbon atoms per molecule, said carboxylic acid optionally comprising at least one alcoholic hydroxyl group per molecule, and selecting a molar ratio of amine to carboxylic acid in the range of from 1.5:1 to 1:1. The reaction step occurs under temperature and pressure conditions at which water and amine according to formula (I) are gaseous, and in a single reactor, the water formed together with any unreacted amine is distilled off, any unreacted amine is separated from the water and said the unreacted amine is reintroduced into the reaction mixture.
US08637686B2
Provided herein are novel alkynyl and azide containing amino acids; kits containing these amino acids; peptides containing these amino acids; peptide macrocycles whose secondary structures are stabilized with linkers containing triazoles synthesized by reacting the side chains of the alkynyl and azide containing amino acids; and methods of making and using the alkynyl and azide containing amino acids, kits, peptides, triazole containing linkers, and peptide macrocycles.
US08637682B2
The present invention relates to novel benzoyl derivatives of 3-aminocarbazole, to a pharmaceutical composition containing them, to a method for preparing them and to the use of such compounds for the production of a drug that is useful in the treatment or prevention of disturbances associated with the production of prostaglandin E2 (PGE2), for instance inflammatory processes, pain, fever, tumours, Alzheimer's disease and atherosclerosis.
US08637681B2
Provided are pyrrolyl substituted dihydroindol-2-one derivatives represented by formula (I), pharmaceutically acceptable salts or solvates of said derivatives, or solvates of said salts, which are effective tyrosine kinase inhibitors. Also provided are the preparation methods of the above compounds, pharmaceutical compositions containing these compounds, and the use of these compounds in manufacturing drugs useful for the treatment or adjunctive treatment of tumors medicated by tyrosine kinases or proliferation or migration of tumor cells driven by tyrosine kinases in mammals (including human).
US08637679B2
The present invention relates to two main components, mahanine and mahanimbine (dehydroxy-mahanine) from Murraya koenigii for the treatment of glioblastoma and cervical carcinoma. Mahanimbine exhibited anti-cancer activity against lymphoid leukemia, myeloid leukemia, glioma, cervical carcinoma, pancreatic, colon and lung cancers in nineteen cells of different genetic status. C-3 hydroxy and NH groups are responsible contributing groups for their cytotoxicity. Mahanine reduced the doses of cisplatin and paclitaxel in cervical cancer showing better efficacy and useful as an adjunct chemotherapeutic agent to reduce toxicity these two drugs. A new cheap process for this preparation was established. EtOAc extract containing alkaloids enriched with mahanimbine and mahanine, is active against glioma and cervical cancers. Mahanine is targeting the chaperone Hsp90 which led to the proteasome-dependent degradation of several Hsp90-client proteins in diverse carcinoma types, glioblastoma, cervical carcinoma and pancreatic adenocarcinoma irrespective of their tissue origins thereby killing the cancer cells.
US08637674B2
The present invention provides pyrazole derivative compounds and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of preventing and treating osteoporosis.
US08637670B2
The present invention provides the compounds of formula (I): The present invention relates to imidazo[4,5-c]quinoline derivatives of formula (I), process for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases mediated by phosphatidylinositol-3-kinase (PBK) and/or mammalian target of rapamycin (mTOR) and/or tumor necrosis factor-α (TNF-oc) and/or interleukin-6 (IL-6), particularly in the treatment of cancer and inflammation.
US08637668B2
Process for preparing a cyclic tertiary methylamine of the formula I where A is a C4-alkylene group, a C5-alkylene group or a —(CH2)2—B—(CH2)2— group, where B is oxygen (O) or an N—R1 radical and R1 is C1-C5-alkyl, aryl or C5-C7-cycloalkyl, wherein an amino alcohol II from the group consisting of 1,4-aminobutanol, 1,5-aminopentanol, aminodiglycol (ADG) or aminoethylethanolamine of the formula IIa where R1 is as defined above or is hydrogen (H), in which case R1═CH3 in the amine I, is reacted with methanol in a reactor at a temperature in the range from 150 to 270° C. in the liquid phase in the presence of a copper-comprising heterogeneous catalyst.
US08637661B2
A process is described for the preparation of water-soluble cellulose hydrolysis product. The process comprise admixing cellulose with an ionic liquid capable of solvating or dissolving at least some of the cellulose, said ionic liquid being a compound comprises solely of cations and anions and which exists in a liquid state at a temperature at or below 150° C., and in which the anions are selected from halide and cyanate; and treating the resulting solvate or solution with an acid in the presence of water, said acid having a pKa in water of less than 2 at 25° C.
US08637659B2
The present invention relates to a novel family of monosaccharide derivatives and disaccharide derivatives and to a method of preparation thereof. A mono- and disaccharide derivatives according to the invention comprises at least one fatty acid ester and may further comprise one or more anionic groups and are useful for, inter alia, medical, pharmaceutical, cosmetic and food applications.
US08637654B1
This invention relates to a ribonucleic acid (RNA) based assay system for body fluid identification, and in particular to a novel, multiplex, parallel assay system based on messenger RNA expressed in human tissue, and to a method for using the same.
US08637651B2
The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
US08637648B1
This invention relates generally to compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier.
US08637643B2
Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
US08637642B2
Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
US08637638B2
The present invention provides compositions for altering a B cell mediated pathology in a patient. The compositions may comprise at least one and/or two chimeric proteins. Each chimeric protein comprises at least a portion of either the VH or VL region of a immunoglobulin molecule from particular B cells from a patient having a B cell mediated pathology, and an immunoglobulin constant region. The genes encoding VH and/or VL regions and the genes encoding immunoglobulin constant regions are isolated and inserted in an expression vector. The chimeric proteins may be produced by introducing the expression vectors into insect cell lines. Proteins may be further purified and conjugated to a compound such as an immunogenic carrier.
US08637636B2
Methods, apparatus, systems, computer programs and computing devices related to biologically assembling and/or synthesizing peptides and/or proteins are disclosed.
US08637622B2
The invention relates to a copolymer including betaininc units and hydrophobic and/or amphiphile units. The invention also relates to a method for preparing a copolymer including betaininc units and hydrophobic and/or amphiphile units, by controlled micellar polymerisation. The invention further relates to the uses of the copolymer. The copolymer is particularly used for increasing the viscosity of saline aqueous compositions.
US08637616B2
The present invention provides polymerization processes utilizing an ansa-metallocene catalyst system for the production of olefin polymers. Polymers produced from the polymerization processes have properties that vary based upon the presence or the absence of hydrogen and/or comonomer in the polymerization process.
US08637608B2
Fluoropolymers containing one or more azide group wherein the azide group is not a sulfonyl-azide group and processes of preparing them.
US08637606B2
Tires and tread are made from resin formed from the polymerization of phenol, aromatic, and terpene and/or mono- and bi-cyclic mono- and bi-unsaturated hydrocarbons.
US08637605B1
A moisture curable composition that includes a silage functional polyolefin, a first thermoplastic polymer that includes a thermoplastic elastomer selected from the group consisting of block copolymer selected from the group consisting of styrene-ethylene-butylene-styrene block copolymer, styrene-ethylene-propylene-styrene block copolymer, and combinations thereof, the block copolymer including no greater than 30 mole % styrene, saturated ethylene alphaolefin copolymer, butyl rubber, and combinations thereof, and polybutene having a number average molecular weight less than 5000, the composition being clear and resistant to ultraviolet light.
US08637599B2
It is the purpose of the present invention to improve air permeation resistance, low heat build-up property and strength at break. The present invention provides a rubber composition for an inner liner including (B) specific mica, (C) carbon black and/or silica and (D) an alkylphenol-sulfur chloride condensate indicated by the formula (D1): (Wherein R1 to R3 are an alkyl group having 5 to 12 carbons; x and y are an integer of 2 to 4; and n is an integer of 0 to 10), based on (A) specific rubber component.
US08637590B2
A protective coating applied to the underwater portion of a marine vessel operable to inhibit the growth of marine foulants. The coating comprises a polymer, a marine biocide, a preservative, an antimicrobial agent, and optionally a coloring agent. In certain embodiments, the marine biocide, preservative, and optional antimicrobial agent are chemically bonded with the polymer thereby significantly reducing the ability of the biocide, preservative, and antimicrobial agent to leach from the coating into the surrounding environment.
US08637586B2
A coating composition includes a UV curable film forming resin; a thixotropic and/or pseudoplastic anti-settling agent selected from at least one of an amine salt of a synthetic wax, a microcrystalline cellulose compound (MCC), a urea urethane, or a urethane enzymatically modified starch; a mar/scratch resistant additive selected from at least one of a mineral abrasive, glass particles, and ceramic particles; and water.
US08637583B2
A process for the manufacture of a fiber or foil comprising at least one optionally functionalized polymer with a high Tg selected from the group consisting of poly(aryl ether sulfone) (PAES), poly(aryl ether ketone) (PAEK) and aromatic polyimide, comprising the steps of (aa) providing a solution comprising at least 45 wt. % of the polymer, and at least 20 wt. %, of at least one halogen-free organic solvent (S1) for the polymer, both wt % based upon the weight of the solution; (bb) pushing the solution through a nozzle; and (cc) introducing the solution into a coagulation bath comprising: (cc1) at least one liquid (L1) in which the polymer is insoluble, and optionally (cc2) at least one organic solvent (S2) for the polymer, identical to or different from the organic solvent (S1), to form a fiber or foil. A fiber or foil obtained by this process as well as to fibers or foils with specific porosity features and/or mechanical properties.
US08637576B2
Benzamide derivatives of formulae I and II, and pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof, and pharmaceutical compositions comprising the same, are described and have therapeutic utility, particularly in the treatment of diabetes, obesity, and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are defined as provided herein.
US08637573B2
The invention relates to a new prescription of NAC in the treatment of endometriosis and of indications associated with endometriosis, in a human or mammalian animal patient. In addition an effective dose regimen of NAC in the treatment of endometriosis is proposed. In one embodiment of the present invention the prescribed treatment regimen may be used e.g. in order to control the frequency and the intensity of pain symptoms (dysmenorrhea, dyspareunia and acyclic chronic pelvic pain), to reduce the size of endometriotic lesions eventually up to their disappearance, to reduce recurrences after surgery and/or to improve fertility. Side effects of this treatment are virtually absent and, in particular, this treatment does not hinder pregnancy.
US08637570B2
A pharmaceutical composition comprising a docusate; an osmotic laxative; and a benzoate.
US08637567B2
This invention provides compounds, compositions and methods for treating a cognitive disorder or memory disorder in animals that result from aging or other neurodegenerative condition. In particular, compounds of this invention can stimulate neural cell growth, increased amounts of cells containing a key enzyme needed for production of the cholinergic neurotransmitter, and can improve memory and cognitive function in animals who have experienced a loss of memory or cognitive function.
US08637559B2
The present invention provides a oxazole compound represented by Formula (1), or a salt thereof: wherein R1 is an aryl group which may have one or more substituents; R2 is an aryl group or a nitrogen atom-containing heterocyclic group each of which may have one or more substituents; and W is a divalent group represented by —Y1-A1- or —Y2—C(═O)— wherein Y1 is a group such as —C(═O)—, A1 is a group such as a lower alkylene group, and Y2 is a group such as a piperazinediyl group. The oxazole compound has a specific inhibitory action against phosphodiesterase 4.
US08637553B2
A compound of Formula (I): salts thereof, prodrugs thereof, metabolites thereof, pharmaceutical compositions containing such a compound, and use of such compound and compositions to treat diseases mediated by raf, VEGFR, PDGFR, p38 and flt-3.
US08637548B2
A compound of formula: where Ar1, Ar2, X, R3, and m are as disclosed herein or a pharmaceutically acceptable salt thereof (a “Cycloheteroalkenyl Compound”); compositions comprising an effective amount of a Cycloheteroalkenyl Compound; and methods for treating or preventing pain, UI, an ulcer, IBD, IBS, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia, or depression in an animal comprising administering to an animal in need thereof an effective amount of a Cycloheteroalkenyl Compound are disclosed herein.
US08637540B2
This invention relates to an abuse deterrent dosage form of opioid analgesics, wherein an analgesically effective amount of opioid analgesic is combined with a polymer to form a matrix.
US08637512B2
A sustained release formulation of lamotrigine or a pharmaceutically acceptable derivative thereof and methods of treatment and uses thereof.
US08637509B2
Herein are disclosed azaindazoles of formula (I) where the various groups are defined herein, and which are useful for treating cancer.
US08637506B2
The mechanism by which the high bone mass (HBM) mutation (G171V) of the Wnt coreceptor LRP5 regulates the canonical Wnt signaling was investigated. The mutation was previously shown to reduce Dkk protein-1-mediated antagonism, suggesting that the first YWTD repeat domain where G171 is located may be responsible for Dkk protein-mediated antagonism. However, we found that the third YWTD repeat, but not the first repeat domain, is required for DKK1-mediated antagonism. Instead, we found that the G171V mutation disrupted the interaction of LRP5 with Mesd, a chaperon protein for LRP5/6 that is required for the coreceptors' transport to cell surfaces, resulting in less LRP5 molecules on the cell surface. Although the reduction in the level of cell surface LRP5 molecules led to a reduction in Wnt signaling in a paracrine paradigm, the mutation did not appear to affect the activity of coexpressed Wnt in an autocrine paradigm. Together with the observation that osteoblast cells produce autocrine canonical Wnt, Wnt7b, and that osteocytes produce paracrine Dkk1, we believe that the G171V mutation may cause an increase in Wnt activity in osteoblasts by reducing the number of targets for paracrine Dkk1 to antagonize without affecting the activity of autocrine Wnt.
US08637503B2
Disclosed is the unexpected finding that enantiomers of phenothiazines, preferably the (+) enantiomer of promethazine, are particularly effective in inhibiting the bone resorbing cells, osteoclasts, thus providing new uses and methods for reducing bone loss and, e.g., treating periodontitis and osteoporosis. The invention provides a range of such uses, methods, medicaments and associated compositions and kits.
US08637502B2
The invention relates to Heterocyclic-Substituted Piperidine Compounds, compositions comprising an effective amount of a Heterocyclic-Substituted Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Heterocyclic-Substituted Piperidine Compound.
US08637487B2
Indigestible oligosaccharides having a molecular weight of 450 Da to 3700 Da are used for the improvement of insulin resistance, the prevention of post-prandial glycaemic dip, and/or the decrease of the post-prandial glucose response of a meal, which is consumed within 72 hours after the consumption of the first product. The oligo-saccharides are especially galacto-oligosaccharides, and are advantageously administered a few hours prior to having the meal.
US08637480B2
It is an object of the present invention to provide a novel mitochondrial function-improving agent and a novel PGC-1α expression inducing agent. The present invention provides a mitochondrial function-improving agent and a PGC-1α expression inducing agent each of which comprises a lysine-specific demethylase-1 (LSD-1) inhibitor.
US08637477B2
Methods and compositions are provided for delivery of therapeutic nucleic acids to a target cell. A chimeric antigen is provided to encapsulate, bind, or otherwise carry a nucleic acid molecule to a target cell where the chimeric antigen and nucleic acid are internalized by receptor-mediated endocytosis. The chimeric antigen has a nucleic acid interaction domain, a target binding domain, and an immune response domain that may include a target antigen. Targeting is generally provided by the specificity of the target binding domain for a particular target cell receptor, but may also be provided by inclusion of a targeting antigen within the immune response domain. The combined delivery of chimeric antigen and nucleic acid, which may be a siRNA, may be synergistic in certain applications, for example in breaking host tolerance to a virus or in providing immunostimulation.
US08637471B2
The outcome of an in vitro fertilization (IVF) of a woman in terms of chances of successful pregnancy or the fertility status of a woman is predicted based on nucleotide analysis of the histidine-rich glycoprotein (HRG) gene or protein analysis of HRG. The proline isoform of HRG or an amino acid fragment thereof can further be used to increases the success of pregnancy of a woman.
US08637470B2
Novel peptides referred to as small humanin-like peptides (SHLPs) are provided herein along with nucleic acids encoding SHLPs and probes that selectively bind SHLPs. SHLPs have wide-ranging activity, including neuroprotective activity, anticancer activity, and cell survival activity. Also provided herein are therapeutic methods comprising administering an effective amount of an SHLP to a subject in need of treatment.
US08637461B2
The method of diagnosing and treating oxidative stress-impaired wound healing allows a practitioner to identify a subject at risk of having impaired wound healing by identifying the sensitivity of that patient to IGF-1. A finding of IGF-1 resistance, either systemically or at the site of an already existing wound, indicates an increased likelihood that the wound will have difficulty healing. In addition, identifying IGF-1 resistance by this method indicates that treatment of a wound with a combination of an antioxidant, IGF-1 and IGFBP-1 will provide optimal healing.
US08637455B2
The presently disclosed subject matter relates to peptides having binding affinity for glycopeptide antibiotics and methods and compositions for delivering glycopeptide antibiotic to the surface of medical devices. The peptide compositions can comprise a peptide having binding affinity for a surface material of a medical device that is coupled to the peptide having binding affinity for glycopeptide antibiotic. Also provided are methods of applying the peptide compositions to a medical device by contacting the peptide compositions with a surface of the medical device. In addition, kits are provided comprising the peptide compositions.
US08637447B2
The present invention relates to viral capsid proteins, as a medicament for the treatment of a pathologic disorder. More particularly, the invention relates to the viral capsid proteins VP1, VP2 and VP3, preferably, the SV40 VP1 or any peptide, fragment, mutant, derivative and mixtures thereof or of virus-like particles (VLP's) comprising the same, as the active ingredient in compositions for the treatment of pathologic disorders, preferably disorders associated with inactivation of cellular proteins involved with quality control processes, particularly, chaperones. The invention further provides methods for the treatment of such disorders and the use of the SV40 capsid proteins for the preparation of pharmaceutical compositions.
US08637445B2
The invention provides a benefit agent delivery particle comprising hydroxylpropyl cellulose. The benefit agent delivery particle may further comprise a non-polysaccharide polymer, preferably an aminoplast polymer. The benefit agent delivery particle may comprise a perfume. The invention also provides a process for the manufacture of the particles in which perfume oil is encapsulated using emulsion polymerization to form core-shell particles, (in the alternative the perfume may be adsorbed later) and, a further polymer layer is formed on the outer surface of the core shell-particles in the presence of the delivery aid.
US08637444B2
A method of delivering a material to a person comprising applying an anhydrous composition to a person, wherein the anhydrous composition comprises a base and metal organic framework formed from a recyclable porous material with the material adsorbed into the metal organic framework, and the recyclable porous material has a structure that breaks down when contacted with water to release the material. An anhydrous composition comprising a base and a metal organic framework formed from a recyclable porous material with the material adsorbed into the metal organic framework, wherein the recyclable porous material has a structure that breaks down when contacted with water to release the material.
US08637439B2
Compositions adapted for use as a bathing (shower or bath) gel for personal cleansing are provided, the compositions containing reduced loadings of relatively harsh anionic surfactants and of fragrance oils, but retaining a spectrum of functional properties perceived by consumers as desirable. The compositions include lower concentrations of anionic surfactants compared to standard bathing gel compositions, but the addition of quantities of a long-chain alkyl, hydroxyalkyl cellulose derivative to the composition preserves or enhances functional properties such as viscosity, skin mildness, foam generation on lathering, subjective perceived cleansing appreciation, and fragrance performance. The bathing gels provide an environmental benefit such as reduced surfactant loading, biodegradability, and aquatic toxicity of wastewater streams when used in the place of standard bathing gels.
US08637438B2
A lubricating oil composition for internal combustion engines comprising a base oil containing at least one component selected from an α-olefin oligomer having 16 to 40 carbon atoms obtained by oligomerizing α-olefin(s) having 2 to 20 carbon atoms using a metallocene catalyst, and the hydrogenated derivative thereof; an α-olefin oligomer having 16 to 40 carbon atoms derived from an α-olefin dimer obtained using a metallocene catalyst, and the hydrogenated derivative thereof; and the like. The lubricating oil composition has an excellent low-temperature fluidity, a low evaporativity, and a good oxidation stability.
US08637432B2
Alkyl ether sulfates having 1 to 9 carbon atoms in the alkyl chain and 1 to 20 alkyleneoxy units in the ether moiety are suitable for use as low-foam additives for enhancing the activity of water-soluble or partially water-soluble agrochemicals. They can be used to produce low-foam preparations for crop protection.
US08637423B2
This invention relates to a catalyst and method for hydrodesulfurizing naphtha. More particularly, a Co/Mo metal hydrogenation component is loaded on a high temperature alumina support in the presence of a dispersion aid to produce a catalyst that is then used for hydrodesulrurizing naphtha. The high temperature alumina support has a defined surface area that minimizes olefin saturation.
US08637421B2
The present invention discloses a catalyst system based on a metallocene catalyst component and a new single site catalyst component for the production in a single reactor of improved polyolefins having a bimodal molecular weight distribution.
US08637412B2
A first PECVD process incorporating a silicon oxide precursor alone and then with an organo-silicon precursor with increasing flow while the flow of the silicon oxide precursor is reduced to zero provides a graded carbon adhesion layer whereby the content of C increases with layer thickness and a second PECVD process incorporating an organo-silicon precursor including an organic porogen provides a multiphase ultra-low k dielectric. The multiphase ultra-low k PECVD process uses high frequency radio frequency power just above plasma initiation in a PECVD chamber. An energy post treatment is also provided. A porous SiCOH dielectric material having a k less than 2.7 and a modulus of elasticity greater than 7 GPa is formed.
US08637411B2
Methods of depositing a film on a substrate surface include surface mediated reactions in which a film is grown over one or more cycles of reactant adsorption and reaction. In one aspect, the method is characterized by intermittent delivery of dopant species to the film between the cycles of adsorption and reaction.
US08637408B2
Apparatus and methods are provided for efficiently reclaiming solvents used to clean surfaces of semiconductor wafers, etc. More particularly, embodiments of the present invention provide an in-situ reclaim approach that utilizes condensing mechanisms to reclaim evaporated solvent components. In these embodiments, the condensing can occur within a proximity head itself and/or along a vacuum line running from the proximity head to a vacuum tank. Other embodiments of the present invention provide an in-situ reclaim approach that prevents the evaporation of solvents at the onset by maintaining appropriate equilibrium gas phase concentrations between the liquid chemistries and gases used to process wafer surfaces.
US08637406B1
At least one mask layer formed over a substrate includes at least one of a dielectric material and a metallic material. By forming a first pattern in one of the at least one mask layer, a patterned mask layer including said first pattern is formed. An overlying structure including a second pattern that includes at least one blocking area is formed over said patterned mask layer. Portions of said patterned mask layer that do not underlie said blocking area are removed. The remaining portions of the patterned mask layer include a composite pattern that is an intersection of the first pattern and the second pattern. The patterned mask layer includes a dielectric material or a metallic material, and thus, enables high fidelity pattern transfer into an underlying material layer.
US08637405B2
A method of texturing a surface of a crystalline silicon substrate is provided. The method includes immersing a crystalline silicon substrate into an aqueous alkaline etchant solution to form a pyramid shaped textured surface, with (111) faces exposed, on the crystalline silicon substrate. The aqueous alkaline etchant solution employed in the method of the present disclosure includes an alkaline component and a nanoparticle slurry component. Specifically, the aqueous alkaline etchant solution of the present disclosure includes 0.5 weight percent to 5 weight percent of an alkaline component and from 0.1 weight percent to 5 weight percent of a nanoparticle slurry on a dry basis.
US08637401B1
A method is explained that allows for a via to be filled with a dispensed material while the substrate is in continuous movement. A device is described that allows for a via to be filled while the target substrate is in continuous movement. The device consists of a material jetting system, a machine vision system that can detect the optimum trigger point, an electronic control circuit, a feedback mechanism and a web handling provision.
US08637400B2
A method of forming a semiconductor structure includes forming a sacrificial conductive material layer. The method also includes forming a trench in the sacrificial conductive material layer. The method further includes forming a conductive feature in the trench. The method additionally includes removing the sacrificial conductive material layer selective to the conductive feature. The method also includes forming an insulating layer around the conductive feature to embed the conductive feature in the insulating layer.
US08637395B2
A single damascene or dual damascene interconnect structure fabricated with a photo-patternable low-k dielectric (PPLK) which is cured after etching. This method prevents the PPLK damage and the tapering of the edges of the interconnect structure. In one embodiment, the method of the present invention includes depositing a photo-patternable low-k (PPLK) material atop a substrate. The at least one PPLK material is patterned, creating a single damascene structure. For dual damascene structures, a second PPLK layer is coated and patterned. An etch process is performed to transfer the pattern from the PPLK material into at least a portion of the substrate. A diffusion liner and a conductive material can be deposited after the etch process. The resulting structure is cured anytime after etching in order to transform the resist like PPLK into a permanent low-k material that remains within the structure.
US08637390B2
Metal gate structures and methods for forming thereof are provided herein. In some embodiments, a method for forming a metal gate structure on a substrate having a feature formed in a high k dielectric layer may include depositing a first layer within the feature atop the dielectric layer; depositing a second layer comprising cobalt or nickel within the feature atop the first layer; and depositing a third layer comprising a metal within the feature atop the second layer to fill the feature, wherein at least one of the first or second layers forms a wetting layer to form a nucleation layer for a subsequently deposited layer, wherein one of the first, second, or third layers forms a work function layer, and wherein the third layer forms a gate electrode.
US08637388B2
A heat generating component of a semiconductor device is located between two heavily doped semiconductor regions in a semiconductor substrate. The heat generating component may be a middle portion of a diode having a light doping, a lightly doped p-n junction between a cathode and anode of a silicon controlled rectifier, or a resistive portion of a doped semiconductor resistor. At least one thermally conductive via comprising a metal or a non-metallic conductive material is place directly on the heat generating component. Alternatively, a thin dielectric layer may be formed between the heat generating component and the at least one thermally conductive via. The at least one thermally conductive via may, or may not, be connected to a back-end-of-line metal wire, which may be connected to higher level of metal wiring or to a handle substrate through a buried insulator layer.
US08637386B2
An electronic device includes a silicon carbide layer having a first conductivity type and a main junction adjacent a surface of the silicon carbide layer, and a junction termination region at the surface of the silicon carbide layer adjacent the main junction. Charge in the junction termination region decreases with lateral distance from the main junction, and a maximum charge in the junction termination region may be less than about 2×1014 cm−2.
US08637369B2
An embodiment of a method for manufacturing a power device with conductive gate structures inside etched trenches. Such trenches include sidewalls and a bottom, wherein covering the sidewalls and the bottom of the trench is a first insulating coating layer. In the formation of the conductive gate structure, openings within the first material in the trench are made such that a conductive central region of a second conductive material having a different resistivity than the first conductive material are able to be electrically coupled together through a plurality of conductive bridges between said second conductive coating layer and said conductive central region.
US08637368B2
Fabricating a semiconductor device includes: forming a gate trench in an epitaxial layer overlaying a semiconductor substrate; disposing gate material in the gate trench; forming a body in the epitaxial layer; forming a source in the body; forming an active region contact trench that has a varying trench depth; and disposing a contact electrode within the active region contact trench. Forming the active region contact trench includes performing a first etch to form a first contact trench depth associated with a first region, and performing a second etch to form a second contact trench depth associated with a second region. The first contact trench depth is substantially different from the second contact trench depth.
US08637367B2
Method for producing an insulation layer between a first electrode and a second electrode in a trench of a semiconductor body, wherein the method comprises the following features: providing a semiconductor body with a trench formed therein, wherein a first electrode is formed in a lower part of the trench, producing an insulation layer on the first electrode and at the sidewalls of the trench in an upper part of the trench in such a way that the insulation layer is formed in a U-shaped fashion in the trench, producing a protective layer on the insulation layer at least at the bottom of the remaining void in the trench, removing the insulation layer at the sidewalls of the trench in the upper part of the trench, removing the protective layer, producing a second electrode at least on the insulation layer above the first electrode.
US08637366B2
A memory cell according to the present invention comprises a bottom conductor, a doped semiconductor pillar, and a top conductor. The memory cell does not include a dielectric rupture antifuse separating the doped semiconductor pillar from either conductor, or within the semiconductor pillar. The memory cell is formed in a high-impedance state, in which little or no current flows between the conductors on application of a read voltage. Application of a programming voltage programs the cell, converting the memory cell from its initial high-impedance state to a low-impedance state. A monolithic three dimensional memory array of such cells can be formed, comprising multiple memory levels, the levels monolithically formed above one another.
US08637362B2
A memory array with data/bit lines extending generally in a first direction formed in an upper surface of a substrate and access transistors extending generally upward and aligned generally atop a corresponding data/bit line. The access transistors have a pillar extending generally upward with a source region formed so as to be in electrical communication with the corresponding data/bit line and a drain region formed generally at an upper portion of the pillar and a surround gate structure substantially completely encompassing the pillar in lateral directions and extending substantially the entire vertical extent of the pillar and word lines extending generally in a second direction and in electrical contact with a corresponding surround gate structure at at least a first surface thereof such that bias voltage applied to a given word line is communicated substantially uniformly in a laterally symmetric extent about the corresponding pillar via the surround gate structure.
US08637356B2
A non-volatile bistable nano-electromechanical switch is provided for use in memory devices and microprocessors. The switch employs carbon nanotubes as the actuation element. A method has been developed for fabricating nanoswitches having one single-walled carbon nanotube as the actuator. The actuation of two different states can be achieved using the same low voltage for each state.
US08637354B2
When a transistor including a conductive layer having a three-layer structure is manufactured, three-stage etching is performed. In the first etching process, an etching method in which the etching rates for the second film and the third film are high is employed, and the first etching process is performed until the first film is at least exposed. In the second etching process, an etching method in which the etching rate for the first film is higher than that in the first etching process and the etching rate for a “layer provided below and in contact with the first film” is lower than that in the first etching process is employed. In the third etching process, an etching method in which the etching rates for the first to the third films are higher than those in the second etching process is preferably employed.
US08637351B2
The invention relates in a general aspect to a method of making vertically protruding elements on a substrate, said elements having a tip comprising at least one inclined surface and an elongated body portion extending between said substrate and said tip. The method comprises an anisotropic, crystal plane dependent etch forming said inclined surface(s); and an anisotropic, non crystal plane dependent etch forming said elongated body portion; combined with suitable patterning processes defining said protruding elements to have a predetermined base geometry.
US08637350B2
A method of manufacturing a chip-stacked semiconductor package, the method including preparing a base wafer including a plurality of first chips each having a through-silicon via (TSV); bonding the base wafer including the plurality of first chips to a supporting carrier; preparing a plurality of second chips; forming stacked chips by bonding the plurality of second chips to the plurality of first chips; sealing the stacked chips with a sealing portion; and separating the stacked chips from each other.
US08637348B2
An insulating layer which releases a large amount of oxygen is used as an insulating layer in contact with a channel region of an oxide semiconductor layer, and an insulating layer which releases a small amount of oxygen is used as an insulating layer in contact with a source region and a drain region of the oxide semiconductor layer. By releasing oxygen from the insulating layer which releases a large amount of oxygen, oxygen deficiency in the channel region and an interface state density between the insulating layer and the channel region can be reduced, so that a highly reliable semiconductor device having small variation in electrical characteristics can be manufactured. The source region and the drain region are provided in contact with the insulating layer which releases a small amount of oxygen, thereby suppressing the increase of the resistance of the source region and the drain region.
US08637336B2
A method of producing a semiconductor wafer, which includes: placing a wafer (10) provided with a substrate (11) and a semiconductor layer (20) formed thereon, on a carrier plate (fixing plate) (31) of a grinder via fixing wax (33a and 33b) such that the surface (10a) to be ground faces upward; heating the carrier plate to soften the fixing wax; pressure-contacting the wafer from the side of the surface (10a) to be ground using an air bag such that a portion of the softened fixing wax spreads and protrudes from the peripheral edge of the wafer; cooling the carrier plate while applying pressure to cure the fixing wax and fix the wafer onto the carrier plate; and rotating the surface (10a) to be ground of the fixed wafer while pressure-contacting the surface (10a) to the grinding plate of the grinder, thereby grinding the surface (10a) to be ground.
US08637328B2
An integrated circuit and method for making an integrated circuit including doping a semiconductor body is disclosed. One embodiment provides defect-correlated donors and/or acceptors. The defects required for this are produced by electron irradiation of the semiconductor body. Form defect-correlated donors and/or acceptors with elements or element compounds are introduced into the semiconductor body.
US08637319B2
A method for detecting human or animal blood traces on a surface is described. The method is fundamentally based on the reaction of luminol and includes the preliminary operation of atomizing an inorganic powder suspension, such as titania, silica, alumina, hydroxyapatite, or the like, onto the surface to be investigated, after which a composition of luminol, a peroxidic oxidizing agent and an alkaline agent in an amount providing a pH within the range of 10 to 14, is atomized on the surface. A kit for carrying out the detection method of the invention is also described.
US08637315B2
Processes vectors and engineered cell lines for large-scale transfection and protein production in mammalian cells, especially Chinese Hamster Ovary (CHO) cells are described in which transfection efficiencies are realized through the use of a single vector system, the use of functional oriP sequences in all plasmids, the use of codon-optimized Epstein-Barr virus nuclear antigen-1 (EBNA1) constructs the use of a fusion protein between a truncated Epstein-Barr virus nuclear antigenen-1c (EBNA1c) protein and a herpes simplex virus protein VP16, the use of a 40 kDa fully deacetylated poly(ethylenimine) as a transfection reagent, the use of co-expression of a fibroblast growth factor (FGF) and/or the use of protein kinase B to potentiate heterologous gene expression enhancement by valproic acid (VPA).
US08637310B2
Disclosed herein is the finding that treatment with a ROCK inhibitor increases proliferation and induces immortalization of primary keratinocytes. Accordingly, provided is a method of immortalizing primary keratinocytes by exposure to a ROCK inhibitor. Also provided are immortalized primary keratinocytes produced by the described method, as well as organotypic tissue equivalents and cell cultures comprising the immortalized primary keratinocytes. Furthermore, ROCK inhibitor-treated cells show a greatly increased ability to support viral DNA replication of both “low risk” and “high risk” HPV genomes, indicating that ROCK inhibitors will be useful for studying the life cycles of a wide range of HPVs.
US08637308B2
The present invention provides a method for activating a Natural Killer (NK) cell by contacting the NK cell in vitro with an activating tumor cell preparation (ATCP). The invention also provides an activated NK cell produced by such a method and its use in the treatment of cancer.
US08637305B2
The invention disclosed herein is directed to methods of identifying a polypeptide suitable for epitope liberation including, for example, the steps of identifying an epitope of interest; providing a substrate polypeptide sequence including the epitope, wherein the substrate polypeptide permits processing by a proteasome; contacting the substrate polypeptide with a composition including the proteasome, under conditions that support processing of the substrate polypeptide by the proteasome; and assaying for liberation of the epitope. The invention further relates to vectors including a housekeeping epitope expression cassette. The housekeeping epitope(s) can be derived from a target-associated antigen, and the housekeeping epitope can be liberatable, that is capable of liberation, from a translation product of the cassette by immunoproteasome processing. The invention also relates to a method of activating a T cell comprising contacting a substrate polypeptide with an APC and contacting the APC with a T cell.
US08637290B2
The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, phosphatidic acid phosphatases (PAP) and/or lipid acyl hydrolase (LAH) activity, nucleic acids encoding them and antibodies that bind to them. Industrial methods, e.g., oil degumming, and products comprising use of these phospholipases are also provided.
US08637286B2
A non-naturally occurring microbial organism includes a microbial organism having a reductive TCA or Wood-Ljungdahl pathway in which at least one exogenous nucleic acid encoding these pathway enzymes is expressed in a sufficient amount to enhance carbon flux through acetyl-CoA. A method for enhancing carbon flux through acetyl-CoA includes culturing theses non-naturally occurring microbial organisms under conditions and for a sufficient period of time to produce a product having acetyl-CoA as a building block. Another non-naturally occurring microbial organism includes at least one exogenous nucleic acid encoding an enzyme expressed in a sufficient amount to enhance the availability of reducing equivalents in the presence of carbon monoxide or hydrogen, thereby increasing the yield of redox-limited products via carbohydrate-based carbon feedstock. A method for enhancing the availability of reducing equivalents in the presence of carbon monoxide or hydrogen includes culturing this organism for a sufficient period of time to produce a product.
US08637279B2
Disclosed herein is a recombinant Escherichia coli (E. coli) capable of producing D-xylonic acid from D-xylose and a method for producing D-xylonic acid using the same. The recombinant E. coli producing D-xylonic acid from D-xylose according to the present invention is a recombinant E. coli EWX4 (Microorganism deposition number KCTC11988BP) capable of producing D-xylonic acid from D-xylose. When utilizing the recombinant E. coli prepared by the method of the present invention, it is possible to produce D-xylonic acid from D-xylose with high yield while reducing production cost using sole carbon source.
US08637275B2
A new method of diagnosing postprandial hyperglycemia by indirectly measuring a blood glucose level is provided. Postprandial hyperglycemia is detected by measuring a glycation degree of lysine in hemoglobin, in which a side chain amino group of lysine is glycated (GHbLys %). Measurement of GHbLys % can be performed by cleaving hemoglobin by protease, treating a glycated part of a lysine residue in the obtained cleavage product of hemoglobin with fructosyl amino acid oxidase, and measuring a redox reaction between the glycated part and fructosyl amino acid oxidase.
US08637274B2
It is intended to provide an inhibitor for the formation of a γ-secretase complex which comprises a cholesterol synthesis inhibitor or a protein geranylgeranylation regulator as the active ingredient; and use of a cholesterol synthesis inhibitor or a protein geranylgeranylation regulator for producing the same. It is also intended to provide a method of screening a substance having an effect of inhibiting the formation of an active complex of γ-secretase which comprises assaying the activity of inhibiting cholesterol synthesis or quantifying cholesterol accumulated in lipid rafts in cells. It is also intended to provide a method of screening a cholesterol synthesis inhibitor, a protein geranylgeranylation regulator or an HMG-CoA reductase inhibitor which comprises assaying the effect of inhibiting the formation of an active complex of γ-secretase. Moreover, it is intended to provide a method of screening an effect of a test substance on γ-secretase which comprises measuring the distribution of constituents (niscastrin, APH-1, Pen-2 and so on) required by γ-secretase for the formation of its active complex in cells.
US08637273B2
The present invention provides antagonizing antibodies that bind to interleukin-7 receptor (IL-7R). The invention further provides a method of obtaining such antibodies and antibody-encoding nucleic acids. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof for the treatment and/or prevention of type 2 diabetes and immunological disorders, including type 1 diabetes, multiple sclerosis, rheumatoid arthritis, graft-versus-host disease, and lupus.
US08637272B2
The present invention provides an industrially useful improved halohydrin epoxidase, a method for producing the same, and a method for producing an epihalohydrin or 4-halo-3-hydroxybutyronitrile using the same. The improved halohydrin epoxidase of the present invention consists of an amino acid sequence in which a specific amino acid substitution mutation is introduced into an amino acid sequence of a wild-type halohydrin epoxidase comprising predetermined amino acid sequences I and II.
US08637271B2
Polymeric indicators are provided for visually monitoring, detecting, and/or determining the presence of metabolic byproducts from harmful or potentially harmful microorganisms.
US08637269B2
Melamine is a common industrial chemical contaminant which should be absent from food and feed supplies due to melamine's toxicity. Provided is a method to assess the presence of melamine in samples prepared from compositions. The method may include using a microbial enzyme called melamine deaminase which hydrolyzes melamine to ammeline and ammonia. The method may include assessing the presence of any ammonia produced from an enzymatic reaction between the sample and the enzyme.
US08637266B2
Methods for identifying compounds useful for treating diseases and conditions of the oral cavity are described herein.
US08637262B2
Provided are purified and isolated VEGF-C polypeptides capable of binding to at least one of KDR receptor tyrosine kinase (VEGFR-2) and Flt4 receptor tyrosine kinase (VEGFR-3); analogs of such peptides that have VEGF-C-like or VEGF-like biological activities or that are VEGF or VEGF-C inhibitors; polynucleotides encoding the polypeptides; vectors and host cells that embody the polynucleotides; pharmaceutical compositions and diagnostic reagents comprising the polypeptides; and methods of making and using the polypeptides. Methods of inhibiting endothelial cell proliferation are also provided.
US08637258B2
The present invention relates to a method of producing an antibody that cross-reacts with multiple KIR2DL polypeptides and neutralizes the inhibitory activity of such polypeptides.
US08637255B2
The nucleic acid sequences of adeno-associated virus (AAV) serotype 1 are provided, as are vectors and host cells containing these sequences and functional fragments thereof. Also provided are methods of delivering genes via AAV-1 derived vectors.
US08637248B2
In amplifying a region containing two allelic genes, the polymorphism of one of the allelic genes is positioned at or near the 3′ end of an amplification primer, so that the chain would extend only from one of the two primers, one that matches the mutant type nucleotide(s) and one that matches the wild-type nucleotide(s). The other primer is unaffected by the allelic genes but is positioned to include the other allelic gene in the amplicon. The PCR amplifies only the target genomic DNA having one specific allele of the first allelic gene. The technique exploits the fact that the haplotype of the first and the second allelic genes can be determined if the allele of the second allelic gene in the amplicon can be identified. Designing probes with complementary sequences for identifying the two alleles (major and minor) of the second allelic gene, and fixing the probe set on a solid support and hybridizing them with the amplicon to identify the probe that forms a hybrid, are characteristic features of the present invention.
US08637242B2
Provided are methods and apparatuses for performing sequencing using droplet manipulation, for example, via electrowetting-based techniques. Also provided are integrated methods and apparatuses for performing sample preparation and sequencing on the same apparatus. In addition, provided are methods of reducing reagent waste and preloaded consumable cartridges comprising reagents for sample preparation and/or sequencing.
US08637232B2
The present invention pertains to the monitoring and treatment of lung transplant recipients. In particular, the invention pertains to the use of biomarkers to predict or detect post-lung transplantation complications (e.g., organ rejection, acute organ rejection, organ injury, bronchiolitis obliterans, bronchiolitis obliterans syndrome, organizing pneumonia), fibroproliferative repair responses, interstitial lung diseases (e.g., idiopathic pulmonary fibrosis and other fibrotic lung diseases), and other immune-mediated lung diseases (e.g., graft versus host disease, scleroderma).
US08637228B1
A color photographic element has a reflective support and a blue light sensitive color record, a green light sensitive color record, and a red light sensitive color record and can be used to provide color photographic prints. The element also has a non-light sensitive layer over the red light sensitive color record. This non-light sensitive layer has (1) a hydrophilic colloid in an amount of at least 200 mg/m2 to and including 2,000 mg/m2, (2) matte particles, and (3) an acrylate latex polymer having latex particles having an average size of less than 1 μm and a glass transition temperature of at least 70° C. The dry weight ratio of the acrylate latex polymer to the hydrophilic colloid is at least 0.8:1 and the dry weight ratio of the acrylate latex polymer to the total matte particles is at least 15:1.
US08637218B2
A carrier for developing electrostatic latent image, including a core material; and a coated layer covering the core material, including a binder resin and a particulate material, wherein the core material is exposed on the surface of the carrier at an areal ratio of from 0.1 to 5.0% and has the largest exposed part having an areal ratio not greater than 0.03%, and wherein the coated layer comprises the particulate material in an amount of from 100 to 500 parts by weight per 100 parts by weight of the binder resin.
US08637214B2
Methods are provided for fabricating a semiconductor device. One method comprises providing a first pattern having a first polygon, the first polygon having a first tonality and having a first side and a second side, the first side adjacent to a second polygon having a second tonality, and the second side adjacent to a third polygon having the second tonality, and forming a second pattern by reversing the tonality of the first pattern. The method further comprises forming a third pattern from the second pattern by converting the second polygon from the first tonality to the second tonality forming a fourth pattern from the second pattern by converting the third polygon from the first tonality to the second tonality forming a fifth pattern by reversing the tonality of the third pattern, and forming a sixth pattern by reversing the tonality of the fourth pattern.
US08637208B2
The electrode for a fuel cell according to one embodiment of the present invention includes an electrode substrate and a catalyst layer disposed on the electrode substrate, the catalyst layer including metal nanoparticles, a binder and a catalyst. The metal nanoparticles in the catalyst layer improve electrical conductivity, and also have catalyst activity to implement a catalytic synergetic effect so as to provide a high power fuel cell.
US08637206B2
The invention provides catalysts which are not corroded in acidic electrolytes or at high potential and have excellent durability and high oxygen reducing ability. The catalysts include a niobium-containing oxycarbonitride having I2/(I1+I2) of not less than 0.25 wherein I1 is the maximum X-ray diffraction intensity at diffraction angles 2θ of 25.45 to 25.65 degrees and I2 is the maximum X-ray diffraction intensity at diffraction angles 2θ=2θ of 25.65 to 26.0 degrees according to X-ray powder diffractometry (Cu—Kα radiation).
US08637196B2
A device to produce electricity by a chemical reaction without the addition of liquid electrolyte comprises an anode electrode, a polymer membrane electrolyte fabricated to conduct hydroxyl (OH—) ions, the membrane being in physical contact with the anode electrode on a first side of the membrane, and a cathode electrode in physical contact with a second side of the membrane. The anode electrode and cathode electrode contain catalysts, and the catalysts are constructed substantially entirely from non-precious metal catalysts. Water may be transferred to the cathode side of the membrane from an external source of water.
US08637193B2
In some embodiments, the present disclosure provides a fuel cell catalyst having a catalyst surface bearing a non-occluding layer of iridium. In some embodiments, the present disclosure provides a fuel cell catalyst comprising a catalyst surface bearing a sub-monolayer of iridium. In some embodiments, the present disclosure provides a fuel cell catalyst comprising a catalyst surface bearing a layer of iridium having a planar equivalent thickness of between 1 and 100 Angstroms. In some embodiments, the fuel cell catalyst comprises nanostructured elements comprising microstructured support whiskers bearing a thin film of nanoscopic catalyst particles. The layer of iridium typically has a planar equivalent thickness of between 1 and 100 Angstroms and more typically between 5 and 60 Angstroms. The fuel cell catalyst typically comprises no electrically conductive carbon material and typically comprises at least a portion of the iridium in the zero oxidation state.
US08637186B2
An electrode for a battery and a method for manufacturing the same are disclosed. The electrode for a battery according to the present invention comprising silicon nanostructures integrally formed on a silicon thin film and having a period array can reduce the internal resistance, have better charge transport properties, and reduce the structural stress, thereby exhibiting high storage capacity, high efficiency charge/discharge characteristics, and long charge/discharge cycle characteristics. Moreover, the method for manufacturing the electrode for a battery according to the present invention can simply and easily form a nanopattern with nanostructures on a silicon thin film using laser interference lithography (LIL) and dry etching.
US08637179B2
A battery which can be assembled by using reduced man-hours. The battery has a battery cell having a positive electrode terminal and a negative electrode terminal which are arranged on one side surface of the battery cell, a circuit board placed facing the one side surface of the battery cell and having a first board terminal and a second board terminal, a first conduction member for conducting the positive electrode terminal and first board terminal to each other, a second conductive member for conducting the negative electrode terminal and the second board terminal to each other, a first cover placed between the circuit board and the battery cell, a second cover placed facing the first cover with the circuit board sandwiched between the first and second covers, a connection section for connecting the first and second covers to each other, and a cover for covering the circuit board. The circuit board is mounted to the one side surface of the battery cell while being sandwiched between the first and second covers.
US08637171B2
The invention relates to a device comprising a reactor, where the reactor comprises an anode compartment and a cathode compartment, and where the anode compartment comprises a) an anodophilic micro-organism capable of oxidizing an electron donor compound, and b) a living plant or part thereof. The invention also relates to a method for converting light energy into electrical energy and/or hydrogen, where a feedstock comprising an electron donor compound is introduced into the device.
US08637140B2
A method for defining an electrically conductive metalized structure, which may comprise an electrode or trace, on the surface of a three-dimensional element. The three-dimensional element may comprise a glass microsphere or shell resonator. A laser direct write grayscale photolithographic process is used in conjunction with electrically conductive metal deposition processes to define one or more electrically conductive metal structures on the surfaces of the three dimensional element.
US08637127B2
Embodiments of the present invention include composite articles comprising at least a first region and a second region and methods of making such articles. The first region may comprise a first composite material, wherein the first region comprises less than 5 wt. % cubic carbides by weight, and the second region may comprise a second composite material, wherein the second composite material differs from the first composite material in at least one characteristic. The composite article may additionally comprise at least one coolant channel. In certain embodiments, the first and second composite material may individually comprise hard particles in a binder, wherein the hard particles independently comprise at least one of a carbide, a nitride, a boride, a silicide, an oxide, and solid solutions thereof and the binder comprises at least one metal selected from cobalt, nickel, iron and alloys thereof. In specific embodiments, the first composite material and the second composite material may individually comprise metal carbides in a binder, such as a cemented carbide.
US08637115B2
Certain embodiments of the invention may include systems and methods curing a coated optical fiber. The method includes drawing the coated optical fiber through a gas chamber filled with a predetermined gas, drawing the fiber through a cure tube coupled to the gas chamber, and purging at least a portion of an inner surface of the cure tube with a purge gas as the coated optical fiber is drawn through the cure tube.
US08637113B2
A method of forming a non-volatile resistive oxide memory array includes forming a plurality of one of conductive word lines or conductive bit lines over a substrate. Metal oxide-comprising material is formed over the plurality of said one of the word lines or bit lines. A series of elongated trenches is provided over the plurality of said one of the word lines or bit lines. A plurality of self-assembled block copolymer lines is formed within individual of the trenches in registered alignment with and between the trench sidewalls. A plurality of the other of conductive word lines or conductive bit lines is provided from said plurality of self-assembled block copolymer lines to form individually programmable junctions comprising said metal oxide-comprising material where the word lines and bit lines cross one another.
US08637111B2
Methods for modulating the release rate of a drug coated stent are disclosed.
US08637103B2
Described herein are methods for preparing isomaltooligosaccharides (“IMOs”) from a carbohydrate substrate and uses thereof. In the presence of a maltogenic enzyme and additional IMO precursors, an Aspergillus sp. invertase is capable of producing IMOs from a starch slurry. The ability of the invertase to function as a transglucosidase enzyme imparts a simultaneous mechanism for IMO saccharification.
US08637094B2
An antiviral composition and a method of treating viral conditions comprising colloidal silver, silver nitrate, or both, and an antiviral natural herb or a natural herb from the Rutaceae family, such as Ruta graveolens, Myrtaceae family, such as Melaleuca alternifolia, Cupressaceae family, such as Thuja occidentalis, and the Moraceae family, such as fig, or any combination thereof.
US08637093B2
A composition for topical application to the skin comprises a cocoa polyphenol extract in combination with an SUS-rich fat, wherein the cocoa polyphenol extract is present in an amount of less than 15% by weight based on the weight of the SUS-rich fat, and a cosmetically acceptable carrier. The composition and the extract that it contains may increase skin elasticity and thickness and/or have an anti-wrinkle effect, may cause the depigmentation of age spots, improve skin renewal and/or reduce skin dryness such as reducing discomfort of chapped hands.
US08637092B2
The present invention relates to methods for preparing a pharmaceutical composition for treating diabetes mellitus and the pharmaceutical composition prepared by the methods. The pharmaceutical composition of the present invention comprises extracts of the following crude drugs: 5-40 weight parts of Radix Trichosanthis (Tianhuafen), 10-30 weight parts of Radix Bupleuri (Chaihu), 3-15 weight parts of Fructus Aurantii Immaturus (Zhishi), 1-6 weight parts of Radix et Rhizoma Rhei (Dahuang), 1-12 weight parts of Rhizoma Pinelliae (Banxia), 3-15 weight parts of Radix Scutellariae (Huangqin), 1-12 weight parts of Rhizoma Coptidis (Huanglian), 3-15 weight parts of Radix Paeoniae Alba (Baishao) and 5-20 weight parts of Fructus Mume (Wumei), and optionally comprises pharmaceutically acceptable excipient. Also, the pharmaceutical composition of the present invention can further comprise Fructus Crataegi (Shanzha). Additionally, the present invention discloses four methods for preparing the pharmaceutical composition.
US08637091B2
The present invention provides a composition comprising functional mineral that is substantially free of crystalline silica. The agricultural particle film composition may be applied to horticultural plants and animals.
US08637090B2
A method and composition for treatment of bacterial infections caused by gram negative or gram positive bacteria such as Staphylococcus aureus, Rhodococcus equi, Mycobacterium tuberculosis, Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a formulation containing gallium (III), in a pharmaceutically acceptable salt or complex thereof.
US08637077B2
Sustained release preparations, which show suppressed initial release of a physiologically active substance and can release a constant amount of the physiologically active substance over a long period of time, and dispersion vehicle thereof can be obtained by adding a cationic substance or polyols to the outside of a matrix or dispersion vehicle thereof. Thus, sustained release preparations, which show suppressed initial release of a physiologically active substance immediately after the administration and can release a constant amount of the physiologically active substance over a long period of time and dispersion vehicle thereof can be provided.
US08637070B2
Described herein are liquid rapamycin formulations. Described herein are methods of treating or preventing diseases or conditions, such as choroidal neovascularization, wet AMD and dry AMD, and preventing transition of dry AMD to wet AMD, using the liquid rapamycin formulations described herein.
US08637065B2
Methods for inducing differentiation of dermis-derived cells to serve as a source of chondrocytes and associated methods of use in forming tissue engineered constructs. One example of a method is a method for inducing differentiation of cells into chondrocytes comprising providing aggrecan sensitive isolated dermis cells and seeding the cells onto an aggrecan coated surface.
US08637064B2
A process for making an implantable material comprising a composite of a biocompatible polymer and a bioactive agent. The composite combines desirable mechanical properties of polymers and the bioactivity of tissue or one or more component of tissue. More particularly, but not exclusively, the invention relates to methods for the manufacture of implantable materials, devices and components via a powder molding process.
US08637060B2
A spot-on pesticide composition for animals, specifically mammals, including dogs and cats, which composition comprises a combination of active components, including fipronil and a pyrethroid, and optionally an insect growth regulator, in doses and proportions which are parasiticidally effective against a variety of insects and pests, and in a formulation which is convenient for local application to the animal's skin, preferably localized over a small surface area.
US08637059B2
The present invention relates to mixtures comprising as active components a) carbamate derivatives of the formula (I) in which the substituents and the index have the following meaning: T is CH or N n is 0, 1 or 2 R is halogen, C1-C4-alkyl or C1-C4-haloalkyl, it being possible for the radicals R to be different when n is 2, and b) at least one compound of the formula (II).
US08637054B2
This invention concerns an ophthalmic solution including: at least one prostaglandin; a solubilizing agent; a gelling agent of the carbomer type; a carbomer polymerization-inhibiting agent; a co-gelling/co-solubilizing agent.
US08637048B2
The present invention provides compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccharide at a concentration of no greater than about 10.0 endotoxin units per milliliter. The present invention also provides methods of making and methods of using such compositions, including inducing the production of antibody in an animal.
US08637043B2
The inventors have discovered that a CKβ8-1 truncation variant, CKβ8-1 (25-116), is a bifunctional ligand for two distinct GPCRs, chemokine receptor CCR1 and formyl peptide receptor like 1 (FPRL1). Hence, the inventors have discovered that, in addition to its functional activity on CCR1, CKβ8-1(25-116) is also a functional ligand for the GPCR receptor FPRL1 that is involved in inflammatory reactions and innate immunity by recruiting monocytes and neutrophils. In addition, the inventors have discovered an alternatively spliced exon of CKβ8-1, named SHAAGtide. SHAAGtide, along with its parent chemokine CKβ8-1 (25-116), is fully functional on both monocytes and neutrophils that are known to express FPRL1.This application relates generally to enhancing immune responses. Such immune responses may be elicited by vaccine administration. Compositions and methods for inducing or enhancing an immune response to an antigen are provided. The compositions and methods are useful for vaccine formulations for therapeutic and prophylactic use (immunization) and for production of antibodies.
US08637040B2
Peptides generated from a random library that are bound by a monoclonal antibody to Chlamydial glycolipid exoantigen (GLXA) and thus mimic this antigen are disclosed. Peptides that correspond to antigen-binding regions of an anti-idiotypic antibody (mAb2) specific for anti-GLXA antibody (Ab1) which act as molecular mimics of GLXA are also disclosed used as immunogens to induce broadly reactive genus-specific anti-chlamydial antibodies. These peptides and immunogenic DNA encoding the mAb2-like peptides, microparticle or nanoparticle formulations and other formulations of these peptides are disclosed as are methods for immunizing subjects to obtain genus-specific anti-chlamydial antibodies and to treat or prevent Chlamydia-associated or induced rheumatoid arthritis.
US08637037B2
The present invention concerns the preparation of purified allergens and allergoids, both derived from whole bee venom, for the desensitization (immunotherapy) of subjects affected by a specific allergy. In particular, the present invention concerns a preparation for immunotherapy based on purified bee venom, characterized in that said bee venom is essentially mellitin-free. In addition, the preparation of a monomeric allergoid obtainable through the carbamylation or thiocarbamylation reaction of said mellitin-free bee venom, is described. Said allergoid, being characterized by reduced IgE-binding activity, may be a safer and more effective candidate for specific immunotherapy.
US08637034B2
The preset invention relates to combination pharmaceutical composition comprising an activated-potentiated from of an antibody to gamma interferon, and an activated-potentiated form of an antibody to S-100 protein and method of treating multiple sclerosis and other neurodegenerative diseases, as well as the diseases and conditions associated with neuroinfections.
US08637030B2
The present invention provides a combination pharmaceutical composition comprising a) an activated-potentiated form of an antibody to a S-100 protein, b) an activated-potentiated form of an antibody to histamine, and c) an activated-potentiated form of an antibody to TNF-alpha. Various embodiments and variants are provided. The present invention further provides a method of treating a disease or condition of functional etiology of the gastrointestinal tract, said method comprising administering to a patient in need thereof a combination pharmaceutical composition comprising a) an activated-potentiated form of an antibody to a histamine, b) an activated-potentiated form of an antibody to S-100 protein and c) an activated-potentiated form of an antibody to TNF-alpha. Various embodiments and variants are provided.
US08637024B2
Disclosed herein are fusion antibodies created to provide both an antigen-binding site that targets the CD4 receptor and an antigen-binding site that targets the HIV envelope. The fusion antibodies disclosed herein provide improved potency and breadth against HIV as compared to monospecific antibodies, and additionally provide high barrier against viral resistance. Also disclosed are pharmaceutical formulations and therapeutic methods utilizing such fusion proteins.
US08637014B2
This disclosure provides methods and compositions for inhibiting immune responses. The disclosure also provides methods and compositions for inhibiting graft rejection and promoting or prolonging graft survival.
US08637009B2
Provided are compositions comprising a cocaine esterase (CocE) and a compound that thermostabilizes the CocE. Also provided are methods of thermostabilizing a cocaine esterase. Additionally provided are methods of treating a mammal undergoing a cocaine-induced condition. Methods of determining whether a compound is a thermostabilizing agent for a protein are also provided. Uses of the above-described compositions for the treatment of a cocaine-induced condition is additionally provided. Additionally provided is an isolated nucleic acid encoding a CocE polypeptide having the substitutions L169K and G173Q, and the CocE polypeptide encoded by that nucleic acid, and pharmaceutical compositions thereof. Further provided is the use of that composition for the manufacture of a medicament for the treatment of a cocaine-induced condition and for the treatment of a cocaine-induced condition.
US08637008B2
Embodiments presented herein relate to various polymers. Some of the polymer embodiments are heparin binding polymers. Some embodiments of the heparin binding polymers can be employed to bind to heparin for methods such as separating, purifying, removing, and/or isolating heparin and heparin like molecules.
US08637005B2
The present invention relates to pharmaceutical compositions comprising a chemotactic hematopoietic stem cell product comprising an enriched population of CD34+ cells containing a subpopulation of CD34+/CXCR-4+ cells having CXCR-4-mediated chemotactic activity, methods of preparing these compositions and use of these compositions to treat or repair vascular injury, including infarcted myocardium.
US08637002B2
Non-toxigenic strains of Aspergillus are useful biocontrol agents for preventing toxin contamination in agricultural commodities, especially those for human consumption such as peanuts and corn, for example.
US08636987B2
A method of whitening a tooth surface including contacting the surface of a tooth with an efficacious amount of a substantially non-cytotoxic composition. The non-cytotoxic composition includes chlorine dioxide and no more than about 0.25 milligrams oxy-chlorine anions per gram of the composition.
US08636985B2
Nutraceutical gum or functional food compositions comprise Ashwagandha (Withania somnifera) and L-theanine in a sublingual formulation. Methods of making suitable sublingual formulations are described. Also provided is a method for reduction of stress and/or enhancement of energy and mental clarity, comprising administering to an individual in need thereof an effective amount of a nutritional composition comprising Ashwagandha herb and L-theanine, and a nutraceutically acceptable carrier, wherein the nutritional composition is administered sublingually.
US08636983B2
The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
US08636979B2
The present invention concerns a pharmaceutical composition comprising at least one agonist of at least one Toll Like receptor (TLR) chosen from TLR 4 and 9, for use in the prophylactic treatment of septic complications of post-traumatic systemic immunodepression in a patient who has suffered one or more severe traumatic injuries and is hospitalized in particular in an intensive care unit. Preferably, said TLR 4 agonist is monophosphoryl lipid A (MPLA) or deacylated 3-O-monophosphoryl lipid A (3D-MPLA) and said TLR 9 agonist is a CpG oligodeoxynucleotide (CpG ODN).
US08636978B2
Cyclized peptide compounds containing the NGR motif of formula (I) or a pharmaceutically-acceptable salt thereof are disclosed. Compositions comprising the cyclized peptide compounds and methods of their use are also disclosed.
US08636973B2
The present invention relates to means and methods for producing crystals or crystalline substances. In particular, crystals or crystalline substances which are useful as pharmaceutical ingredients can be manufactured.
US08636972B1
Processing a composite material includes forming a nanomaterial comprising nanotubes. The nanotubes comprise first nanotubes and second nanotubes, where the first nanotubes and the second nanotubes have different lengths. The nanomaterial is combined with a matrix to yield a composite material.
US08636961B2
The present invention increases the amount of hydrogen produced or released from reactions between a metal hydride fuel and liquid reactant. The present invention also decreases the volume of a hydrogen generating cartridge by reducing the pH of the liquid reactant.
US08636958B2
A nozzle reactor includes a passage having one or more regions with a converging-diverging shape. The nozzle reactor accelerates a reacting fluid to supersonic velocities and mixes it with a feed material. The reacting fluid and the feed material may be pre-heated. The high speed collision between the reacting fluid and the feed material at elevated temperatures causes the materials to react.
US08636956B2
A sensor main unit 1 is axially split into three sub-segments. A light-emitting element 2 is attached to one end portion, and a light-receiving element 3 is attached to the other end portion. A respiratory flow path 4 is formed so as to penetrate through the center portion. The sensor main unit 1 is attached to a position on the face below the nostrils, and respiratory gas from the nostrils is guided into the respiratory flow path 4 and is caused to cross over the optical axis connected the light-emitting element 2 and the light-receiving element 3, thereby measuring a carbon dioxide gas in the respiratory gas.
US08636945B2
A method for producing crystalline particles including a mixing step of producing a mixed material containing a lead-containing material and an additional material containing lithium and boron and a first firing step of firing the mixed material at a predetermined firing temperature to form polyhedral crystalline particles. The crystalline particles are used to produce a crystallographically oriented ceramic by preparing a template layer having uniform crystal orientation in a predetermined direction by fixing the crystalline particles on a substrate, forming a shaped body including a matrix layer arranged on the template layer, the matrix layer being composed of a mixed material that contains a lead-containing material and an additional material containing lithium and boron, and firing the shaped body.
US08636944B2
A method of plastic container having a deep inset base of the type that has a standing ring for supporting the container on a flat surface includes steps of molding a container blank having a standing ring and a base projection portion that is formed beneath the standing ring and relatively displacing the base projection portion upwardly with respect to the standing ring until the base projection portion is positioned above the standing ring. An improved plastic container having a deep inset base is also disclosed.
US08636943B2
Process for manufacturing a fuel tank equipped with an internal accessory and having a plastic wall produced from a parison, said process comprising, in order, the following steps: a) the accessory and the molten parison are introduced into a mold so that the accessory is surrounded by the parison, said mold comprising cavities equipped with at least one moving part; b) a pressurized gas is introduced inside the parison to carry out a pre-blow molding of said parison; c) the pre-blow-molded parison is pressed locally against the accessory using the moving part in order to firmly attach the two without piercing the parison; d) the mold is closed and the final blow molding of the parison is carried out by flattening it against the mold cavities using the pressurized gas; and e) the tank is removed from the mold.
US08636937B2
A method for forming hierarchical patterns on an article by nanoimprinting is disclosed. The method includes using a first mold to form a primary pattern on the article at a first temperature and a first pressure, the first temperature and the first pressure being able to reduce the elastic modulus of the article; and using a second mold to form a second pattern on the primary pattern at a second temperature that is below the article's glass transition temperature, the forming of the second pattern being at a second pressure.
US08636934B2
Signage is presented comprising an in-mold plastic plate portion having a slot. The signage has a flexible tongue having a neck portion that extends outwardly from the plate portion and has a locking tip extending from the neck portion and the locking tip is formed to be received by the slot. The plastic plate portion is made of a filler material and a detectable additive such that the signage is easily detected by a metal detecting machine.
US08636933B2
Method for producing a pressed powder element, wherein the method comprises pre-pressing of loose powder to a first powder blank (14), pre-pressing of loose powder to a second powder blank (15) and pressing together the at least two pre-pressed powder blanks (14, 15) to form a pressed powder element as well as the corresponding apparatus.
US08636929B2
Process for the production of nanoporous foamed active substance-containing preparations, wherein the active substance is present embedded in a pharmaceutically acceptable polymer, wherein, in stage a) loading of a polymeric molding composition or a polymer melt with a propellant is effected at a pressure and at a temperature at which the propellant is in the supercritical state, in stage b) heating of the laden polymer molding compound or melt is carried out under pressure at a temperature which lies in the range from −40 to +60° C., preferably −20 to +55° C., and especially preferably 0 to +50° C. around the glass transition temperature of the unladen (prior to loading) polymeric molding compound and in stage c) a depressurization of the polymeric molding compound or melt laden in stage a) and heated under pressure in stage b) is effected out with a depressurization rate in the range from 15,000 to 200,000 MPa/sec.
US08636928B2
The invention provides methods of making provisional and long-term dental restorations, particularly dental veneers, implants, crowns and bridges. A shell or restoration form made of polymerizable material having good dimensional shape-stability in its uncured condition is used to make the dental restoration. A polymerizable material is introduced into the cavity of the shell form. The outer shell and injected polymerizable material are polymerized and bond together to form a hardened crown structure. In one embodiment, the restoration can be fabricated indirectly by a dental laboratory. In another version, a dental practitioner can make the restoration chairside for a patient in a dental office.
US08636918B2
A composition includes an anionic polysaccharide hybrid polymer composition and 2-phosphonobutane-1,2,4-tricarboxylic acid. In one embodiment, the polysaccharide hybrid polymer composition includes a polysaccharide residue present in an amount from approximately 5% to approximately 90% by weight of the polysaccharide hybrid polymer composition and a residue of at least one ethylenically unsaturated monomer present in an amount from approximately 10% to approximately 75% by weight of the polysaccharide hybrid polymer composition.
US08636917B2
A solution for forming a polishing slurry, the polishing slurry and related methods are disclosed. The solution for forming a polishing slurry may include 1H-benzotriazole (BTA) dissolved in an ionic surfactant such as a sodium alkyl sulfate solution, and perhaps a polyacrylic acid (PAA) solution. The solution can be filtered and used in a polishing slurry. This approach to solubilizing BTA results in a high BTA concentration in a polishing slurry without addition of foreign components to the slurry or increased safety hazard. In addition, the solution is easier to ship because it is very stable (e.g., can be frozen and thawed) and has less volume compared to conventional approaches. Further, the polishing slurry performance is vastly improved due to the removal of particles that can cause scratching.
US08636916B2
A method of forming an electrolyte solution involves combining ammonium tetrafluoroborate and a quaternary ammonium halide in a liquid solvent to form a quaternary ammonium tetrafluoroborate and an ammonium halide. The ammonium halide precipitate is removed from the solvent to form an electrolyte solution. The reactants can be added step-wise to the solvent, and the method can include using a stoichiometric excess of the ammonium tetrafluoroborate to form a substantially halide ion-free electrolyte solution. Filtration can be done at low temperatures to reduce the amount of excess bromide in the resulting electrolyte.
US08636915B2
To provide a liquid processing apparatus capable of processing substrates with a high throughput with the lesser number of nozzles for chemical-liquid, when the substrates that are horizontally held in cup bodies are liquid-processed by supplying a chemical liquid to the substrates. Taking a developing process as an example of a liquid process, two-types of developing nozzles are prepared for two types of developing methods. The developing nozzle, which is used in the method in which the nozzle is engaged with the process for a longer period of time, is individually disposed on each of a first processing module 1 and a second processing module 2. On the other hand, the developing nozzle, which is used in the method in which the nozzle is engaged with the process for a shorter period of time, is used in common in the first liquid processing module 1 and the second liquid processing module 2. The common developing nozzle is configured to wait on an intermediate position between the modules 1 and 2.
US08636913B2
The present invention generally relates to a method of forming a magnetic head while ensuring residues do not negatively impact the magnetic head. In particular, when performing a RIE process to remove DLC, oxygen gas can leave residues that will negatively impact the RIE process performed on the next substrate to enter the chamber. By utilizing CO2 rather than O2, the residues will not be created and therefore will not impact processing of the next substrate that enters the chamber.
US08636907B1
A two-stage sealed magnetic filter continuously removes magnetic and non-magnetic contaminants from liquid process streams. Elongated non-magnetic holder sleeves encasing magnet bars attract magnetic contaminants while a screen cylinder captures non-magnetic contaminants. The magnet bars are accessible without having to open the interior of the housing to the environment. Thus, during maintenance, removing the magnet bars from the holder sleeves releases the magnetic contaminants that have adhered to the holder sleeves into the screen cylinder which partially encloses the holder sleeves. Contaminants are flushed out of the magnetic filter without exposing workers to potentially hazardous substances. Polymeric sludge occluded with iron compounds can be effectively removed from streams in refineries and chemical plants. The iron compounds are formed from carbon steel which is prevalent in plant machinery and that corrodes in the presence of acidic contaminants.
US08636898B2
A liquid transfer device having a housing with a top end, a bottom end, a sidewall, and an inner cavity. The sidewall has an inner surface and an outer surface. There is a plurality of openings traversing said sidewall. Also present is a filtering surface that covers the openings. The water or other liquids are pumped or transferred with a pump contained inside the inner cavity, with a fluid exit used for carrying the water out towards exterior hosing.
US08636897B2
A use of a foulant collector in a vessel or conduit in a paraffinic froth treatment (PFT) process. The foulant comprises asphaltenes. The foulant collectors are purposed to reduce build-up in the vessel or conduit and/or to reduce downstream foulant carry-over in the process. The surface of the foulant collectors may have an average water contact angle of less than 90 degrees. Additionally, together with such foulant collectors, a fluorocarbon polymer may be used as a surface of a vessel or conduit in the PFT process, for reducing fouling.
US08636896B2
The invention relates to a method for treating a hydrocarbons charge comprising the following stages, in which: a) the charge is brought into contact with a solvent in order to obtain a deasphalted effluent having a content of asphaltenes below 3000 ppm by weight, b) the deasphalted effluent is cracked in the presence of hydrogen and a hydrocracking catalyst, in a bubbling-bed reactor, so as to convert at least 50 wt. % of the fraction of the deasphalted effluent boiling above 500° C. to compounds having a boiling point below 500° C., c) the effluent from stage b) is fractionated to recover gasolines, kerosene, gas oils and a first residue, and d) at least a portion of this first residue is cracked so as to obtain an effluent comprising gasolines, kerosene, gas oils and a second residue.
US08636893B2
Chlorine with a low bromine content is produced by electrolyzing brine to produce gaseous chlorine, alkali metal hydroxide and hydrogen, separating the gaseous chlorine from the electrolyte (anolyte in the case of the membrane process), directing electrolyte (anolyte in the case of the membrane process) to a primary dechlorination step using hydrochloric acid to remove gaseous chlorine therefrom, optionally directing depleted electrolyte (anolyte in the case of the membrane process) from the primary dechlorination step to a secondary dechlorination step using a reducing agent for chlorine and oxychlorine species, and recycling dechlorinated depleted electrolyte (anolyte in the case of the membrane process) to salt dissolvers to prepare brine for electrolysis. At least part of the gaseous chlorine generated in the primary dechlorination step is not combined with gaseous chlorine generated in the electrolysis step.
US08636889B2
A solid electrolyte producing system includes a supercapacitor desalination device comprising a power supply and a supercapacitor desalination unit. The supercapacitor desalination unit includes a pair of electrodes electrically coupled to the power supply and operable in a charging mode of operation and a discharging mode of operation. A feeding source is configured to provide a feed liquid to the supercapacitor desalination unit when the supercapacitor desalination unit is in the charging mode of operation. The feed liquid comprises at least one determined electrolyte. A crystallization device is providing for receiving a concentrated liquid from the supercapacitor desalination device in the discharging mode of operation, the concentrated liquid being a saturated liquid or supersaturated liquid of the at least one determined type of electrolyte. The at least one determined type of electrolyte precipitates in the crystallization device as solid electrolyte. The system further comprises a separation device for separating the solid electrolyte from the liquid of the crystallization device as a solid electrolyte product.
US08636884B2
Embodiments of the invention include analyte-responsive compositions and electrochemical analyte sensors having a sensing layer that includes an analyte-responsive enzyme and a cationic polymer. Also provided are systems and methods of making the sensors and using the electrochemical analyte sensors in analyte monitoring.
US08636878B2
This is a device and process to generate alternating current without an external source for cell-houses in electro-winning or electro-refining of copper or other products in which the electric source consists of a conventional rectifier-transformer group that supplies continuous electrical current to the cell-house, which is connected in parallel to a device characterized by having the capacity to extract an electrical current from the cell-house for a period of time and then return it in another period of time, whether periodically or semi-periodically and without changing the average value of the electrical current, supplied to the cell-house by the rectifier-transformer. This results in an electrical current in the cell-house that is the superimposition of a continuous and alternating current. This process is designed to overcome the barrier of electric potential produced by the presence of the pure continuous electric field in cell-houses through the electric agitation of an ion-rich electrolyte.
US08636873B2
A structure, for use in a processing chamber of a plasma processing apparatus in which a plasma process is performed on a target substrate, includes a base member at least having a first surface and a second surface; and a thermally sprayed insulating film covering the first surface. Further, the structure includes an insulating protection member covering the second surface and made of a material having a linear expansion coefficient different from that of the base member; and an insulating layer interposed between the thermally sprayed insulating film and the insulating protection member to prevent a contact therebetween. The thermally sprayed insulating film, the insulating protection member and the insulating layer constitute an insulating surface covering the first surface and the second surface.
US08636867B2
A method for producing an escape route marking and the apparatus for an airplane comprising a luminous layer that luminesces in the dark, and a profile having two profile elements that can be connected to each other, wherein in a first of the profile elements, the luminous layer is arranged in a recess extending in the longitudinal direction, and the second profile element is provided to be connected with a base, wherein the procedure comprises the following steps: production of the luminous layer from a mixture of a silicone material and from photoluminescent pigments, and introduction of the mixture in a liquid state into the recess of the first profile element, wherein the mixture cures in the seat by crosslinking with the walls in the profile.
US08636865B2
The invention relates to a method for producing a composite component reinforced by stiffening elements.Composite component is produced by the inside gluing of a monolithic component to a multiplicity of stiffening elements by means of an adhesive suitable for this particular application. Stiffening elements are formed with a fiber reinforced, amorphous thermoplastic material. Monolithic component of composite component consists of a fiber reinforced duroplastic material—for example a composite epoxy matrix—in which are embedded, for reinforcement, carbon fibers, basalt fibers, natural fibers, ceramic fibers, Aramide® fibers, Kevlar® fibers or any combination thereof.Monolithic component is glued to thermoplastic stiffening elements by an adhesive under the influence of pressure and temperature. Here a tolerance compensation is carried out essentially by stiffening elements, if necessary being plastically deformed, so that high dimensional stability is achieved. Composite components, which can be subject to high mechanical loads, are therefore provided, in particular, as spare or replacement parts for outer lining parts on aircraft.The invention also relates to a composite component produced by means of a method according to the invention.
US08636854B2
A method for coating a flat steel product manufactured from a high strength steel with a metallic coating, wherein the flat steel product is initially subjected to a heat treatment, in order then, in the heated state, to be hot-dip galvanized with the metallic coating in a melting bath containing overall at least 85% zinc and/or aluminum. The heat treatment includes heating the steel product in a reducing atmosphere, followed by converting a surface of the flat product to an iron oxide layer by a heat treatment lasting 1 to 10 secs in an oxidizing atmosphere, followed by annealing in a reducing atmosphere over a period of time which is longer than the duration of the formation of the iron oxide layer such that the iron oxide layer is reduced at least on its surface to pure iron, followed by cooling the product to a melting bath temperature.
US08636850B2
Some demonstrative embodiments of the invention include an apparatus and a method for removing the support structures from three-dimensional objects, in which the support removal is carried out using techniques that decrease the duration of the support removal process and increase the quality of the final three-dimensional objects. This method also ensures the safe removal of the support structures without damage to the three-dimensional object.
US08636842B2
Disclosed is a method of manufacturing an artificial stone, and the method includes forming an artificial-stone paste which comprises 20-20 parts by weight of silica stone, metakaolim or silica fume, 200-300 parts by weight of quartz chips, 30-36 parts by weight if water, 1.5-3 part by weight of water-reducing agent and 0.2-3 parts by weight of pigment with response to 100 parts by weight of white cement; injecting the artificial-stone paste in a mold; primarily vacuum-molding the artificial-stone paste injected in the mold; secondarily vibration-molding the primarily molded artificial-stone paste; primarily curing the secondarily molded artificial-stone paste; secondarily curing the primarily cured artificial-stone paste, which induces a hydrothermal reaction and thus causes a pozzolanic reaction; releasing the secondarily cured artificial-stone paste from the mold; and surface-machining the released artificial-stone paste.
US08636829B2
The invention provides gas purification systems for the recovery and liquefaction of low boiling point organic and inorganic gases, such as methane, propane, CO2, NH3, and chlorofluorocarbons. Many such gases are in the effluent gas of industrial processes and the invention can increase the sustainability and economics of such industrial processes. In a preferred system of the invention, low boiling point gases are adsorbed with a heated activated carbon fiber material maintained at an adsorption temperature during an adsorption cycle. During a low boiling point desorption cycle the activated carbon fiber is heated to a desorption temperature to create a desorption gas stream with concentrated low boiling point gases. The desorption gas stream is actively compressed and/or cooled to condense and liquefy the low boiling point gases, which can then be collected, stored, re-used, sold, etc. Particular systems of the invention include an active condensation loop that actively cools and/or compresses a desorption gas stream from said vessel to liquefy low boiling point gases.
US08636821B2
A ceramic honeycomb structure having a large number of flow paths partitioned by porous cell walls, the cell walls meeting the conditions; (a) the cell walls having porosity of 55-80%, (b) the cell walls having a median pore diameter D50 (measured by mercury porosimetry) of 5-27 μm, (c) pores open on cell wall surfaces having an opening area ratio of 20% or more, (d) pores open on cell wall surfaces having a median opening diameter d50 (determined from equivalent circle diameters on an area basis) of 10-45 μm, (e) the density of pores open on cell wall surfaces having equivalent circle diameters of 10 μm or more and less than 40 μm being 350/mm2 or more, (f) the maximum inclination of a curve of a cumulative pore volume relative to a pore diameter (determined from a pore distribution measured by mercury porosimetry) being 1.6 or more, and (g) a ratio D50/d50 of the median pore diameter D50 to the median opening diameter d50 being 0.65 or less.
US08636816B1
A composite wood product adapted for burning includes a compacted mixture of lignosulfonate, wood particles, and ground corn. A method of manufacturing the composite wood product includes: (i) providing and mixing the lignosulfonate, the wood particles, and the ground corn to form a mixture having a moisture content from about 6 wt. % to about 18 wt. %; compacting the mixture at high pressure; and drying the mixture to obtain an optimum moisture level for burning. The composite wood product may be provided in a kit that includes log-shaped pieces and starter pieces.
US08636806B2
A biologic diarthrodial joint includes an artificial subchondral bone shaped in the form of a joint replacement member and formed of an artificial fiber material. The artificial fiber material includes synthetic fibers formed in a fibrous network with the synthetic fibers arranged in multiple orientations. The artificial subchondral bone includes a polymer receiving component. An artificial cartilage polymer is cooperable with the artificial subchondral bone and engages the polymer receiving component. The artificial cartilage polymer has physical properties similar to that of native articular cartilage.
US08636790B2
A vascular stent to be implanted in a vessel of a living body to scaffold the vessel from inside is provided. The stent includes a tubular body formed by assembling a plurality of tubular-body forming elements constituting a part of a tubular body. The tubular-body forming elements are formed by bending a strand made of a biodegradable polymer such that legs as linear parts and bend parts alternate in sequence, to form a single flow channel from one end to the other end. The plurality of tubular-body forming elements constitute the tubular body by connecting and unifying two connecting members by melt welding, each of the connecting members being attached to adjacent portions of the plurality of tubular-body forming elements.
US08636789B2
A stent graft defining a main lumen bounded by a wall of graft material is disclosed. The stent graft has a valve portion between proximal and distal portions. The valve portion is formed by a wall portion having a part-circumferential double layer portion comprising an inner underlap portion and an outer overlap portion, the double layer portion forming a passageway parallel to the main lumen. The passageway has an entrance mouth and an exit mouth. The passageway has an open condition where the underlap and overlap portions are spaced apart to form a vent lumen. The wall portion is broken by a narrow cut. The cut is openable by relative radial movement between its edges. This allows re-perfusion of an aneurism and perfusion of blood from within the lumen out towards blood vessels such as intercostals and can assist in minimizing the chance of paraplegia.
US08636786B2
An eye compress kit includes a thermally adjustable gel pack, a strap and at least one moistened, disposable fibrous non-woven fabric sheet. The thermally adjustable gel pack is configured to be applied against an eye region of a user's body. The gel pack includes a casing that defines a chamber holding a thermally activatable gelatinous substance. The strap is configured to secure the gel pack against the user's eye region and to exert compressive forces to the gel pack. The at least one moistened, disposable fibrous non-woven fabric sheet is adapted to be positioned between the gel pack and the user's eye region wherein the fabric sheet is removable from the outer surface of the gel pack.
US08636784B2
An attachment device with a radially expandable section is disclosed. The attachment device can have helical threads, for example, to facilitate screwing the attachment device into a bone. Methods of using the same are also disclosed. The attachment device can be positioned to radially expand the expandable section in cancellous bone substantially surrounded by cortical bone.
US08636781B2
A receiving part for receiving a rod for coupling the rod to a bone anchoring element includes a receiving part body including a rod receiving portion with a channel for receiving a rod, and a head receiving portion for accommodating a head of a bone anchoring element, the head receiving portion having an open end and being flexible so as to allow introduction and clamping of the head, the head receiving portion having an exterior surface with a tapered portion; and a locking ring around the head receiving portion and including an interior surface with a curved portion configured to engage the tapered portion of the exterior surface of the head receiving portion to clamp the head.
US08636777B2
A polyaxial bone screw assembly includes a threaded shank body having an upper capture structure, a head and an open, compressible retainer collar. The capture structure and retainer collar are both threaded for rotatable attachment within a cavity of the head. The head has a U-shaped cradle defining a channel for receiving a spinal fixation rod. The head channel communicates with the cavity and further with a restrictive opening that allows for loading the capture structure into the head but prevents passage of the attached retainer collar out of the head. The open retainer collar may be bottom- or top-loaded by compressing open ends of the ring towards each other, the collar springing back into a rounded shape after insertion in the head. The open collar has an external substantially spherical surface that mates with an internal surface of the head, providing a ball joint, enabling the head to be disposed at an angle relative to the shank body. The threaded capture structure includes a tool engagement formation and gripping surfaces for non-slip engagement by a tool for driving the shank body into bone.
US08636770B2
A bone anchoring device including a clamping device and a flexible band configured to be secured a vertebra. The clamping device includes a base member and an upper member configured to be secured together with a fastener. The flexible band is configured to be passed around a bone portion and through a passage of the base member to position the flexible band between a clamping surface of the base member and a clamping surface of the upper member. The flexible band is tensioned to urge the clamping device against the bone portion and then clamped between the clamping surfaces of the base member and the upper member. A stabilization member of a vertebral stabilization construct may be secured to the vertebra with the bone anchoring device without invasively altering or impairing the structural integrity of the vertebra.
US08636768B2
A pacifier having a nipple, which can be fastened to the pacifier guard with a stem-shaped end, wherein on the pacifier guard a fastening part that is or can be connected to the pacifier is provided on a side provided for placing the lips thereon such that the pacifier is connected to the pacifier guard when the fastening part is fastened to the pacifier guard.
US08636756B2
The tissue approximating structures for the anastomosis devices of the invention preferably include two sets of approximating structures or tines spaced from each other along the length of a catheter body that can be extended and retracted from the catheter body. Each of the sets of tissue approximating structures is preferably sequentially deployable in such a way that the surgeon can activate a first set of tines to engage a first tissue structure, verify that an adjacent second tissue structure is properly positioned relative to the first tissue structure, then activate a second set of tines to engage that adjacent second tissue structure. Each of the sets of tines is preferably controlled by a single actuation mechanism that is attached to the anastomosis device and is positioned outside the patient's body.
US08636745B2
An orthopedic drill guide and surgical pin positioning device includes a primary surgical pin for insertion into a fractured bone and a longitudinal drum supported on said primary surgical pin. A set screw is also provided in said longitudinal drum for preventing the longitudinal drum from rotation about the primary surgical pin. A transverse drum is also provided and is rotatably disposed in the longitudinal drum as is a set screw for fixing the position of the transverse drum with respect to the longitudinal drum. A secondary pin extends through the transverse drum and is fixed in a second position on the hard tissue of the fractured bone. Finally, a pair of aligned openings extends through the transverse drum for guiding a drill bit and locating a surgical pin within the broken bone.
US08636742B2
Methods and devices are provided for reducing a spinal fixation element into a spinal implant element. In one exemplary embodiment, a spinal rod reduction device is provided for reducing a spinal fixation element into a spinal implant element. The spinal rod reduction device can include a fastener engaging member for engaging at least a portion a spinal implant element, a reduction member for engaging at least a portion of a spinal fixation element, and a handle assembly mated to the reduction member. The handle assembly can be designed in such a way that actuation of the handle assembly causes movement of the reduction member relative to the fastener engaging member and the movement of the reduction member reduces the spinal fixation element into the spinal implant element. Two different styles of spinal rod reduction devices are discussed in detail. Various techniques are also provided for reducing a spinal fixation element into a spinal implant element.
US08636740B2
A spinal stabilization system includes an implant and instrumentation for stabilizing the spine. In one embodiment, the system includes a plate having a side rail and a channel extending adjacent the side rail. A pedicle screw assembly is positioned in the channel in releasable engagement with the side rail. The pedicle screw assembly includes a polyaxial screw seated in a lower housing having a lower locking flange. An upper housing having an upper locking flange secures the plate to the lower housing. The side rail of the plate is releasably engaged between the upper locking flange and the lower locking flange. The upper and lower housings include on-board locking mechanisms for fixing components in the screw assembly. The screw assembly and plate are inserted and oriented by remote manipulation. Minimally invasive techniques for inserting the implant are performed with the instrumentation, and cause minimal disturbance to surrounding tissue.
US08636728B2
A balloon elongation apparatus includes an elongated hypotube with a distal end having a reduced inner diameter portion that is configured to radially expand when a mandrel is advanced through a lumen of the hypotube towards the reduced inner diameter portion. A medical kit includes a catheter having a distally-located balloon and the elongation apparatus disposed within a guide wire tube of the catheter. In use, the balloon is elongated following a procedure in order to facilitate retracting the balloon into a sheath. The balloon is elongated by first advancing the mandrel relative to the hypotube so that the hypotube radially expands and firmly engages an inner surface of the guide wire tube and then advancing the mandrel, hypotube, and distal end of the guide wire tube relative to the catheter body.
US08636715B2
Catheter devices having low profile shafts and laterally deployable members (e.g., cannulas, needles, etc.) that may be extended or advanced laterally from the catheter shaft. Also disclosed are methods for bypassing a vascular obstruction (e.g., a chronic total occlusion or other full or partial obstruction) wherein a guidewire is entrapped in a subintimal space adjacent to the obstruction. A catheter of the foregoing character is advanced over the entrapped guidewire and into the subintimal space. The laterally deployable member is then advanced or extended from the subintimal space back into the true lumen of the blood vessel distal to the obstruction. A second guidewire is then advanced through or along the laterally deployable member. The catheter and first guidewire are then removed and one or more working device(s) (balloons, atherectomy devices, setnts, etc.) is/are advanced over the second guidewire and used to establish a subintimal bypass channel through which blood may flow around the obstruction.
US08636711B2
Stabilized glucagon solutions, methods of storing and using the stabilized glucagon solutions, and drug delivery devices containing the stabilized glucagon solutions. In some embodiments, the glucagon solutions may be alkaline, such as with a pH of at least about 9. The glucagon solutions may be resistant to aggregation of glucagon when the solutions are stored for a prolonged period, such as at least about three days, at room temperature and/or physiological temperature.
US08636709B2
The invention relates to the treatment of wounds. In particular, the invention relates to systems, devices, and methods enabling pulse lavage irrigation of wounds in a non-controlled setting while providing containment of contaminated irrigation fluid, thereby preventing exposure of individuals and surfaces in proximity to the patient to infectious materials.
US08636706B2
Transfer sets are disclosed in the present patent. The transfer set provides a connection between a source of peritoneal dialysis fluid and a patient for whom peritoneal dialysis has been prescribed. The transfer sets disclosed herein are smaller and provide a more compact and convenient device by which a dialysis patient controls the flow of dialysis fluid to and from the peritoneum of the patient. The devices are more compact and convenient because they include more convenient mechanisms for starting and stopping flow of the dialysis fluid. It is also easy to determine whether the mechanism is in a closed or open configuration by simply looking at the mechanism.
US08636669B2
A cardiac rhythm management system provides for ambulatory monitoring of hemodynamic performance based on quantitative measurements of heart sound related parameters for diagnostic and therapeutic purposes. Monitoring of such heart sound related parameters allows the cardiac rhythm management system to determine a need for delivering a therapy and/or therapy parameter adjustments based on conditions of a heart. This monitoring also allows a physician to observe or assess the hemodynamic performance for diagnosing and making therapeutic decisions. Because the conditions of the heart may fluctuate and may deteriorate significantly between physician visits, the ambulatory monitoring, performed on a continuous or periodic basis, ensures a prompt response by the cardiac rhythm management system that may save a life, prevent hospitalization, or prevent further deterioration of the heart.
US08636668B2
Provided is a measuring apparatus that includes: a semiconductor laser device that emits a laser light beam to an object to be measured; a driving unit that provides a driving signal for modulation drive of the semiconductor laser device; a first detection unit that detects a first electrical signal that corresponds to the intensity of the laser light beam modulated due to the self-coupling effect, in a first half-cycle of the driving signal; a second detection unit that detects a second electrical signal that corresponds to the intensity of a second laser light beam modulated due to the self-coupling effect, in a second half-cycle of the driving signal being in an opposite phase of the first half-cycle; a calculation unit that calculates a difference between the first and second electrical signals; and a measuring unit that measures a change in the state of the object based on the calculated difference.
US08636666B2
Rendering quality parameter values are automatically set or adjusted as a function of acquisition ultrasound parameter values. The rendering quality is automatically selected based on the acquisition quality, such as providing for a higher quality or quality rendering for slower acquisitions. More than two rendering states are provided for a respective, more than two different quality settings.
US08636662B2
Methods and systems for displaying system parameter information are provided. One method includes determining a value for a system parameter using the ultrasound system and comparing the determined value to a defined value for a system processing guideline using a processor of the ultrasound system. The method further includes providing system parameter confirmation information based on the comparing when the determined value is not within the defined value.
US08636661B2
An embeddable module for measuring a blood glucose level may be embedded in an external host and may comprise a host interface, a microcontroller, an ASIC, a temperature measuring element, and a measurement strip port. The host interface may permit electrical communication between the host and the microcontroller. The microcontroller and ASIC may communicate with each other and may work together to measure the blood glucose level of a blood sample. The measurement strip port may receive a removable measurement strip having the blood sample. The ASIC may communicate with the measurement strip port such that the ASIC may receive signals from the measurement strip port related to the blood glucose level of the blood sample. The temperature measuring element may be in electrical communication with the microcontroller and may measure the temperature of the module and transmit signals to the microcontroller related to the temperature of the module.
US08636659B2
A multifunctional invasive cardiovascular diagnostic measurement host is disclosed that interfaces a variety of sensor devices, such as guide wire-mounted pressure sensors, flow sensors, temperature sensors, etc, and provides a multi-mode graphical user interface providing a plurality of displays in accordance with the various types of sensors and measurements rendered by the sensors.
US08636654B2
Tissue retraction devices and methods include a tissue retractor with a radiolucent portion to permit imaging through the radiolucent portion with X-ray, fluoroscopic or other suitable imaging system. The tissue retractor also includes one or more radio-opaque elements that define at least a portion of a perimeter of the radiolucent portion to provide an indication of the retractor location in the patient via the imaging system.
US08636647B2
Described herein are delivery devices and methods of using the devices for delivering an ocular implant into a suprachoroidal space without use of a goniolens. The delivery device includes a handle including a channel extending from a proximal end of the handle to a distal end of the handle, an applier coupled to the handle, the applier including a blunt distal tip and an elongate, flexible wire insertable through a fluid channel of an ocular implant, and a fiber optic image bundle reversibly inserted through the channel such that the fiber optic image bundle extends to a region proximal to the blunt distal tip of the applier.
US08636646B2
A penile prosthetic assembly includes a penile implant containing a dilatant liquid and a reservoir connectable with the penile implant. Fluid transferred from the reservoir into the penile implant imposes a shear on the dilatant liquid to increase viscosity in the dilatant liquid and harden the penile implant.
US08636644B2
An incontinence treatment device includes a urethral support and first and second connectors. The urethral support extends between a first end and a second end and has porosity that is configured to allow tissue in-growth through the urethral support. The first connector is attached to the first end of the urethral support and the second connector is attached to the second end of the urethral support. At least one of the first connector and the second connector is a cross-linked polymer connector having a glass transition temperature between 40-70 degrees Celsius. The cross-linked polymer connector has an initial length that is elongated to an implant length that is greater than the initial length. Means for heating the cross-linked polymer connector from an extracorporeal location through intact skin is provided, thereby shortening the cross-linked polymer connector.
US08636635B2
An applicator for delivering brachytherapy includes elongate members movable between collapsed and expanded configurations for delivering brachytherapy within a lumpectomy cavity, a vaginal cavity, or other target region. The elongate members may be expandable into a symmetrical or asymmetrical expanded configuration, e.g., into a generally spherical, pear-shaped, or planar configuration. A system for delivering brachytherapy includes the applicator and an access device for lining and/or dilating a body cavity and/or for receiving the applicator therein. The access device is advanced into a body cavity, an expandable member on the access device is inflated, the applicator is advanced into the access device, and the elongate members are expanded to deliver radiation to the target region. Alternatively, the access device carries an expandable device into the target region, the expandable device is removed after dilating the target region, and the applicator is introduced through the access device to deliver radiation.
US08636632B2
The sleeve roll according to the present invention has the metallic sleeve 5 fitted over the rubber roll 4, covering the surface of the shaft core part 2, and can be efficiently heated or cooled by having the passage P formed between the metallic roll inner tube 2a and the metallic roll outer tube 2b for the thermal medium to flow through. It also has the heat conductive material 6 mixed into the rubber roll 4, so that it has excellent heat conductivity and the surface of the sleeve can be quickly and efficiently heated or cooled, thus preventing the material to be formed from sticking to the roll.
US08636627B2
Anterior cruciate ligament (ACL) is the most commonly injured knee ligament in sports-related activities, especially in pivoting sports. Considering that the knee is free to flex/extend but has much more limited motions about the off-axes (tibial rotation and valgus/varus), ACL injuries are often associated with excessive off-axis loadings. A pivoting/sliding mechanism combined with sagittal plane movement/exercise is described as a diagnostic tool to evaluate off-axis neuromechanical and anatomical risk factors of noncontact ACL injuries. The pivoting/sliding mechanism is also described as an intervention tool for off-axis training, possibly based on the diagnosis, to reduce the incidence of ACL injuries. Training outcome can also be evaluated using the pivoting/sliding mechanism. In general, the pivoting/sliding mechanism can be used with many sagittal plane exercise machines and used to improve off-axis control of the lower limbs and reduce lower limb injuries.
US08636602B2
A bowling lane with a mural image is disclosed. In one embodiment, a plurality of bowling lane panels are provided, wherein each bowling lane panel depicts a different portion of a mural image. The plurality of bowling lane panels are assembled and secured onto a surface such that the assembly of the plurality of bowling lane panels forms the mural image. In another embodiment, a bowling center is provided with at least two bowling lanes. Each bowling lane depicts a mural image, and the mural images on the various bowling lanes form a composite multi-lane mural image.
US08636592B2
Provided are technologies for the distribution of signals corresponding to players in a multi-player game situation to be distributed of appropriate video displays. Frames of a video signal are mapped to corresponding game controllers and the game controllers are mapped to display devices. Frames are then routed to an appropriate video display on a corresponding display device.
US08636591B1
One aspect of the disclosure relates to facilitating virtual item rewards for implementation in a virtual space based on a game of chance in an online game. A virtual wheel with multiple game outcomes may be spun and/or any other action may be taken. One of multiple virtual outcomes corresponding to different game outcomes may be selected and/or displayed. There may be various visual mechanisms for selecting and/or presenting one outcome from multiple possible game outcomes.
US08636583B2
An embodiment of a gaming device includes a game having at least three choices, wherein each of the choices either trumps or is trumped by one of the other choices, and a processor programmed to determine if an outcome enhancing condition is satisfied, enable a player to elect to enhance an outcome if an outcome enhancing condition is satisfied, enable the player to select one of said choices, select one of said choices, determine an outcome based on a comparison of the player's choice with the processor's choice, provide a win outcome if the player elected to enhance an outcome and the comparison of the player's choice with the processor's choice results in a draw determination, provide a draw outcome if the player elected to enhance an outcome and the comparison of the player's choice with the processor's choice results in a lose determination.
US08636574B2
A method provides a player tracking system and system gaming apparatus for playing non-base games by funding the credit side of a gaming cycle. The system further includes at least one gaming device having a base game. The player tracking system and system gaming apparatus includes a player tracking user interface. The player tracking user interface provides a player with an opportunity to select and play a non-base game that may be promotional-funded or player-funded.
US08636573B2
One embodiment of the present invention comprises a method including steps of populating a primary set of card positions with a first set of initial cards, determining at least one discarded card from the first set of initial cards, replacing the at least one discarded card from the first set of initial cards with replacement cards to form a final set of cards, and determining whether to include the at least one discarded card in at least one secondary set of card positions. If the at least one discarded card is to be included in the at least one secondary set of card positions, the method further provides for populating the at least one secondary set of card positions with the at least one discarded card. Some embodiments of the present invention also provide for determining a payout based on at least the final set of cards.
US08636572B2
The invention provides displaying, in a lane, a section of repeatable inputs in a sub-lane of the lane. Cue data is loaded from a data file, which includes duration data and a plurality of cues to be displayed in the sub-lane. Then, the plurality of cues and a section indicator are displayed in the sub-lane, with the section indicator based on the duration data and indicating that the plurality of cues are repeatable inputs. Then, a timer is started that is independent of a timing window of any cue of the plurality of cues. Then, it is determined if an input is received for the sub-lane before the timer reaches a timing threshold. If it is, the timer is restarted and the plurality of cues is maintained as repeatable inputs. If it is not, the section indicator is modified to indicate that the plurality of cues are not repeatable inputs.
US08636563B2
In a rotating grinding- or cutting tool, in particular a grinding wheel or grinding roller, on one body, a coating of abrasive material, e.g. cubic boron nitride (CBN) or diamond is applied. The body (2, 12, 22, 32, 42) has two side walls (2a, 12a, 22a, 32a, 42a; 2a, 12a, 22a, 32a, 42a) which are connected to each other on their peripheral region, with the side walls being constructed with fiber-reinforced composite, in particular carbon fiber-, glass fiber- or synthetic fiber-reinforced composite.
US08636556B2
Apparatus and methods for resizing COTS AMLCDs or other electronic displays, as well as resized displays made using these apparatus and methods, are provided. The electronic display includes a front plate, a back plate, a perimeter seal spacing the front and back plates apart, and image-generating medium contained in an area between the front and back plates. A target portion of the display may be identified and separated from an excess portion of the display, e.g., by cutting and breaking the plates of the display, thereby creating an exposed edge along the target portion. The plates of the target portion are pressed towards one another, e.g., to stabilize or compress the target portion. An adhesive is applied to the exposed edge, and the pressure is released to draw the adhesive between the plates along the exposed edge.
US08636553B1
An assembly (10) is provided for mounting a hydrofoil, trolling plate or trolling motor (or other accessory) on the anti-ventilation plate (14) of a sterndrive or outboard motor (16) without the need to modify the plate or motor. The assembly (10) has lower and upper elements (20, 22) which are secured about the plate (14) by bolts (34). The upper element (22) has a bolt pattern (40) to mount the hydrofoil or other device. A catch (60, 88, 88a, 88b, 88c, 88d) mounted on the lower element (20) can be engaged in the trim tab or anode recess. Grip devices (50) can be mounted on the lower element (20) that are adjusted to grip the edges of the plate (14).
US08636549B2
The present invention relates generally to multi-trace electrical connectors for harsh environments. More particularly, the present invention relates to bayonet rotary electrical connectors which maintain electrical connection dynamically, and which may have replaceable connector components. This type of connector is used, for example, in drilling operations where the connector must be rotated, for example during assembly, disassembly, or operation of bottom hole equipment or sensor or communications packages, and where the electrical connection may be maintained.
US08636543B2
A footprint of an electronic assembly formed from conductive pads on a surface of a printed circuit board. One or more vias may connect each pad to a conductive structure within the printed circuit board. The footprint may be such that the vias for the pads are aligned along columns, leaving wide routing channels between the columns. The pads may have different shapes. For example, some of the pads may each have two solder attachment regions that are electrically connected to a ground plane, while other pads may each have one solder attachment region that is electrically connected to a signal trace. The solder attachment regions may be arranged in such a pattern that they align with respective contact tails of a connector assembly. A signal path may be formed between a solder attachment region and a corresponding contact tail through a solder ball attached to the contact tail.
US08636542B2
Coaxial connector comprising a signal contact member having a connecting terminal portion and a contacting terminal portion, a grounding contact member having an annular engaging portion for engaging with an outer contact member of a mating coaxial connector and a shell portion extending from the annular engaging portion to be connected with an outer conductor of a coaxial cable, and a housing for supporting the signal contact member and the grounding contact member. The connecting terminal portion of the signal contact member is positioned at the outside of the annular engaging portion of the grounding contact member to be connected with a core conductor of the coaxial cable and the contacting terminal portion of the signal contact member is positioned at the inside of the annular engaging portion of the grounding contact member for coming into contact with a central contact member of the mating coaxial connector.
US08636540B2
An electrical connector (100) comprising a housing (200) defining a front face and a first mating cavity recessed rearward from the front face for receiving a modular plug, an electronic module (400) mounted to the housing, a horizontal PCB (500) mounted under the electronic module, and an outer shell (700) shielding the electronic module and the housing. The electronic module has a vertical PCB(420) which includes a ground trace (421) joined to a conductor (427) that extends through a plated hole in the vertical PCB and that is connected to a conductive pin (722) of the outer shell through a conductive trace (56) of the horizontal PCB (500).
US08636535B1
An electrical connector for electrically connecting a central processing unit (CPU) to a printed circuit board (PCB) includes a base having a first opening and a plurality of passageways with a plurality of contacts therein. A base shield is assembled on the first opening of the base. A cover is mounted upon the base and has a second opening corresponding to the first opening of the base and a plurality of through holes corresponding to the passageways. A cover shield is assembled on the second opening of the cover for contacting with the CPU and the base shield. An actuator driving the cover with the cover shield slides along the base with the base shield in a front-to-back direction.
US08636532B2
In a gas sensor, when an arithmetical mean roughness Ra of an inner periphery of a metal tube 95 is 1 μm or less and end portions 93 and 94 of U-springs 92 are formed as curved contact portions, the end portions 93 and 94 of the U-springs 92 can slide smoothly along the inner periphery of the metal tube 95. Therefore, when vibration is applied to the gas sensor, the U-springs 92 can be prevented from being caught in the inner periphery of the metal tube 95, and the vibration can be absorbed by an elastic function of the U-springs 92. Even if the gas sensor vibrates, defective contact between a sensor element 20 and contact fittings 71 and wear and cracks in the sensor element 20 are less likely to occur. That is, the gas sensor resistant to vibration can be obtained.
US08636528B2
A memory module connector includes a dynamically-assisted latch that facilitates connecting and releasing a memory module. The latch includes a lever pivotably coupled to the connector for urging the memory module into and out of a fully seated position within the connector. The lever provides a mechanical advantage for lowering and raising the memory module. A latch assist member urges the latch into engagement with the memory module in response to an insertion of the memory module, and dynamically positions the lever in response to movement of the memory module within the connector.
US08636527B2
An electrical connection assembly includes a female element having at least one electrical contact and a male element to be inserted in the female element and which includes a plug and a sleeve that surrounds and is movable relative to the plug and at least one electrical contact is carried by the plug and is electrically engageable to the electrical contact of the female element. An external surface of the sleeve has at least two stages with diameters which are smaller in a direction toward a free end of the male element and the female element has a body with an internal surface having at least two stages with diameters which are larger in a direction toward a mouth of the female element and such that the at least two stages of the external and internal surfaces seat with one another when the male element is inserted into the female element.
US08636526B2
Circuits, methods, and apparatus that provide connector receptacles having a smaller size. One example provides this smaller size by decreasing the depth of the connector receptacle. Contacts in the connector receptacle may be protected from damage due to improper insertion of a second electronic device or connection to a second electronic device. This protection may be achieved in various ways. In some examples, one or more components or one or more contacts may be used to block the improper insertion of a second electronic device or connection to a second electronic device. In other examples, one or more contacts may avoid damage by being located outside of an insertion path until a second electronic device or connection to a second electronic device is inserted. In other examples, instead of blocking or avoiding an improper insertion, the contacts may avoid damage by bending out of the way.
US08636525B2
According to embodiments of the disclosure there is provided an apparatus including a user input device; and a mechanism configured to enable the user input device to be moved between a first position and a second position wherein when the user input device is in the first position a socket is accessible by a user of the apparatus and when the user input device is in the second position the socket is not accessible by the user of the apparatus.
US08636519B2
Apparatus, including: a mockup probe, having a distal end and a proximal end adapted to be held by a human operator. The apparatus further includes a mockup patient, simulating an actual patient, the mockup patient having an aperture allowing penetration of the distal end of the mockup probe into the mockup patient. The apparatus includes a force generator, coupled to the mockup probe so as to apply a force to the proximal end that can be felt by the human operator, and a system controller. The controller is configured to: track a location of the distal end during the penetration thereof into the mockup patient, access an indication of a value of contractility of a region of an organ of the actual patient corresponding to the location, and activate the force generator so that the force applied to the proximal end corresponds to the indication.
US08636513B2
Systems and methods produce a physical base for receiving physical tooth models by receiving position information for the physical tooth models on the physical base and machining first features on a base plate in accordance with the position information to produce the physical base, wherein the first features are configured to receive the physical tooth models.
US08636506B2
An improved vibrating dental plate that allows differential vibration of one or more teeth to assist in orthodontic remodeling is provided.
US08636499B2
The equipment consists of a mould (1) with external heating elements (3) and with asymmetric heads (4) at the ends thereof, allowing insertion of the corresponding tubular profile or plastic tube (6) inside the already hot mould (1) at the same temperature as the actual mould (1) in order to prevent any heat exchange. The mould (1) is mounted on a support (2) that can tilt and rotate, while the heads (4) include a vacuum take-off orifice (5), fastening means (7) for the plastic tube (6), which, once inserted into the mould (1) rests on the lower generatrix of the latter, and inlet (8) and outlet (9) means for fluids for expanding the plastic tube (6) and for cooling same, the mould (1) incorporating, on the side, an inlet orifice for a lubricating fluid that facilitates removal of the plastic tube (1) once the latter has been shaped. The tube (6) expands owing to the introduction of the expander fluid through the inlet (8).
US08636496B2
Systems and methods for fabricating three-dimensional objects. The system includes an optical imaging system providing a light source; a photosensitive medium adapted to change states upon exposure to a portion of the light source from the optical imaging system; a control system for controlling movement of the optical imaging system, wherein the optical imaging system moves continuously above the photosensitive medium. The method includes moving a maskless optical imaging system providing the light beam in a continuous sequence; presenting the light beam on a portion of the photosensitive medium; lowering a plate upon which the photosensitive medium resides; and applying a new layer of the photosensitive medium.
US08636492B2
The methods and apparatuses for granulating thermoplastic material emerging from nozzles in a perforated plate are provided. The apparatus can have a motor-driven cutter arrangement having at least one blade located opposite the perforated plate. The at least one blade can pass over the nozzles in the perforated plate and cuts pellets of the emerging thermoplastic material.
US08636491B2
The tire vulcanizer is featured by including a slide back mechanism configured such that the upper metal mold separated and lifted from the lower metal mold installed to be fixed to a base is moved by an operation of a movable carriage so as to reciprocate between a vulcanization position at which the upper metal mold is pressed toward the lower metal mold, and a waiting position at which the green tire can be carried in the lower metal mold and at which the cured tire can be carried out from the lower metal mold, and is featured in that the upper metal mold is attached below, via a squeezing cylinder mechanism, to a beam integrated with a tie rod which is vertically moved by an operation of a lifting/lowering cylinder along a guide hole provided in the movable carriage.
US08636489B2
An apparatus for the shaping of plastics-material containers with a blow mold, wherein the blow mold has at least one first and one second blow-mold part, may include at least one first and one second carrier element for holding the blow-mold parts. The carrier elements are movable relative to one another at least in one plane, in order to be transferred at least from a closed configuration into an opened configuration. In this case the carrier elements each have a receiving area for receiving one blow-mold part in each case, wherein the blow-mold parts in the closed configuration form at least one cavity for the expansion of the containers. The blow-mold parts may be capable of being coupled in a magnetic and releasable manner to each other and/or at least one of the blow-mold parts is capable of being coupled in a magnetic and releasable manner to at least one carrier element.
US08636482B2
A submersible turbine pump (STP) comprising a manifold, a yoke assembly including a yoke sleeve integrally connected to the manifold, and a packer removably secured to the manifold is provided. The manifold includes an electrical cavity that receives electrical wiring from an external source. The yoke sleeve has a hollow interior and is integrally connected to manifold, and a first end of the yoke sleeve is within the electrical cavity. The packer includes a chamber having a yoke sleeve inlet port and an electrical conduit inlet port. The yoke sleeve inlet port receives a second end of the yoke sleeve extending from the manifold, and the electrical conduit inlet port receives an electrical conduit extending from a pump within an underground storage tank. The electrical wiring passes from the electrical cavity to the chamber through the yoke sleeve and then to the pump through the electrical conduit.
US08636463B2
Cooling channels through the interior of a machine component that include: a first set of cooling channels, the first set of cooling channels including a plurality of parallel channels that reside in a first plane; a second set of cooling channels, the second set of cooling channels including a plurality of parallel channels that reside in a second plane. Along a longitudinal axis, the cooling channels of the first and second set of cooling channels may include an alternating diverging-converging configuration, the alternating diverging-converging configuration creating a series of broader chamber sections connected by a series of narrower throat sections. The first set of cooling channels and the second set of cooling channels may be configured such that, when viewed from the side, a crisscrossing pattern with a plurality of intersections is formed. The first plane resides in spaced relation to the second plane, with the first plane being offset from the second plane such that a plurality of the chamber sections of the first set of cooling channels connect to a plurality of the chamber sections of the second set of cooling channels.
US08636457B2
A two-way fastener includes a first member configured to be attached to a first workpiece via a tool selected from the group consisting of: a pair of pliers, a screwdriver, a nutdriver and a hammer; and a second member configured to be attached to a second workpiece such that the second workpiece comes together with the first workpiece and at least substantially hides the entire two-way fastener, the second member extending in an opposite direction as the first member.
US08636456B2
A building structure including a first building member and a second building member may be connected by fasteners, each fastener having a head, a tapered lead portion having an angle from 30 to 60° of at least HRC 50 hardness adapted to start into a pilot hole, a thread-forming portion of at least HRC 50 hardness adapted to thread the fastener into at least the second steel building member, and a threaded portion having a through hardness from about HRB 70 to HRC 40, such that the fastener is capable of providing a ratio of failure torque to thread-forming torque of at least 3.0 and a ratio of failure torque to drive torque greater than 10 when the second steel building member has a thickness of about 0.25 inch and the pilot hole has at least one diameter within nominal diameter from 80 to 98% of major diameter.
US08636455B2
A fastener assembly is installable in an opening of a workpiece and includes an outer member and a fastener. The fastener is movable through a passageway of the outer member. The fastener includes a mandrel and a stem. The mandrel is dimensioned to radially expand the outer member. The stem has an expansion portion and a propping portion. The expansion portion radially expands the outer member after the outer member has been expanded by the mandrel. The propping portion keeps the expanded outer member in an installed expanded configuration. The outer member and fastener are installed in a single operation to reduce installation time.
US08636450B2
In a tie down system and method for securing a vehicle tire to a wire grate, a slotted overlay panel rest on top of the wire grate. A clevis assembly having one end of a tire trap assembly attached thereto is provided along with the winch assembly having a winch for receiving an opposite end of the tire strap assembly. Each of the clevis assembly and winch assembly have a T hook with a T portion which is insertable through a respective slot of the overlay panel.
US08636438B2
The invention relates to a device for fastening at least one component of an exhaust system to at least one member of a motor vehicle, including a component leg that is designed for rigid fastening to the at least one component of the exhaust system and one member leg that is designed for rigid fastening to the at least one member of the motor vehicle. A coupling body with or made of an elastomer is provided, the coupling body being connected on the one hand fixedly to the component leg and on the other hand being fixedly connected to the member leg.
US08636437B2
A corner member for a window screen for joining framing members together at the corners, the corner member having a central body, first and second legs extending outwardly therefrom, a recess formed in the central body portion, and a plurality of resilient retaining members placed in the recess, each resilient retaining member having first and second retaining tabs which extend outwardly and which are designed to retain the screen in the window frame.
US08636435B2
A dispensing system for spreadable foodstuffs and spreadable non-food substances allowing for dispensing of metered amounts of product and spreading without the need for additional utensils not part of the packaging is disclosed. The system is composed of a disposable container containing a spreadable food stuff or non-food substance. The container comprises a mechanism for dispensing said foodstuff or non-food substances while proportionally decreasing the volume of the container. An alternative embodiment discloses a disposable dispenser allowing for spreading foodstuffs or non-food substances without any additional utensils in an ultra-portable unit without mechanical components.
US08636428B2
An imaging apparatus includes a diaphragm configured to control an amount of incident light, a variable transmittance and reflectance element configured to reflect a part of the incident light to an optical viewfinder and transmit the remainder of the incident light as imaging light, and a controller configured to increase reflectance of the variable transmittance and reflectance element as a setting value of the diaphragm increases.
US08636425B2
A connector includes a ferrule assembly having a ferrule, a hub and a spring, the ferrule having a distal face accessible at a distal end of the connector housing, the ferrule being movable in a proximal direction relative to the connector housing. The distal and proximal positions are separated by an axial displacement distance. The ferrule proximal movement is against the spring's bias. The cable of the assembly includes an optical fiber contained within a jacket and also a strength layer between the fiber and the jacket that is anchored to the connector housing. The fiber extends through a fiber passage from the proximal end of the connector housing to the ferrule. The fiber has a distal portion potted within the ferrule. The fiber passage has a fiber take-up region configured to take-up an excess length of the fiber corresponding to the ferrule axial displacement.
US08636414B1
A bearing assembly for an oscillation joint on a machine having a tandem wheel drive. The bearing assembly rotatably supports an oscillating hub rotatably connected to a shaft. The bearing assembly includes a frustoconical inboard bearing having a first bearing surface and a frustoconical outboard bearing having a second bearing surface disposed thereon positioned such that the first and second bearing surfaces form a generally v-shaped bearing interface between the shaft and the hub.
US08636408B2
A temperature measurement system includes: a laser light source; an optical fiber; and a temperature measurement unit configured to acquire a measured temperature distribution of a temperature of a temperature measurement area along an installation path of the optical fiber by detecting backscattered light of the incident laser light in the optical fiber, wherein the temperature measurement unit sequentially makes a correction for the measured temperature distribution a plurality of times so as to make a square error between a convolution of a transfer function of the optical fiber along the installation path and the corrected temperature distribution and the measured temperature distribution smaller in each of the corrections, and the temperature measurement unit also replaces a corrected temperature at a specific point of the installation path with an estimated temperature at the specific point in each of the corrections.
US08636397B2
There is presented a vehicle headlamp with an imaging optics that is designed to project, as light/dark boundary, into the area in front of the vehicle headlamp, an edge that delimits a light flux of a light source of the vehicle headlamp, a boundary surface of a component of the imaging optics, through which the light flux penetrates, having an overhead element in the form of a local deformation of the boundary surface having a prismatic effect by means of which the light is deflected into an overhead area lying over the light/dark boundary. The vehicle headlamp is distinguished by the fact that the boundary surface has more than one hundred overhead elements distributed discretely over the boundary surface.
US08636392B2
A method for controlling a light emission of at least one headlight of a vehicle. The method includes receiving a change enabling signal for performing a change of the light emission of the at least one headlight from an input emission characteristic to an output emission characteristic during a debouncing period and/or debouncing distance which begin(s) in response to the change enabling signal. The method also includes changing the light emission of the at least one headlight from the input emission characteristic to an intermediate emission characteristic in response to the change enabling signal. The method also includes changing the light emission of the at least one headlight from the intermediate emission characteristic to the output emission characteristic after the debouncing period and/or the debouncing distance has/have elapsed.
US08636382B2
A light source apparatus, an image display apparatus and a television receiving apparatus are provided, which can electrically connect boards with each other even if the boards are separated from each other by more than or less than a predetermined distance. In a light source unit in which plural LEDs are aligned on one surface of a LED board 2, plural stoppers 20 are arranged at another surface 2b of LED board 2 to stop the stopper 20 at stop slits 63, 63, . . . 63 of a support member 6 which is to hold the light source unit, and to hold the light source unit to be slidable along one surface of the support member 6.
US08636377B2
A light tube holder includes a base and two connectors for receiving either a light-emitting diode (LED) tube or a fluorescent tube. The connector includes a rotary member rotatably received in a through hole defined in a retainer, and three conductive elastic pieces positioned in the retainer around the through hole. One elastic piece is electrically connected to an LED tube drive circuit board, and the other two elastic piece are electrically connected to a fluorescent tube drive circuit board. The rotary member can be rotated to first and second positions, wherein at the first position, the LED tube can be activated, and at the second position the fluorescent tube can be activated.
US08636368B2
A projection display apparatus and an actuation control method thereof are provided. A projection display apparatus includes an apparatus body that forms an optical image projected on a screen, a projection lens that projects the optical image formed by the apparatus body on the screen, a lens actuator that allows the projection lens to be shifted in a vertical direction or in a horizontal direction relative to the apparatus body, and a shift controller that limits a range of shift movement by the lens actuator such that a center position of the projection lens does not go outside of a quadrangle region of which the intersection point of diagonals is located coaxially with the position of the optical axis of the apparatus body.
US08636362B2
An ophthalmic imaging apparatus divides a frame image obtained by capturing a moving image into a plurality of regions grouping pixels, and acquires photometric values corresponding the plurality of the regions. Further, the ophthalmic imaging apparatus determines acknowledgement or dis-acknowledgement of capturing a still image based on temporal variation of the acquired photometric values or distribution of the acquired photometric values on a fundus image. The ophthalmic imaging apparatus inhibits to execute a still image capturing of the fundus if the dis-acknowledgement of capturing is determined.
US08636357B2
A contact lens having one or more fiducial marks that allow the measurement of lens rotation and centration. The lens may be a trial lens. The lenses can be used to apply correction factors for sphero-cylindrical refractive error, higher order aberrations, and corneal topography.
US08636356B2
An eye wear system comprising a frame configured to receive at least one lens, with stems pivotably coupled to the frame, wherein stems have a first portion and a second portion, and a first, i.e. open, orientation disposed generally perpendicular to the frame, and a second, i.e. collapsed, orientation disposed generally parallel to the frame. The nose pads, which can be integrally formed with the frame, form at least part of an opening configured to receive the first portion of the stem to releasably secure the stem in the second, or collapsed, orientation.
US08636355B2
A target supporting apparatus includes a first supporting member having a plurality of first suction holes open to the front surface of the member and the rear surface thereof; a second supporting member having a plurality of second suction holes formed therein and being stacked on and fixed to the first supporting member, the cross-sectional area of each of the plurality of second suction holes being smaller than the cross-sectional area of each of the plurality of first suction holes; and a sucking unit that sucks in the plurality of first suction holes and hence sucks in the plurality of second suction holes communicating with the plurality of first suction holes. Here, a target which is supported in order for a liquid to be adhered thereto is sucked and held onto a supporting face of the second supporting member due to the driving of the sucking unit.
US08636354B2
A liquid ejecting apparatus includes: a head that ejects liquid to be cured by receiving irradiation of an electromagnetic wave onto a medium; a provisional-curing irradiation section that emits a first electromagnetic wave to a dot formed on the medium by the liquid; and a main-curing irradiation section that emits a second electromagnetic wave, which has irradiation intensity higher than that of the first electromagnetic wave, to the dot to which the first electromagnetic wave is emitted. When the main-curing irradiation section emits the second electromagnetic wave, a dot forming surface of the medium faces the lower side in the direction of gravity.
US08636349B2
A continuous liquid ejection head collects droplets which are not used for printing (unused droplets) without affecting the flight of droplets which are used for printing (used droplets). An ejection nozzle and a collection nozzle collect an unused droplet by causing a liquid surface to project out from the aperture of the collection nozzle so as to be positioned in the trajectory along which droplets ejected from the ejection nozzle fly, causing the unused droplet to collide and unite with the liquid surface projected from the collection nozzle, and causing the liquid surface to retreat.
US08636332B2
The image recording apparatus includes: a recording head in which a plurality of recording elements are arranged over a length corresponding to a recordable width of a recording medium; a conveyance device which performs conveyance to cause the recording head and the recording medium to move relatively to each other one time only in a conveyance direction, a reference line being arranged on the conveyance device; an image output device which records a prescribed image on the recording medium through the recording head; a sensor which reads the reference line on the conveyance device, and reads the prescribed image on the recording medium recorded by the image output device; and a displacement evaluation device which evaluates a displacement between the reference line and the recording head in accordance with a result of reading the reference line by the sensor and a result of reading the prescribed image by the sensor.
US08636326B2
A track frame is swingably supported by a rear axle case of a travel machine body through a rocking shaft; front and rear driven wheels are disposed in front and rear end portions of the track frame; at least three idling wheels are disposed on an intermediate portion of the track frame at intervals in a longitudinal direction; a drive wheel which is disposed upward of a longitudinal intermediate portion of the track frame and is configured to receive a power transmitted from a rear axle supported by the rear axle case; and a crawler belt is wrapped around the drive wheel, the front driven wheel, the rear driven wheel and the idling wheels. Two idling wheels on a rear side of the at least three idling wheels are pivoted on a first rocking link, and a longitudinal intermediate portion of the first rocking link is pivoted on the track frame through a first pivot shaft.
US08636320B1
A system of controlling various actuators associated with human support surfaces is disclosed. Such a system is made up of a support surface, a controller, and an actuator. The system may optionally include batteries, a means of charging the batteries, and a graphical user interface as well as a communication link between the graphical user interface and the support surfaces. The actuators are capable of altering contour and/or firmness, of a support surface, they may be vibrational or heating/cooling in nature, and they may also alter the overall relative position of a support surface.
US08636315B2
A roller blind arrangement, in particular for a vehicle, with a roller blind web. The roller blind web can be wound up at least at one end by a winding device to form a roller blind winding having a geometrical center axis. The roller blind web can be unwound in an unwinding direction. The winding device has a guide element arranged with respect to the geometrical center axis of the roller blind winding in a direction essentially opposite to the unwinding direction and is designed to limit a movement of the roller blind winding in the direction opposite to the unwinding direction. The invention also relates to a roof arrangement with a roof opening, a roof opening frame that bounds the roof opening, and a roller blind arrangement. The roller blind arrangement is arranged in the roof opening and is mechanically coupled to the roof opening frame.
US08636292B2
A spring suspension assembly (50, 50A) for a vehicle which has a plurality of spring elements (77, 83, 77A, 77B, 77C, 83A, 83B, 83C, 787E, 88F, 77G, 77H, 77I, 116, 117, 132, 133, 141, 142) which are attached to an inner carrier (56, 117A) and an outer carrier (86, 120) wherein respective arrays (76, 82, 76A, 76B, 82A, 82B) are oriented in opposing or counteracting orientation and each spring elements (77, 83, 77A, 77B, 77C, 83A, 83B, 83C, 787E, 88F, 77G, 77H, 77I, 116, 117, 132, 133, 141, 142) has a shape corresponding to an arc of a circle characterized in that outer carrier (86, 120) is adapted to be mounted to a vehicle chassis and the inner carrier (56, 117A) is mountable to a vehicle axle shaft.
US08636290B2
A tool cart assembly including a tool cart having a horizontal surface defining a mounting aperture, a first rail including a bottom wall, a pair of opposed sidewalls, a front edge of each sidewall defining a catch, and at least one projection depending downwardly from the bottom wall, the projection being configured to be received in the mounting aperture such that the first rail is secured to the horizontal surface. A tool kit includes a sidewall and a first elongated rib, the elongated rib is configured to be slidably received by the first rail. The tool kit is removably secured to the tool cart by positioning the elongated first rib in the first rail and sliding the tool kit rearwardly such that the catches defined by the first rail engage a first portion of the tool kit.
US08636286B2
A face seal comprises a first half and a second half. Each half of the face seal comprises an inner sealing ring, the inner sealing ring being generally L-shaped in cross-section, an elastomer ring disposed over the inner sealing ring, and an outer ring disposed over the elastomeric ring, the outer ring being generally Z-shaped in cross-section. The inner sealing ring comprises an axially extending circular cylindrical portion, a radially extending planar ring portion coupled to the cylindrical portion, and a sealing surface defined by the seal side planar wall. The outer ring comprises an axially extending second circular cylindrical portion, a seating flange extending radially outward from a front end of the second cylindrical portion, and a backing flange extending radially inward from the rear end of the second cylindrical portion.
US08636270B2
A low cost, flexible, torqueable structure for use as at least a portion of a medical device comprises a coil formed of a wound element. The coil includes a plurality of adjacent windings. Connected portions of a region between the adjacent windings are formed (by, for example, laser welding) such that torque can be transmitted between adjacent windings.
US08636267B1
A plurality of atomizing fans are mounted on a portable land craft. A pump delivers pond water to the land craft to evaporate the pond water. A land based generator powers the pump and the atomizing fans. The entire system could be mounted on a single trailer.
US08636257B2
A support and cushioning device for supporting and holding an electronic device includes a first supporting assembly, a fixed bracket, an adjusting board, and a plurality of elastic members. The adjusting board is mounted to the distal end of the first support assembly. The fixed bracket is elastically mounted to the adjusting board by means of a plurality of elastic members. The fixed bracket includes a base body and a plurality of holding arms extending out from a periphery of the base body. The plurality of holding arms and the base body cooperatively define a holding space for holding an electronic device.
US08636247B2
A gas generator assembly includes a propellant chamber housing an amine based propellant. A reaction chamber is coupled with the propellant chamber. The reaction chamber includes a reaction chamber housing, and a porous reaction matrix within the reaction chamber housing. The reaction matrix includes a catalyzing agent, and the catalyzing agent is configured to non-combustibly catalyze the amine based propellant into one or more pressurized gases. An injector is in communication with the propellant chamber. The injector is configured to deliver the amine based propellant to the porous reaction matrix. A discharge nozzle is coupled with the reaction chamber and is configured to accelerate and discharge the one or more pressurized gases. In one example, the gas generator is coupled with one or more of an impulse turbine assembly and an electric generator to form a micro power unit.
US08636245B2
An aircraft having at least one in-flight attitude control system, in turn having at least one actuator; and a hydraulic circuit connected to the actuator and having at least one pump designed to deliver a first flow when the pressure of the hydraulic circuit is above a presettable threshold value. The pump is designed to deliver a second flow greater than the first flow, and the aircraft has a sensor for detecting a quantity associated with the pressure of the hydraulic circuit; and a programmable central control unit, which controls the pump to deliver the second flow when the quantity detected by the sensor corresponds to a pressure of the hydraulic circuit below the threshold value.
US08636239B2
The invention relates to a belt retractor for winding up and unwinding a safety belt, with at least one force transmission element which is held by a first part of the belt retractor and which can be connected to a second part of the belt retractor, the force transmission element being held in a recess of the first part in such a way that it can be pressed axially into the recess of the first part, with the result that the connection to the second part is broken.
US08636232B2
A method for spraying a medium mist, particularly a medium mist used in firefighting, over a large area. In the method, at least two sprays of medium mist are formed, of which a first spray is within a second medium mist spray at least at or near the spraying point. During the formation of the sprays, the medium is set into a swirling motion at least before the discharge opening of the nozzle used to form each spray and/or at least before the sprays are mixed with each other. The swirling directions of the medium in different sprays are opposite to each other, whereby a preferably homogeneous mist spray spread over a large area is achieved.
US08636224B2
There is described a system and method for automatically discriminating between different types of data with an image reader. In brief overview of one embodiment, the automatic discrimination feature of the present image reader allows a human operator to aim a hand held image reader at a target that can contain a dataform and actuate the image reader. An autodiscrimination module in the image reader in one embodiment analyzes image data representative of the target and determines a type of data represented in the image data.
US08636214B2
Systems and methods for recognition of encoded information on documents are disclosed. According to an aspect, a system includes a document reader configured to read encoded information from a document, and to output an electrical signal representative of the encoded information. The system also includes signal conditioning modules that are each configured to receive the electrical signal, and to condition the received electrical signal differently for outputting a plurality of conditioned electrical signals. Further, the system includes an information recognition module configured to analyze each of the conditioned electrical signals and to select one of the conditioned electrical signals for use in recognizing the encoded information.
US08636206B2
Aspects and embodiments of the present invention relate to alternative kinds of transactions, which do not involve payment using only cash or a token device such as a smart card or chip and PIN card. In some embodiments, transactions involve a customer providing token-less transaction authentication information using customer interface means (150) that is adapted to receive, from a customer, in a first mode of operation, PIN or other token device authentication information, for use in a token device transaction, and token-less transaction authentication information, when operating in another mode of operation. In some embodiments, the customer interface means may be a specially-adapted chip and PIN card reader apparatus. Accordingly, such a customer input means facilitates manual input by a customer of voucher, coupon, accrued loyalty points, Air Miles, ticket or pass authentication information, without the need for a retailer to install new equipment or IT infrastructure.
US08636202B2
Provided is an apparatus that stores a formulary. The apparatus includes a memory device that stores the formulary, the formulary comprising a plurality of drug entries. A user input device allows a user to verify a drug of the plurality of drug entries of the formulary. A code reader interprets computer-readable codes. After a computer-readable code that is associated with the drug is read by the code reader, the drug is verified using the user input device.
US08636200B2
A method of operating a reader system includes: establishment a hand held reader configured to read an information bearing medium at an establishment and accepting text message communications from the establishment; reading the information bearing medium at the establishment with the reader; and, sending at least one text message communication to an operator of the reader at the establishment on the reader GUI from the establishment when the establishment recognizes a need for a specific notice requirement after reading the information bearing medium.
US08636196B2
A separator with a helix assembly that includes a plurality of segments disposed end to end and forming an intermediate casing. Each of the segments has a tubular portion with a first circumferential edge and a second circumferential edge and a helical portion extending from the second circumferential edge. The tubular portions of the segments form an intermediate casing, while the helical portions of the segments form a spiral helix. The helix assembly further includes an inner casing concentrically disposed within the intermediate casing and coupled to the spiral helix.
US08636193B2
A staple pocket arrangement on the anvil portion of a surgical stapler device includes pairs of staple pockets corresponding to each one of a plurality of staples to be closed. The staple pockets may have a generally triangular shape when viewed from above. Each respective staple leg is received at a longitudinal end of the staple pocket that provides a relatively wide target area for receiving the staple leg to eliminate or at least minimize the likelihood that a staple leg will miss the staple pocket due to, e.g., misalignment between a first jaw of the surgical stapler having the anvil and a second jaw of the surgical stapler having a cartridge configured to fire the staples. The staple pockets may be arranged in rows, each row of staple pockets being longitudinally offset from another row, such that each staple pocket in a first row of staple pockets is nested with a staple pocket from an adjacent row of staple pockets to make more efficient use of space on the anvil.
US08636188B2
This document discloses, among other things, a long reach, side ejecting fastener placement apparatus suitable for use in nasal septal surgery. A first linear member carries a fastener body and a second linear member delivers a fastener retainer or provides support for placement of the fastener body. In various examples, the fastener includes a single stud rivet or includes a two legged staple. A mechanical linkage coupled to the handle provides a linear force for placement and deployment of a fastener.
US08636185B2
A nailer includes a power source including a piston reciprocating within a cylinder, a driver blade secured to the piston for common movement relative to a nosepiece, a magazine connected to the nosepiece for feeding fasteners sequentially for being driven into a workpiece by the driver blade, a delay mechanism operatively associated with the magazine and configured for engaging a second fastener and delaying advancement of the subsequent fastener to the nosepiece until the driver blade returns to the pre-firing position after driving a leading fastener.
US08636182B1
A device for movably mounting a storage container in relation to the storage bed of a pickup truck. The device includes a container support frame with a mounting member configured to be fixedly secured in relation to the pickup truck storage bed, and a lift arm having a first end coupled to the container support frame for pivotal movement about a first pivot axis and a second end configured to be coupled to the storage container for pivotal movement about a second pivot axis. The second end of the lift arm is movable along an arcuate path about the first pivot axis between a stowed position in which the storage container is disposed between the side rails and an extended position in which the storage container is disposed above a side rail. The storage container is pivotable about the second pivot axis to maintain an upright orientation in the stowed and extended positions, providing a variety of convenient access and storage options. Also, the frame can be confined to a very small portion of the storage bed or hidden within existing components of the storage bed to allow substantially unimpeded top and rear access to the storage bed.
US08636180B2
A pinch valve for use with a liquid dispensing cabinet is comprised of a tube pinching device configured to translate between an open position and a closed position and an electrically powered linear actuator configured to provide a valve opening force to the tube pinching device, The pinching device is coupled to a spring device configured to apply a valve closing force to the tube pinching device. The pinch valve is additionally comprised of an operator handle facilitating manual opening of the tube pinching device. The pinching device is rotatable in the valve body. The valve body has a front surface heat sink against which a tube pinching force is applied by a tube pinching device and a rear surface with a concavity configured to receive a tube carrying a heat transferring fluid. The tube pinching device can be operated electrically or manually.
US08636172B2
Devices, systems and methods for controlling dispensing of medication are provided. A dispenser device used, for example, in the systems and methods can include a housing for storing units of medication and a dispensing well having an opening therein to permit removal of units of medication therefrom. The dispenser device can include first and second slides having openings therein that are configured to funnel a unit of medication toward the opening in the dispensing well. The opening in the first slide can be configured to funnel a unit of medication to the opening of the second slide upon movement of the first slide, while the second slide can be configured to funnel the unit of medication to the opening in the dispensing well upon movement of the second slide into a position that is aligned with the opening in the dispensing well.
US08636161B2
A two-part closure (1) which has a disc (2) and a skirt (3). In one example, the skirt wall is smooth between upper and lower rims so that the disc is moveable between the rim features. Typically in a metal skirt or ring, the upper rim feature is a curl (11) and the lower rim feature is a curled edge (12) with equi-spaced lugs (13) on the skirt wall.
US08636156B2
A rack for storing objects on a door has at least two uprights, at least two hanging brackets, a plurality of shelf supports, a plurality of shelves and at least two hanging links. The uprights are spaced apart a distance equal to a length of the shelves and spaced from the door by ends of the uprights angled toward the door. The shelves may be disposed at an angle relative to a vertical position of the uprights wherein a superior mounted pair of uprights has hanging links depending from a lower support end and the hanging links are engaged upon an upper support end of another pair of uprights.