发明授权
US08637681B2 Pyrrolyl substituted dihydroindol-2-one derivatives, preparation methods and uses thereof 失效
吡咯基取代的二氢吲哚-2-酮衍生物,其制备方法和用途

Pyrrolyl substituted dihydroindol-2-one derivatives, preparation methods and uses thereof
摘要:
Provided are pyrrolyl substituted dihydroindol-2-one derivatives represented by formula (I), pharmaceutically acceptable salts or solvates of said derivatives, or solvates of said salts, which are effective tyrosine kinase inhibitors. Also provided are the preparation methods of the above compounds, pharmaceutical compositions containing these compounds, and the use of these compounds in manufacturing drugs useful for the treatment or adjunctive treatment of tumors medicated by tyrosine kinases or proliferation or migration of tumor cells driven by tyrosine kinases in mammals (including human).
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