公开(公告)号：US10078071B2

公开(公告)日：2018-09-18

申请号：US14869984

申请日：2015-09-29

申请人： The United States of America, as Represented by the Secretary of Agriculture

发明人： Hans T. Alborn ,  Steven D. Willms

IPC分类号： G01N30/12

CPC分类号： G01N30/12 ,  G01N2030/122

摘要： Herein is described an apparatus for adaptation to existing GC/MS systems, utilizing a splitless injector as the desorption oven with a liquid CO2 cooled low thermal mass cryo trap that eliminates the need for flash heating of volatile compounds.

公开(公告)号：US20160061520A1

公开(公告)日：2016-03-03

申请号：US14828568

申请日：2015-08-18

申请人： Matthias Meilinger

发明人： Matthias Meilinger

IPC分类号： F25J3/04

CPC分类号： F25J3/04412 ,  F25J3/04296 ,  F25J3/04642 ,  F25J3/04654 ,  F25J3/04666 ,  F25J3/04678 ,  F25J3/04709 ,  F25J3/04727 ,  F25J3/04745 ,  F25J3/04751 ,  F25J3/04757 ,  F25J3/0486 ,  F25J2280/02 ,  G01N1/22 ,  G01N1/2247 ,  G01N1/2273 ,  G01N33/0004 ,  G01N33/0006 ,  G01N33/0036 ,  G01N2030/122

摘要： A method for the cryogenic fractionation of air, in which a liquid volume present in a vaporization chamber in a distillation column system of an air fractionation plant is fed by means of a cryogenic liquid and in which a proportion of the liquid volume is continuously transferred into the gas phase by vaporization, wherein, in addition to oxygen, the cryogenic liquid contains components, including xenon, which are higher-boiling than oxygen. The content of xenon in the cryogenic liquid is determined and used as a measure of any enrichment of the components which are higher-boiling than oxygen in the cryogenic liquid. A corresponding air fractionation plant is also described.

摘要翻译： 一种用于空气的低温分馏的方法，其中存在于空气分馏装置的蒸馏塔系统中的蒸发室中的液体体积通过低温液体进料，其中一部分液体体积连续转移到 气相，其中除了氧以外，低温液体含有比氧更高沸点的成分，包括氙。 确定低温液体中的氙的含量，并将其用作在低温液体中沸点高于氧的组分的任何富集的量度。 还描述了相应的空气分馏装置。

公开(公告)号：US06838288B2

公开(公告)日：2005-01-04

申请号：US10070544

申请日：2001-11-28

申请人： Jan Beens

发明人： Jan Beens

IPC分类号： G01N30/54 ,  G01N30/02 ,  G01N30/12 ,  G01N30/30 ,  G01N30/46 ,  G01N30/60 ,  G01N30/62 ,  G01N30/86

CPC分类号： G01N30/465 ,  G01N30/463 ,  G01N2030/025 ,  G01N2030/122 ,  G01N2030/3023 ,  G01N2030/623 ,  Y10T436/204998 ,  Y10T436/25875

摘要： This invention relates to a modulator for use in gas chromatographic analysis, adopted for alternatively trapping and releasing fractions of solutes in a length of a capillary column within a chromatographic oven, characterized in that it comprises at least one nozzle placed to spray at least one jet in at least one corresponding place along said capillary column length, said nozzle(s) being connected each to a source of liquid CO2 via a related valve, and means for alternatively opening said valve(s) for a predetermined time, to cause a jet of liquid CO2 to impinge for said predetermined time on said column place and to leave the oven atmosphere to heat said column place after said predetermined time. The modulator can be used in a conventional GC system or in a two dimensional GC system, for modulating the analytes fed to the second capillary column.

公开(公告)号：US06311544B1

公开(公告)日：2001-11-06

申请号：US09638849

申请日：2000-08-16

申请人： Michel Bertrand

发明人： Michel Bertrand

IPC分类号： B01D1508

CPC分类号： G01N30/463 ,  G01N30/30 ,  G01N30/86 ,  G01N2030/025 ,  G01N2030/122 ,  G01N2030/128 ,  G01N2030/407 ,  G01N2030/3076

摘要： A flow of a carrier gas through a column is provided. A sample is provided in the column, and a temperature of a longitudinally short portion of the column is raised to a predetermined controlled high temperature at which volatile substances are released from the sample packing and are carried by the carrier gas. The column is cooled on each side of the short portion to a low temperature at which the volatile substances condense or adsorb on the column packing. By continuously moving the heated short portion from an inlet end to an outlet end of the packing in a direction of carrier gas flow the volatile substances selected by the controlled high temperature are released. Four particularly useful and advantageous applications can be identified for the invention. Firstly, it provides an improved gas chromatograph (GC) injector. Secondly, it provides an improved thermal separator or extractor. Thirdly, it provides an efficient way to analyze target compounds suspected of being contained within a complex mixture by allowing for the GC analysis to be carried out only on those compounds or substances falling within the same or similar thermal desorption characteristics as those of the target compound. Lastly, by operating in a full time-coupled time-resolved (TCRC) mode, a complete three-dimensional analysis output can be obtained giving better power of separation of the analyzed sample, which is of particular importance when the substance to be analyzed is a complex organic material.

摘要翻译： 提供通过柱的载气流。 在塔中设置样品，将柱的纵向短部分的温度升高到从样品填料释放挥发性物质并由载气承载的预定控制高温。 将柱在短部分的每一侧冷却至低挥发性物质冷凝或吸附在柱状填料上的低温。 通过将加热的短部分沿着载气流动的方向从填料的入口端到出口端连续移动，释放由受控高温选择的挥发性物质。 可以鉴定本发明的四个特别有用和有利的应用。 首先，它提供了改进的气相色谱（GC）注射器。 其次，它提供了一种改进的热分离器或提取器。 第三，它提供了一种有效的方式来分析怀疑含有在复杂混合物中的目标化合物，只允许GC分析只对那些与目标化合物相同或相似的热解吸特性的化合物或物质进行 。 最后，通过以全时间耦合时间分辨（TCRC）模式运行，可以获得完整的三维分析输出，从而获得更好的分析样本分离能力，当待分析物质为 复杂的有机材料。

公开(公告)号：US5565622A

公开(公告)日：1996-10-15

申请号：US306551

申请日：1994-09-15

申请人： Gregory E. Murphy

发明人： Gregory E. Murphy

IPC分类号： G01N1/00 ,  G01N1/10 ,  G01N1/34 ,  G01N30/00 ,  G01N30/02 ,  G01N30/04 ,  G01N30/06 ,  G01N30/08 ,  G01N30/12 ,  G01N30/16 ,  G01N30/18 ,  G01N30/24 ,  G01N13/00

CPC分类号： G01N1/405 ,  G01N30/08 ,  G01N2030/025 ,  G01N2030/065 ,  G01N2030/085 ,  G01N2030/122 ,  G01N2030/128 ,  G01N2030/167 ,  G01N30/18 ,  G01N30/24

摘要： A simplified method for solid phase extraction of components of interest from a sample employing a syringe in which the inner surface of the cannula or needle is at least partially coated with a stationary phase such that aspirating the sample into the needle results in adsorption of the components of interest into the stationary phase. Aspiration of a solvent may be employed for removing the components of interest from the stationary phase for direct injection into a chromatographic instrument, or the components of interest may be removed by thermal desorption, wherein the needle is placed in the injection port of the chromatographic instrument and heated.

摘要翻译： 从使用注射器的样品中固相萃取感兴趣组分的简化方法，其中套管或针的内表面至少部分地涂覆有固定相，从而将样品吸入针中导致组分的吸附 对固定相感兴趣。 溶剂的吸入可用于从固定相中除去感兴趣的组分以直接注入色谱仪器中，或者可通过热解吸去除感兴趣的组分，其中将针放置在色谱仪的注射口中 并加热。

公开(公告)号：US5479815A

公开(公告)日：1996-01-02

申请号：US201254

申请日：1994-02-24

申请人： James D. White ,  William R. Croasmun ,  Jane V. Leland

发明人： James D. White ,  William R. Croasmun ,  Jane V. Leland

IPC分类号： G01N30/12 ,  G01N30/72 ,  G01N33/00 ,  G01N33/02 ,  G01N33/497 ,  G01N31/00 ,  G01N33/16

CPC分类号： A61B5/082 ,  A61B5/097 ,  G01N30/12 ,  G01N33/02 ,  G01N33/497 ,  G01N2030/122 ,  G01N2030/123 ,  G01N30/7206 ,  G01N33/0011 ,  G01N33/0047

摘要： The invention provides a method and apparatus for efficiently measuring and analyzing volatile and relatively non-volatile flavor components released during oral processing of food or other products. The subject exhales a breath sample into one or more temperature-controlled collection chambers, preferably at predetermined time intervals during the oral processing of the product. Each breath sample is then purged from its collection chamber with a non-reactive gas flow into an adsorbent, absorbent or other trap containing an interface that separates and collects the volatile and relatively non-volatile components from the breath sample. The trap is then transferred to a thermal desorber to release the volatile and relatively non-volatile flavor components from the interface surface into a measuring and analysis apparatus.

摘要翻译： 本发明提供了一种用于有效测量和分析在食品或其他产品的口腔加工期间释放的挥发性和相对非挥发性风味成分的方法和装置。 受试者在口服产品的口腔加工过程中，优选以预定的时间间隔将呼吸样品呼气至一个或多个温度控制的收集室中。 然后将每个呼吸样品从其收集室中以非反应性气流吹入吸附剂，吸收剂或其它含有从呼吸样品中分离和收集挥发性和相对非挥发性组分的界面的阱。 然后将捕集器转移到热解吸器以将挥发性和相对非挥发性的风味成分从界面表面释放到测量和分析装置中。

公开(公告)号：US5228514A

公开(公告)日：1993-07-20

申请号：US978640

申请日：1992-11-19

申请人： Raymond D. Worden ,  Lawrence R. Kubecka

发明人： Raymond D. Worden ,  Lawrence R. Kubecka

IPC分类号： B01D5/00 ,  B01D7/02 ,  G01N1/00 ,  G01N1/22 ,  G01N1/28 ,  G01N1/40 ,  G01N30/00 ,  G01N30/12 ,  G01N30/30

CPC分类号： G01N30/12 ,  B01D5/0003 ,  B01D5/0096 ,  B01D7/02 ,  G01N30/00 ,  G01N1/2252 ,  G01N1/4077 ,  G01N2001/2282 ,  G01N2001/4027 ,  G01N2030/008 ,  G01N2030/122 ,  G01N2030/125 ,  G01N2030/128 ,  G01N2030/3023 ,  G01N2030/3053 ,  G01N2030/3076

摘要： A gas trap apparatus is disclosed for trapping gaseous fraction of mixtures. The apparatus includes a gas column chamber into which a tubular column, such as a capillary tube, may extend. A cooling chamber is provided into which a coolant may be introduced for solidifying or liquefying a gas sample. A heating element in surrounding relationship to the cooling chamber is used for vaporizing the solidified/liquified gas. A Dewar flask surrounds the gas trap apparatus to prevent thermal leakage to the atmosphere.

摘要翻译： 公开了一种用于捕集混合物的气体馏分的气体捕集装置。 该装置包括气柱室，诸如毛细管的管状柱可以延伸到该气室中。 提供冷却室，冷却剂可以被引入其中，以使气体样品固化或液化。 使用与冷却室相关的加热元件来蒸发凝固/液化的气体。 杜瓦瓶围绕气体收集装置，以防止热量泄漏到大气中。

公开(公告)号：US5196039A

公开(公告)日：1993-03-23

申请号：US846330

申请日：1992-03-06

申请人： John B. Phillips ,  Zaiyou Liu

发明人： John B. Phillips ,  Zaiyou Liu

IPC分类号： G01N1/22 ,  G01N27/447 ,  G01N30/12 ,  G01N30/30 ,  G01N30/46 ,  G01N30/56 ,  G01N30/60 ,  G01N30/62 ,  G01N30/86

CPC分类号： G01N30/463 ,  G01N27/44773 ,  G01N30/30 ,  G01N2001/2229 ,  G01N2030/122 ,  G01N2030/123 ,  G01N2030/303 ,  G01N2030/567 ,  G01N2030/623 ,  G01N30/461 ,  G01N30/465 ,  G01N30/6047 ,  G01N30/8658

摘要： A practical device and method of performing comprehensive multi-dimensional chemical separation using a first dimension of a two-dimensional chromatograph to generate a chromatogram in a time comparable to or even faster than common practice while the second dimension generates multiple chromatograms each in a time comparable to the fastest prior art chromatography. The transfer of sample portions from the first dimension to the second dimension is by any one of several sample stream modulation techniques. These techniques accumulate portions of sample between the first and the second dimensions transferring them as very sharp concentration pulses analogous to fast injections, without loss of sample and with a substantial improvement in sensitivity.

摘要翻译： 使用二维色谱仪的第一维进行全面多维化学分离的实用装置和方法，以在与常规实践相当或甚至更快的时间产生色谱图，而第二维度在时间上产生多个色谱图 到最快的现有技术色谱。 样本部分从第一维度传递到第二维度是通过几种样本流调制技术中的任何一种。 这些技术在第一和第二维之间累积样品的部分，将它们作为类似于快速注射的非常尖锐的浓度脉冲转移，而不损失样品并且具有显着的灵敏度提高。

公开(公告)号：US5092157A

公开(公告)日：1992-03-03

申请号：US81918

申请日：1987-07-08

申请人： Eugene K. Achter ,  Alf L. Carroll ,  David P. Rounbehler ,  David H. Fine ,  Freeman W. Fraim

发明人： Eugene K. Achter ,  Alf L. Carroll ,  David P. Rounbehler ,  David H. Fine ,  Freeman W. Fraim

IPC分类号： G01N1/00 ,  G01N1/02 ,  G01N1/22 ,  G01N1/28 ,  G01N1/40 ,  G01N21/76 ,  G01N27/417 ,  G01N30/02 ,  G01N30/06 ,  G01N30/08 ,  G01N30/12 ,  G01N30/14 ,  G01N30/16 ,  G01N30/30 ,  G01N30/40 ,  G01N30/46 ,  G01N30/62 ,  G01N30/64 ,  G01N30/72 ,  G01N30/84 ,  G01N31/12 ,  G01N33/00 ,  G01N33/22 ,  G01V9/00

CPC分类号： G01N30/461 ,  G01N1/02 ,  G01N30/08 ,  G01N30/12 ,  G01N30/84 ,  G01N33/0057 ,  G01V9/007 ,  G01N1/2214 ,  G01N1/2226 ,  G01N1/28 ,  G01N1/40 ,  G01N2001/022 ,  G01N2001/028 ,  G01N2030/025 ,  G01N2030/065 ,  G01N2030/085 ,  G01N2030/121 ,  G01N2030/122 ,  G01N2030/123 ,  G01N2030/125 ,  G01N2030/126 ,  G01N2030/143 ,  G01N2030/167 ,  G01N2030/3007 ,  G01N2030/3046 ,  G01N2030/3053 ,  G01N2030/3061 ,  G01N2030/3069 ,  G01N2030/3076 ,  G01N2030/3084 ,  G01N2030/626 ,  G01N2030/642 ,  G01N2030/8405 ,  G01N21/76 ,  G01N30/14 ,  G01N30/40 ,  G01N30/62 ,  G01N30/72

摘要： A highly selective, sensitive, fast detection system and method are disclosed for detecting vapors of specific compounds in air. Vapors emanating from compounds such as explosives, or stripped from surfaces using heat and suction from a hand-held sample gun, are collected on surfaces coated with gas chromatograph (GC) material which trap explosives vapors but repel nitric oxide, then are desorbed and concentrated in one or more cold spot concentrators. A high speed gas chromatrograph (GC) separates the vapors, after which specific vapors are decomposed in two pyrolyzers arranged in parallel and the resulting nitric oxide is detected. A low temperature pyrolyzer with silver produces NO from nitramines or nitrite esters; a high temperature pyrolyzer decomposes all explosives vapors to permit detection of the remaining explosives. Also disclosed is a series arrangement of pyrolyzers and gas chromatographs and an NO detector to time-shift detection of certain vapors and facilitate very fast GC analyses. The use of hydrogen as a carrier gas, plus unique collectors and concentrators, high speed heaters, NO detectors, and very fast, temperature-programmable GC's enhance selectivity, sensitivity and speed of detection.

摘要翻译： 公开了一种高选择性，灵敏，快速的检测系统和方法，用于检测空气中特定化合物的蒸气。 从化合物如爆炸物或从手持式样品枪吸取热量从表面剥离的蒸气被收集在涂有气相色谱（GC）材料的表面上，该气相色谱（GC）材料捕获爆炸物蒸气但排斥一氧化氮，然后被解吸和浓缩 在一个或多个冷点浓缩器中。 高速气相色谱仪（GC）分离蒸汽，之后特定的蒸气在平行排列的两个热解器中分解，并检测到所产生的一氧化氮。 含有银的低温热解器由硝胺或亚硝酸酯产生NO; 高温热解器分解所有炸药蒸气，以便检测剩余的炸药。 还公开了热解器和气相色谱仪的串联布置和用于某些蒸气的时移检测的NO检测器，并且促进非常快速的GC分析。 使用氢气作为载气，加上独特的收集器和浓缩器，高速加热器，NO检测器和非常快速的温度可编程GC增强了选择性，灵敏度和检测速度。

公开(公告)号：US4837434A

公开(公告)日：1989-06-06

申请号：US71492

申请日：1987-07-09

申请人： Craig A. James

发明人： Craig A. James

IPC分类号： H01J37/26 ,  G01N27/62 ,  G01N30/00 ,  G01N30/12 ,  G01N30/72 ,  H01J49/02 ,  H01J49/04

CPC分类号： G01N30/72 ,  H01J49/022 ,  H01J49/04 ,  G01N2030/0035 ,  G01N2030/0055 ,  G01N2030/122

摘要： A gas chromatography plus mass spectrometry system implements a scan strategy in which each full range scan alternates between a normal measurement mode and a survey mode based on a block/gap map made during the previous scan. Survey mode is used within regions that were determined in the previous scan to lack signal above a predetermined threshold. Spectral data is generated during measurement mode operation. Each scan serves both measurement and mapping functions in a way that avoids mass filter jumps, since each scan is monotonic over the entire scanning range.