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公开(公告)号:US12109410B2
公开(公告)日:2024-10-08
申请号:US17216423
申请日:2021-03-29
IPC分类号: A61N1/32 , A61B5/243 , A61M5/142 , A61M39/00 , A61M39/02 , A61N1/36 , A61N1/362 , A61N1/372 , A61N1/375
CPC分类号: A61N1/326 , A61M39/0208 , A61N1/37205 , A61N1/375 , A61B5/243 , A61M5/14276 , A61M2039/0036 , A61M2202/07 , A61M2205/05 , A61M2205/50 , A61M2205/502 , A61N1/36002 , A61N1/36007 , A61N1/36071 , A61N1/36114 , A61N1/3629
摘要: Described is a low voltage, pulsed electrical stimulation device for controlling expression of, for example, follistatin, a muscle formation promotion protein, by tissues. Epicardial stimulation is especially useful for heart treatment. Follistatin controlled release is also useful for treating other ailments, such as erectile dysfunction, aortic aneurysm, and failing heart valves.
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公开(公告)号:US20240285940A1
公开(公告)日:2024-08-29
申请号:US18656710
申请日:2024-05-07
发明人: Yossi GROSS , Gideon FOSTICK
CPC分类号: A61N1/205 , A61N1/0551 , A61N1/306 , A61N1/325 , A61N1/326 , A61N1/327 , A61N1/36062 , A61N1/36132 , A61N1/37205 , A61N1/37518
摘要: Apparatus for treating an intervertebral disc of a subject is provided. The apparatus includes at least three intra-pulposus exposed electrode surfaces, which are configured to be implanted within a nucleus pulposus of the disc, at different respective locations; and one or more extra-pulposus exposed electrode surfaces, which are configured to be implanted outside the nucleus pulposus, in electrical communication with the disc. Control circuitry is configured to (a) configure the intra-pulposus exposed electrode surfaces to be cathodes, and the one or more extra-pulposus exposed electrode surfaces to be one or more anodes, and (b) drive the intra-pulposus exposed electrode surfaces and the one or more extra-pulposus exposed electrode surfaces to electroosmotically drive fluid into the nucleus pulposus to increase pressure in the disc.
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公开(公告)号:US12011592B2
公开(公告)日:2024-06-18
申请号:US16664085
申请日:2019-10-25
发明人: John Claude , Christopher A. Wiklof
IPC分类号: A61N1/08 , A61B5/053 , A61N1/02 , A61N1/04 , A61N1/20 , A61N1/36 , A61B5/00 , A61B18/14 , A61N1/32
CPC分类号: A61N1/36031 , A61B5/053 , A61N1/02 , A61N1/025 , A61N1/04 , A61N1/0428 , A61N1/0456 , A61N1/0472 , A61N1/08 , A61N1/205 , A61N1/36 , A61N1/3601 , A61N1/36014 , A61N1/36021 , A61N1/36034 , A61B5/6814 , A61B5/7225 , A61B18/14 , A61N2001/083 , A61N1/326 , A61N1/3603
摘要: A microcurrent treatment device includes an adaptive trigger circuit configured to dynamically determine a triggering threshold for applying a therapeutic microcurrent via a treatment electrode to a nerve node on a person's face for treatment of a sinus condition.
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公开(公告)号:US20240131330A1
公开(公告)日:2024-04-25
申请号:US18397104
申请日:2023-12-27
申请人: Theragen, Inc.
CPC分类号: A61N1/36031 , A61B5/4833 , A61N1/0464 , A61N1/0468 , A61N1/0492 , A61N1/326 , A61N1/36034
摘要: Systems, devices and methods are provided for transcutaneously delivering energy impulses to bodily tissues for therapeutic purposes, such as for enhancing the body's bone healing process in spinal fusion patients. A therapeutic stimulator system comprises a housing for an energy source and a signal generator. The system further includes one or more electrodes coupled to the signal generator. A processor is coupled to the housing and configured to determine usage levels of the signal generator and/or motion data of the housing. The system may include a mobile device that allows the patient to input user status data, such as pain levels, and compare the user status data with the usage levels and/or the motion data, thereby improving patient compliance with a prescribed therapy regimen.
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公开(公告)号:US11963714B2
公开(公告)日:2024-04-23
申请号:US17347179
申请日:2021-06-14
发明人: Mark E. Deem , Hanson S. Gifford, III , Denise Zarins , Douglas Sutton , Erik Thai , Mark Gelfand , Howard R. Levin
IPC分类号: A61B18/14 , A61B8/08 , A61B8/12 , A61B18/00 , A61B18/12 , A61B18/18 , A61M5/14 , A61M25/00 , A61N1/04 , A61N1/05 , A61N1/18 , A61N1/20 , A61N1/32 , A61N1/36 , A61N5/00 , A61N7/00
CPC分类号: A61B18/1492 , A61B8/0891 , A61B8/12 , A61B18/1206 , A61B18/1233 , A61B18/18 , A61M5/14 , A61M25/0023 , A61N1/05 , A61N1/0551 , A61N1/18 , A61N1/205 , A61N1/327 , A61N1/36007 , A61N1/36017 , A61N1/36057 , A61N1/36103 , A61N1/36114 , A61N1/36139 , A61N5/00 , A61N7/00 , A61B2018/00071 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00613 , A61B2018/00642 , A61B2018/00904 , A61B2018/126 , A61B2018/1467 , A61N1/0412 , A61N1/326 , A61N1/36117 , A61N2007/0021 , A61N2007/003
摘要: Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.
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公开(公告)号:US20240123221A1
公开(公告)日:2024-04-18
申请号:US18379256
申请日:2023-10-12
申请人: Novocure GmbH
发明人: Ariel NAVEH
CPC分类号: A61N1/326 , A61N1/36014 , A61N1/40
摘要: A computer-implemented method to determine locations of transducers to apply tumor treating fields to a target tissue of a subject's body, the method comprising: obtaining a three-dimensional model of at least a portion of the subject's body; and identifying a first location on the three-dimensional model to place a first transducer, wherein the first transducer has a first surface to be located facing the subject's body, wherein the first transducer has at least one electrode element adapted to provide tumor treating fields, wherein when viewed from a direction perpendicular to the first surface of the first transducer, an area of the at least one electrode element of the first transducer ranges from approximately 150 cm2 to approximately 265 cm2.
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公开(公告)号:US11819688B2
公开(公告)日:2023-11-21
申请号:US17368499
申请日:2021-07-06
IPC分类号: A61N1/32 , A61H39/00 , A61N5/06 , A61M37/00 , A61K8/98 , A61Q19/08 , A61M39/02 , A61N1/362 , A61N1/36 , A61N1/372 , A61M5/142 , A61M39/00 , A61N5/067
CPC分类号: A61N1/328 , A61H39/002 , A61K8/981 , A61K8/982 , A61M37/0015 , A61M39/0208 , A61N1/326 , A61N1/327 , A61N5/0616 , A61Q19/08 , A61H2201/10 , A61K2800/83 , A61M5/14276 , A61M2037/0023 , A61M2037/0061 , A61M2039/0036 , A61M2202/0494 , A61M2202/07 , A61M2202/09 , A61M2205/05 , A61M2205/50 , A61M2205/502 , A61N1/36002 , A61N1/3629 , A61N1/37205 , A61N5/067 , A61N2005/0647 , A61N2005/0648 , A61N2005/0652
摘要: A skin regeneration therapy combining precise bioelectric signals, light, and biologics for skin treatment and regeneration. Precise bioelectric signals give clear instructions to the stimulated cell DNA/RNA to produce specific regenerative proteins on demand. Bioelectric signals give clear instructions to cell membranes on what to let in and what to let out and serve as an equivalent or surrogate of environmental stimuli to cause a cell action in response.
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公开(公告)号:US11759637B2
公开(公告)日:2023-09-19
申请号:US17887630
申请日:2022-08-15
申请人: Theragen, Inc.
CPC分类号: A61N1/36031 , A61B5/4833 , A61N1/0464 , A61N1/0468 , A61N1/0492 , A61N1/326 , A61N1/36034
摘要: Systems, devices and methods are provided for transcutaneously delivering energy impulses to bodily tissues for therapeutic purposes, such as for enhancing the body's bone healing process in spinal fusion patients. A therapeutic stimulator system comprises a housing for an energy source and a signal generator. The system further includes one or more electrodes coupled to the signal generator. A processor is coupled to the housing and configured to determine usage levels of the signal generator and/or motion data of the housing. The system may include a mobile device that allows the patient to input user status data, such as pain levels, and compare the user status data with the usage levels and/or the motion data, thereby improving patient compliance with a prescribed therapy regimen.
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公开(公告)号:US20230173268A1
公开(公告)日:2023-06-08
申请号:US18052100
申请日:2022-11-02
发明人: Tsutomu SUGAYA , Keita YAMADA , Shingo BAN , Kei DOKAI , Tomoaki UEDA , Shunsuke YAMAGUCHI , Kazunari MATOBA
CPC分类号: A61N1/326 , A61N1/06 , A61N1/0548 , A61C5/40 , A61N2001/083
摘要: A treatment device that shortens the time period until healing is determined even when a bone defect or a root apex lesion is generated in an apical area. The treatment device includes a file holder, a high-frequency signal generating circuit, and a control circuit. The file holder holds a file to be located in the site to be treated. The high-frequency signal generating circuit passes a high frequency current through the file. The control circuit controls a frequency of the high frequency current to be passed through the file from the high-frequency signal generating circuit. The control circuit controls the frequency of the high frequency current to be passed through the file within a range of 1.001 MHz to 11.700 MHz.
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公开(公告)号:US20180326208A1
公开(公告)日:2018-11-15
申请号:US15944168
申请日:2018-04-03
申请人: PILOGICS L.P.
发明人: Dov INGMAN , Erez MANOR
CPC分类号: A61N1/325 , A61M37/0092 , A61M2037/0007 , A61M2205/3317 , A61N1/0502 , A61N1/0526 , A61N1/322 , A61N1/326 , A61N1/36017
摘要: A device to stimulate a scalp comprises an array of stimulating elements, the stimulating elements arranged along a circumference of at least one wheel, the wheel adapted to roll over the scalp. A method of treating/preventing a hair-condition comprises: subjecting the scalp to at least 200 distinct electrode-scalp contact events during a time-interval of at most one minute and dividable into 5 non-overlapping equal-duration sub-intervals covering the time-interval, method performed such that i. for at least a majority of the electrode-scalp contact events, no electrode of the event enters into the dermis; ii. a duration of each electrode contact event is at most 100 milliseconds; and iii. for each electrode contact event, an electrical current flows between the electrode and the scalp so as to deposit electrode-released ions of a first metal or of a second metal on the scalp, thereby forming a respective metal-ion-deposition island on the user's scalp.
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