公开(公告)号：US10076471B2

公开(公告)日：2018-09-18

申请号：US15192512

申请日：2016-06-24

申请人： University of Dammam

发明人： Amal M. Nawasrah

IPC分类号： A61K6/083 ,  A61K6/00

CPC分类号： A61K6/0067 ,  A61C8/00 ,  A61C8/0013 ,  A61C13/01 ,  A61K6/0008 ,  A61K6/0017 ,  A61K6/007 ,  A61K6/083

摘要： A denture containing a henna powder or a henna extract, each of which comes from pulverized henna leaves and may include any of lawsone, tannic acid, and 2-methoxy-1,4-napthoquinone and a denture fabrication material. A denture containing at least one first antimicrobial ingredient selected from the group consisting of henna powder or a henna extract, lawsone, tannic acid, and 2-methoxy-1,4-napthoquinone, and a second antimicrobial ingredient, and optionally, a biocompatible gel and an odor neutralizer.

公开(公告)号：US09764057B2

公开(公告)日：2017-09-19

申请号：US12663052

申请日：2008-06-06

申请人： Berthold Nies

发明人： Berthold Nies

IPC分类号： A61L24/02 ,  A61L24/00 ,  A61L27/40 ,  A61K6/00 ,  A61K6/06

CPC分类号： A61L24/0084 ,  A61K6/0008 ,  A61K6/0023 ,  A61K6/0067 ,  A61K6/0643 ,  A61K6/0675 ,  A61L24/02 ,  A61L27/40 ,  A61L2430/02 ,  C08L71/02 ,  C08L33/08

摘要： The invention relates to implant materials that are based on hydraulic cements in the form of one or more pastes, suspensions or dispersions that contain mineral and/or organic and/or organomineral solids and that react, when combined or when reacted with an aqueous liquid, to a solid in a cement-type initiation reaction. The invention also relates to the use of these materials as technical, medical-technical and/or pharmaceutical products, especially as bone cements, bone replacement materials, bone glues, dental filling materials and implantable active ingredient carriers. The implant materials according to the invention in the form of one or more pastes, suspensions or dispersions that contain mineral and/or organic and/or organomineral solids are formulated in an excipient liquid in such a manner that the pastes, suspensions or dispersions are stable in storage at normal conditions over a prolonged period of time and that they react, when combined with an aqueous liquid or when added to an aqueous liquid, in a cement-type initiation reaction and set to a solid. The excipient liquid of the mineral paste, suspension or dispersion is substantially water-free, and water immiscible or insoluble or hardly soluble in water in the chemical sense.

公开(公告)号：US20170202752A1

公开(公告)日：2017-07-20

申请号：US15328780

申请日：2015-07-24

申请人： Huakun XU ,  Ning ZHANG

发明人： Huakun XU ,  Ning ZHANG

IPC分类号： A61K6/00 ,  A61K31/685

CPC分类号： A61K6/0067 ,  A61K6/0017 ,  A61K6/0029 ,  A61K6/007 ,  A61K31/685 ,  A61K6/0023 ,  C08L33/08 ,  A61K6/0026

摘要： The present invention provides protein-repellent dental materials that can be widely applied in a variety of dental applications. The protein-repellent dental materials of the invention include dental primers, dental adhesives, dental resins, dental composites, dental bonding systems and the like, as well as dental cements, dental sealants, dental bases and dental liners, each of which is protein-repellent and each of which comprises a protein-repellent agent. In certain aspects, the protein-repellent agent is 2-methacryloyloxyethyl phosphorylcholine (MPC).

公开(公告)号：US09662278B2

公开(公告)日：2017-05-30

申请号：US14765000

申请日：2014-01-31

申请人： Matthew Athanassiadis

发明人： Matthew Athanassiadis

IPC分类号： A61K6/00 ,  A61K31/56 ,  A61K6/02 ,  A61K6/06 ,  A61K31/00

CPC分类号： A61K6/0035 ,  A61K6/0038 ,  A61K6/0067 ,  A61K6/0205 ,  A61K6/0612 ,  A61K6/0625 ,  A61K6/0643 ,  A61K6/0662 ,  A61K31/00 ,  A61K31/56 ,  A61K45/06 ,  C08L71/02

摘要： The present invention discloses a root canal dental paste that has include a first portion made from at least one antibiotic compound and partially set calcium based cement which forms a matrix to at least partially encapsulate the antibiotic compound. The first portion is then ground and combined with a second portion being a non-setting material and an antibiotic to form a paste.

公开(公告)号：US09421151B2

公开(公告)日：2016-08-23

申请号：US14084103

申请日：2013-11-19

申请人： Taragenyx Limited

发明人： Rehan Ahmed ,  Gerardus Hendricus Markx

IPC分类号： B22F7/00 ,  A61K6/00 ,  B22F1/02 ,  C23C24/04 ,  A61K9/16 ,  A61K31/43 ,  C09D1/00

CPC分类号： A61K6/0067 ,  A61K9/1676 ,  A61K31/43 ,  B22F1/02 ,  B22F1/025 ,  C09D1/00 ,  C23C4/067 ,  C23C24/04 ,  Y10T428/25 ,  Y10T428/252 ,  Y10T428/254 ,  Y10T428/256 ,  Y10T428/258 ,  Y10T428/2991

摘要： A method of coating an article includes the steps of providing a powder comprising coated particles; and spray coating the powder onto a surface of the article to form a composite coating. The spray coating may be carried out by combustion spraying, gas plasma spraying, including vacuum plasma spraying (VPS), and cold spraying. The article may be an implant for surgical or dental use. The powder may include particles of metal coated calcium phosphates, especially metal coated hydroxyapatite. The particles may include bioactive agents.

公开(公告)号：US09408780B2

公开(公告)日：2016-08-09

申请号：US13359202

申请日：2012-01-26

申请人： Michael J. Borja

发明人： Michael J. Borja

IPC分类号： A61K6/083 ,  A61K47/32 ,  A61K31/56 ,  A61K6/097 ,  A61K38/28 ,  A61P35/00 ,  A61P31/00 ,  A61P29/00 ,  A61P23/00 ,  A61P31/10 ,  A61K6/00 ,  C09J171/02 ,  C09J135/08

CPC分类号： A61K6/0026 ,  A61K6/0061 ,  A61K6/0067 ,  C08L1/00 ,  C08L39/06 ,  C08L71/02 ,  C09J135/08 ,  C09J171/02 ,  C08L35/00 ,  C08L1/08

摘要： A dry tack denture adhesive hydrogel comprising a mixed salt of a copolymer of alkyl vinyl ether and maleic anhydride or maleic acid, a hygroscopic nonionic polymer, and water is provided. A method for preparation of the denture adhesive hydrogel is also disclosed.

摘要翻译： 提供了包含烷基乙烯基醚和马来酸酐或马来酸的共聚物的混合盐，吸湿性非离子聚合物和水的干粘合义齿粘合剂水凝胶。 还公开了一种制备义齿粘合剂水凝胶的方法。

公开(公告)号：US20160184190A1

公开(公告)日：2016-06-30

申请号：US14908911

申请日：2014-07-31

申请人： UCL BUSINESS PLC

发明人： Anne Margaret YOUNG

IPC分类号： A61K6/087 ,  A61K6/083 ,  A61K6/033 ,  A61K6/027 ,  A61L27/26 ,  A61L27/16 ,  A61L27/18 ,  A61L27/12 ,  A61L27/10 ,  A61L27/46 ,  A61K6/00 ,  A61L27/54

CPC分类号： A61K6/087 ,  A61K6/0067 ,  A61K6/0276 ,  A61K6/033 ,  A61K6/083 ,  A61L24/0084 ,  A61L27/10 ,  A61L27/12 ,  A61L27/16 ,  A61L27/18 ,  A61L27/26 ,  A61L27/46 ,  A61L27/48 ,  A61L27/54 ,  A61L2300/404 ,  A61L2430/02 ,  A61L2430/12 ,  C08L33/10 ,  C08L33/08

摘要： This invention provides fluid formulations and materials produced therefrom for repairing dental and bone defects, processes for the production of the fluid formulations and materials, and to uses of these formulations and materials. In particular, the invention provides the use cationic polymers such as polylysine in these formulations and materials, and the advantageous properties derived therefrom which include mechanical and antibacterial properties.

摘要翻译： 本发明提供了用于修复牙齿和骨缺损的流体制剂和由其制备的材料，用于制备流体配方和材料的方法，以及这些制剂和材料的用途。 特别地，本发明提供了在这些制剂和材料中使用阳离子聚合物如聚赖氨酸，以及由其衍生的有利性质，其包括机械和抗菌性质。

公开(公告)号：US20160128332A1

公开(公告)日：2016-05-12

申请号：US14891951

申请日：2014-05-16

申请人： THE UNIVERSITY OF BRISTOL

发明人： Michele Emily Redmond

IPC分类号： A01N47/44 ,  A01N25/12 ,  A61L15/20 ,  A61L15/44 ,  C09D5/14 ,  A61L29/08 ,  A61L29/16 ,  A61K8/43 ,  A61Q11/00 ,  A61K8/02 ,  A01N25/22 ,  A61K6/00

CPC分类号： A01N47/44 ,  A01N25/12 ,  A01N25/22 ,  A01N25/34 ,  A61K6/0008 ,  A61K6/0067 ,  A61K8/0245 ,  A61K8/044 ,  A61K8/43 ,  A61K8/55 ,  A61K2800/413 ,  A61K2800/74 ,  A61L15/20 ,  A61L15/44 ,  A61L29/08 ,  A61L29/16 ,  A61L2300/206 ,  A61L2300/404 ,  A61L2300/602 ,  A61L2300/606 ,  A61L2420/00 ,  A61Q11/00 ,  C09D5/14 ,  C09D7/63 ,  C09D7/68 ,  A01N25/08 ,  A01N25/10 ,  A61K6/0835 ,  C08L33/08

摘要： Antimicrobial micro- or nano-particles comprising a chlorhexidine salt and an anion, and a method of making the antimicrobial micro- or nanoparticle, are disclosed. The anion in the salt is selected form oxoanions and partially hydrogenated oxoanions of phosphorus, carbon, nitrogen, and sulfur.

摘要翻译： 公开了包含氯己定盐和阴离子的抗微生物微粒或纳米颗粒，以及制备抗微生物微粒或纳米颗粒的方法。 盐中的阴离子选自磷，碳，氮和硫的氧代阴离子和部分氢化的含氧阴离子。

公开(公告)号：US20160058675A1

公开(公告)日：2016-03-03

申请号：US14377313

申请日：2013-02-08

申请人： Huakun XU ,  Michael WEIR

发明人： Huakun XU ,  Michael WEIR

IPC分类号： A61K6/00 ,  A61K6/02

CPC分类号： A61K6/0067 ,  A61K6/0023 ,  A61K6/02 ,  A61K6/0235 ,  A61K6/024 ,  A61K6/0643 ,  A61K6/083 ,  C08L33/10 ,  A61K6/0029 ,  A61K6/0017

摘要： The present invention provides dental bonding agents and dental bonding systems comprising the dental bonding agents. The dental bonding agents of the invention are characterized by having antibacterial properties, and in some aspects of the invention, remineralizing properties.

摘要翻译： 本发明提供牙科粘合剂和包括牙科粘合剂的牙科粘合体系。 本发明的牙科粘合剂的特征在于具有抗菌性能，并且在本发明的一些方面，再矿化性质。

公开(公告)号：US20150064654A1

公开(公告)日：2015-03-05

申请号：US14395242

申请日：2013-04-18

申请人： RESEARCH TRIANGLE INSTITUTE

发明人： Jeffrey Robert Piascik ,  Brian R. Stoner

IPC分类号： A61C8/00 ,  A01N55/02 ,  A01N25/08 ,  A61K6/083 ,  A61K6/02

CPC分类号： A61C8/0015 ,  A01N25/08 ,  A01N55/02 ,  A61K6/0067 ,  A61K6/0094 ,  A61K6/0215 ,  A61K6/0225 ,  A61K6/0235 ,  A61K6/024 ,  A61K6/025 ,  A61K6/0255 ,  A61K6/0835 ,  A61L27/10 ,  A61L27/446 ,  A61L27/54 ,  A61L2300/104 ,  A61L2300/106 ,  A61L2300/206 ,  A61L2300/406 ,  A61L2400/18 ,  A61L2430/12 ,  Y10T29/49885 ,  A61K6/083 ,  C08L43/04 ,  C08L33/14 ,  C08L33/068 ,  C08L33/10

摘要： A fluoride treated ceramic material is provided, the ceramic material comprising fluorinated metal oxide on its surface. A method for the preparation of such treated ceramics is also provided, the method involving exposure of the ceramic to a fluorine-containing reagent. The ceramic materials can be further functionalized so as to bond to functional ligands and/or resins. The ceramic materials can be, for example, ceramic medical implants or particulate ceramic, which can be incorporated within dental and/or orthopedic composites.

摘要翻译： 提供氟化物处理的陶瓷材料，陶瓷材料在其表面上包含氟化金属氧化物。 还提供了制备这种经处理的陶瓷的方法，该方法涉及将陶瓷暴露于含氟试剂。 陶瓷材料可以进一步官能化以便键合到官能配体和/或树脂上。 陶瓷材料可以是例如陶瓷医疗植入物或颗粒陶瓷，其可以掺入牙齿和/或矫形复合材料中。