公开(公告)号：US20190200617A1

公开(公告)日：2019-07-04

申请号：US16353162

申请日：2019-03-14

申请人： The Board of Regents of the University of Texas System

发明人： Kyumin Whang

IPC分类号： A01N59/16 ,  A61L15/24 ,  A61K6/083 ,  C09D5/14 ,  A61L15/44 ,  A61K6/00 ,  A61L27/54 ,  A61L27/44

CPC分类号： A01N59/16 ,  A61K6/007 ,  A61K6/083 ,  A61L15/24 ,  A61L15/44 ,  A61L27/446 ,  A61L27/54 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2400/12 ,  C09D5/14 ,  A01N25/10 ,  C08L33/08

摘要： Methods of forming antimicrobial resin compositions comprising silver nanoparticles are disclosed, wherein the resin compositions that are generated exhibit lower initial color, reduced color shift upon storage and reduced levels of spontaneous polymerization. Such methods generally comprise: combining a silver-containing material with a self-cure and dual-cure base resin in situ wherein the base resin does not contain a catalytic amine; and adding a catalytic resin to the mixture of the resin and silver-containing material in order to form the final cured resin. Antimicrobial polymeric materials formed by said methods are also disclosed.

公开(公告)号：US20190008730A1

公开(公告)日：2019-01-10

申请号：US15748710

申请日：2016-06-23

申请人： GC Corporation

发明人： Atsushi FUJIMI ,  Syouichi FUKUSHIMA

IPC分类号： A61K6/083 ,  A61K6/00

CPC分类号： A61K6/083 ,  A61K6/0002 ,  A61K6/0052 ,  A61K6/0088 ,  A61K6/0091 ,  A61K6/06

摘要： An aspect of the present invention relates to a dental cement that includes a first agent including an organic peroxide and a (meth)acrylate; and a second agent including a thiourea derivative, an ascorbate, a vanadium compound, and a (meth)acrylate, where the first agent and the second agent each have a water content that is less than or equal to 1 mass %.

公开(公告)号：US20180325779A1

公开(公告)日：2018-11-15

申请号：US16027566

申请日：2018-07-05

申请人： DENTSPLY SIRONA Inc.

发明人： Huaibing LIU ,  Xiaoming JIN

IPC分类号： A61K6/00 ,  A61K6/083 ,  C08L33/10 ,  C08L33/08

CPC分类号： A61K6/00 ,  A61K6/0023 ,  A61K6/083 ,  C08L2666/36 ,  C08L33/10 ,  C08L33/08

摘要： Disclosed herein is a basic dental composition comprising an adhesive composition, wherein the dental composition is suitable for use in dentistry.

公开(公告)号：US20180264165A1

公开(公告)日：2018-09-20

申请号：US15982686

申请日：2018-05-17

申请人： Pioneer Surgical Technology, Inc.

发明人： Juchui Ray Lin ,  Edward S. Ahn ,  Brian M. Schlossberg

IPC分类号： A61L24/06 ,  A61K6/033 ,  A61L24/04 ,  A61K6/083 ,  A61K6/08 ,  A61L24/02

CPC分类号： A61L24/06 ,  A61K6/033 ,  A61K6/08 ,  A61K6/083 ,  A61L24/02 ,  A61L24/04 ,  A61L24/046 ,  A61L2300/112 ,  A61L2300/412 ,  A61L2400/06 ,  A61L2400/12 ,  A61L2430/02 ,  A61L2430/12

摘要： Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications. Generally, the disclosed cement product includes a first component and a second component. The first component comprises a polymerizable resin comprising ethylenic unsaturated double bond, a suitable glycidyl group and/or a suitable isocyanate group. The second component includes a compound comprising more than one type of amine selected from the group consisting of primary amine, secondary amines, tertiary amines and quaternary amines. Alternatively, the second component includes a compound comprising a suitable mercapto (SH—) group, a hindered amine or a dimethylthiotoluenediamine (DMTDA). Optionally, the cement product includes a filler and/or a bioactive component to promote bone formation.

公开(公告)号：US20180256293A1

公开(公告)日：2018-09-13

申请号：US15533220

申请日：2015-12-04

申请人： David J. Clark

发明人： David J. Clark ,  Jeremy Henderson

IPC分类号： A61C5/66 ,  A61C5/62

CPC分类号： A61C5/66 ,  A61C5/62 ,  A61C5/64 ,  A61K6/083 ,  C08L33/08

摘要： The present invention relates to methods for the restoration of a decayed portion of a tooth or re-restoration of a previously filled tooth, and to dental capsules and dental composite resin dispensers that may be used in the methods for the restoration of a decayed portion of a tooth.

公开(公告)号：US10071028B2

公开(公告)日：2018-09-11

申请号：US15315497

申请日：2015-06-10

申请人： KURARAY NORITAKE DENTAL INC.

发明人： Yamato Nojiri ,  Mitsuru Takei

IPC分类号： A61K6/083 ,  C08F216/12 ,  C08F222/26 ,  A61K6/08 ,  C08F222/10 ,  C08F22/38 ,  A61K6/087 ,  C08F220/40 ,  C08F220/34 ,  C08F236/14 ,  C08F220/20 ,  C08F30/02 ,  C08F22/10

CPC分类号： A61K6/083 ,  A61K6/00 ,  A61K6/0023 ,  A61K6/08 ,  A61K6/087 ,  C08F22/105 ,  C08F22/38 ,  C08F22/385 ,  C08F30/02 ,  C08F216/125 ,  C08F220/20 ,  C08F220/40 ,  C08F222/1006 ,  C08F222/26 ,  C08F236/14 ,  C08F2220/346 ,  C08F2222/1013 ,  C08F2222/102 ,  C08L33/26 ,  C08L33/04 ,  C08L33/14 ,  C08L43/02

摘要： The present invention provides a dental adhesive exhibiting excellent initial bond strength and bond durability to both enamel and dentin. The present invention relates to a dental adhesive containing: an asymmetric acrylamide-methacrylic acid ester compound (a); an acid group-containing (meth)acrylic polymerizable monomer (b); and a water-soluble polymerizable monomer (c). The asymmetric acrylamide-methacrylic acid ester compound (a) is represented by the following general formula (1): where X is an optionally substituted, linear or branched C1 to C6 aliphatic group or an optionally substituted aromatic group, the aliphatic group is optionally interrupted by at least one linking group selected from the group consisting of —O—, —S—, —CO—, —CO—O—, —O—CO—, —NR1—, —CO—NR1—, —NR1—CO—, —CO—O—NR1—, —O—CO—NR1—, and —NR1—CO—NR1—, and R1 is a hydrogen atom or an optionally substituted, linear or branched C1 to C6 aliphatic group.

公开(公告)号：US20180214352A1

公开(公告)日：2018-08-02

申请号：US15862955

申请日：2018-01-05

申请人： KABUSHIKI KAISHA SHOFU

发明人： Shuhei TAKAHASHI ,  Hidefumi FUJIMURA ,  Jun UCHIDA ,  Mitsuji TERAMAE

IPC分类号： A61K6/083 ,  A61K6/00

CPC分类号： A61K6/083 ,  A61K6/0023 ,  A61K6/0073 ,  A61K6/0079 ,  A61K6/0082 ,  A61K6/0088 ,  A61K6/0091 ,  A61K6/0097 ,  A61K6/09 ,  C08L75/16 ,  C08L33/14 ,  C08L33/08 ,  C08L33/10

摘要： The present invention provides a dental curable composition comprising (A) a polymerizable monomer, (B) an inorganic filler, and (C) a polymerization initiator, wherein the polymerizable monomer (A) comprises (a1) a polyfunctional (meth)acrylate monomer comprising urethane bonds, (a2) a polyfunctional (meth)acrylate monomer comprising hydroxyl groups, and (a3) a polyfunctional (meth)acrylate monomer comprising carboxyl groups, the ratio by weight of (a1):(a2)+(a3) ranges from 1:1 to 9:1, the number of hydroxyl groups is not more than 0.5 relative to the number of (meth)acryloyl groups in one molecule of the above-mentioned (a2), and the number of carboxyl groups is not more than 0.5 relative to the number of (meth)acryloyl groups in one molecule of the above-mentioned (a3).

公开(公告)号：US10004667B2

公开(公告)日：2018-06-26

申请号：US14343626

申请日：2012-09-13

申请人： Tatsuya Yamazaki ,  Hironobu Akizumi

发明人： Tatsuya Yamazaki ,  Hironobu Akizumi

IPC分类号： A61K6/00 ,  A61K6/083 ,  C08F2/44 ,  C08F292/00 ,  C08K9/04 ,  C08K3/013 ,  C08K9/08

CPC分类号： A61K6/0073 ,  A61K6/083 ,  C08F2/44 ,  C08F292/00 ,  C08K3/013 ,  C08K9/04 ,  C08K9/08 ,  C08F230/08

摘要： An organic-inorganic composite filler contains: inorganic aggregate particles formed by aggregation of inorganic primary particles with an average particle diameter of 10 to 1000 nm; an organic resin phase including a cured polymer of a polymerizable monomer covering surfaces of the inorganic primary particles and bonding the inorganic primary particles to each other, and a water absorbing resin; and aggregation gaps with a volume of micropores formed between parts of the organic resin phase of 0.01 to 0.30 cm3/g in pore volume measurement within a pore diameter range of 1 to 500 nm, as measured by a mercury intrusion technique. In a cross section passing through the centers of the inorganic aggregate particles, based on 100 measured inorganic particles, there are 10 or less inorganic aggregate particles having a macro void with a maximum width of at least 1 μm.

公开(公告)号：US09980883B2

公开(公告)日：2018-05-29

申请号：US15092101

申请日：2016-04-06

申请人： DENTSPLY SIRONA Inc.

发明人： Todd Berger ,  Adam Baratz ,  Jaclyn Vasseur

IPC分类号： A61K6/083 ,  A61K6/00

CPC分类号： A61K6/0064 ,  A61K6/0038 ,  A61K6/0058 ,  A61K6/007 ,  A61K6/083

摘要： A gutta-percha composition for filling a tooth root canal includes a temperature indicating component, such that the user has a visual indication that the material is ready for placement in the prepared canal. The material may include a thermochromatic dye, bismuth oxide or the like, in an otherwise conventional obturation material.

公开(公告)号：US09944723B2

公开(公告)日：2018-04-17

申请号：US15132508

申请日：2016-04-19

申请人： DENTSPLY SIRONA INC.

发明人： Xiaoming Jin ,  Paul D. Hammesfahr

IPC分类号： C08F2/50 ,  A61K6/00 ,  A61K6/083

CPC分类号： C08F2/50 ,  A61K6/0052 ,  A61K6/083

摘要： A photopolymerization accelerator composition improving color stability and controlling polymerization shrinkage stress of cured resin and/or the resulting composite paste thereby feature by tertiary twisted biphenyldiamine with the general formula I: R2 and R3 are each independently alkyl having from 1 to 5 carbon atoms; R and R1 are each independently hydrogen or halogen; alkyl, alkoxy, or alkylthio having from 1 to 18 carbon atoms; or phenyl and/or substituted phenyl alkoxy, or alkylthio having from 1 to 18 carbon atoms. It can be used in part with conventional photosensitizers and radically polymerizable monomers.