公开(公告)号：US10052195B2

公开(公告)日：2018-08-21

申请号：US13885366

申请日：2011-11-14

Applicant: Ronald David Blum ,  Rudy Mazzocchi

Inventor： Ronald David Blum ,  Rudy Mazzocchi

IPC: A61F2/16

CPC classification number: A61F2/1624 ,  A61F2/1613 ,  A61F2/1627 ,  A61F2/1635 ,  A61F2/1648 ,  A61F2210/008 ,  A61F2210/009

Abstract: An implantable ophthalmic device with flexible, fluid-filled membranes provide dynamically variable optical power to restore lost accommodation in individuals suffering from presbyopia or aphakia without moving parts or reducing the amount of transmitted light. Actuating the device causes the fluid-filled membrane to change curvature, which produces a corresponding change in optical power. For instance, squeezing the edge of the membrane causes the center of the membrane to bulge by an amount proportional to the squeezing force. Alternatively, heating or applying a voltage to the membrane may cause the liquid in the membrane to undergo a phase transition accompanied by a corresponding change in volume that causes the membrane to inflate so as to change the optical power of the device.

公开(公告)号：US10016278B2

公开(公告)日：2018-07-10

申请号：US12495611

申请日：2009-06-30

Applicant: Gino Bradica ,  William Christian Wattengel ,  Timothy A. Ringeisen

Inventor： Gino Bradica ,  William Christian Wattengel ,  Timothy A. Ringeisen

IPC: A61F2/02 ,  A61F2/28 ,  A61F2/30 ,  A61L27/24 ,  A61L27/48 ,  A61L27/50 ,  A61L27/52 ,  A61L27/56 ,  A61F2/44

CPC classification number: A61F2/28 ,  A61F2/30756 ,  A61F2002/30014 ,  A61F2002/30028 ,  A61F2002/30031 ,  A61F2002/30052 ,  A61F2002/30088 ,  A61F2002/30332 ,  A61F2002/3092 ,  A61F2002/30971 ,  A61F2002/4495 ,  A61F2210/008 ,  A61F2220/0033 ,  A61F2250/0018 ,  A61F2250/0043 ,  A61F2250/0051 ,  A61F2250/0056 ,  A61F2310/00365 ,  A61L27/24 ,  A61L27/48 ,  A61L27/50 ,  A61L27/52 ,  A61L27/56 ,  A61L2430/06

Abstract: Tissue implants prepared for the repair of tissues, especially avascular tissues such as cartilage. One embodiment presents an electric potential capable of receiving and accumulating desirable factors or molecules from surrounding fluid when exposed to dynamic loading. In another embodiment the implant promotes tissue conduction by retarding, restricting and controlling cellular invasion through use of gradients until competent tissue forms. Further embodiments of the tissue implants may be formed into a multi-phasic device that provides deep tissue mechanical stimulus by conduction of mechanical and fluid forces experienced at the surface of the implant.

公开(公告)号：US08478437B2

公开(公告)日：2013-07-02

申请号：US11982401

申请日：2007-10-31

Applicant: Edward S. Boyden ,  Ralph G. Dacey, Jr. ,  Colin P. Derdeyn ,  Joshua L. Dowling ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood ,  Gregory J. Zipfel

Inventor： Edward S. Boyden ,  Ralph G. Dacey, Jr. ,  Colin P. Derdeyn ,  Joshua L. Dowling ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood ,  Gregory J. Zipfel

IPC: A61F2/06 ,  G06F19/00

CPC classification number: G06T17/00 ,  A61F2/06 ,  A61F2/07 ,  A61F2/30942 ,  A61F2/90 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/30065 ,  A61F2002/30075 ,  A61F2002/30077 ,  A61F2002/30087 ,  A61F2002/30088 ,  A61F2002/3009 ,  A61F2002/30199 ,  A61F2002/30617 ,  A61F2002/3067 ,  A61F2002/3071 ,  A61F2210/0061 ,  A61F2210/0066 ,  A61F2210/0071 ,  A61F2210/008 ,  A61F2230/005 ,  A61F2230/0063 ,  A61F2240/002 ,  A61F2250/0002 ,  A61F2250/0085 ,  A61F2250/0091 ,  A61F2250/0097 ,  B33Y70/00 ,  B33Y80/00

Abstract: Methods, apparatuses, computer program products, devices and systems are described that include accepting one or more blood vessel sleeve dimensions based on blood vessel data from an individual; and making a rapid-prototyped blood vessel sleeve at least partly based on the one or more blood vessel sleeve dimensions.

Abstract translation: 描述了包括基于来自个体的血管数据接受一个或多个血管套筒尺寸的方法，装置，计算机程序产品，装置和系统; 以及至少部分地基于一个或多个血管套筒尺寸制造快速成型的血管套管。

公开(公告)号：US08333784B2

公开(公告)日：2012-12-18

申请号：US12758561

申请日：2010-04-12

Applicant: Tracee Eidenschink

Inventor： Tracee Eidenschink

IPC: A61M29/00

CPC classification number: A61F2/856 ,  A61F2/954 ,  A61F2/958 ,  A61F2210/008 ,  A61F2250/0003 ,  A61M2025/0058 ,  A61M2025/1015 ,  A61M2025/1056

Abstract: A catheter assembly includes a catheter shaft, a balloon and a pair of collars. The collars may be fixed or rotatable about a catheter shaft prior to exposure to an electric current. Where the collars are fixed to the shaft, the balloon is rotatable about the collars. When exposed to the electric current the collars expand to engage the waists of the balloon thereby sealing the balloon. Where the collars are rotatable about the shaft, each waist of the balloon is engaged to a respective collar. When the rotatable collars are exposed to the electric current the collars expand to engage the shaft of the catheter thereby sealing the balloon.

Abstract translation: 导管组件包括导管轴，气球和一对轴环。 在暴露于电流之前，套环可以围绕导管轴固定或旋转。 在套环固定到轴上的情况下，气球可围绕轴环旋转。 当暴露于电流时，套环膨胀以接合气球的腰部，从而密封气球。 在套环可绕轴旋转的情况下，球囊的每个腰部接合到相应的衣领。 当可旋转的套环暴露于电流时，套环膨胀以接合导管的轴，从而密封气球。

公开(公告)号：US07922740B2

公开(公告)日：2011-04-12

申请号：US10915209

申请日：2004-08-10

Applicant: Tracee Eidenschink ,  Jan Weber

Inventor： Tracee Eidenschink ,  Jan Weber

IPC: A61M29/00

CPC classification number: A61F2/954 ,  A61F2/856 ,  A61F2/958 ,  A61F2210/008 ,  A61F2250/0003 ,  A61M25/10 ,  A61M25/1006 ,  A61M2025/0058 ,  A61M2025/1015 ,  A61M2025/1056

Abstract: A catheter assembly comprises a catheter shaft, a balloon and a pair of collars engaged to the catheter shaft. Each collar has a body portion and at least one lip portion extending radially outward from the body portion. Each collar has a nonactivated state and an activated state, wherein in the nonactivated state the balloon is rotatable about the collars and each lip portion is constructed and arranged to abut a portion of the balloon to prevent the balloon from moving longitudinally relative thereto. In the activated state the body portion of each collar is sealingly engaged to at least a portion of the balloon.

Abstract translation: 导管组件包括导管轴，气囊和接合到导管轴的一对凸缘。 每个轴环具有主体部分和从主体部分径向向外延伸的至少一个唇部。 每个衣领都具有非活动状态和活动状态，其中在非活动状态下，气囊可围绕套环旋转，并且每个唇部被构造和布置成邻接球囊的一部分以防止球囊相对于其纵向移动。 在激活状态下，每个颈圈的主体部分密封地接合到球囊的至少一部分。

公开(公告)号：US20080201007A1

公开(公告)日：2008-08-21

申请号：US11982401

申请日：2007-10-31

Applicant: Edward S. Boyden ,  Ralph G. Dacey ,  Colin P. Derdeyn ,  Joshua L. Dowling ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood ,  Victoria Y.H. Wood ,  Gregory J. Zipfel

Inventor： Edward S. Boyden ,  Ralph G. Dacey ,  Colin P. Derdeyn ,  Joshua L. Dowling ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Clarence T. Tegreene ,  Lowell L. Wood ,  Victoria Y.H. Wood ,  Gregory J. Zipfel

IPC: G06F17/00

CPC classification number: G06T17/00 ,  A61F2/06 ,  A61F2/07 ,  A61F2/30942 ,  A61F2/90 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/30065 ,  A61F2002/30075 ,  A61F2002/30077 ,  A61F2002/30087 ,  A61F2002/30088 ,  A61F2002/3009 ,  A61F2002/30199 ,  A61F2002/30617 ,  A61F2002/3067 ,  A61F2002/3071 ,  A61F2210/0061 ,  A61F2210/0066 ,  A61F2210/0071 ,  A61F2210/008 ,  A61F2230/005 ,  A61F2230/0063 ,  A61F2240/002 ,  A61F2250/0002 ,  A61F2250/0085 ,  A61F2250/0091 ,  A61F2250/0097 ,  B33Y70/00 ,  B33Y80/00

Abstract: Methods, apparatuses, computer program products, devices and systems are described that include accepting one or more blood vessel sleeve dimensions based on blood vessel data from an individual; and making a rapid-prototyped blood vessel sleeve at least partly based on the one or more blood vessel sleeve dimensions.

公开(公告)号：US20080077265A1

公开(公告)日：2008-03-27

申请号：US11894563

申请日：2007-08-20

Applicant: Edward Boyden ,  Ralph Dacey ,  Colin Derdeyn ,  Joshua Dowling ,  Roderick Hyde ,  Muriel Ishikawa ,  Eric Leuthardt ,  Nathan Myhrvold ,  Clarence Tegreene ,  Lowell Wood ,  Victoria Wood ,  Gregory Zipfel

Inventor： Edward Boyden ,  Ralph Dacey ,  Colin Derdeyn ,  Joshua Dowling ,  Roderick Hyde ,  Muriel Ishikawa ,  Eric Leuthardt ,  Nathan Myhrvold ,  Clarence Tegreene ,  Lowell Wood ,  Victoria Wood ,  Gregory Zipfel

IPC: G06F19/00

CPC classification number: G06F19/00 ,  A61F2/06 ,  A61F2/07 ,  A61F2/30942 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2002/067 ,  A61F2002/30065 ,  A61F2002/30075 ,  A61F2002/30077 ,  A61F2002/30087 ,  A61F2002/30088 ,  A61F2002/3009 ,  A61F2002/30199 ,  A61F2002/30617 ,  A61F2002/3067 ,  A61F2002/3071 ,  A61F2210/0061 ,  A61F2210/0066 ,  A61F2210/0071 ,  A61F2210/008 ,  A61F2230/005 ,  A61F2230/0063 ,  A61F2240/002 ,  A61F2250/0002 ,  A61F2250/0085 ,  A61F2250/0091 ,  A61F2250/0097 ,  B33Y80/00 ,  G06Q10/06 ,  G06Q10/087 ,  G06T17/00

Abstract: Methods, apparatuses, computer program products, devices and systems are described that include accepting one or more blood vessel sleeve dimensions based on blood vessel data from an individual; and making a rapid-prototyped blood vessel sleeve at least partly based on the one or more blood vessel sleeve dimensions.

Abstract translation: 描述了包括基于来自个体的血管数据接受一个或多个血管套筒尺寸的方法，装置，计算机程序产品，装置和系统; 以及至少部分地基于一个或多个血管套筒尺寸制造快速原型血管套管。

公开(公告)号：US20060025859A1

公开(公告)日：2006-02-02

申请号：US11044697

申请日：2005-01-27

Applicant: Nils Stelter ,  Helmut Wild

Inventor： Nils Stelter ,  Helmut Wild

IPC: A61F2/52

CPC classification number: A61F2/52 ,  A61F2/5046 ,  A61F2002/5056 ,  A61F2002/5083 ,  A61F2002/523 ,  A61F2002/7806 ,  A61F2002/7881 ,  A61F2210/008

Abstract: The invention relates to a breast prosthesis substantially consisting of bodies welded in plastic films and modeled on the shape of the breast, preferably of an addition cross-linked two-component silicone rubber mass, on whose rear side, in accordance with the invention, a separate and exchangeably insert can be put in or on.

Abstract translation: 本发明涉及一种乳房假体，其基本上由焊接在塑料膜上并以乳房形状为模型的主体组成，优选地是加成交联的双组分硅橡胶块，其背面根据本发明， 可以插入或分开插入。

公开(公告)号：US20050187602A1

公开(公告)日：2005-08-25

申请号：US10785449

申请日：2004-02-24

Applicant: Tracee Eidenschink

Inventor： Tracee Eidenschink

IPC: A61F2/00 ,  A61F2/02 ,  A61F2/06 ,  A61F2/84

CPC classification number: A61F2/856 ,  A61F2/954 ,  A61F2/958 ,  A61F2210/008 ,  A61F2250/0003 ,  A61M2025/0058 ,  A61M2025/1015 ,  A61M2025/1056

Abstract: A catheter assembly comprises a catheter shaft, a balloon and a pair of collars. The collars may be fixed or rotatable about a catheter shaft prior to exposure to an electric current. Where the collars are fixed to the shaft, the balloon is rotatable about the collars. When exposed to the electric current the collars expand to engage the waists of the balloon thereby sealing the balloon. Where the collars are rotatable about the shaft, the each waist of the balloon is engaged to a respective collars. When the rotatable collars are exposed to the electric current the collars expand to engage the shaft of the catheter thereby sealing the balloon.

Abstract translation: 导管组件包括导管轴，气球和一对项圈。 在暴露于电流之前，套环可以围绕导管轴固定或旋转。 在套环固定到轴上的情况下，气球可围绕轴环旋转。 当暴露于电流时，套环膨胀以接合气球的腰部，从而密封气球。 在套环可围绕轴旋转的情况下，球囊的每个腰部接合到相应的套环。 当可旋转的套环暴露于电流时，套环膨胀以接合导管的轴，从而密封气球。

公开(公告)号：US11890393B2

公开(公告)日：2024-02-06

申请号：US17138703

申请日：2020-12-30

Applicant: Tulavi Therapeutics, Inc. ,  Incept, LLC

Inventor： Corinne Bright ,  Yong Ren ,  Kenneth M. Martin ,  Farhad Khosravi ,  Amarpreet S. Sawhney

IPC: A61B17/11 ,  A61F2/00 ,  A61F2/02 ,  A61K9/00 ,  A61L27/52 ,  A61L31/14 ,  A61B17/00 ,  A61L27/26 ,  A61L27/18

CPC classification number: A61L27/26 ,  A61B17/1128 ,  A61F2/00 ,  A61F2/02 ,  A61K9/0004 ,  A61L27/18 ,  A61L27/52 ,  A61L31/14 ,  A61B2017/00526 ,  A61F2210/00 ,  A61F2210/008 ,  A61F2240/00 ,  A61F2240/001 ,  A61F2250/00 ,  A61L2400/06 ,  A61L2430/32

Abstract: Disclosed are methods, devices and materials for the in situ formation of a nerve cap to inhibit neuroma formation following planned or traumatic nerve injury. The method includes the steps of identifying a severed end of a nerve, and positioning the severed end into a cavity defined by a form. A transformable media is introduced into the form cavity to surround the severed end. The media is permitted to undergo a transformation from a first, relatively flowable state to a second, relatively non flowable state to form a protective barrier surrounding the severed end. The media may be a hydrogel, and the transformation may produce a synthetic crosslinked hydrogel protective barrier. The media may include at least one anti-regeneration agent to inhibit nerve regrowth.