公开(公告)号：US12097008B1

公开(公告)日：2024-09-24

申请号：US17938025

申请日：2022-10-04

申请人： ViOptix, Inc.

发明人： Larry C. Heaton, II ,  Robert E. Lash ,  Jimmy Jian-min Mao

IPC分类号： A61B5/00 ,  A61B1/018 ,  A61B1/06 ,  A61B1/31 ,  A61B5/145 ,  A61B5/1455 ,  A61B17/122 ,  A61B17/12

CPC分类号： A61B5/0024 ,  A61B1/018 ,  A61B1/0638 ,  A61B1/31 ,  A61B5/14503 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/4255 ,  A61B5/6848 ,  A61B5/6852 ,  A61B5/7282 ,  A61B5/742 ,  A61B17/122 ,  A61B5/0095 ,  A61B5/1455 ,  A61B2017/12004 ,  A61B2505/05 ,  A61B2560/0223 ,  A61B2562/0233

摘要： Devices and systems have a sensor probe configured to measure tissue oxygen saturation in the intestine or mesentery. The devices and systems can determine the oxygenation state of the entire thickness of the intestine or mesentery. Embodiments of the invention also include methods for inducing a temporary ischemic period in an intestine or mesentery tissue and analyzing changes in oxygen saturation of the tissue during the temporary ischemic period or during a recovery phase. The devices, systems, and methods can be applied in diagnosing intestinal ischemia in a patient, as well as in monitoring tissue oxygen saturation of the intestine or mesentery during or after a surgical procedure.

公开(公告)号：US20240303816A1

公开(公告)日：2024-09-12

申请号：US18599573

申请日：2024-03-08

申请人： Motilent Limited

发明人： Andrew Bard ,  Benjamin Barrow ,  Alexander Menys

IPC分类号： G06T7/00 ,  A61B5/00 ,  A61B5/055 ,  G06T7/11 ,  G06T7/136 ,  G16H30/20 ,  G16H50/50

CPC分类号： G06T7/0014 ,  A61B5/055 ,  A61B5/4255 ,  G06T7/11 ,  G06T7/136 ,  G16H30/20 ,  G16H50/50 ,  G06T2200/24 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/20092 ,  G06T2207/30028

摘要： A method of segmenting a bowel includes receiving patient imaging comprising one or more voxels; determining a lumen indicator based on the patient imaging; representing the one or more voxels within a distance of the lumen indicator as one or more feature vectors; generating, based on the one or more feature vectors, a cluster comprising at least one of the one or move voxels; binarizing the cluster into one or more groups based on a threshold value; and generating a bowel segment model based at least on the cluster.

公开(公告)号：US12070321B2

公开(公告)日：2024-08-27

申请号：US17348954

申请日：2021-06-16

申请人： Boston Scientific Scimed, Inc.

发明人： George Wilfred Duval ,  Namita M. Kallur

IPC分类号： A61B5/00 ,  A61B5/07 ,  A61B5/107 ,  A61B5/026 ,  A61B5/0295

CPC分类号： A61B5/4216 ,  A61B5/073 ,  A61B5/1076 ,  A61B5/4238 ,  A61B5/4255 ,  A61B5/7264 ,  A61B5/0086 ,  A61B5/0261 ,  A61B5/0295 ,  A61B5/1072 ,  A61B5/4233 ,  A61B5/6861

摘要： A method for evaluating a gastrointestinal tract of a subject may comprise using a sensor located in the subject to obtain data regarding qualities of a tissue of the gastrointestinal tract; using the obtained data, determining a measure of perfusion of blood in the tissue; using the obtained data, determining a measure of thickness of the tissue; using the measure of perfusion and the measure of thickness, determining a measure of inflammation of the tissue; and using one or more of the measure of perfusion, the measure of thickness, and the measure of inflammation, classifying a state of the tissue.

公开(公告)号：US11933790B2

公开(公告)日：2024-03-19

申请号：US17159731

申请日：2021-01-27

申请人： UNIVERSITY OF OTTAWA

发明人： Joseph Michel Daniel Figeys ,  Alain Christophe Stintzi ,  David R. Mack ,  Xu Zhang ,  Zhibin Ning

IPC分类号： G01N33/68 ,  A61B5/00 ,  C12Q1/16 ,  G01N33/50 ,  G16B30/10 ,  G16B40/10 ,  G16B40/20 ,  G16H50/20 ,  G16H50/30 ,  G16H50/70

CPC分类号： G01N33/6848 ,  A61B5/4255 ,  C12Q1/16 ,  G01N33/5023 ,  G01N33/5091 ,  G16B30/10 ,  G16B40/10 ,  G16B40/20 ,  G16H50/20 ,  G16H50/30 ,  G16H50/70 ,  A61B2503/42 ,  G01N2223/01 ,  G01N2570/00 ,  G01N2800/06

摘要： A method of isotope-labelling a microbiota sample. It involves providing a first microbiota sample that was obtained from a given source; exposing the first microbiota sample to an isotope enriched medium; and culturing the exposed first microbiota sample in the isotope enriched medium to obtain an isotope-labelled microbiota sample, wherein the isotope labelled metaproteome of the isotope-labelled microbiota sample is taxon specific for taxa present in the first microbiota sample when initially obtained from the given source.

公开(公告)号：US20240041389A1

公开(公告)日：2024-02-08

申请号：US18382009

申请日：2023-10-19

申请人： DAIKIN INDUSTRIES, LTD.

发明人： Nozomi YAMADA ,  Sanae MIKI ,  Tomoya HIRANO ,  Takahiro HIRAYAMA ,  Masahiro KATO

IPC分类号： A61B5/00

CPC分类号： A61B5/4255 ,  A61B5/742 ,  A61B5/4839

摘要： An intestinal activity regulation device includes a regulator that performs a regulation process of regulating intestinal activity of a target person based on the state of the intestinal activity detected by a detector that detects the state of the intestinal activity of the target person.

公开(公告)号：US11864878B2

公开(公告)日：2024-01-09

申请号：US17180264

申请日：2021-02-19

申请人： Boston Scientific Scimed, Inc.

发明人： George Wilfred Duval ,  Michael Y. Ko ,  James Weldon ,  Namita M. Kallur

IPC分类号： A61B5/026 ,  A61B5/107 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/0205 ,  A61B5/349 ,  A61B5/027 ,  A61B5/0295 ,  A61B5/0285

CPC分类号： A61B5/0261 ,  A61B5/0086 ,  A61B5/0205 ,  A61B5/1072 ,  A61B5/14551 ,  A61B5/349 ,  A61B5/4255 ,  A61B5/6853 ,  A61B5/6858 ,  A61B5/027 ,  A61B5/0285 ,  A61B5/0295 ,  A61B5/4216 ,  A61B5/4233 ,  A61B5/4238 ,  A61B2562/043

摘要： A system may include an expandable member, and a plurality of sensors disposed on an outer surface of the expandable member and circumferentially spaced apart from one another, wherein each of the plurality of sensors includes a first emitter configured to emit light of a first wavelength, and a detector configured to detect light, and a controller coupled to the plurality of sensors.

公开(公告)号：US11791020B2

公开(公告)日：2023-10-17

申请号：US15999470

申请日：2017-02-17

申请人： Icahn School of Medicine at Mount Sinai

发明人： Ashish Atreja ,  Jason Rogers ,  Milan Patel

IPC分类号： G16H10/20 ,  G16H15/00 ,  G16H20/10 ,  G16H20/70 ,  G16H40/67 ,  G16H40/20 ,  G16H50/50 ,  A61B5/00 ,  A61B5/11 ,  G08B7/06 ,  G08B21/18 ,  G09B19/00 ,  G06F3/0482 ,  G06F3/04847

CPC分类号： G16H10/20 ,  A61B5/0022 ,  A61B5/1118 ,  A61B5/411 ,  A61B5/4238 ,  A61B5/4255 ,  A61B5/4824 ,  A61B5/742 ,  A61B5/746 ,  G08B7/06 ,  G08B21/182 ,  G09B19/00 ,  G16H15/00 ,  G16H20/10 ,  G16H20/70 ,  G16H40/20 ,  G16H40/67 ,  G16H50/50 ,  G06F3/0482 ,  G06F3/04847

摘要： Systems and methods are provided for monitoring a user having a chronic gastrointestinal indication. A questionnaire regarding a plurality of conditions is provided on a repeating basis. Each such condition at least partly arises from the gastrointestinal indication. Questionnaire questions are each associated with a corresponding condition and provide an affordance that allows the user to select between low and high values in accordance with user association with the condition. Responses are stored in a data store associated with the user. A user requested report comprising a graphical quality of life measure of the user is provided based upon temporal questionnaire answers. Questionnaire information is communicated to a remote device for medical practitioner evaluation and computation of a temporal overall quality of life score based on a plurality of component quality of life scores, each of which is associated with a condition in the plurality of conditions.

公开(公告)号：US20180353133A1

公开(公告)日：2018-12-13

申请号：US16006093

申请日：2018-06-12

申请人： Entrack, Inc.

发明人： Mir A. Imran

IPC分类号： A61B5/00 ,  A61B5/03

CPC分类号： A61B5/6861 ,  A61B5/036 ,  A61B5/073 ,  A61B5/14539 ,  A61B5/4238 ,  A61B5/4255 ,  A61B2562/0247

摘要： Embodiments provide devices, systems and methods for measuring a gastric emptying (GE) parameter (GEP). Many embodiments provide a swallowable capsule having three electrodes one covered by a coating which remains in the stomach but is degraded in the small intestine (SI). The electrodes are coupled to circuitry such that when the capsule is in the stomach, current flow occurs between the first two electrodes generating a first signal and in the SI current flow occurs between the second and now uncovered third electrode generating a second signal. These two signals can be transmitted and analyzed externally or by an internal controller to determine a GEP e.g., GE time. The patient may wear an external device configured to receive and analyze the signals to determine GE time. Embodiments of the invention may be used to diagnose gastroparesis and provide patient's information on when to eat meals or administer insulin after eating.

公开(公告)号：US20180303402A1

公开(公告)日：2018-10-25

申请号：US15957103

申请日：2018-04-19

申请人： Juan Guilleuma

发明人： Juan Guilleuma

IPC分类号： A61B5/00 ,  A61B6/03 ,  A61B5/055 ,  A61B6/00 ,  A61B8/08 ,  A61B8/12 ,  A61F2/82 ,  A61F2/958 ,  A61B17/22 ,  A61M25/10

CPC分类号： A61B5/4255 ,  A61B5/0066 ,  A61B5/055 ,  A61B5/4836 ,  A61B5/4842 ,  A61B6/032 ,  A61B6/504 ,  A61B8/12 ,  A61B8/488 ,  A61B17/22 ,  A61B2017/00818 ,  A61B2017/22001 ,  A61F2/82 ,  A61F2/958 ,  A61M25/104

摘要： A method of determination of a cause of hemorrhoids in a subject includes a determination of the presence of hemorrhoids in the subject by visual inspection, and by one or more of a non-invasive medical imaging procedure and/or an intra-vascular visualization procedure, determining if there is an obstruction or occlusion in an iliac vein of the subject, and if so, determining that the hemorrhoids were caused by such obstruction or occlusion. If the obstruction or occlusion are determined to be the cause of the hemorrhoids, a procedure for compressing the obstruction or occlusion in the iliac vein of the subject, such as by angioplasty or stenting, is performed. After an appropriate time period, changes to the hemorrhoids in the subject are determined by a subsequent visual inspection.

公开(公告)号：US20180221622A1

公开(公告)日：2018-08-09

申请号：US15812969

申请日：2017-11-14

申请人： Fractyl Laboratories, Inc.

发明人： Harith Rajagopalan ,  Jay Caplan ,  Craig M. Gardner ,  J. Christopher Flaherty

IPC分类号： A61M25/00 ,  A61B18/08 ,  A61B18/14 ,  A61B18/18 ,  A61B5/00 ,  A61F5/00 ,  A61N7/00 ,  A61B17/00 ,  A61M25/04 ,  A61B18/02 ,  A61B18/00 ,  A61B90/00 ,  A61B18/24 ,  A61B18/06 ,  A61B17/02 ,  A61B5/055 ,  A61B18/04 ,  A61N7/02

CPC分类号： A61M25/00 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/055 ,  A61B5/4255 ,  A61B5/4836 ,  A61B5/6852 ,  A61B5/6885 ,  A61B17/00234 ,  A61B17/00491 ,  A61B17/0218 ,  A61B17/3478 ,  A61B18/02 ,  A61B18/06 ,  A61B18/082 ,  A61B18/1492 ,  A61B18/1815 ,  A61B18/24 ,  A61B2017/00004 ,  A61B2017/00022 ,  A61B2017/00199 ,  A61B2017/00269 ,  A61B2017/00818 ,  A61B2017/306 ,  A61B2018/00005 ,  A61B2018/00011 ,  A61B2018/00017 ,  A61B2018/00029 ,  A61B2018/00041 ,  A61B2018/0022 ,  A61B2018/00255 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00494 ,  A61B2018/00559 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00672 ,  A61B2018/00678 ,  A61B2018/00744 ,  A61B2018/00791 ,  A61B2018/00809 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00863 ,  A61B2018/00875 ,  A61B2018/00982 ,  A61B2018/0212 ,  A61B2018/046 ,  A61B2018/1861 ,  A61B2090/3908 ,  A61B2090/3933 ,  A61B2090/395 ,  A61B2218/002 ,  A61B2505/05 ,  A61B2560/0431 ,  A61B2562/227 ,  A61F5/0069 ,  A61F5/0079 ,  A61M25/0082 ,  A61M25/04 ,  A61M2210/1053 ,  A61M2210/1057 ,  A61M2210/1071 ,  A61M2210/1408 ,  A61N7/00 ,  A61N7/022

摘要： A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat polycystic ovarian syndrome (PCOS).