-
公开(公告)号：US20070265632A1
公开(公告)日：2007-11-15
申请号：US11431693
申请日：2006-05-10
Applicant: Jeffrey Scifert , Scott Boden , James Marotta
Inventor： Jeffrey Scifert , Scott Boden , James Marotta
IPC: A61B17/00
CPC classification number: A61B17/15 , A61B17/06166 , A61B17/68 , A61B17/72 , A61B50/30 , A61B2017/00464 , A61B2017/564 , A61B2050/005 , A61B2050/006 , A61B2090/061 , A61F2/0095 , A61F2/28 , A61F2002/2817 , A61F2002/2825 , A61F2002/30062 , A61F2002/30115 , A61F2002/30116 , A61F2002/30131 , A61F2002/30138 , A61F2002/30159 , A61F2002/30235 , A61F2002/30237 , A61F2002/30238 , A61F2002/30551 , A61F2002/30593 , A61F2002/30616 , A61F2002/30617 , A61F2002/30677 , A61F2002/30714 , A61F2002/30822 , A61F2002/30827 , A61F2002/30828 , A61F2002/30831 , A61F2002/3096 , A61F2002/4658 , A61F2210/0004 , A61F2230/0006 , A61F2230/0013 , A61F2230/0017 , A61F2230/0028 , A61F2230/0069 , A61F2250/0089 , A61F2250/0097 , A61F2310/00179 , A61F2310/00365 , A61L27/54 , A61L2300/222 , A61L2300/252 , A61L2300/402 , A61L2300/406 , A61L2300/41 , A61L2300/414 , A61L2300/432 , A61L2300/802
Abstract: A bone cutting template is disclosed and can include a body. A plurality of grooves can be formed along the body and each groove can correspond to an incremental length of the body. The bone cutting template can include a plurality of length stamps along the body. Each of the plurality of length stamps can be adjacent to a corresponding groove.
Abstract translation: 骨切割模板被公开并且可以包括身体。 可以沿着主体形成多个槽，并且每个槽可对应于主体的增量长度。 骨切割模板可以包括沿着身体的多个长度邮票。 多个长度标记中的每一个可以与相应的凹槽相邻。
-
公开(公告)号：US20070225219A1
公开(公告)日：2007-09-27
申请号：US11388250
申请日：2006-03-23
Applicant: Scott Boden , Jeffrey Scifert , James Marotta
Inventor： Scott Boden , Jeffrey Scifert , James Marotta
CPC classification number: A61M25/1011 , A61B17/7061 , A61B17/7098 , A61B17/72 , A61B17/7258 , A61B17/8808 , A61M25/007 , A61M25/0108 , A61M2025/1052
Abstract: An intramedullary drug delivery device is disclosed and can be inserted within a bone canal of a bone. The intramedullary drug delivery device can include a housing. A drug delivery region can be established along the housing. Also, the drug delivery region can be configured to substantially span a fracture within the bone.
Abstract translation: 公开了一种髓内药物输送装置，并且可以将其插入到骨的骨管内。 髓内药物递送装置可以包括壳体。 可以沿着房屋建立药物递送区域。 而且，药物递送区域可以构造成基本上跨越骨骼内的骨折。
-
公开(公告)号：US20070264300A1
公开(公告)日：2007-11-15
申请号：US11431475
申请日：2006-05-10
Applicant: Jeffrey Scifert , Scott Boden , James Marotta
Inventor： Jeffrey Scifert , Scott Boden , James Marotta
IPC: A61F2/00
CPC classification number: A61B17/15 , A61B17/06166 , A61B17/68 , A61B17/72 , A61B50/30 , A61B2017/00464 , A61B2017/564 , A61B2050/005 , A61B2050/006 , A61B2090/061 , A61F2/0095 , A61F2/28 , A61F2002/2817 , A61F2002/2825 , A61F2002/30062 , A61F2002/30115 , A61F2002/30116 , A61F2002/30131 , A61F2002/30138 , A61F2002/30159 , A61F2002/30235 , A61F2002/30237 , A61F2002/30238 , A61F2002/30551 , A61F2002/30593 , A61F2002/30616 , A61F2002/30617 , A61F2002/30677 , A61F2002/30714 , A61F2002/30822 , A61F2002/30827 , A61F2002/30828 , A61F2002/30831 , A61F2002/3096 , A61F2002/4658 , A61F2210/0004 , A61F2230/0006 , A61F2230/0013 , A61F2230/0017 , A61F2230/0028 , A61F2230/0069 , A61F2250/0089 , A61F2250/0097 , A61F2310/00179 , A61F2310/00365 , A61L27/54 , A61L2300/222 , A61L2300/252 , A61L2300/402 , A61L2300/406 , A61L2300/41 , A61L2300/414 , A61L2300/432 , A61L2300/802
Abstract: A therapeutic agent carrier for treating a defect in a bone is disclosed and can include a body that can be configured to approximate a portion of the bone. Further, the therapeutic agent carrier can include a plurality of grooves formed along the body. Each groove can correspond to an incremental length of the body. The therapeutic agent carrier can also include a plurality of dosage stamps along the body and each of the plurality of dosage stamps is adjacent to a corresponding to groove.
Abstract translation: 公开了一种用于治疗骨缺损的治疗剂载体，并且可以包括可构造为近似骨的一部分的主体。 此外，治疗剂载体可以包括沿着身体形成的多个凹槽。 每个凹槽可以对应于身体的增量长度。 治疗剂载体还可以包括沿着身体的多个剂量标记，并且多个剂量标记中的每一个与对应的凹槽相邻。
-
公开(公告)号：US20070225811A1
公开(公告)日：2007-09-27
申请号：US11386460
申请日：2006-03-22
Applicant: Jeffrey Scifert , Scott Boden
Inventor： Jeffrey Scifert , Scott Boden
CPC classification number: A61F2/4425 , A61F2/4611 , A61F2002/2817 , A61F2002/30649 , A61F2002/30677 , A61F2002/30836 , A61F2002/30884 , A61F2002/30925 , A61F2002/443 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00293 , A61F2310/00365 , A61F2310/0097 , A61F2310/00976
Abstract: Compound orthopedic implants, intervertebral prosthetic implants and methods of treating a patient are provided. In an exemplary embodiment, a compound orthopedic implant comprises a first conformable body and a second conformable body overlying the first conformable body. The compound orthopedic implant can function as a conformable carrier for delivering a therapeutic agent to an orthopedic site.
Abstract translation: 提供复合骨科植入物，椎间假体植入物和治疗患者的方法。 在示例性实施例中，复合整形外科植入物包括第一适形身体和覆盖第一适形身体的第二适形身体。 复合整形外科植入物可用作将治疗剂递送至矫形部位的适形载体。
-
公开(公告)号：US09220598B2
公开(公告)日：2015-12-29
申请号：US12705253
申请日：2010-02-12
Applicant: Randal R. Betz , Scott Boden , Munish Chandra Gupta , Michael F. O'Brien , Harvinder Sandhu , Alexis Shelokov , Georgiana Shelokov , Daryl R. Sybert , Alexander Vaccaro , Guobao Wei , Todd M. Boyce , Robert Cohen , Cristy Richards , Lawrence A. Shimp
Inventor： Randal R. Betz , Scott Boden , Munish Chandra Gupta , Michael F. O'Brien , Harvinder Sandhu , Alexis Shelokov , Daryl R. Sybert , Alexander Vaccaro , Guobao Wei , Todd M. Boyce , Robert Cohen , Cristy Richards , Lawrence A. Shimp
CPC classification number: A61B17/8819 , A61B17/823 , A61B17/8825 , A61B2017/8813 , A61F2/30 , A61F2/4603 , A61F2002/0086 , A61F2002/2825 , A61F2002/2835 , A61F2002/30059 , A61F2002/30064 , A61F2002/3007 , A61F2002/30072 , A61F2002/30588 , A61F2002/30677 , A61F2002/3068 , A61F2002/3093 , A61F2002/30971 , A61F2002/4623 , A61F2002/4627 , A61F2250/0068 , A61F2310/00592 , A61F2310/00958 , A61F2310/0097
Abstract: A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust the release of the substance. In various embodiments, the covering is suitable for a variety of procedure specific uses. Implantation tools may be provided for placing the covering at a surgical site. Kits may be provided including variously sized or shaped coverings and one or more tools for use in placing the covering.
Abstract translation: 提供了将物质或材料输送到手术部位的覆盖物。 其中提供的物质的覆盖物可以被称为递送系统。 通常，覆盖物可以是能够至少部分地保留其中提供的物质的单室或多室结构，直到覆盖物被放置在手术部位。 放置时，覆盖物可以促进物质或周围材料的转移。 例如，物质可以被主动地或被动地释放到手术部位。 覆盖物可以参与，控制或以其他方式调节物质的释放。 在各种实施例中，覆盖物适用于各种程序特定用途。 可以提供植入工具用于将覆盖物放置在手术部位。 可以提供包括各种尺寸或形状的覆盖物和用于放置覆盖物的一个或多个工具的套件。
-
Patent Agency Ranking
公开(公告)号：US20100268232A1
公开(公告)日：2010-10-21
申请号：US12705253
申请日：2010-02-12
Applicant: Randal R. Betz , Scott Boden , Munish Chandra Gupta , Michael F. O'Brien , Harvinder Sandhu , Alexis Shelokov , Georgiana Shelokov , Daryl R. Sybert , Alexander Vaccaro , Guobao Wei , Todd M. Boyce , Robert Cohen , Cristy Richards , Lawrence A. Shimp
Inventor： Randal R. Betz , Scott Boden , Munish Chandra Gupta , Michael F. O'Brien , Harvinder Sandhu , Alexis Shelokov , Georgiana Shelokov , Daryl R. Sybert , Alexander Vaccaro , Guobao Wei , Todd M. Boyce , Robert Cohen , Cristy Richards , Lawrence A. Shimp
CPC classification number: A61B17/8819 , A61B17/823 , A61B17/8825 , A61B2017/8813 , A61F2/30 , A61F2/4603 , A61F2002/0086 , A61F2002/2825 , A61F2002/2835 , A61F2002/30059 , A61F2002/30064 , A61F2002/3007 , A61F2002/30072 , A61F2002/30588 , A61F2002/30677 , A61F2002/3068 , A61F2002/3093 , A61F2002/30971 , A61F2002/4623 , A61F2002/4627 , A61F2250/0068 , A61F2310/00592 , A61F2310/00958 , A61F2310/0097
Abstract: A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust the release of the substance. In various embodiments, the covering is suitable for a variety of procedure specific uses. Implantation tools may be provided for placing the covering at a surgical site. Kits may be provided including variously sized or shaped coverings and one or more tools for use in placing the covering.
Abstract translation: 提供了将物质或材料输送到手术部位的覆盖物。 其中提供的物质的覆盖物可以被称为递送系统。 通常，覆盖物可以是能够至少部分地保留其中提供的物质的单室或多隔室结构，直到将覆盖物放置在手术部位。 放置时，覆盖物可以促进物质或周围材料的转移。 例如，物质可以被主动地或被动地释放到手术部位。 覆盖物可以参与，控制或以其他方式调节物质的释放。 在各种实施例中，覆盖物适用于各种程序特定用途。 可以提供植入工具用于将覆盖物放置在手术部位。 可以提供包括各种尺寸或形状的覆盖物和用于放置覆盖物的一个或多个工具的套件。
-
公开(公告)号：US20070099176A1
公开(公告)日：2007-05-03
申请号：US11545349
申请日：2006-10-10
Applicant: Scott Boden , Sreedhara Sangadala , F. Titus , William McKay
Inventor： Scott Boden , Sreedhara Sangadala , F. Titus , William McKay
IPC: C12Q1/00 , C07H21/04 , C12P21/06 , C07K14/705 , C12N15/86
CPC classification number: A61L27/3856 , A61K35/12 , A61K35/13 , A61K48/00 , A61K2121/00 , C07K14/47 , C07K14/78 , C07K16/18 , C12N2799/022
Abstract: Methods of expressing LIM mineralization protein in mammalian cells are described. Methods of expressing LIM mineralization protein and assessing glycosylation of the LIM mineralization protein in prokaryotic and non-mammalian eukaryotic cells are also described. The methods involve transfecting the cells with an isolated nucleic acid comprising a nucleotide sequence encoding a LIM mineralization protein. Transfection may be accomplished in vitro, ex vivo or in vivo by direct injection of virus or naked DNA, or by a nonviral vector such as a plasmid.
Abstract translation: 描述了在哺乳动物细胞中表达LIM矿化蛋白的方法。 还描述了在原核和非哺乳动物真核细胞中表达LIM矿化蛋白和评估LIM矿化蛋白的糖基化的方法。 所述方法包括用包含编码LIM矿化蛋白的核苷酸序列的分离的核酸转染细胞。 转染可以通过直接注射病毒或裸露DNA或非病毒载体如质粒在体外，离体或体内完成。
-
公开(公告)号：US20100239545A9
公开(公告)日：2010-09-23
申请号：US10292951
申请日：2002-11-13
Applicant: William McKay , Scott Boden , Sangwook Yoon
Inventor： William McKay , Scott Boden , Sangwook Yoon
CPC classification number: A61K48/005 , A61K35/12 , A61K35/13 , A61K48/00 , A61K2121/00 , A61L27/3804 , A61L27/3856 , C07K14/47 , C07K14/4702 , C07K14/78 , C07K16/18 , C12N2799/022
Abstract: Methods of expressing LIM mineralization protein in non-osseous mammalian cells, such as stem cells or intervertebral disc cells (e.g., cells of the annulus fibrosus, or cells of the nucleus pulposus) are described. The methods involve transfecting the cells with an isolated nucleic acid comprising a nucleotide sequence encoding a LIM mineralization protein operably linked to a promoter. Transfection may be accomplished ex vivo or in vivo by direct injection of virus or naked DNA, or by a nonviral vector such as a plasmid. Expression of the LIM mineralization protein can stimulate proteoglycan and/or collagen production in cells capable of producing proteoglycyan and/or collagen. Methods for treating disc disease associated with trauma or disc degeneration are also described.
Abstract translation: 描述了在非骨骼哺乳动物细胞中表达LIM矿化蛋白的方法，例如干细胞或椎间盘细胞（例如，纤维环的细胞或髓核的细胞）。 所述方法涉及用分离的核酸转染细胞，所述分离的核酸包含可操作地连接到启动子的编码LIM矿化蛋白的核苷酸序列。 转染可以通过直接注射病毒或裸露DNA或非病毒载体如质粒在体内或体内完成。 LIM矿化蛋白的表达可以刺激能够产生蛋白多糖和/或胶原的细胞中的蛋白聚糖和/或胶原产生。 还描述了与创伤或椎间盘退变相关的椎间盘疾病的治疗方法。
-
9.发明申请公开(公告)号：US20070027081A1
公开(公告)日：2007-02-01
申请号：US11385612
申请日：2006-03-21
Applicant: Jeffrey Marx , William McKay , Scott Boden
Inventor： Jeffrey Marx , William McKay , Scott Boden
CPC classification number: A61K38/1709 , A61K38/1875 , A61K2300/00
Abstract: The present invention relates to the methods and compositions for the treatment of subjects having compromised bone conditions. Specifically, the invention relates to combinatorial therapeutic strategies including small molecules and peptide mimics of LIM mineralization proteins, particularly LMP-1, to overcome the dose-related translational barriers for BMP-2 therapeutics.
Abstract translation: 本发明涉及用于治疗受损骨患者的方法和组合物。 具体地，本发明涉及包括LIM矿化蛋白（特别是LMP-1）的小分子和肽模拟物的组合治疗策略，以克服BMP-2治疗剂的剂量相关翻译屏障。
-
公开(公告)号：US5891147A
公开(公告)日：1999-04-06
申请号：US939848
申请日：1997-09-29
Applicant: Peter A. Moskovitz , Scott Boden , William F. McKay , Joseph Moctezuma
Inventor： Peter A. Moskovitz , Scott Boden , William F. McKay , Joseph Moctezuma
IPC: A61B17/00 , A61B17/02 , A61B17/16 , A61B17/32 , A61B18/14 , A61F2/00 , A61F2/02 , A61F2/28 , A61F2/44 , A61F2/46 , A61F5/00
CPC classification number: A61F2/4611 , A61B17/02 , A61B17/0206 , A61B17/025 , A61B17/1604 , A61B17/1606 , A61B17/1608 , A61B17/1637 , A61F2/4455 , A61F2/4601 , A61B18/1442 , A61B2017/00261 , A61B2017/0042 , A61B2017/0256 , A61B2017/320044 , A61F2002/2835 , A61F2002/30062 , A61F2002/30153 , A61F2002/30261 , A61F2002/4623 , A61F2002/4635 , A61F2002/4649 , A61F2210/0004 , A61F2230/0019 , A61F2230/0082 , A61F2310/00293 , Y10S606/907
Abstract: Minimally invasive spinal surgical techniques and tools are provided. The methods include separating the iliocostalis lumborum muscle from the anterior leaf of the thoracolumbar fascia to create a channel from the patient's skin to the intertransverse interval. In one embodiment, the method also includes delivering graft material through the channel to the intertransverse interval. A device according to one aspect of the present invention includes a retraction portion having a flattened plate configured to atraumatically retract tissue to create a working space within an endosurgical site and a curved shaft attached to the retraction portion. The shaft includes a bend having a radius of preferably 160 degrees. A gripping portion is attached to the shaft and is configured for manually gripping and manipulating the device.
Abstract translation: 提供微创脊柱外科技术和工具。 这些方法包括从胸腰肌筋膜前叶分离髂骨肌肉肌肉，以创建从患者皮肤到横向间隔的通道。 在一个实施方案中，该方法还包括将移植材料通过该通道输送到跨越间隔。 根据本发明的一个方面的装置包括具有扁平板的收缩部分，所述扁平板被构造成无损伤地收缩组织以在外科手术部位内产生工作空间，以及附接到所述缩回部分的曲轴。 轴包括具有优选为160度的半径的弯曲部。 抓握部分附接到轴上并被构造成手动地夹持和操纵装置。
-
-
-
-
-
-
-
-
-
Search Results
26
records
(took 0.022 seconds)
