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1.发明申请公开(公告)号：US20190016715A1
公开(公告)日：2019-01-17
申请号：US15950683
申请日：2018-04-11
IPC分类号： C07D417/14 , C07D231/12 , C07D403/12 , C07D263/32 , C07D277/26 , C07D307/38 , C07D333/24 , C07D401/14 , C07D405/10 , C07D409/02 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/10 , A61K31/505 , A61K31/506 , C07D233/64 , C07D285/08 , C07D277/20 , C07D249/08 , C07D417/04 , C07D217/06 , A61K31/433 , A61K31/427 , A61K31/426 , A61K31/4196 , C07D277/30 , C07D275/02 , C07D271/06 , C07D243/12 , C07D409/04 , C07D239/26 , C07D405/04 , C07D403/10 , C07D401/12 , C07D401/10 , C07D401/04 , C07D233/54 , C07D261/08
CPC分类号： C07D243/14 , A61K31/4196 , A61K31/426 , A61K31/427 , A61K31/433 , A61K31/505 , A61K31/506 , A61P25/00 , C07D217/06 , C07D231/12 , C07D233/54 , C07D233/64 , C07D239/26 , C07D243/12 , C07D249/08 , C07D261/08 , C07D263/32 , C07D271/06 , C07D275/02 , C07D277/20 , C07D277/26 , C07D277/30 , C07D285/08 , C07D307/38 , C07D333/24 , C07D401/04 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/10 , C07D409/02 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/10 , C07D417/14
摘要： Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor negative allosteric modulators (NAMs), compositions comprising the compounds, and methods of using the compounds and compositions.
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2.发明申请Metabotropic Glutamate Receptor Positive Allosteric Modulators (PAMS) and Uses Thereof 审中-公开代谢型谷氨酸受体阳性变构调节剂（PAMS）及其用途公开(公告)号：US20170036987A1
公开(公告)日：2017-02-09
申请号：US15301697
申请日：2015-04-06
IPC分类号： C07C65/40 , C07D311/16 , C07C69/92 , C07C255/56 , C07D257/04 , C07F5/04 , C07C259/10 , C07C311/51 , C07F5/02 , C07C251/48 , C07D271/07 , C07D285/08 , C07D295/16 , C07C235/46 , C07C49/84 , C07D213/50 , C07D295/26 , C07C235/54 , C07D307/54 , C07D213/55 , C07D277/24 , C07D333/24 , C07D241/12 , C07D285/12 , C07D239/26 , C07D307/68 , C07D213/80 , C07D213/79 , C07D241/24 , C07D213/64 , C07D213/70 , C07C59/90
CPC分类号： C07C65/40 , C07C49/84 , C07C59/90 , C07C65/05 , C07C65/10 , C07C69/92 , C07C235/46 , C07C235/54 , C07C251/48 , C07C255/56 , C07C259/10 , C07C311/51 , C07C2601/02 , C07C2601/08 , C07D213/50 , C07D213/55 , C07D213/64 , C07D213/68 , C07D213/70 , C07D213/79 , C07D213/80 , C07D239/26 , C07D241/12 , C07D241/24 , C07D257/04 , C07D271/06 , C07D271/07 , C07D277/24 , C07D285/08 , C07D285/12 , C07D295/108 , C07D295/16 , C07D295/26 , C07D307/42 , C07D307/54 , C07D307/68 , C07D311/16 , C07D333/24 , C07F5/025 , C07F5/04 , C07F7/025
摘要： Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor positive allosteric modulators (PAMS), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.
摘要翻译： 本文提供的是小分子活性代谢型谷氨酸亚型2和-3受体阳性变构调节剂（PAMS），包含该化合物的组合物，以及使用包含该化合物的化合物和组合物的方法。
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公开(公告)号：US20170217951A1
公开(公告)日：2017-08-03
申请号：US15315363
申请日：2015-06-09
IPC分类号： C07D417/14 , C07D277/26 , C07D417/04 , C07D417/10 , C07D285/08 , C07D275/02 , C07D333/24 , C07D307/38 , C07D263/32 , C07D271/06 , C07D261/08 , C07D249/08 , C07D409/04 , C07D401/04 , C07D405/04 , C07D405/10 , C07D233/64 , C07D231/12 , C07D409/14 , C07D239/26 , C07D413/04 , C07D401/14 , C07D413/14 , C07D403/12 , C07D401/10 , C07D243/12 , C07D277/30
CPC分类号： C07D417/14 , A61K31/4196 , A61K31/426 , A61K31/427 , A61K31/433 , A61K31/505 , A61K31/506 , C07D217/06 , C07D231/12 , C07D233/54 , C07D233/64 , C07D239/26 , C07D243/12 , C07D249/08 , C07D261/08 , C07D263/32 , C07D271/06 , C07D275/02 , C07D277/20 , C07D277/26 , C07D277/30 , C07D285/08 , C07D307/38 , C07D333/24 , C07D401/04 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/10 , C07D409/02 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/10
摘要： Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor negative allosteric modulators (NAMs), compositions comprising the compounds, and methods of using the compounds and compositions.
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